A Multidimensional Model: Assessing Space Needs in Healthcare Facilities in Response to COVID-19

The assessment of space needs in healthcare facilities has become a growing issue as a result of COVID-19 and its impact on the US healthcare system. Healthcare leaders and facility decision makers have a unique opportunity to evaluate space needs by rightsizing and adapting to reflect current and future pandemic-related events. This paper aims to support the decision-making process by presenting an integrative developmental model of a conceptual framework conceived through a synthesis of the existing literature. Three major dimensions have been identified in the Findings which serve as a foundational guide to addressing space needs: processes, people and the built environment. Processes: highlights operational-enablement activities and the need to redefine tasks across the spectrum of on-site to remote; the potential to reengineer directional flow of people through facilities and how people arrive and wait; infection and prevention controls (IPC) through proximity parameters and cleaning protocols. People: considers patient mix through evaluating degree of patient segmentation and desired utilization levels for healthcare services; worker engagement and how spaces will encourage productivity, collaboration and flexibility; visitor management through enhanced communication efforts and outlining accessibility and tracking needs. Built environment explores elements of space planning including agile design, spatial configuration and touchless functionality; the impact of technology through again, touchless functions, level of infrastructure and changing privacy and security implications; facility components through the intensified role of mechanical systems, signage to support major processes and reworking of furniture, fixtures and equipment (FF&E)

LaRC Aerothermodynamic Ground Tests in Support of BOLT Flight Experiment

A review is provided of recent aerothermodynamic ground-test contributions by NASA Langley Research Center (LaRC) to the BOLT flight test program. Several test entries into the Langley Aerothermodynamic Laboratory 20-Inch Mach 6 Air Tunnel are discussed. These entries were intended to support the development and design of flight hardware and instrumentation. Some trends and observations from these entries are provided. Also, a comparison of two different global heat transfer test techniques is included and discussed

Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer

The RUNX1 transcription factor is widely recognised for its tumour suppressor effects in leukaemia. Recently a putative link to breast cancer has started to emerge, however the function of RUNX1 in breast cancer is still unknown. To investigate if RUNX1 expression was important to clinical outcome in primary breast tumours a tissue microarray (TMA) containing biopsies from 483 patients with primary operable invasive ductal breast cancer was stained by immunohistochemistry. RUNX1 was associated with progesterone receptor (PR)-positive tumours (P<0.05), more tumour CD4+(P<0.05) and CD8+(P<0.01) T-lymphocytic infiltrate, increased tumour CD138+plasma cell (P<0.01) and more CD68+macrophage infiltrate (P<0.001). RUNX1 expression did not influence outcome of oestrogen receptor (ER)-positive or HER2-positive disease, however on univariate analysis a high RUNX1 protein was significantly associated with poorer cancer-specific survival in patients with ER-negative (P<0.05) and with triple negative (TN) invasive breast cancer (P<0.05). Furthermore, multivariate Cox regression analysis of cancer-specific survival showed a trend towards significance in ER-negative patients (P<0.1) and was significant in triple negative patients (P<0.05). Of relevance, triple negative breast cancer currently lacks good biomarkers and patients with this subtype do not benefit from the option of targeted therapy unlike patients with ER-positive or HER2-positive disease. Using multivariate analysis RUNX1 was identified as an independent prognostic marker in the triple negative subgroup. Overall, our study identifies RUNX1 as a new prognostic indicator correlating with poor prognosis specifically in the triple negative subtype of human breast cancer

Connectivity Series at RIT- Developing & Delivering an Effective Professional Development Workshop Series for Women Faculty in STEM

In science, technology, engineering and math (STEM) disciplines within the United States; women faculty are underrepresented within many disciplines including engineering, computer science, and physics. At a large private university, RIT, the ADVANCE institutional transformation project (supported by NSF Award No. 1209115), referred to as Advance RIT, aims to increase the representation and advancement of women STEM faculty (which includes social and behavioral sciences, SBS) by removing barriers to resources that support career success and by creating new interventions and resources. This paper reports on the design, delivery and evaluation of a professional development workshop series, called the Connectivity Series, which is a vital initiative within this large-scale, multi-year, strategic institutional transformation project. The workshop series consists of programs to promote the recruitment, retention, and advancement of women faculty. The project team developed workshop themes based upon the results of a faculty climate survey and a literature review as part of a previously conducted NSF ADVANCE funded self-study (0811076). Project researchers created the Connectivity Series for all tenure-track women faculty on campus as well as targeted workshops for women of color and deaf and hard of hearing women faculty. All disciplines represented within the university (STEM and non-STEM) have been identified as the target audience for workshop offerings due to the high prevalence of STEM disciplines within the university. Program assessment and evaluation results are presented. In addition, a sustainability plan is outlined for continuation of these targeted workshops beyond the five-year grant funding period

Surveilling the web, mobile, and language accessibility of Communication’s digital presence within institutions of higher education globally

This study aims to understand the general web accessibility of digital information networks which may serve as barriers for access to the global discipline of Communication through institutional and departmental websites, specifically for persons with disabilities and those with limited English proficiency (LEP). Our exploratory content analysis relies on computer-aided software to systematically analyze the departmental home pages of websites of institutional members of the International Communication Association (ICA), N = 77, representing 26 countries, globally. Findings from this study help us to: (1) better understand the general web, language, and mobile accessibility of discipline-related online information; (2) identify strengths and opportunities for improvement; and, (3) to reflect upon the anticipated barriers impacting persons with disabilities when accessing higher education information online

Longitudinal Assessment of Dementia Measures in Down Syndrome

Introduction: Early detection of dementia symptoms is critical in Down syndrome (DS) but complicated by clinical assessment barriers. The current study aimed to characterize cognitive and behavioral impairment using longitudinal trajectories comparing several measures of cognitive and behavioral functioning. Methods: Measures included global cognitive status (Severe Impairment Battery [SIB]), motor praxis (Brief Praxis Test [BPT]), and clinical dementia informant ratings (Dementia Questionnaire for People with Learning Disabilities [DLD]). One-year reliability was assessed using a two-way mixed effect, consistency, single measurement intraclass correlation among non-demented participants. Longitudinal assessment of SIB, BPT, and DLD was completed using linear mixed effect models. Results: One‐year reliability (n = 52; 21 male) was moderate for DLD (0.69 to 0.75) and good for SIB (0.87) and BPT (0.80). Longitudinal analysis (n = 72) revealed significant age by diagnosis interactions for SIB (F(2, 115.02) = 6.06, P = .003), BPT (F(2, 85.59) = 4.56, P = .013), and DLD (F(2, 103.56) = 4.48, P = .014). SIB progression (PR) had a faster decline in performance versus no‐dementia (ND) (t(159) = −2.87; P = .013). Dementia had a faster decline in BPT performance versus ND (t(112) = −2.46; P = .041). PR showed quickly progressing scores compared to ND (t(128) = −2.86; P = .014). Discussion: Current measures demonstrated moderate to good reliability. Longitudinal analysis revealed that SIB, BPT, and DLD changed with age depending on diagnostic progression; no change rates were dependent on baseline cognition, indicating usefulness across a variety of severity levels in DS

Using mixed methods for analysing culture : The Cultural Capital and Social Exclusion project

This paper discusses the use of material generated in a mixed method investigation into cultural tastes and practices, conducted in Britain from 2003 to 2006, which employed a survey, focus groups and household interviews. The study analysed the patterning of cultural life across a number of fields, enhancing the empirical and methodological template provided by Bourdieu’s Distinction. Here we discuss criticisms of Bourdieu emerging from subsequent studies of class, culture and taste, outline the arguments related to the use of mixed methods and present illustrative results from the analysis of these different types of data. We discuss how the combination of quantitative and qualitative methods informed our analysis of cultural life in contemporary Britain. No single method was able to shed light on all aspects of our inquiry, lending support to the view that mixing methods is the most productive strategy for the investigation of complex social phenomena