Situational-Context for Virtually Modeling the Elderly

The generalized aging of the population is incrementing the pressure over, frequently overextended, healthcare systems. This situations is even worse in underdeveloped, sparsely populated regions like Extremadura in Spain or Alentejo in Portugal. In this paper we propose an initial approach to use the Situational-Context, a technique to seamlessly adapt Internet of Things systems to the needs and preferences of their users, for virtually modeling the elderly. These models could be used to enhance the elderly experience when using those kind of systems without raising the need for technical skills. The proposed virtual models will also be the basis for further eldercare innovations in sparsely populated regions

Decay Constants of Heavy-Light Mesons

The decay constants of the heavy-light pseudoscalar mesons are studied in a high statistics run using the Wilson action at $\beta=6.0$ and $\beta=6.2$, and the clover action at $\beta=6.0$. The systematics of $O(a)$ discretisation errors are discussed. Our best estimates of the decay constants are: $f_D$ = 218(9) MeV, $f_D/f_{Ds}$ = 1.11(1) and we obtain preliminary values for $f_B$.Comment: at the Dallas Lattice Conference, October 1993. 3 pages in a single postscript file, uuencoded form. Rome Preprint 93/98

Psychosocial characteristics and social networks of suicidal prisoners: towards a model of suicidal behaviour in detention

Prisoners are at increased risk of suicide. Investigation of both individual and environmental risk factors may assist in developing suicide prevention policies for prisoners and other high-risk populations. We conducted a matched case-control interview study with 60 male prisoners who had made near-lethal suicide attempts in prison (cases) and 60 male prisoners who had not (controls). We compared levels of depression, hopelessness, self-esteem, impulsivity, aggression, hostility, childhood abuse, life events (including events occurring in prison), social support, and social networks in univariate and multivariate models. A range of psychosocial factors was associated with near-lethal self-harm in prisoners. Compared with controls, cases reported higher levels of depression, hopelessness, impulsivity, and aggression, and lower levels of self-esteem and social support (all p values <0.001). Adverse life events and criminal history factors were also associated with near-lethal self-harm, especially having a prior prison spell and having been bullied in prison, both of which remained significant in multivariate analyses. The findings support a model of suicidal behaviour in prisoners that incorporates imported vulnerability factors, clinical factors, and prison experiences, and underscores their interaction. Strategies to reduce self-harm and suicide in prisoners should include attention to such factors

Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells

G-quadruplex (G4) ligands are investigated to discover new anticancer drugs with increased cell-killing potency. These ligands can induce genome instability and activate innate immune genes at non-cytotoxic doses, opening the discovery of cytostatic immune-stimulating ligands. However, the interplay of G4 affinity/selectivity with cytotoxicity and immune gene activation is not well-understood. We investigated a series of closely related hydrazone derivatives to define the molecular bases of immune-stimulation activity. Although they are closely related to each other, such derivatives differ in G4 affinity, cytotoxicity, genome instability, and immune gene activation. Our findings show that G4 affinity of ligands is a critical feature for immune gene activation, whereas a high cytotoxic potency interferes with it. The balance of G4 stabilization versus cytotoxicity can determine the level of immune gene activation in cancer cells. Thus, we propose a new rationale based on low cell-killing potency and high immune stimulation to discover effective anticancer G4 ligands

To what extent is behaviour a problem in English schools?:Exploring the scale and prevalence of deficits in classroom climate

The working atmosphere in the classroom is an important variable in the process of education in schools, with several studies suggesting that classroom climate is an important influence on pupil attainment. There are wide differences in the extent to which classroom climate is considered to be a problem in English schools. Some ‘official’ reports suggest that behaviour in schools is ‘satisfactory or better’ in the vast majority of schools; other sources have pointed to behaviour being a serious and widespread problem. The paper details four studies conducted over the past decade which aimed to explore these disparities. The aim of the research was to gain a more accurate insight into the extent to which deficits in classroom climate limit educational attainment and equality of educational opportunity in English schools. The findings question the suggestion that behaviour is satisfactory or better in 99.7% of English schools and the concluding section suggests ways in which deficits in classroom climate might be addressed. Although the study is limited to classrooms in England, OECD studies suggest that deficits in the working atmosphere in classrooms occur in many countries. The study therefore has potential relevance for education systems in other countries

What's in a grade? The multidimensional nature of what teacher-assigned grades assess in high school

Historically, teacher-assigned grades have been seen as unreliable subjective measures of academic knowledge, since grades and standardized tests have traditionally correlated at about the 0.5 to 0.6 level, and thus explain about 25–35% of each other. However, emerging literature indicates that grades may be a multidimensional assessment of both student academic knowledge and a student's ability to negotiate the social processes of schooling, such as behavior, participation, and effort. This study analyzed the high school transcript component of the Education Longitudinal Study of 2002 (ELS:2002) using multidimensional scaling (MDS) to describe the relationships between core subject grades, non-core subject grades, and standardized test scores in mathematics and reading. The results indicate that when accounting for the academic knowledge component assessed through standardized tests, teacher-assigned grades may be a useful assessment of a student's ability at the non-cognitive aspects of school. Implications for practice, research, and policy are discussed

Responsabilidad social. Una propuesta desde la contabilidad social y ambiental para empresas clave de la región

En el Partido de General Pueyrredon existen empresas que se destacan por sus acciones de responsabilidad social, conformando un objeto de análisis relevante desde el punto de vista de la contabilidad social y ambiental debido a su impacto positivo en la comunidad. Por ello, mediante este proyecto se propuso relevar las políticas de responsabilidad social asumidas por dichas empresas, analizar el impacto en sus destinatarios y proponer sistemas de información contable que reflejen estas políticas y satisfagan las necesidades de los usuarios interesados. Se parte del hecho de que los usuarios del sistema contable asignan cada vez mayor relevancia a la información referida al desempeño social, ético y medioambiental de las empresas. En este sentido, las investigaciones que desde la disciplina contable y afines abordan esta temática, realizan aportes valiosos para el ejercicio de la profesión, y adicionalmente, permiten que las empresas que asumen una actitud responsable frente a diferentes problemáticas sociales puedan adecuar los informes de sus sistemas contables y dar cuenta de sus acciones a múltiples usuarios. Metodológicamente proponemos triangular nuestro objeto de investigación en base a un nutrido cuerpo teórico, información primaria relevada a través de entrevistas en profundidad e información secundaria proporcionada por las empresas seleccionadas para el estudio. Nos valemos de la teoría de los stakeholders para el marco analítico general de la investigación, y los desarrollos de la contabilidad social y ambiental para la propuesta de mejora de los informes empresariales.Fil: D'Onofrio, Paula. Universidad de Buenos Aires. Facultad de Ciencias Económicas; Argentina.Fil: Rodrigues, J. A. Universidade de São Paulo; Brasil.Fil: Iacono, C. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Dominguez Marzano, Facundo. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Hernández, R. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: Gorosito, Silvina Marcela. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina.Fil: García, F. Universidad Nacional de Mar del Plata. Facultad de Ciencias Económicas y Sociales; Argentina

Atmospheric gas absorption knowledge in the submillimeter: Modeling, field measurements, and uncertainty quantification

Members of the atmospheric and astronomical science communities met to review the current state of the art of the submillimeter spectral region. Knowledge of gas spectroscopy is still questionable at these frequencies but is important to fully exploit upcoming meteorological satellite measurements

Search for Branons at LEP

We search, in the context of extra-dimension scenarios, for the possible existence of brane fluctuations, called branons. Events with a single photon or a single Z-boson and missing energy and momentum collected with the L3 detector in e^+ e^- collisions at centre-of-mass energies sqrt{s}=189-209$ GeV are analysed. No excess over the Standard Model expectations is found and a lower limit at 95% confidence level of 103 GeV is derived for the mass of branons, for a scenario with small brane tensions. Alternatively, under the assumption of a light branon, brane tensions below 180 GeV are excluded