2,088 research outputs found
Profiles of Chicano educational opportunity 1950-1980 the significance of teacher expectations
A classified ad was printed in a Southern California newspaper requesting Chicanos who attended high school between 1950 and 1980 to discuss their school experiences. Eight interviews were conducted; one participant was a college graduate, two others were high school graduates, and the others dropped out of high school to work or start a family. The interviews illuminated how the educational system, namely teachers’ expectations, affected the academic aspirations and achievements of the participants. Interview results showed that the lack of culturally affirming relationships with teachers hindered most interviewees’ ability to make connections between hard work in school and future social and economic benefits
Linking data and disciplines: Exploring narratives through computational tools and interdisciplinary collaboration
Mesophotic coral ecosystems research strategy: international workshop to prioritize research and management needs for mesophotic coral ecosystems, Jupiter, Florida, 12-15 July 2008
On July 12-15, 2008, researchers and resource managers met in Jupiter, Florida to discuss and review the state of knowledge regarding mesophotic coral ecosystems, develop a working definition for these ecosystems, identify critical resource management information needs, and develop a Mesophotic Coral Ecosystems Research Strategy to assist the U.S. National Oceanic and Atmospheric Administration (NOAA) and other agencies and institutions in their research prioritization and strategic planning for mesophotic coral ecosystems. Workshop participants included representatives from international, Federal, and state governments; academia; and nongovernmental organizations.
The Mesophotic Coral Ecosystems Workshop was hosted by the Perry Institute for Marine Science (PIMS) and organized by NOAA and the U.S. Geological Survey (USGS). The workshop goals, objectives, schedule, and products were governed by a Steering Committee consisting of members from NOAA (National Centers for Coastal Ocean Science’s Center for Sponsored Coastal Ocean Research, the Office of Ocean Exploration and Research’s NOAA Undersea Research Program, and the National Marine Fisheries Service), USGS, PIMS, the Caribbean Coral Reef Institute, and the Bishop Museum
An Integrated Power Flow Solution of Flexible AC Transmission Systems Containing Wind Energy Conversion Systems
A Cloud Based Data Integration Framework
Virtual enterprise (VE) relies on resource sharing and collaboration across geographically dispersed and dynamically allied businesses in order to better respond to market opportunities. It is generally considered that effective data integration and management is crucial to realise the value of VE. This paper describes a cloud-based data integration framework that can be used for supporting VE to discover, explore and respond more emerging business opportunities that require instant and easy resource access and flexible on-demand development in a customer-centric approach. Motivated by a case study discussing power incident management in the Spanish Electricity System, an effective on-demand application is also implemented to demonstrate how to use this framework to solve real world problems
History-dependent relaxation and the energy scale of correlation in the Electron-Glass
We present an experimental study of the energy-relaxation in
Anderson-insulating indium-oxide films excited far from equilibrium. In
particular, we focus on the effects of history on the relaxation of the excess
conductance dG. The natural relaxation law of dG is logarithmic, namely
dG=-log(t). This may be observed over more than five decades following, for
example, cool-quenching the sample from high temperatures. On the other hand,
when the system is excited from a state S_{o} in which it has not fully reached
equilibrium to a state S_{n}, the ensuing relaxation law is logarithmic only
over time t shorter than the time t_{w} it spent in S_{o}. For times t>t_{w}
dG(t) show systematic deviation from the logarithmic dependence. It was
previously shown that when the energy imparted to the system in the excitation
process is small, this leads to dG=P(t/t_{w}) (simple-aging). Here we test the
conjecture that `simple-aging' is related to a symmetry in the relaxation
dynamics in S_{o} and S_{n}. This is done by using a new experimental procedure
that is more sensitive to deviations in the relaxation dynamics. It is shown
that simple-aging may still be obeyed (albeit with a modified P(t/t_{w})) even
when the symmetry of relaxation in S_{o} and S_{n} is perturbed by a certain
degree. The implications of these findings to the question of aging, and the
energy scale associated with correlations are discussed
CaracterizaciĂłn de ectomicorrizas en encinares productores de trufa negra del noreste de Soria
Black truffle sporocarp production is determined, amongst many other factors, by an optimum mycorrhization degree in the roots of the host-tree. This process is triggered in balance with other fungal species that does not inhibit its sporocarp production. So, there is an ectomycorrhizal
fungal community associated with the black truffle sporocarp productive host-trees that runs as any other living beings community, producing a certain fungal biodiversity and establishing connections in dynamic balance that will evolve. The absence of black truffle sporocarps production in some host-trees will be determined by its ectomycorrhiza absence, or because
between the fungal community there are one or more species that inhibit this process or displace it. With the aim of study those topics, the ectomycorrhizae present in 23 adult holmoak trees (Quercus ilex subsp. ballota (Desf.) Samp.) of seven Tuber melanosporum Vittad. productive areas in the North-West of Soria (inner Spain) are characterized and quantified. During the
spring and the autumn of 1999 and 2000, black truffle productive and non-productive holmoaks were studied following the global method (Verlhac et al., 1990, La truffe guide pratique). Ectomycorrhizal types were characterized following the guidelines of Agerer (1999). Tuber melanosporum, T. aestivum Vittad., T. brumale Vittad., Cenococcum geophylum Fr., Pisolithus
arrhizus (Scop.) Rauscher, Cantharellus tubaeformis (Bull.) Fr., Hebeloma cf. sinapizans (Fr.) Sacc., Tomentella galzinii Bourdot, AD type, Cortinarius sp., Hebeloma sp. and Scleroderma sp. and many others Telephorales, Tuberales and Boletales ectomycorrhizal types were found.
Tuber melanosporum mycorrhizae are present both in productive and non-productive hosttrees, as it happens for T. aestivum, while T. brumale ectomycorrhizae are only present in nonproductive holmoaks. The rest of identified ectomycorrhizal types are present in productive and non-productive host-trees
Ectomycorrhizal status of a mature productive black truffle plantation
The truffle-plantation «Los Quejigares» was planted in 1971 by AROTZ-CATESA company. It is a 600 ha plot of Quercus
ilexmycorrhizated with Tuber melanosporum at 1,250 m a.s.l. on calcareous soil. This plantation is the largest of the world
and one of the eldest truffle-plantations of Spain and it is in full production. Knowledge of the mycorrhizal status of a
mature black truffle plantation is significant for the improvement of truffle cultivation. Ectomycorrhizae were studied for
knowing T. melanosporum persistence and diversity and abundance of other ectomycorrhizal types. Roots of 16 holmoaks
were sampled, 12 trees produce truffle sporocarps and four did not. It was found a mean of about 35% of T. melanosporum
ectomycorrhizae in the studied trees, being this significantly higher in the productive trees. Also, 105 more different
ectomycorrhizal types were found. In spite of the high number of morphotypes found, it seems that they do not replace
T. melanosporum, showing that there is a coexistence between species in the fungal community associated to the roots
SRSF1-dependent nuclear export of C9ORF72 repeat-transcripts: targeting toxic gain-of-functions induced by protein sequestration as a selective therapeutic strategy for neuroprotection
Microsatellite repeat expansions cause several incurable and lethal neurodegenerative disorders including
ataxias, myotonic dystrophy, Huntington's disease and C9ORF72-linked amyotrophic lateral sclerosis (ALS) and
frontotemporal dementia (FTD). Abnormal repeat transcripts generated from the expanded loci are substrates
of repeat-associated non-AUG (RAN) translation, an unconventional form of translation leading to the
production of polymeric repeat proteins with cytotoxic and aggregating properties. The mechanisms involved in
the pathogenesis of microsatellite repeat expansion disorders remain a hotly debated topic. They are shared
between toxic loss/gain of functions due to intranuclear RNA foci that sequesters RNA-binding proteins and
RAN translation of repeat proteins in the cytoplasm. We recently elucidated the molecular mechanism driving
the nuclear export of C9ORF72 repeat transcripts and showed for the first time that this pathway can be
manipulated to confer neuroprotection. Strikingly, we discovered that intron-retaining C9ORF72 repeat
transcripts hijack the physiological NXF1-dependent export pathway by selective RNA-repeat sequestration of
SRSF1. Antagonizing SRSF1 and the nuclear export of C9ORF72 repeat transcripts promoted in turn the
survival of patient-derived motor neurons and suppressed neurodegeneration-associated motor deficits in
Drosophila (Hautbergue et al. Nature Communications 2017; 8:16063). In this invited Research Highlight review,
we aim to place this work in the context of our previous studies on the nuclear export of mRNAs, provide a
summary of the published research and highlight the significance of these findings as a novel therapeutic
strategy for neuroprotection in C9ORF72-ALS/FTD. In addition, we emphasize that protein sequestration, often
thought as of inducing loss-of-function mechanisms, can also trigger unwanted protein interactions and toxic
gain-of-functions
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