Adaptation of the Parent Readiness for Hospital Discharge Scale with Mothers of Preterm Infants Discharged from the Neonatal Intensive Care Unit

Aims and objectives To evaluate the psychometric properties of a new Persian translation of the Readiness for Hospital Discharge Scale. Background Globally, one in 10 newborns are born preterm and many require care in a neonatal intensive care unit (NICU). A primary role of NICU nurses is to assure parents are well prepared to take their newborns home from the hospital. Assessment of parent perception of discharge readiness provides important input into discharge decisions. The availability of reliable and valid instruments tested within the geographical and cultural context is needed for a comprehensive assessment of predischarge readiness, so that parent needs can be identified and the necessary interventions designed and implemented. Design This psychometrics study included a convenience sample of 200 mothers with preterm infants being discharged from the NICU of Shahid Sadoughi Hospital in Yazd, Iran. The original 29‐item version of the Readiness for Hospital Discharge Scale—Parent questionnaire was translated into Persian using the standard forward–backward method. Face, content and construct validity (principal components analysis), and reliability (internal consistency—Cronbach\u27s alpha) were assessed. Methods followed STROBE criteria as applicable (see Appendix S1). Results The content validity index and content validity ratio were both 0.93. Construct validity testing identified 6 factors (mother and infant physical–psychological readiness, expected support, knowledge of future events and care, knowledge of infant personal care, pain and therapeutic interventions). Using Cronbach\u27s alpha coefficient, the reliability of the whole instrument was estimated to be 0.87. Conclusion The Persian Readiness for Hospital Discharge—Parental Form for use with mothers of preterm infants being discharged from an Iranian NICU has acceptable validity and reliability. Relevance to Practice This tool can be used before discharge to determine the needs of mothers and design the necessary measures to improve quality of discharge care

Estudio de la aromaticidad de los compuestos anticancerígenos heterocíclicos mediante el método computacional s-nics

In this study, we have sujessted a theoritical aproach via computing of nucleus-independent chemical shifts (S-NICS) in view point of probes motions in a sphere of de-shielding and shielding spaces of rings of anticancer contain heterocyclic rings. Few research in theoretical of a statistical approach in NMR shielding and nucleus independent chemical shifts for study of anticancer drugs. S-NICS method is an accurate method for estimation the amount of aromaticity in the non-benzene rings such as heterocyclic rings which is a famous for organic chemical compounds as anti-cancer disease. Theoretical of a statistical method of NICS-nucleus independent chemical shift in small distance and are alternate in large distance in the center of heterocyclic rings. In this research, we have explored the statistical approaches through nucleus-independent chemical shifts-SNICS calculations in view point of Bq motions in the center of sphere spaces of heterocyclic rings of some anticancer drugs. The S-NICS method is an accurate computing method for estimation the aromaticity in the non-benzene rings such as heterocyclic rings which are standard molecules in organic anti-cancer compounds. Although NICS values for benzene and naphthalene and so on can be indicated as aromaticity criterion, for other molecules such as heterocyclic rings and their derivatives, S-NICS values are much more accurate compare to NICS index. Hetrocyclic compound with good π stacks are good cacdidate for anticancer medicines.  Precence of Nitrogen, oxygen and sulfur in these compounds make them similar biochemical parts such as nuclice acids and. Aromaticity of heterocyclic ring.   This similarity especially them π stacks give the the ability of interaction with DNAs and RNAs and the heterocyclic compounds.En este estudio, hemos sugerido un enfoque teórico a través de la computación de los cambios químicos independientes del núcleo (S-NICS) en el punto de vista de los movimientos de las sondas en una esfera de espacios de desprotección y protección de anillos de anticancerígenos que contienen anillos heterocíclicos. Pocas investigaciones teóricas sobre un enfoque estadístico en el blindaje de RMN y los cambios químicos independientes del núcleo para el estudio de medicamentos contra el cáncer. El método S-NICS es un método preciso para estimar la cantidad de aromaticidad en los anillos sin benceno, como los anillos heterocíclicos, que es famoso por los compuestos químicos orgánicos como la enfermedad anticancerígena. Teórico de un método estadístico de desplazamiento químico independiente del núcleo NICS a pequeña distancia y se alternan a gran distancia en el centro de los anillos heterocíclicos. En esta investigación, hemos explorado los enfoques estadísticos a través de cálculos de SNICS-cambios químicos independientes del núcleo en el punto de vista de los movimientos Bq en el centro de los espacios de esfera de los anillos heterocíclicos de algunos medicamentos contra el cáncer. El método S-NICS es un método computacional preciso para estimar la aromaticidad en los anillos que no son de benceno, como los anillos heterocíclicos, que son moléculas estándar en los compuestos orgánicos contra el cáncer. Aunque los valores de NICS para benceno y naftaleno, etc., pueden indicarse como criterio de aromaticidad, para otras moléculas como los anillos heterocíclicos y sus derivados, los valores de S-NICS son mucho más precisos en comparación con el índice de NICS. Los compuestos heterocíclicos con buenas pilas π son buenos cacdidatos para medicamentos contra el cáncer. La precedencia de nitrógeno, oxígeno y azufre en estos compuestos los convierte en partes bioquímicas similares, como los ácidos nucleicos y. Aromaticidad del anillo heterocíclico. Esta similitud, especialmente las pilas π, dan la capacidad de interacción con ADN y ARN y los compuestos heterocíclicos

Estudio de la aromaticidad de los compuestos anticancerígenos heterocíclicos mediante el método computacional s-nics

En este estudio, hemos sugerido un enfoque teórico a través de la computación de los cambios químicos independientes del núcleo (S-NICS) en el punto de vista de los movimientos de las sondas en una esfera de espacios de desprotección y protección de anillos de anticancerígenos que contienen anillos heterocíclicos. Pocas investigaciones teóricas sobre un enfoque estadístico en el blindaje de RMN y los cambios químicos independientes del núcleo para el estudio de medicamentos contra el cáncer. El método S-NICS es un método preciso para estimar la cantidad de aromaticidad en los anillos sin benceno, como los anillos heterocíclicos, que es famoso por los compuestos químicos orgánicos como la enfermedad anticancerígena. Teórico de un método estadístico de desplazamiento químico independiente del núcleo NICS a pequeña distancia y se alternan a gran distancia en el centro de los anillos heterocíclicos. En esta investigación, hemos explorado los enfoques estadísticos a través de cálculos de SNICS-cambios químicos independientes del núcleo en el punto de vista de los movimientos Bq en el centro de los espacios de esfera de los anillos heterocíclicos de algunos medicamentos contra el cáncer. El método S-NICS es un método computacional preciso para estimar la aromaticidad en los anillos que no son de benceno, como los anillos heterocíclicos, que son moléculas estándar en los compuestos orgánicos contra el cáncer. Aunque los valores de NICS para benceno y naftaleno, etc., pueden indicarse como criterio de aromaticidad, para otras moléculas como los anillos heterocíclicos y sus derivados, los valores de S-NICS son mucho más precisos en comparación con el índice de NICS. Los compuestos heterocíclicos con buenas pilas π son buenos cacdidatos para medicamentos contra el cáncer. La precedencia de nitrógeno, oxígeno y azufre en estos compuestos los convierte en partes bioquímicas similares, como los ácidos nucleicos y. Aromaticidad del anillo heterocíclico. Esta similitud, especialmente las pilas π, dan la capacidad de interacción con ADN y ARN y los compuestos heterocíclicos

The future of document indexing: GPT and Donut revolutionize table of content processing

Industrial projects rely heavily on lengthy, complex specification documents, making tedious manual extraction of structured information a major bottleneck. This paper introduces an innovative approach to automate this process, leveraging the capabilities of two cutting-edge AI models: Donut, a model that extracts information directly from scanned documents without OCR, and OpenAI GPT-3.5 Turbo, a robust large language model. The proposed methodology is initiated by acquiring the table of contents (ToCs) from construction specification documents and subsequently structuring the ToCs text into JSON data. Remarkable accuracy is achieved, with Donut reaching 85% and GPT-3.5 Turbo reaching 89% in effectively organizing the ToCs. This landmark achievement represents a significant leap forward in document indexing, demonstrating the immense potential of AI to automate information extraction tasks across diverse document types, boosting efficiency and liberating critical resources in various industries.Comment: Document AI, Document Classification, Information extraction, Large Language Models, OCR Models, Visual Document Understandin

نقش حرارت در سلامت از دیدگاه طب سنتی و پزشکی نوین

In modern science, heat is a quality that enhances the movement of molecules. Maintenance of instinctive temperature in a normal range is vital for healthy organs' function and survival. In the Traditional Persian Medicine, the heat comprised to instinctive that is related to animal spirit and hands the animal life; and stout heat that is related to natural spirit. Instinctive which derived from main spiritual heat has no burning, decay and infection. In traditional medicine, the physician determines the body hotness and coldness of the patient with palpation. However further than palpation, the physician should evaluate the function of main body organs (heart, brain and liver) to estimate instinctive heat. The physician should be moderate in mezaj (temperament) or knows the normal moderate human's mezaj. The maintenance of instinctive heat and humidity plays vital role in healthy life style and longevity. The weather, food and drink, sleep and wake, motion and stillness, retention and evacuation and at last mood are the six main basics for maintaining instinctive temperature. Despite the differences between the definitions and terminology of both traditional and modern perspectives on the heat, the importance of body temperature in metabolism and health is mentioned in both schools. This study is about to provide a context for further attention of the researchers to basic concepts of traditional medicine.حرارت در علم نوین کیفیتی است که باعث افزایش حرکت مولکول‌ها می‏شود. بقای انسان وابسته به نگهداری حرارت درونی تا حدی است که افعال بدنی در آن به‌درستی انجام گیرد. از دیدگاه طب سنتی، حرارت دو نوع است: غریزی و اُسطُقُسی. حرارت غریزی، حرارت ذاتی است که گرمی آن سوزندگی، تعفین و فساد ندارد. در طب سنتی، طبیب برای تعیین گرمی و سردی مَلمَس بیمار از دست خود استفاده می‌کند، اما ملمس بیمار برای تعیین حرارت غریزی بیمار کافی نیست. علاوه بر ملمس، افعال اندام‌های رئیسه یعنی قلب، مغز و کبد نیز باید بررسی شوند. حفظ حرارت غریزی و رطوبت، نقش حیاتی در تندرستی و طول عمر دارد. هوا، غذا و نوشیدنی، خواب و بیداری، حرکت و سکون، احتباس و استفراغ و درنهایت، اعراض نفسانی یا حالات روحی شش اصل اساسی حفظ حرارت غریزی هستند. تغییر کیفیات مانند حرارت منجر به ایجاد سوء‏مزاج در اندام‌ها و بیماری می‏شود. باوجود تفاوت میان تعاریف و اصطلاحات دو دیدگاه سنتی و نوین درباره حرارت، در هر دو مکتب به اهمیت حفظ حرارت درونی بدن و نقش آن در سوخت‌وساز و سلامت اذعان شده است. این تحقیق بر آن است زمینه‌ای برای توجه بیشتر پژوهشگران به مفاهیم پایه‌ای طب سنتی فراهم آورد.   &nbsp

Neural Dynamics: Criticality, Cooperation, Avalanches and Entrainment between Complex Networks

Book chapter discussing neural dynamics and the criticality, cooperation, avalanches and entrainment between complex networks

Comparison of High-intensity Laser Therapy with Extracorporeal Shock Wave Therapy in the Treatment of Patients with Plantar Fasciitis: A Double-blind Randomized Clinical Trial

Background: The most common cause of heel pain is plantar fasciitis (PF). Although conservative treatments relieve pain in more than 90% of patients, it may remain painful in some cases. This study aimed to compare High-intensity Laser Therapy (HILT) with Extracorporeal Shock Wave Therapy (ESWT) in patients with PF.Methods: In this double-blinded randomized clinical trial (conducted in Yazd, Iran, from May 2020 to March 2021), patients were classified into two groups, including the ESWT and HILT, using online randomization. Nine sessions, three times a week for 3 weeks, were the treatment period in both groups. Visual Analogue Score (VAS), Heel Tenderness Index (HTI), and the SF36 questionnaire were compared and analyzed statistically at the beginning and 9 months after treatment. Results: 38 patients (19 in each group) completed the study. Results showed that pain and patient satisfaction improved significantly 3 months after treatment. The VAS and HTI decreased 3 months after treatment in both groups, which was statistically significant (P<0.001). The SF36 score in both groups increased 3 months after treatment, and this increase was statistically significant (P<0.001). Although the two modalities were effective based on VAS, HTI, and SF36, a significant statistical difference was observed between them (P=0.03, P=0.006, P=0.002, respectively), and the HILT was more effective.Conclusion: ESWT and HILT decrease pain and increase patient satisfaction in PF. Besides, both methods are non-invasive and safe. However, there is a significant difference between them, and HILT is more effective.Trial registration number: IRCT20210913052465N1

Protocol Adherence in Prehospital Medical Care Provided for Patients with Chest Pain and Loss of Consciousness; a Brief Report

Introduction: Although many protocols are available in the field of the prehospital medical care (PMC), there is still a notable gap between protocol based directions and applied clinical practice. This study measures the rate of protocol adherence in PMC provided for patients with chest pain and loss of consciousness (LOC).Method: In this cross-sectional study, 10 educated research assistants audited the situation of provided PMC for non-traumatic chest pain and LOC patients, presenting to the emergency department of a tertiary level teaching hospital, compare to national recommendations in these regards.Results: 101 cases with the mean age of 56.7 ± 12.3 years (30-78) were audited (55.4% male). 61 (60.3%) patients had chest pain and 40 (39.7%) cases had LOC. Protocol adherence rates for cardiac monitoring (62.3%), O2 therapy (32.8%), nitroglycerin administration (60.7%), and aspirin administration (52.5%) in prehospital care of patients with chest pain were fair to poor. Protocol adherence rates for correct patient positioning (25%), O2 therapy (75%), cardiac monitoring (25%), pupils examination (25%), bedside glucometery (50%), and assessing for naloxone administration (55%) in prehospital care of patients with LOC were fair to poor.Conclusion: There were more than 20% protocol violation regarding prehospital care of chest pain patients regarding cardiac monitoring, O2 therapy, and nitroglycerin and aspirin administration. There were same situation regarding O2 therapy, positioning, cardiac monitoring, pupils examination, bedside glucometery, and assessing for naloxone administration of LOC patients in prehospital setting