Intra- and Inter-database Study for Arabic, English, and German Databases:Do Conventional Speech Features Detect Voice Pathology?

A large population around the world has voice complications. Various approaches for subjective and objective evaluations have been suggested in the literature. The subjective approach strongly depends on the experience and area of expertise of a clinician, and human error cannot be neglected. On the other hand, the objective or automatic approach is noninvasive. Automatic developed systems can provide complementary information that may be helpful for a clinician in the early screening of a voice disorder. At the same time, automatic systems can be deployed in remote areas where a general practitioner can use them and may refer the patient to a specialist to avoid complications that may be life threatening. Many automatic systems for disorder detection have been developed by applying different types of conventional speech features such as the linear prediction coefficients, linear prediction cepstral coefficients, and Mel-frequency cepstral coefficients (MFCCs). This study aims to ascertain whether conventional speech features detect voice pathology reliably, and whether they can be correlated with voice quality. To investigate this, an automatic detection system based on MFCC was developed, and three different voice disorder databases were used in this study. The experimental results suggest that the accuracy of the MFCC-based system varies from database to database. The detection rate for the intra-database ranges from 72% to 95%, and that for the inter-database is from 47% to 82%. The results conclude that conventional speech features are not correlated with voice, and hence are not reliable in pathology detection

An intelligent healthcare system for detection and classification to discriminate vocal fold disorders

The growing population of senior citizens around the world will appear as a big challenge in the future and they will engage a significant portion of the healthcare facilities. Therefore, it is necessary to develop intelligent healthcare systems so that they can be deployed in smart homes and cities for remote diagnosis. To overcome the problem, an intelligent healthcare system is proposed in this study. The proposed intelligent system is based on the human auditory mechanism and capable of detection and classification of various types of the vocal fold disorders. In the proposed system, critical bandwidth phenomena by using the bandpass filters spaced over Bark scale is implemented to simulate the human auditory mechanism. Therefore, the system acts like an expert clinician who can evaluate the voice of a patient by auditory perception. The experimental results show that the proposed system can detect the pathology with an accuracy of 99.72%. Moreover, the classification accuracy for vocal fold polyp, keratosis, vocal fold paralysis, vocal fold nodules, and adductor spasmodic dysphonia is 97.54%, 99.08%, 96.75%, 98.65%, 95.83%, and 95.83%, respectively. In addition, an experiment for paralysis versus all other disorders is also conducted, and an accuracy of 99.13% is achieved. The results show that the proposed system is accurate and reliable in vocal fold disorder assessment and can be deployed successfully for remote diagnosis. Moreover, the performance of the proposed system is better as compared to existing disorder assessment systems

A Practical Approach: Design and Implementation of a Healthcare Software for Screening of Dysphonic Patients

Risk management in the development of medical software and devices is one of the most crucial processes in ensuring accurate diagnoses and treatment of disease. The consequences of wrong decisions that happen in our daily life might be unembellished. However, wrong decisions in healthcare based on unreliable evidence due to erroneous software could result in loss of life. Dysphonic patients suffering from various vocal fold disorders might have a threat of life due to inaccurate diagnosis. Some voice disorders, such as keratosis, are precancerous, and can become cancerous in cases that involve inaccurate diagnosis due to software failure. The objective of this paper is to design and implement a healthcare software for the detection of voice disorders in nonperiodic speech signals. Occurrences of potential risks during the design and development of the proposed software are taken into account to avoid failure. The software is implemented by applying the local binary pattern (LBP) operator on the textures of nonperiodic signals. The textures are obtained through the recurrence plot. The LBP operator computes the histograms for normal persons and dysphonic patients, and these histograms are used with the support vector machine for the automatic classification of dysphonic patients. The software is evaluated and tested by using the Massachusetts Eye and Ear Infirmary voice disorder database. The success rate of the proposed healthcare system is 97.73% ± 1.2, and the area under the receiver operating characteristic curve is 0.98 ± 0. The performance of the proposed healthcare system is much better than the existing commercial software used for screening dysphonic patients

Chaos-based robust method of zero-watermarking for medical signals

The growing use of wireless health data transmission via Internet of Things is significantly beneficial to the healthcare industry for optimal usage of health-related facilities. However, at the same time, the use raises concern of privacy protection. Health-related data are private and should be suitably protected. Several pathologies, such as vocal fold disorders, indicate high risks of prevalence in individuals with voice-related occupations, such as teachers, singers, and lawyers. Approximately, one-third of the world population suffers from the voice-related problems during the life span and unauthorized access to their data can create unavoidable circumstances in their personal and professional lives. In this study, a zero-watermarking method is proposed and implemented to protect the identity of patients who suffer from vocal fold disorders. In the proposed method, an image for a patient's identity is generated and inserted into secret keys instead of a host medical signal. Consequently, imperceptibility is naturally achieved. The locations for the insertion of the watermark are determined by a computation of local binary patterns from the time–frequency spectrum. The spectrum is calculated for low frequencies such that it may not be affected by noise attacks. The experimental results suggest that the proposed method has good performance and robustness against noise, and it is reliable in the recovery of an individual's identity

Development of the Arabic Voice Pathology Database and Its Evaluation by Using Speech Features and Machine Learning Algorithms

A voice disorder database is an essential element in doing research on automatic voice disorder detection and classification. Ethnicity affects the voice characteristics of a person, and so it is necessary to develop a database by collecting the voice samples of the targeted ethnic group. This will enhance the chances of arriving at a global solution for the accurate and reliable diagnosis of voice disorders by understanding the characteristics of a local group. Motivated by such idea, an Arabic voice pathology database (AVPD) is designed and developed in this study by recording three vowels, running speech, and isolated words. For each recorded samples, the perceptual severity is also provided which is a unique aspect of the AVPD. During the development of the AVPD, the shortcomings of different voice disorder databases were identified so that they could be avoided in the AVPD. In addition, the AVPD is evaluated by using six different types of speech features and four types of machine learning algorithms. The results of detection and classification of voice disorders obtained with the sustained vowel and the running speech are also compared with the results of an English-language disorder database, the Massachusetts Eye and Ear Infirmary (MEEI) database

Protection of Records and Data Authentication based on Secret Shares and Watermarking

The rapid growth in communication technology facilitates the health industry in many aspects from transmission of sensor’s data to real-time diagnosis using cloud-based frameworks. However, the secure transmission of data and its authenticity become a challenging task, especially, for health-related applications. The medical information must be accessible to only the relevant healthcare staff to avoid any unfortunate circumstances for the patient as well as for the healthcare providers. Therefore, a method to protect the identity of a patient and authentication of transmitted data is proposed in this study. The proposed method provides dual protection. First, it encrypts the identity using Shamir’s secret sharing scheme without the increase in dimension of the original identity. Second, the identity is watermarked using zero-watermarking to avoid any distortion into the host signal. The experimental results show that the proposed method encrypts, embeds and extracts identities reliably. Moreover, in case of malicious attack, the method distorts the embedded identity which provides a clear indication of fabrication. An automatic disorder detection system using Mel-frequency cepstral coefficients and Gaussian mixture model is also implemented which concludes that malicious attacks greatly impact on the accurate diagnosis of disorders

Edge-centric multimodal authentication system using encrypted biometric templates

Data security, complete system control, and missed storage and computing opportunities in personal portable devices are some of the major limitations of the centralized cloud environment. Among these limitations, security is a prime concern due to potential unauthorized access to private data. Biometrics, in particular, is considered sensitive data, and its usage is subject to the privacy protection law. To address this issue, a multimodal authentication system using encrypted biometrics for the edge-centric cloud environment is proposed in this study. Personal portable devices are utilized for encrypting biometrics in the proposed system, which optimizes the use of resources and tackles another limitation of the cloud environment. Biometrics is encrypted using a new method. In the proposed system, the edges transmit the encrypted speech and face for processing in the cloud. The cloud then decrypts the biometrics and performs authentication to confirm the identity of an individual. The model for speech authentication is based on two types of features, namely, Mel-frequency cepstral coefficients and perceptual linear prediction coefficients. The model for face authentication is implemented by determining the eigenfaces. The final decision about the identity of a user is based on majority voting. Experimental results show that the new encryption method can reliably hide the identity of an individual and accurately decrypt the biometrics, which is vital for errorless authentication

A zero-watermarking algorithm for privacy protection in biomedical signals

Confidentiality of health information is indispensable to protect privacy of an individual. However, recent advances in electronic healthcare systems allow transmission of sensitive information through the Internet, which is prone to various vulnerabilities, attacks and may leads to unauthorized disclosure. Such situations may not only create adverse effects for individuals but may also cause severe consequences such as hefty regulatory fines, bad publicity, legal fees, and forensics. To avoid such predicaments, a privacy protected healthcare system is proposed in this study that protects the identity of an individual as well as detects vocal fold disorders. The privacy of the developed healthcare system is based on the proposed zero-watermarking algorithm, which embeds a watermark in a secret key instead of the signals to avoid the distortion in an audio sample. The identity is protected by the generation of its secret shares through visual cryptography. The generated shares are embedded by finding the patterns into the audio with the application of one-dimensional local binary pattern. The proposed zero-watermarking algorithm is evaluated by using audio samples taken from the Massachusetts Eye and Ear Infirmary voice disorder database. Experimental results demonstrate that the proposed algorithm achieves imperceptibility and is reliable in its extraction of identity. In addition, the proposed algorithm does not affect the results of disorder detection and it is robust against noise attacks of various signal-to-noise ratios

Intra operative, post operative complications and visual outcome in cases of post uveitic cataracts.

INTRODUCTION: Cataract surgery in a patient with uveitis is more complex than senile cataract extraction, because it involves multiple considerations related to the cause of uveitis, prospects of visual rehabilitation, appropriate surgical timing, and technique, the type and material of intra ocular lens used. Establishing the diagnosis, thorough ocular examination, careful patient selection and meticulous control of perioperative inflammation are key elements to a successful visual outcome. AIM OF THE STUDY: 1. To assess intra operative and post operative complications encountered during surgery for uveitic cataract. 2. To assess the factors which affect the visual outcome. MATERIALS AND METHODS: The study was done in Regional Institute of Ophthalmology and Government Ophthalmic Hospital, Egmore, Chennai from August 2005 to October 2007. The patients who attended the out patient and uvea clinic were included for the study. A total of 60 patients were taken up for the study. A detailed history and a complete ophthalmic examination was done. Inclusion criteria : 1. Patients with chronic uveitis and complicated cataract. 2. A quite eye (without inflammation) for atleast 3 months. Exclusion criteria : 1. Complicated cataract due to causes other than uveitis. 2. Patients with posterior segment pathology (by Bscan). RESULTS: The visual acuity after 6 wks ranged from 6/6 to 6/18 in 34 patients, 6/24 to 6/60 in 26 patients. The most common cause for decrease in vision was posterior capsular opacification. CONCLUSION: Cataract development is a very common occurrence in any form of anterior and intermediate uveitis, because of chronic intraocular inflammation, frequent relapses and long term use of corticosteroids. The reported incidence of cataract in uveitic patients is about 50% in juvenile rheumatoid arthritis and upto 75% in chronic anterior uveitis