Faith in the Republic: A Frances Lewis Law Center Conversation

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PENERAPAN KONSEP GREEN BUILDING PADA INDUSTRI JASA KONSTRUKSI DI MANADO

Konsep green building merupakan satu inovasi dari sektor konstruksi di seluruh dunia dalam rangka meminimalisir pemanasan global yang terjadi akhir-akhir ini. Dimana konsep ini menuntut suatu bangunan unutk lebih memperhatikan aspek lingkungan dan juga penghematan energi. Green building telah gencar diterapkan di seluruh dunia dan sedang didorong untuk menjadi trend bagi pengembang property saat ini. Namun, di Indonesia sendiri green building baru diterapkan di beberapa kota besar seperti Jakarta, Surabaya, dan Yogyakarta. Tujuan dari penelitian ini adalah unutk mendapatkan persentase mengenai pengetahuan umum para pelaku jasa konstruksi di Manado mengenai green building, dan untuk mendapatkan informasi mengenai kendala apa saja yang dihadapi oleh para pelaku jasa konstruksi di Manado mengenai penerapan green building di Manado, dan untuk mengetahui faktor-faktor pendukung penerapan konsep green building di Manado.Penelitian ini dilakukan dengan metode kuesioner, yaitu dengan data yang secara langsung dikumpul oleh peneliti dari lapangan. Dan untuk pengolahan data, dilakukan dengan metode deskriptif.Hasil penelitian menunjukan bahwa faktor kendala para pelaku jasa konstruksi di Manado dalam menerapkan konsep green building di Manado adalah kurangnya pemahaman mengenai green building, tidak dikenalnya produk-produk bahan bangunan yang berlabel ramah lingkungan (eco-label), serta kurangnya studi-studi kasus dan penelitian tentang green building. Dan untuk pengetahuan para pelaku jasa konstruksi di Manado mengenai green building, diperoleh bahwa green building sudah bukan istilah yang asing bagi para pelaku jasa konstruksi di Manado. Para pelaku jasa kosntruksi di Manado baru mengetahui definisi dan pengertian green building. Namun belum begitu memahami manfaat, alasan penerapan, serta metode pelaksanaan dari konsep green building. Kata Kunci: Green building, Konstruksi, Pemanasan Globa

PROSPEK PENGEMBANGAN USAHA TERNAK SAPI POTONG DI KECAMATAN BOLANGITANG TIMUR KABUPATEN BOLAANG MONGONDOW UTARA

ABSTRACT THE PROSPECT OF BEEF CATLE INDUSTRY DEVELOPMENTIN EAST BOLANGITANG DISTRICT, NORTH BOLAANG MONGONDOW REGENCY The purpose of this research was to find out the potential resources on beef cattle industry development in East Bolangitangdistrict, North Bolaang Mongondow regency. Survey method (questionnaire) was used in order to get primary and secondary data, from June until July, 2015. All the data taken were then analyzed using SWOT and Land Carrying Capacity analysis, as well as descriptive analysis.  It was found in this research that, the maximum potency of livestock units based on dry land, savannah and swampland (wetland) resources amounted to 8.879 ST (Satuan Ternak). This number depicted that the district of East Bolangitang potential to develop cattle industry   Keywords: Cattle, prospects, Business Developmen

STAT1 activation in association with JAK2 exon 12 mutations

La inclusión de la perspectiva de género en la actividad jurisdiccional es una demanda sostenida de los colectivos feministas y de mujeres, dado que las sentencias tienen un poder performativo y envían un mensaje a la sociedad: “[…] tienen un poder individual y colectivo que impactan en la vida de las personas y conforman la identidad del poder judicial como un actor imprescindible en la construcción de un Estado democrático de derecho” (Suprema Corte de Justicia de la Nación, 2013:7). La incorporación de la perspectiva de género viene a garantizar la igualdad de posiciones (Kessler, 2014) entre mujeres y varones como una meta, trascendiendo la mera igualdad de oportunidades que hasta el presente se ha demostrado insuficiente para que las mujeres consigamos una ciudadanía plena. Al momento de incorporar la perspectiva de género en las sentencias, quienes juzgan deben tener presente en primer lugar, el impacto diferenciado de las normas en base al sexo de las personas. En segundo lugar, la interpretación y aplicación de las leyes en relación con (y en base a) estereotipos de género. Si, por ejemplo, quienes imparten justicia no tienen presentes los estereotipos de género vigentes detrás de las violaciones a los derechos humanos de las mujeres, si no los detectan ni cuestionan, entonces los reproducen. Tal como sostiene Scott (1996) el género es una categoría imprescindible para el análisis social. En tercer lugar, al momento del juzgamiento, se deben tener en cuenta las exclusiones legitimadas por la ley por pensar el mundo en términos binarios y androcéntricos; en cuarto lugar, la distribución no equitativa de recursos y poder que opera entre varones y mujeres en el marco de una organización social patriarcal, y, por último, el trato diferenciado por género legitimado por las propias leyes.Eje 3: Tramas violentas y espacios de exclusión.Instituto de Cultura Jurídic

mHealth optimisation for education and physical activity in Type 1 diabetes: MEDPAT1.

Aims: To develop and evaluate usability of prototype personalised prediction algorithms for people with Type 1 diabetes to optimise blood glucose control associated with physical activity using smart phone technology. To explore the potential to build a knowledge repository founded on case-based reasoning and linkage with an online structured education programme that will increase confidence and levels of participation in physical activity

Delayed diagnosis of cystic fibrosis associated with R117H on a background of 7T polythymidine tract at intron 8

AbstractWe report late diagnoses of cystic fibrosis (CF) in two men aged 61 and 65 years. At the time of presentation, both patients had significant pulmonary disease. In each case two CFTR gene mutations were identified, including R117H on a background of a poly T genotype of 7T/9T. Patients with two identified CFTR mutations which include the R117H/7T anomaly should be followed up routinely as they remain susceptible to severe lung disease

Absence of system xc⁻ on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis

Background: Multiple sclerosis (MS) is an autoimmune demyelinating disease that affects the central nervous system (CNS), leading to neurodegeneration and chronic disability. Accumulating evidence points to a key role for neuroinflammation, oxidative stress, and excitotoxicity in this degenerative process. System x(c)- or the cystine/glutamate antiporter could tie these pathological mechanisms together: its activity is enhanced by reactive oxygen species and inflammatory stimuli, and its enhancement might lead to the release of toxic amounts of glutamate, thereby triggering excitotoxicity and neurodegeneration. Methods: Semi-quantitative Western blotting served to study protein expression of xCT, the specific subunit of system x(c)-, as well as of regulators of xCT transcription, in the normal appearing white matter (NAWM) of MS patients and in the CNS and spleen of mice exposed to experimental autoimmune encephalomyelitis (EAE), an accepted mouse model of MS. We next compared the clinical course of the EAE disease, the extent of demyelination, the infiltration of immune cells and microglial activation in xCT-knockout (xCT(-/-)) mice and irradiated mice reconstituted in xCT(-/-) bone marrow (BM), to their proper wild type (xCT(+/+)) controls. Results: xCT protein expression levels were upregulated in the NAWM of MS patients and in the brain, spinal cord, and spleen of EAE mice. The pathways involved in this upregulation in NAWM of MS patients remain unresolved. Compared to xCT(+/+) mice, xCT(-/-) mice were equally susceptible to EAE, whereas mice transplanted with xCT(-/-) BM, and as such only exhibiting loss of xCT in their immune cells, were less susceptible to EAE. In none of the above-described conditions, demyelination, microglial activation, or infiltration of immune cells were affected. Conclusions: Our findings demonstrate enhancement of xCT protein expression in MS pathology and suggest that system x(c)- on immune cells invading the CNS participates to EAE. Since a total loss of system x(c)- had no net beneficial effects, these results have important implications for targeting system x(c)- for treatment of MS

National Variation in Use of Immunosuppression for Kidney Transplantation: A Call for Evidence‐Based Regimen Selection

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/133631/1/ajt13758_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/133631/2/ajt13758.pd