WEIRD – Real Use Cases and Applications for the WiMAX Technology

IEEE 802.16/WiMAX is one of the most promising technologies for Broadband Wireless Access, both for fixed and mobile use. This paper presents the structure of some testbeds, set up in the framework of the European project WEIRD, about novel applications running on top of a WiMAX-based end-to-end architecture. The presented testbeds are based on real use case scenarios, including monitoring of impervious areas, tele-medicine and tele-hospitalization

Using WiMAX technology to improve volcano monitoring: the WEIRD System

IEEE 802.16 standards (IEEE, 2004; IEEE, 2005), commonly known as WiMAX (Worldwide Interoperability for Microwave Access Forum), is one of the most promising broadband wireless access technology for next generation all-IP networks. This access technology allows reaching high bit rate and covering large areas with a single Base Station (BS). Thanks to these features, IEEE 802.16 opens the way for the use and the introduction of wireless technologies in particular emergency scenarios, like volcano monitoring. Active volcano surveillance is based prevalently on the analysis of geophysical and geochemical parameters gathered by monitoring networks. Of all, seismology is one of the most useful methods for volcano monitoring. In fact, several types of seismic signals, e.g. volcano-tectonic earthquakes (VT), long-period events (LP), volcanic tremor, can occur before and during an eruption. The analysis and interpretation of these seismic signals are a very important task for the volcanic eruption forecasting (Scarpa and Tilling, 1996). WiMAX technology can be applied to provide broadband wireless access in volcano monitoring scenarios, in order to solve all the problems that today limit the possibility to realize a real-time and accurate monitoring of volcanoes activities in emergency situations. In particular, this paper focus on a novel solution, designed within the IST FP6 EU WEIRD (WiMAX Extension to Isolated Research Data networks) Integrated Project, to perform volcano monitoring using the features offered by IEEE 802.16 networks in order to improve transmission of data acquired by temporary seismic stations deployed during emergencies. Tests performed on field demonstrate the advantages offered by the use of WiMAX compared with other commonly used technologies

Using wireless point-to-point connections to improve volcano monitoring: a feasibility study of the WiMAX technology applied to the Campi Flegrei volcanic area (Southern Italy)

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Radar Evidence of Subglacial Liquid Water on Mars

Strong radar echoes from the bottom of the martian southern polar deposits are interpreted as being due to the presence of liquid water under 1.5 km of ice

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation

Posttranslational modifications can have profound effects on the biological and biophysical properties of proteins associated with misfolding and aggregation. However, their detection and quantification in clinical samples and an understanding of the mechanisms underlying the pathological properties of misfolding- and aggregation-prone proteins remain a challenge for diagnostics and therapeutics development. We have applied an ultrasensitive immunoassay platform to develop and validate a quantitative assay for detecting a posttranslational modification (phosphorylation at residue T3) of a protein associated with polyglutamine repeat expansion, namely Huntingtin, and characterized its presence in a variety of preclinical and clinical samples. We find that T3 phosphorylation is greatly reduced in samples from Huntington\u2019s disease models and in Huntington\u2019s disease patients, and we provide evidence that bona-fide T3 phosphorylation alters Huntingtin exon 1 protein conformation and aggregation properties. These findings have significant implications for both mechanisms of disease pathogenesis and the development of therapeutics and diagnostics for Huntington\u2019s disease

EVOLUÇÃO DAS POLÍTICAS RELACIONADAS À SAÚDE DA CRIANÇA NO ÂMBITO DA ATENÇÃO PRIMÁRIA BRASILEIRA

Introdução: As políticas públicas são essenciais para reduzir a morbimortalidade infantil. Este estudo descreve a evolução das políticas relacionadas à atenção à criança no âmbito da Atenção Primária à Saúde (APS) no Brasil, implementadas desde a criação do Sistema Único de Saúde (SUS). Metodologia: Revisão narrativa da literatura com base nos principais marcos regulatórios com influência direta ou indireta na Atenção à Saúde da Criança (ACS) na APS, publicados entre 1990 e 2017. Resultados: Foram analisados ​​31 documentos oficiais, organizados em uma linha do tempo e classificados em três categorias: I) Normas do SUS e da APS; II) diretrizes para os serviços de saúde materno-infantil no âmbito da APS; e, III) políticas intersetoriais. Conclusão:A evolução das políticas de CSC no Brasil é marcada por uma série de conquistas em prol da ampliação dos direitos sociais e da garantia do direito à saúde que ampliou o acesso aos serviços de saúde e contribuiu para a melhoria das condições de vida e de vida das crianças. No entanto, as desigualdades sociais e os desafios no acesso e qualidade da atenção na APS são persistentes, com retrocessos causados ​​pela implementação de medidas de austeridade desde 2016.Introdução: Políticas públicas são fundamentais para a redução da morbimortalidade na infância. O presente estudo descreve uma evolução política relacionada à Atenção Primária à Saúde da Criança no âmbito da Atenção Primária Saúde (APS) no Brasil, desde a criação do Sistema Único de Saúde (SUS). Metodologia: Revisão narrativa da literatura com base nos principais marcos normativos com influência na Atenção à Saúde da Criança no âmbito da APS, publicados entre 1990 e 2017. Resultados: Foram analisados 31 documentos oficiais, distribuídos numa linha do tempo, classificados em: I) normatização do SUS e da APS; II) orientação aos serviços de saúde materno-infantil no âmbito da APS e III) políticas intersetoriais. Conclusão: A evolução das políticas pensadas no Brasil está marcada para serviços e como soluções da série de direitos sociais e como possibilidades de vistas da vida. Porém, além das desigualdades sociais, desafios no acesso e na qualidade do cuidado na APS se fazem persistentes, com retrocessos são persistentes agravados com a capacidade de trabalhar1 em medidas de austeridade curso desde 206

The effect of material model formulation in the stress analysis of abdominal aortic aneurysms

A reliable estimation of wall stress in Abdominal Aortic Aneurysms (AAAs), requires performing an accurate three-dimensional reconstruction of the medical image-based native geometry and modeling an appropriate constitutive law for the aneurysmal tissue material characterization. A recent study on the biaxial mechanical behavior of human AAA tissue specimens demonstrates that aneurysmal tissue behaves mechanically anisotropic. Results shown in this communication show that the peak wall stress is highly sensitive to the anisotropic model used for the stress analysis. In addition, the present investigation indicates that structural parameters (e.g., collagen fiber orientation) should be determined independently and not by means of non-linear fitting to stress-strain test data. Fiber orientation identified in this manner could lead to overestimated peak wall stresses