Water Quality Trends across Select 319 Monitoring Sites in Northwest Arkansas

Northwest Arkansas contains two 319 priority watersheds that the Arkansas Natural Resources Commission has identified as being impacted by point source and nonpoint source pollution (i.e., phosphorus, nitrogen, and sediment). This project specifically focused on determining water quality trends at select sites within the Illinois River (HUC# 11110103) and Beaver Reservoir (HUC# 11010001) priority watersheds, including Ballard Creek, Osage Creek, Illinois River, White River, West Fork White River and the Kings River where sufficient constituent data were available. Water quality trends were analyzed using flow‐adjusted constituent concentrations of phosphorus, nitrogen, sediment, sulfate and chloride, and parametric and non‐parametric statistical techniques to determine if constituent concentrations were increasing, decreasing or not significantly changing over time. Overall, flow‐adjusted concentrations of phosphorus and sediment have been decreasing across these watersheds based upon both statistical approaches. The decrease in phosphorus was likely the most important observation, because most water quality concerns in this region have focused on elevated phosphorus concentrations in these transboundary watersheds. These trends can be used along with other watershed information to improve the knowledge of how past, current, and future management decisions have influenced the watershed

Handbook of Best Management Practices for the Upper Illinois River Watershed and Other Regional Watersheds

Management actions are strategies carried out by stakeholders that are designed to implement water quality protection and restoration activities with a watershed. This publication presents a range of beneficial management actions from simple to complex that address the pollutant potential that is common across the watershed landscape of northwest Arkansas. Some management actions can be undertaken by any watershed stakeholder at any time, while others need to be carefully planned or lobbied to local and state government. The following chapters address potential management actions that can be taken by individuals or groups at households, businesses, institutions, municipalities, industrial facilities, farms, and construction sites to maintain or improve water quality in northwest Arkansas. This publication serves as companion material to MSC Publication 355, Final Report to the Illinois River Watershed Partnership: Recommended Watershed Based Strategy for the Upper Illinois River Watershed, Northwest Arkansas. However, the practices and programs described within this publication are also relevant to other regional watersheds

Water Quality and Watershed Conditions in the Upper Illinois River Watershed

The Illinois River and its tributaries have many uses that have been designated by the Arkansas Department of Environmental Quality including fisheries, aquatic life, primary contact waters, secondary contact waters, drinking water supply, and agricultural and industrial water supply, and water quality affects whether these uses can be supported. Since water quality can be quite complex, many types of measurements can be used as water quality indicators; some common water quality measurements include pH, dissolved oxygen concentration, and conductivity. More complicated measurements include determining nutrients, sediment and bacteria in the water, as well as assessing the aquatic life—aquatic insects, fish, algae and plants that are present within a stream. Most of these parameters are related to the type and use of land surrounding the stream and thus can be impacted by human activities. This publication details stream use classification and use support, impaired reaches in the Arkansas portion of the Illinois River, general water quality conditions across the Upper Illinois River Watershed, and trends in water quality in the Illinois River over the past decade. This publication serves as companion material to MSC Publication 355, Final Report to the Illinois River Watershed Partnership: Recommended Watershed Based Strategy for the Upper Illinois River Watershed, Northwest Arkansa

Final Report to the Illinois River Watershed Partnership: Recommended Watershed Based Strategy for the Upper Illinois River Watershed, Northwest Arkansas

This publication serves as the final report to the Illinois River Watershed Partnership (IRWP) regarding the project entitled “Development of the Watershed Management Plan for the Upper Illinois River”. This document was intended to provide this stakeholder based organization guidance in the development of a watershed management plan for the Illinois River drainage area (i.e., the Upper Illinois River Watershed, UIRW) in Arkansas. This document represents the final report from the Arkansas Water Resources Center (AWRC) and affiliated project investigators, and the IRWP may alter this document before the final submission of its watershed management plan to the Arkansas Natural Resources Commission (ANRC) and the U.S. Environmental Protection Agency

Additive drug-specific and sex-specific risks associated with co-use of marijuana and tobacco during pregnancy: Evidence from 3 recent developmental cohorts (2003-2015).

BACKGROUND: Methodologic challenges related to the concomitant use (co-use) of substances and changes in policy and potency of marijuana contribute to ongoing uncertainty about risks to fetal neurodevelopment associated with prenatal marijuana use. In this study, we examined two biomarkers of fetal neurodevelopmental risk-birth weight and length of gestation-associated with prenatal marijuana use, independent of tobacco (TOB), alcohol (ALC), other drug use (OTH), and socioeconomic risk (SES), in a pooled sample (N = 1191) derived from 3 recent developmental cohorts (2003-2015) with state-of-the-art substance use measures. We examined differential associations by infant sex, and multiplicative effects associated with co-use of MJ and TOB. METHODS: Participants were mother-infant dyads with complete data on all study variables derived from Growing Up Healthy (n = 251), Behavior and Mood in Babies and Mothers (Cohorts 1 and 2; n = 315), and the Early Growth and Development Study (N = 625). We estimated direct effects on birth weight and length of gestation associated with MJ, TOB, and co-use (MJ x TOB), using linear regression analysis in the full sample, and in male (n = 654) and female (n = 537) infants, separately. RESULTS: Mean birth weight and length of gestation were 3277 g (SD = 543) and 37.8 weeks (SD = 2.0), respectively. Rates of prenatal use were as follows: any use, n = 748 (62.8%); MJ use, n = 273 (22.9%); TOB use, n = 608 (51.0%); co-use of MJ and TOB, n = 230 (19.3%); ALC use, n = 464 (39.0%); and OTH use n = 115 (9.7%.) For all infants, unique effects on birth weight were observed for any MJ use [B(SE) = -84.367(38.271), 95% C.I. -159.453 to -9.281, p = .028], any TOB use [B(SE) = -0.99.416(34.418), 95% C.I. -166.942 to -31.889, p = .004], and each cigarette/day in mean TOB use [B(SE) = -12.233(3.427), 95% C.I. -18.995 to -5.510, p \u3c .001]. Additional effects of co-use on birth weight, beyond these drug-specific effects, were not supported. In analyses stratified by sex, while TOB use was associated with lower birth weight in both sexes, MJ use during pregnancy was associated with lower birth weight of male infants [B(SE) = -153.1 (54.20); 95% C.I. -259.5 to -46.7, p = .005], but not female infants [B(SE) = 8.3(53.1), 95% C.I. -96.024 to 112.551, p = .876]. TOB, MJ, and their co-use were not associated with length of gestation. CONCLUSIONS: In this sample, intrauterine co-exposure to MJ and TOB was associated with an estimated 18% reduction in birth weight not attributable to earlier delivery, exposure to ALC or OTH drugs, nor to maternal SES. We found evidence for greater susceptibility of male fetuses to any prenatal MJ exposure. Examination of dose-dependence in relationships found in this study, using continuous measures of exposure, is an important next step. Finally, we underscore the need to consider (a) the potential moderating influence of fetal sex on exposure-related neurodevelopmental risks; and (b) the importance of quantifying expressions of risk through subtle alterations, rather than dichotomous outcomes

Case Study of Resilient Baton Rouge: Applying Depression Collaborative Care and Community Planning to Disaster Recovery.

BackgroundAddressing behavioral health impacts of major disasters is a priority of increasing national attention, but there are limited examples of implementation strategies to guide new disaster responses. We provide a case study of an effort being applied in response to the 2016 Great Flood in Baton Rouge.MethodsResilient Baton Rouge was designed to support recovery after major flooding by building local capacity to implement an expanded model of depression collaborative care for adults, coupled with identifying and responding to local priorities and assets for recovery. For a descriptive, initial evaluation, we coupled analysis of documents and process notes with descriptive surveys of participants in initial training and orientation, including preliminary comparisons among licensed and non-licensed participants to identify training priorities.ResultsWe expanded local behavioral health service delivery capacity through subgrants to four agencies, provision of training tailored to licensed and non-licensed providers and development of advisory councils and partnerships with grassroots and government agencies. We also undertook initial efforts to enhance national collaboration around post-disaster resilience.ConclusionOur partnered processes and lessons learned may be applicable to other communities that aim to promote resilience, as well as planning for and responding to post-disaster behavioral health needs

Personality, conventional Christian belief and unconventional paranormal belief : a study among teenagers

A sample of 10,851 pupils (5493 males and 5358 females) attending Year 9 classes (13- to 14-year-olds) and a sample of 9494 pupils (4787 males and 4707 females) attending Year 10 classes (14- to 15-year-olds) in non-denominational state-maintained secondary schools in England and Wales completed questions concerned with conventional Christian belief and unconventional paranormal belief, alongside the short-form Junior Eysenck Personality Questionnaire. The data demonstrated that conventional Christian belief and unconventional paranormal belief occupy different locations in relation to the Eysenckian model of personality in respect of the psychoticism scale and the lie scale. While conventional Christian belief is associated with lower psychoticism scores and higher lie scale scores (greater social conformity), unconventional paranormal belief is associated with higher psychoticism scores and lower lie scale scores (lower social conformity)

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

Expansion of the polyglutamine repeat within the protein Huntingtin (Htt) causes Huntington's disease, a neurodegenerative disease associated with aging and the accumulation of mutant Htt in diseased neurons. Understanding the mechanisms that influence Htt cellular degradation may target treatments designed to activate mutant Htt clearance pathways. We find that Htt is phosphorylated by the inflammatory kinase IKK, enhancing its normal clearance by the proteasome and lysosome. Phosphorylation of Htt regulates additional post-translational modifications, including Htt ubiquitination, SUMOylation, and acetylation, and increases Htt nuclear localization, cleavage, and clearance mediated by lysosomal-associated membrane protein 2A and Hsc70. We propose that IKK activates mutant Htt clearance until an age-related loss of proteasome/lysosome function promotes accumulation of toxic post-translationally modified mutant Htt. Thus, IKK activation may modulate mutant Htt neurotoxicity depending on the cell's ability to degrade the modified species

The Value of Information for Populations in Varying Environments

The notion of information pervades informal descriptions of biological systems, but formal treatments face the problem of defining a quantitative measure of information rooted in a concept of fitness, which is itself an elusive notion. Here, we present a model of population dynamics where this problem is amenable to a mathematical analysis. In the limit where any information about future environmental variations is common to the members of the population, our model is equivalent to known models of financial investment. In this case, the population can be interpreted as a portfolio of financial assets and previous analyses have shown that a key quantity of Shannon's communication theory, the mutual information, sets a fundamental limit on the value of information. We show that this bound can be violated when accounting for features that are irrelevant in finance but inherent to biological systems, such as the stochasticity present at the individual level. This leads us to generalize the measures of uncertainty and information usually encountered in information theory

Are two better than one? Analysis of an FtsK/Xer recombination system that uses a single recombinase

Bacteria harbouring circular chromosomes have a Xer site-specific recombination system that resolves chromosome dimers at division. In Escherichia coli, the activity of the XerCD/dif system is controlled and coupled with cell division by the FtsK DNA translocase. Most Xer systems, as XerCD/dif, include two different recombinases. However, some, as the Lactococcus lactis XerS/difSL system, include only one recombinase. We investigated the functional effects of this difference by studying the XerS/difSL system. XerS bound and recombined difSL sites in vitro, both activities displaying asymmetric characteristics. Resolution of chromosome dimers by XerS/difSL required translocation by division septum-borne FtsK. The translocase domain of L. lactis FtsK supported recombination by XerCD/dif, just as E. coli FtsK supports recombination by XerS/difSL. Thus, the FtsK-dependent coupling of chromosome segregation with cell division extends to non-rod-shaped bacteria and outside the phylum Proteobacteria. Both the XerCD/dif and XerS/difSL recombination systems require the control activities of the FtsKγ subdomain. However, FtsKγ activates recombination through different mechanisms in these two Xer systems. We show that FtsKγ alone activates XerCD/dif recombination. In contrast, both FtsKγ and the translocation motor are required to activate XerS/difSL recombination. These findings have implications for the mechanisms by which FtsK activates recombination