Magnetic Discontinuities in Magnetohydrodynamic Turbulence and in the Solar Wind

Recent measurements of solar wind turbulence report the presence of intermittent, exponentially distributed angular discontinuities in the magnetic field. In this Letter, we study whether such discontinuities can be produced by magnetohydrodynamic (MHD) turbulence. We detect the discontinuities by measuring the fluctuations of the magnetic field direction, Delta theta, across fixed spatial increments Delta x in direct numerical simulations of MHD turbulence with an imposed uniform guide field B_0. A large region of the probability density function (pdf) for Delta theta is found to follow an exponential decay, proportional to exp(-Delta theta/theta_*), with characteristic angle theta_* ~ (14 deg) (b_rms/B_0)^0.65 for a broad range of guide-field strengths. We find that discontinuities observed in the solar wind can be reproduced by MHD turbulence with reasonable ratios of b_rms/B_0. We also observe an excess of small angular discontinuities when Delta x becomes small, possibly indicating an increasing statistical significance of dissipation-scale structures. The structure of the pdf in this case closely resembles the two-population pdf seen in the solar wind. We thus propose that strong discontinuities are associated with inertial-range MHD turbulence, while weak discontinuities emerge from near-dissipation-range turbulence. In addition, we find that the structure functions of the magnetic field direction exhibit anomalous scaling exponents, which indicates the existence of intermittent structures.Comment: To appear in Physical Review Letter

Collaborative public procurement: Institutional explanations of legitimised resistance

This paper reports on the barriers to regional collaborative procurement developed from an action research study of five UK public authorities in the emergency services sector. Despite political pressure to procure collaboratively, strategic avoidance responses of institutional logics and symbolic tick boxing legitimise stakeholder resistance to isomorphic forces and entrench operational barriers. The prevailing institutional logics are that regional collaborative procurement is unsuitable and risky, derived from procurement's lack of status and the emotive nature of the emergency services. Symbolic tick boxing is seen through collaboration that is limited to high profile spend categories, enabling organisations to demonstrate compliance while simultaneously retaining local decision-making for less visible, but larger areas of spend. The findings expose choice mechanisms in public procurement by exploring tensions arising from collaborative procurement strategies within, and between, organisations. Multiple stakeholders' perspectives add to current thinking on how organisations create institutional logics to avoid institutional pressure to procure collaboratively and how stakeholders legitimise their actions

Solitary dynamo waves

Abstract Long dynamo waves are a characteristic feature of interface dynamo models with spatially localized α and Ω effects. The evolution of such waves is described by the modified Korteweg-de Vries equation. Solutions to this equation take the form of solitary waves, breathers, and snoidal and cnoidal waves, and represent nonlinear waves of magnetic activity that migrate towards the equator, as observed on the Sun. Averaging techniques extend the theory to longer times and relate the amplitude of these waves to the dynamo number

The relationship between psychological distress and adolescent polydrug use

Polydrug use is relatively common among adolescents. Psychological distress is associated with the use of specific drugs, and may be uniquely associated with polydrug use. The purpose of this study was to test the association of psychological distress with polydrug use using a large adolescent sample. The sample consisted of 10,273 students aged 12-17 years from the State of Victoria, Australia. Participants completed frequency measures of tobacco, alcohol, cannabis, inhalant, and other drug use in the past 30 days, and psychological distress. Control variables included age, gender, family socioeconomic status, school suspensions, academic failure, cultural background, and peer drug use. Drug-use classes were derived using latent-class analysis, then the association of psychological distress and controls with drug-use classes was modeled using multinomial ordinal regression. There were 3 distinct classes of drug use: no drug use (47.7%), mainly alcohol use (44.1%), and polydrug use (8.2%). Independent of all controls, psychological distress was higher in polydrug users and alcohol users, relative to nondrug users, and polydrug users reported more psychological distress than alcohol users. Psychological distress was most characteristic of polydrug users, and targeted prevention outcomes may be enhanced by a collateral focus on polydrug use and depression and/or anxiety

Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer

The RUNX1 transcription factor is widely recognised for its tumour suppressor effects in leukaemia. Recently a putative link to breast cancer has started to emerge, however the function of RUNX1 in breast cancer is still unknown. To investigate if RUNX1 expression was important to clinical outcome in primary breast tumours a tissue microarray (TMA) containing biopsies from 483 patients with primary operable invasive ductal breast cancer was stained by immunohistochemistry. RUNX1 was associated with progesterone receptor (PR)-positive tumours (P<0.05), more tumour CD4+(P<0.05) and CD8+(P<0.01) T-lymphocytic infiltrate, increased tumour CD138+plasma cell (P<0.01) and more CD68+macrophage infiltrate (P<0.001). RUNX1 expression did not influence outcome of oestrogen receptor (ER)-positive or HER2-positive disease, however on univariate analysis a high RUNX1 protein was significantly associated with poorer cancer-specific survival in patients with ER-negative (P<0.05) and with triple negative (TN) invasive breast cancer (P<0.05). Furthermore, multivariate Cox regression analysis of cancer-specific survival showed a trend towards significance in ER-negative patients (P<0.1) and was significant in triple negative patients (P<0.05). Of relevance, triple negative breast cancer currently lacks good biomarkers and patients with this subtype do not benefit from the option of targeted therapy unlike patients with ER-positive or HER2-positive disease. Using multivariate analysis RUNX1 was identified as an independent prognostic marker in the triple negative subgroup. Overall, our study identifies RUNX1 as a new prognostic indicator correlating with poor prognosis specifically in the triple negative subtype of human breast cancer

Limits of object persistence:young infants perceive continuity of vertical and horizontal trajectories, but not 45-degree oblique trajectories

Previous research indicated that 4-month-old infants perceive continuity of objects moving on horizontal trajectories but appear to have difficulty processing occlusion events involving oblique trajectories. However, because perception of continuity of vertical trajectories has not been tested, it is uncertain whether this indicates a specific deficit for oblique trajectories or a specific advantage for horizontal trajectories. We evaluated the contribution of trajectory orientation and the form of occlusion in three experiments with 144 4-month-olds. Infants perceived continuity of horizontal and vertical trajectories under all conditions presented. However, they did not perceive continuity of an oblique (45˚) trajectory under any condition. Thus 4-month-olds appear unable to process continuity of a 45˚ trajectory. In a fourth experiment with 48 6- and 8-month-old infants, we demonstrated that by 6 months infants' difficulty with oblique trajectories is overcome. We suggest that young infants’ difficulty with oblique trajectories likely relates to immature eye movement control