30 research outputs found
SUSTAINING COMPETITIVE ADVANTAGE IN THE OIL PALM INDUSTRY: SWOT ANALYSIS OF IOI CORPORATION
IOI Corporation, or commonly referred to as IOI, is one of Malaysia's home grown business conglomerates which started off from humble beginnings in industrial gas manufacturing. Today IOI Group is a global organization with over 150,000 hectares of plantations where 98% are planted with oil palm; 12 palm oil mills across Malaysia; three CPO refineries with total capacity of 1.8 million MT/yr located in Peninsular and East Malaysia, and Rotterdam in the Netherlands; the largest oleochemical plants in Asia; and specialty fats plants across the world in the Netherlands, the United States, Egypt, Canada, and Malaysia (source: IOI Annual Report 2009).The Group’s plantation business strong growth in a short span of 24 years since 1983 was achieved through acquisitions and distinctive plantation management practices which emphasizes on continuous improvements in yields and cost efficiencies. As a major player in the oil palm industry, which is the third biggest contributor to the Malaysian economy (,Economic Report 2007/2008), IOI corporation faces many challenges to sustain its competitiveness. What strategic moves must IOI take to remain tops in this oil palm industry? This paper seeks to provide a perspective on how IOI Corporation can sustain its competitiveness by undertaking a SWOT Analysis the corporation. A diagnosis of the corporation is made after the SWOT analysisCompetitiveness, SWOT Anlaysis, Oil palm industry, Case study
Building the Dream Team: Sweet Dreams Turning into Nightmares
The one-on-one session was approaching the third hour and Jenny was feeling a bit weary.She was
into her third month in Action Think Tank (ATT) and what she expected to be a smooth-sailing onboarding into the role of the Director of Research was far off tangent.“It is important for you to take your role seriously as you have agreed to take on the responsibility of a director. While, you may feel the pressure to agree with the CEO, there is this personal accountability, as the director, to be fair across the board. Leadership is always about making the right decision.”The advice from Dr Quek, a researcher at ATT struck at the core of Jenny’s conscience.This was her first role as a director and although she was initially reluctant to take on the post, the CEO and the Director of Administration, a pleasant and convincing lady, managed to make her change her decision to follow her husband to relocate to Bangkok.A week-end marriage, as it was often called, seemed to be an acceptable arrangement. Her career progress would not be thwarted. Besides, the children would continue to have access to high-quality education in a premier international private school in Kuala Lumpur
Vintage wine
The blue-eyed boy of R & D is disillusioned
about his future at a company which prioritizes research.What could be the cause of this disillusionment? Is it a cause for concern
Continuous Use and Extended Use of E-Government Portals
This study aims to investigate the level of user satisfaction with the services provided by e-government portals and to examine the influence of perceived value and virtual community engagement on citizens’ satisfaction and their continuous and extended use intentions. Primary data were collected from 409 users of e-government portals via a questionnaire survey. The findings show that citizens are generally satisfied with the services provided by e-government portals and have positive continuous use and extended use intentions. The actual usage is more prevalent among educational, banking and finance, and taxation related portals. Both perceived value and virtual community engagement relate positively with citizen satisfaction, with the former has a relatively stronger influence. Citizen satisfaction also leads to continuous and extended use intentions. The findings shed lights on dimensions of e-government portals that citizens considered valuable and the importance of the formation of virtual communities in influencing their satisfaction and subsequent use intentions
Consumers Attitude Towards Organic Food
AbstractThe awareness on the harmful effects of chemicals present in food is increasing among the consumers. The trend towards purchasing organic food is growing among people. A study to identify what actually induces consumers to turn towards organic food is important. Some of the prominent motivating factors to purchase organic foods include environmental concern, health concern and lifestyle, product quality and subjective norms. This empirical study is aimed at identifying the purchase intention of consumers towards organic foods. The study predicts the purchase intention of consumers based on the influences of factors like environmental concern, health concern and lifestyle, product quality and subjective norms on the attitude towards organic foods. The results of the study show that quality of products, environmental concern, health concern and lifestyle are the most commonly stated motives for purchasing organic foods
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation of disability. Epidemiological studies have shown that genetic factors are primarily responsible for the substantially increased frequency of the disease seen in the relatives of affected individuals, and systematic attempts to identify linkage in multiplex families have confirmed that variation within the major histocompatibility complex (MHC) exerts the greatest individual effect on risk. Modestly powered genome-wide association studies (GWAS) have enabled more than 20 additional risk loci to be identified and have shown that multiple variants exerting modest individual effects have a key role in disease susceptibility. Most of the genetic architecture underlying susceptibility to the disease remains to be defined and is anticipated to require the analysis of sample sizes that are beyond the numbers currently available to individual research groups. In a collaborative GWAS involving 9,772 cases of European descent collected by 23 research groups working in 15 different countries, we have replicated almost all of the previously suggested associations and identified at least a further 29 novel susceptibility loci. Within the MHC we have refined the identity of the HLA-DRB1 risk alleles and confirmed that variation in the HLA-A gene underlies the independent protective effect attributable to the class I region. Immunologically relevant genes are significantly overrepresented among those mapping close to the identified loci and particularly implicate T-helper-cell differentiation in the pathogenesis of multiple sclerosis
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity.
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike 614 variants, not all approaches showed a conclusive signal of positive selection. Population genetic analysis indicates that 614G increases in frequency relative to 614D in a manner consistent with a selective advantage. We do not find any indication that patients infected with the spike 614G variant have higher COVID-19 mortality or clinical severity, but 614G is associated with higher viral load and younger age of patients. Significant differences in growth and size of 614G phylogenetic clusters indicate a need for continued study of this variant
Finishing the euchromatic sequence of the human genome
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study
Background:
The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England in March, 2021. It has since rapidly become the predominant lineage, owing to high transmissibility. It is suspected that the delta variant is associated with more severe disease than the previously dominant alpha (B.1.1.7) variant. We aimed to characterise the severity of the delta variant compared with the alpha variant by determining the relative risk of hospital attendance outcomes.
Methods:
This cohort study was done among all patients with COVID-19 in England between March 29 and May 23, 2021, who were identified as being infected with either the alpha or delta SARS-CoV-2 variant through whole-genome sequencing. Individual-level data on these patients were linked to routine health-care datasets on vaccination, emergency care attendance, hospital admission, and mortality (data from Public Health England's Second Generation Surveillance System and COVID-19-associated deaths dataset; the National Immunisation Management System; and NHS Digital Secondary Uses Services and Emergency Care Data Set). The risk for hospital admission and emergency care attendance were compared between patients with sequencing-confirmed delta and alpha variants for the whole cohort and by vaccination status subgroups. Stratified Cox regression was used to adjust for age, sex, ethnicity, deprivation, recent international travel, area of residence, calendar week, and vaccination status.
Findings:
Individual-level data on 43 338 COVID-19-positive patients (8682 with the delta variant, 34 656 with the alpha variant; median age 31 years [IQR 17–43]) were included in our analysis. 196 (2·3%) patients with the delta variant versus 764 (2·2%) patients with the alpha variant were admitted to hospital within 14 days after the specimen was taken (adjusted hazard ratio [HR] 2·26 [95% CI 1·32–3·89]). 498 (5·7%) patients with the delta variant versus 1448 (4·2%) patients with the alpha variant were admitted to hospital or attended emergency care within 14 days (adjusted HR 1·45 [1·08–1·95]). Most patients were unvaccinated (32 078 [74·0%] across both groups). The HRs for vaccinated patients with the delta variant versus the alpha variant (adjusted HR for hospital admission 1·94 [95% CI 0·47–8·05] and for hospital admission or emergency care attendance 1·58 [0·69–3·61]) were similar to the HRs for unvaccinated patients (2·32 [1·29–4·16] and 1·43 [1·04–1·97]; p=0·82 for both) but the precision for the vaccinated subgroup was low.
Interpretation:
This large national study found a higher hospital admission or emergency care attendance risk for patients with COVID-19 infected with the delta variant compared with the alpha variant. Results suggest that outbreaks of the delta variant in unvaccinated populations might lead to a greater burden on health-care services than the alpha variant.
Funding:
Medical Research Council; UK Research and Innovation; Department of Health and Social Care; and National Institute for Health Research