Association of traumatic events with levels of psychological distress and depressive symptoms in male asylum seekers and refugees resettled in Italy

Background: In recent years there has been a progressive rise in the number of asylum seekers and refugees displaced from their country of origin, with significant social, economic, public health and mental health implications. The aim of this study is to (1) describe the level of psychological distress and frequency of psychiatric disorders in a sample of male asylum seekers and refugees across different ethnic groups resettled in Italy; (2) establish whether the number of traumatic events experienced before, during and after the migration process is associated with level of psychological distress and depressive symptoms. Methods: In two large Italian catchment areas, over a period of 1 year a consecutive series of male asylum seekers and refugees, aged 18 or above and included in the Italian protection system, were screened for psychological distress and psychiatric disorders using validated questionnaires. Results: During the study period, 252 male asylum seekers or refugees were recruited. More than one-third of the participants (34.5%) showed clinically relevant psychological distress, and one-fourth (22.2%), met the criteria for a psychiatric diagnosis, mainly Post Traumatic Stress Disorder and depressive disorders. The number of traumatic events turned out to be a risk factor for both clinically relevant psychological distress and depressive disorders. Receiving good social support emerged as a protective factor, while migrants with unclear status were at higher risk of psychological distress than those holding or awaiting a permission. Discussion: In an unselected sample of male asylum seekers and refugees, after around 1 year of resettlement in Italy, the frequency of psychological distress and psychiatric disorders was substantial and clinically relevant. The association between traumatic events, especially post-migration problems, and mental health conditions suggests the need of developing services to assist refugees and asylum seekers to address the multi-faceted problems they experience, such as social support in host country, legal problems concerning permit status and asylum procedure, and family reunification, as well as addressing trauma and mental health issues

Severe and Persistent Depletion of Circulating Plasmacytoid Dendritic Cells in Patients with 2009 Pandemic H1N1 Infection

Background: Dysregulation of host immune responses plays a critical role in the pathogenesis of severe 2009 pandemic H1N1 infection. Whether H1N1 virus could escape innate immune defense in vivo remains to be investigated. The aim of this study was to evaluate the pattern of innate immune response during human 2009 H1N1 infection. We performed the enumeration of circulating myeloid dendritic cells (mDC) and plasmacytoid DC (pDC) in blood from patients with H1N1 pneumonia shortly after the onset of symptoms and during follow-up at different intervals of time. The analysis of CD4 and CD8 count, CD38 T-cell activation marker and serum cytokine/chemokine plasma levels was also done. Methodology/Principal Findings: Blood samples were collected from 13 hospitalized patients with confirmed H1N1-related pneumonia at time of admission and at weeks 1, 4, and 16 of follow-up. 13 healthy donors were enrolled as controls. In the acute phase of the disease, H1N1-infected patients exhibited a significant depletion in both circulating pDC and mDC in conjunction with a decrease of CD4 and CD8 T cell count. In addition, we found plasmatic hyperproduction of IP-10 and RANTES, whereas increase in T-cell immune activation was found at all time points. When we assessed the changes in DC count over time, we observed a progressive normalization of mDC number. On the contrary, H1N1-infected patients did not achieve a complete recovery of pDC count as values remained lower than healthy controls even after 16 weeks of follow-up. Conclusions: H1N1 disease is associated with a profound depletion of DC subsets. The persistence of pDC deficit for several weeks after disease recovery could be due to H1N1 virus itself or to a preexisting impairment of innate immunity

Nuevas socialidades, y configuraciones de mundo entorno a las redes sociales digitales. Un estudio situado con jóvenes estudiantes

Ulla, Cecilia. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Emanuelli, Paulina B. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ardini, Claudia. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Vargas, Laura. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ortúzar, Isabel. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Redolfi, Cecilia. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Masera, Marta. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Trimano, Luciana. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Zárate, Zulma. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Calderón, Angelina. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Rey, Mariana. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ferrari, Mariana. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Massetti, Carolina. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Manzanares, Belén. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Altieri, Ana Clara. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Moroni, Luciano. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Valdez, Lucas. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Moreno, Soledad. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ulla, Cecilia. Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Vivimos en la denominada revolución virtual donde los procesos comunicativos son mediados por tecnologías digitales. En una nueva forma de intercambio simbólico y construcción de relaciones interpersonales dentro de un grupo específico, la juventud, que va a constituir un nuevo mundo compartido y construido por sus miembros en base a las representaciones sociales e imaginarios colectivos, con fuerte implicaciones intersubjetivas. Así las Tribus Urbanas a modo de expresión y alejamiento de la monotonía de lo institucionalizado, van a ser representantes de un nuevo espíritu del tiempo que se puede llamar con el nombre de socialidad. En éste marco nos interrogamos: ¿Qué cosmovisión tienen los jóvenes de ingresantes a primer año de la Escuela de Ciencias de la Información, del espacio, tiempo, territorio, relaciones, emociones, del trabajo y los Valores hegemónicos?Ulla, Cecilia. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Emanuelli, Paulina B. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ardini, Claudia. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Vargas, Laura. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ortúzar, Isabel. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Redolfi, Cecilia. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Masera, Marta. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Trimano, Luciana. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Zárate, Zulma. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Calderón, Angelina. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Rey, Mariana. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ferrari, Mariana. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Massetti, Carolina. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Manzanares, Belén. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Altieri, Ana Clara. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Moroni, Luciano. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Valdez, Lucas. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Moreno, Soledad. (2013). Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Ulla, Cecilia. Universidad Nacional de Córdoba. Escuela de Ciencias de la Información. Argentina.Otras Comunicación y Medio

Evaluation of Triple Whammy Prescriptions After the Implementation of a Drug Safety Algorithm.

BACKGROUND AND OBJECTIVE The term triple whammy (TW) refers to the concomitant use of non-steroidal anti-inflammatory drugs, diuretics, and angiotensin system inhibitors; this combination significantly increases the risk of acute kidney injury (AKI). To prevent this serious complication, we developed an electronic algorithm that detects TW prescriptions in patients with additional risk factors such as old age and impaired kidney function. The algorithm alerts a clinical pharmacist who then evaluates and forwards the alert to the prescribing physician. METHODS We evaluated the performance of this algorithm in a retrospective observational study of clinical data from all adult patients admitted to the Cantonal Hospital of Aarau in Switzerland in 2021. We identified all patients who received a TW prescription, had a TW alert, or developed AKI during TW therapy. Algorithm performance was evaluated by calculating the sensitivity and specificity as a primary endpoint and determining the acceptance rate among clinical pharmacists and physicians as a secondary endpoint. RESULTS Among 21,332 hospitalized patients, 290 patients had a TW prescription, of which 12 patients experienced AKI. Overall, 216 patients were detected by the alert algorithm, including 11 of 12 patients with AKI; the algorithm sensitivity is 88.3% with a specificity of 99.7%. Physician acceptance was high (77.7%), but clinical pharmacists were reluctant to forward the alerts to prescribers in some cases. CONCLUSION The TW algorithm is highly sensitive and specific in identifying patients with TW therapy at risk for AKI. The algorithm may help to prevent AKI in TW patients in the future

"I 20 comandamenti"

Consigli e indicazioni semi-serie su come affrontare un corso online per la prima volta, raccontate da alcuni partecipanti all’edizione online del corso di Tecnologie Didattiche, organizzato nell’ambito della SSIS Liguria

Violenza intrafamiliare: un’indagine casistica sulle sentenze del Tribunale di Terni dal 1985 al 2005

This work, using as source of data the Registries of Court’s Judgement of Terni from 1985 to 200 is to be considered as a study based on the observation of domestic violence in the district of Terni in the last twenty years and as a starting point to improve a consideration on a social problem on the increase but still hidden, and on the need to get ready with suitable secondary prevention’s plan on behalf of Social Control’s Office and Institutions. Results allow for outlining a gross portrayal of aggressors and victims of such a crime, offering instruments to identify those subjects who are considered to be prospective authors or victims of such a violence; moreover data allow to sketch out the main features of the crime itself, thus allowing for a comparison with the national position, to estimate the need to improve specific and autonomous prevention and intervention plans at regional level.L’indagine presentata, utilizzando come fonte di notizie i Registri delle Sentenze del Tribunale di Terni relativi al periodo compreso fra il 1985 ed il 2005, si configura come uno studio epidemiologico-osservazionale delle violenze intrafamiliari nel territorio ternano negli ultimi venti anni e vuole essere di spunto per una riflessione su un problema sociale sempre più dilagante ma ancora estremamente nascosto, nonché sulla necessità dell’attuazione di un più appropriato piano di prevenzione secondaria da parte delle Agenzie di Controllo Sociale e delle Istituzioni. I risultati ottenuti dalla casistica esaminata ci hanno permesso di delineare un generico profilo sia degli autori che delle vittime del reato, offrendo di conseguenza gli strumenti per individuare i soggetti più a rischio; è stato inoltre possibile definire le principali caratteristiche del delitto per permettere un confronto con il quadro definito a livello nazionale, allo scopo di valutare la necessità o meno di piani di prevenzione e di intervento territoriali mirati e autonomi

A Seven-Year Prospective Study on Spondylodiscitis: Epidemiological and Microbiological Features

Background: The aim of this paper was to enlarge the available knowledge on clinical and etiological aspects of patients affected by spondylodiscitis. Patients and Methods: All patients with spondylodiscitis admitted between January 2001 and December 2007 at the 1,300-bed University Hospital "Policlinic Umberto I" of Rome, Italy, were followed. Demographic characteristics, underlying diseases, invasive procedures, imaging studies, isolated microorganisms, treatment, complications, and outcome were recorded. Results: Eighty-one patients of mean age 57.7 +/- 14.7 years with lumbosacral (72.8%), thoracic (14.8%), and cervical tract (12.3%) site of infection were included, of which 38 developed community-acquired (CA) spondylodiscitis and 43 developed hospital-acquired (HA) spondylodiscitis. Underlying disease was present in 49.4% of patients. HA spondylodiscitis was diagnosed earlier (46.8 +/- 49.7 days) than CA spondylodiscitis (65.0 +/- 55.4 days) (P = 60 days (RR 2.65; 95% CI 0.92-7.59; P < 0.05). Conclusions: Infectious spondylodiscitis affects most frequently the elderly population, who are more exposed to healthcare contacts. Consequently, the infection etiology includes a growing proportion of multi-resistant bacteria and fungi

Virtual reality in multiple sclerosis - A systematic review

Introduction: Multiple sclerosis (MS) is an inflammatory disease in which the insulating cover of nerve cells in the brain and spinal cord are damaged. The methods used for motor rehabilitation of patients with neurological problems require the performance of several rehabilitation exercises. Recently, studies related to the use of video game consoles have proliferated in the field of motor rehabilitation. Virtual reality (VR) has been proposed as a potentially useful tool for motoring assessment and rehabilitation. Objective: The purpose of this study was to investigate the results shown in previous studies on "Multiple Sclerosis" and "Virtual Reality". Method: A bibliographic review was performed without time limitations. The research was carried out using PubMed and BVS databases. Considering keywords, we included articles that showed the terms "Multiple Sclerosis" and "Virtual Reality". The review was according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines Results: The initial search yielded 41 articles. After the duplicates were removed, two authors independently evaluated the title and abstract of each of the articles with the study inclusion criteria. From these, 31 articles were excluded based on the title and abstract. Finally, 10 articles were isolated that met the inclusion criteria. Conclusion: VR represents a motivational and effective alternative to traditional motor rehabilitation for MS patients. The results showed that VR programs could be an effective method of patients with MS rehabilitation in multiple cognitive and / or motor deficits. Additional research is needed to support the rehabilitation protocols with VR and increase the effects of treatment. (C) 2016 Elsevier B.V. All rights reserved.Univ Sao Paulo, Fac Med, Postgrad Program Rehabil Sci, Rua Cipotanea 51, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Paulista Sch Med, Postgrad Program Cardiol, Sao Paulo, SP, BrazilFac Med ABC, Dept Morphol & Physiol, Santo Andre, SP, BrazilUniv Fed Sao Paulo, Paulista Sch Med, Postgrad Program Cardiol, Sao Paulo, SP, BrazilWeb of Scienc