On the relationship between pH-dependent β-lactoglobulin self assembly and gelation dynamics

There are a lot of works in literature about the size particle of β-lactoglobulin (β-lg) at different conditions and also about its rheological properties; however, there are not works which connect both results. The aim of this work was precisely to relate the state of association of β-lg in solution with the heat-induced aggregation and the dynamics of gelation upon heating in a wide range of pH. The state of association and the heat-induced aggregation of β-lg were evaluated by the determination of its size particle at room temperature and upon heating by dynamic light scattering, while the dynamics of gelation was studied by rheological measurements in a controlled stress rheometer. The state of association of β-lg was highly dependent on pH at room temperature increasing near to its isoelectric point. The rate of heat aggregation, the size of aggregates and the dynamic of gelation of β-lg were also highly dependent on pH. Finally, a mechanism involved in β-lg gelation at different pH values is proposed. The dynamic light scattering technique proved to be a useful tool to characterize the state of association and the onset of β-lg aggregation upon heating for understanding the behaviour of these proteins, for example, under the effect of heating on the gelling properties.Fil: Martinez, María Julia. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Quimicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Quimicos.; ArgentinaFil: Pilosof, Ana Maria Renata. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Quimicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Quimicos.; Argentin

Water and health-related problems, local perception and quality of water sources in a Toba (qom) community in the Impenetrable (Chaco, Argentina)

Se presenta un estudio transdisciplinario que focaliza aspectos de la salud ambiental de las comunidades tobas (qom) en relación con la problemática hídrico-sanitaria de la región del Impenetrable chaqueño. Se obtuvo información mediante métodos de investigación participativa, observación en el ámbito doméstico, y documentación etnobotánica de especies relacionadas al manejo y uso del agua. Se registraron términos vernáculos referidos a la aptitud y el sabor del agua, así como las representaciones, actitudes y prácticas en relación con las prácticas de obtención y depuración. Asimismo se realizó una exploración microbiológica y físico-química, la que se cotejó con las categorías perceptuales. Se observó que los aspectos perceptuales estarían en tensión con la calidad higiénica del agua. Se documentaron plantas freatófitas, indicadoras de presencia agua, acuíferas, floculantes, refrescantes y mejoradoras del sabor. Los resultados de esta investigación se discuten en relación con el enfoque ecosistémico y la formulación de propuestas de intervención.We present a transdisciplinary study centering on aspects of environmental health of the Toba (qom) communities that relate to water and health problems of the Impenetrable Chaco region. Information was obtained through the methods and tools of participatory research, household participant observation, and ethnobotanical documentation of species related to water management and use. Vernacular terms referring to the suitability and taste of the water, as well as representations, attitudes and practices related to water collection and purification were recorded. In addition, a microbiological and physicochemical analysis of the water was performed and compared with the perceptual categories. It was observed that perceptual aspects were in tension with the hygienic quality of water. We documented phreatophyte plants, indicative of the presence of water, as well as plants that store water, act as flocculants, refresh the water or improve taste. The results of this research are discussed from an ecosystem approach and its relationship to the development of proposals for intervention.Fil: Martinez, Gustavo Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Córdoba. Instituto de Antropología de Córdoba; Argentina. Universidad Nacional de Cordoba. Facultad de Filosofia y Humanidades. Museo de Antropologia; ArgentinaFil: Beccaglia, Ana María. Universidad Nacional de Cordoba. Facultad de Cs.quimicas. Centro de Quimica Aplicada; ArgentinaFil: Llinares, Analia. Universidad Nacional de Cordoba. Facultad de Cs.quimicas. Centro de Quimica Aplicada; Argentin

Caracterización productiva de la Reserva Natural el Hatico en el municipio del Cerrito del departamento del Valle del Cauca.

Para la concepción de una ganadería sostenible, es necesaria la evaluación constante de parámetros productivos; para ello, es indispensable contar con información recolectada en campo, de las características de importancia económica, información que generalmente se registra en tarjetas, lo que conlleva a que exista el riesgo de pérdida o daño de la misma, además de las dificultades para hacer uso de ésta. Para que la información pueda ser utilizada es necesario digitalizarla en planillas, para después ser incorporada a softwares diseñados para su análisis; ésta información es muy útil para entender el sistema de producción globalmente y realizar análisis económicos comparativos por parte de productores e investigadores. De acuerdo a lo anterior, el objetivo de este trabajo fue recopilar y digitalizar la información de la Reserva Natural el Hatico, con el fin de caracterizar productivamente los componentes raciales existentes y de esa manera, dar herramientas a los ganaderos, para la toma de decisiones a nivel productivo. Se utilizaron los registros físicos de producción y pesaje de leche de los bovinos raza Lucerna y sus cruces, consignados en planillas físicas de los años 1975 a 1988. Se procedió a digitar y corregir información de los registros en una tabla diseñada en Excel; se organizaron y agruparon por categorías para realizar la descarga de los datos al software de la reserva. Posteriormente, la información fue depurada y analizada mediante estadística descriptiva usando los softwares R y SAS; determinando los cambios medios en el tiempo para las características productivas y algunas diferencias entre los animales puros y cruzados; para esto se utilizó estadística de tipo descriptivo. Con lo cual se pudo describir el desempeño medio de las razas para las características días de lactancia, intervalo entre partos, producción a los 305 días, producción total y edad de la vaca al parto en meses, teniendo en cuenta cada uno de los partos. Además, se estimó la correlación entre cada una de las variables con los días de lactancia para cada componente racial; se pudo concluir según los análisis que el CR 3 que estaba conformado por vacas entre 94 y 100% Lucerna siempre fue más constante en cada una de las variables, como los días de lactancia, intervalo entre partos y edad de la vaca al parto, siendo mejores productivamente por su estabilidad en cada una de las lactancias; además se pudo concluir que la raza Lucerna se destaca productivamente comparada con otras razas criollas en condiciones similares

Estudio de factibilidad y propuesta de PEI para la creación de un jardín infantil en Zipaquirá

200 Páginas.El Jardín Infantil Huellas busca proponer una nueva metodología de enseñanza para niños entre los 18 meses y los 6 años de edad del municipio de Zipaquirá. El modelo pedagógico que se plantea es el constructivista en donde se parte de la base de que el niño es constructor y participe de su propio conocimiento. También se tomaran elementos del aprendizaje significativo, y la pedagogía Waldorf que propicia experiencias reales y vivenciales. Con el ánimo de determinar la factibilidad del proyecto se realiza un estudio acerca de las necesidades de la población, llegando a la conclusión de que este es un proyecto que puede llegar a tener buena acogida en el municipio debido a que existen pocos jardines infantile

A geostatistical approach for dynamic life tables: The effect of mortality on remaining lifetime and annuities

Dynamic life tables arise as an alternative to the standard (static) life table, with the aim of incorporating the evolution of mortality over time. The parametric model introduced by Lee and Carter in 1992 for projected mortality rates in the US is one of the most outstanding and has been used a great deal since then. Different versions of the model have been developed but all of them, together with other parametric models, consider the observed mortality rates as independent observations. This is a difficult hypothesis to justify when looking at the graph of the residuals obtained with any of these methods. Methods of adjustment and prediction based on geostatistical techniques which exploit the dependence structure existing among the residuals are an alternative to classical methods. Dynamic life tables can be considered as two-way tables on a grid equally spaced in either the vertical (age) or horizontal (year) direction, and the data can be decomposed into a deterministic large-scale variation (trend) plus a stochastic small-scale variation (residuals). Our contribution consists of applying geostatistical techniques for estimating the dependence structure of the mortality data and for prediction purposes, also including the influence of the year of birth (cohort). We compare the performance of this new approach with different versions of the Lee–Carter model. Additionally, we obtain bootstrap confidence intervals for predicted qxt resulting from applying both methodologies, and we study their influence on the predictions of e65t and a65t . © 2010 Elsevier B.V. All rights reserved.This work was partially supported by grants from the MEyC (Ministerio de Educacin y Ciencia, Spain project MTM2007-62923 and project MTM2008-05152) The research by Ana Debon and Francisco Martinez-Ruiz has also been partially supported by a grant from the Generalitat Valenciana (grant No GVPRE/2008/103)Debón Aucejo, AM.; Martinez Ruiz, F.; Montes, F. (2010). A geostatistical approach for dynamic life tables: The effect of mortality on remaining lifetime and annuities. Insurance: Mathematics and Economics. 47(3):327-336. https://doi.org/10.1016/j.insmatheco.2010.07.007S32733647

Iron-caseinglycomacropeptide complexes: characterization and application in beverages

Complexing iron with organic compounds has been considered an alternative strategy to mitigate the problems associated with the level of bioavailable iron and the acceptability of products supplemented with this mineral. CMP contains specific amino acids associated with iron binding. The present study aims to optimize the conditions of Fe/CMP complex formation and understand the molecular basis of interactions between CMP and iron ions. Results showed that CMP can bind ferrous iron in a 1:1.5 M ratio, forming a stable peptide-iron complex, where CMP assembles in a tetrameric form. FTIR spectra indicated that iron binding altered the secondary structures of CMP. The iron-binding sites of CMP corresponded primarily to acid residues of Glu, Asp and sialic acid. Moreover, Fe/CMP complex remained stable in a wide pH range (2.0–6.5), suggesting the adequacy to be efficiently added in food or beverages and to keeping complexed in the digestion environment. Finally, Fe/CMP complex was added to a commercial beverage (2 mg of Fe per serving of beverage) and no changes were observed in their colour during storage. A model to explain the binding between CMP and iron is proposed. These results suggest a potential application of this peptide for iron fortification.Fil: Morales, Rocio. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Quimicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Quimicos.; ArgentinaFil: Martinez, María Julia. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Quimicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Quimicos.; ArgentinaFil: Pilosof, Ana Maria Renata. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Quimicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Quimicos.; Argentin

Women and the Making of the University of Alicante Campus: Critical Reappraisals of Modern Architecture (1982–1999)

A stroll around the University of Alicante campus is like a journey through the history of Spanish architecture of the last 40 years, as many of its buildings exemplify the best production of the period. This legacy also tells a story about the role played by female architects within the profession. In fact, a gender reading reveals that only two women, Pilar Vázquez Carrasco, the architect of the Faculty of Sciences (FS, 1982) and the Social Club I (1987), and Dolores Alonso Vera, responsible for the Higher Polytechnic School IV (HPS, 1999), have designed structures on the campus over almost four decades and out of a total of more than 50 buildings. The FS is an example of structural sincerity whose brick and concrete materials and externalisation of services provide Brutalist echoes. The HPS IV is a design exercise consisting of a series of elegant, inviting volumes and open spaces intertwined with the campus garden. This essay focuses on the comparative analysis of these two award-winning works to unveil those contributions that female authorship has brought to their solutions by relating them to comparable buildings in space, time and type, but designed by male architects.This research was funded by the Ministry of Science, Innovation and Universities, Spanish Government. Research Project Title: Women in Spanish (Post)Modern Architecture Culture, 1965–2000. Grant number: PGC2018-095905-A-I00

Black Mountain College: An Irresistible Agenda

A veces no es necesario saber para dónde se va; basta con saber hacia dónde no se quiere ir. Esa posibilidad de no tener un objetivo claro - más que el de resistirse a las convenciones o los caminos ya conocidos - ha sido poco explorada en la historia de la arquitectura. Este texto nos muestra uno de esos extraños casos, el Black Mountain College, una escuela de arquitectura que, de tanto resistir, terminó casi en el olvido, sin mucha descendencia.Sometimes it is not necessary to know where you are going, and just know where you don’t want to go. This possibility of not having a clear objective - more than that of resisting conventions or well-known paths - has been little explored in architecture history. This text shows us one of those strange cases, the Black Mountain College, an architecture school that, after too much resistance, ended almost in oblivion, without much descent

Queering California Modernism: Architectural Figurations and Media Exposure of Gay Domesticity in the Roosevelt Era

This paper examines three houses built for gay patrons on the California coast shortly before World War II. The first is the small structure that Harwell H. Harris designed for the future Arts & Architecture editor John Entenza in Santa Monica, completed in 1938; the second is this same architect’s masterpiece in Berkeley, of 1941, which he created for his lifelong friend, Weston Havens; the third, by William Alexander, is in Laguna Beach, built in 1937 to accommodate the love triangle involving author-adventurer Richard Halliburton, Paul Mooney and Alexander himself. Notwithstanding their different requirements and scales, these dwellings can be understood as dramatic observatories which, protected from inquisitive gazes, strove to see without being seen. Although the care that went into ensuring their inhabitants’ privacy might appear to conflict with the concern for making them objects of public seduction and media attention, both these strategies were inextricably intertwined. Yet, beyond the visual primacy in the organization of their interiors and the striking formal solutions to their exteriors, a comparative analysis of these houses and their physical and metaphorical modes of simulation, dissimulation and stimulation reveals the emergence of other spatial proposals, sensory invitations and symbolic registers which, as lines of flight of modernism, challenge normative ways of codifying identity, sexuality and queer affections.This research has been funded by the Ministry of Science and Innovation of the Government of Spain (Grant Code: PGC2018-095905-A-I00)

Inclusive Higher Education and the Built Environment. A Research and Teaching Agenda for Gender Mainstreaming in Architecture Studies

As one of the Sustainable Development Goals of the United Nations’ 2030 Agenda, gender equality is a necessary foundation for a peaceful and sustainable world. The integration of the frameworks of analysis and action provided by gender perspective into the design, development and assessment of any program related to university education, research and management is essential to the fulfillment of both quality higher education and an effective transfer of knowledge and values to society. Starting from a standpoint of commitment to this progressive outlook, this essay focuses on the specific case of the University of Alicante, Spain, and on its Architecture studies. It seeks to underline the achievements of this institution in the fostering of a critical spirit and the empathy of its students by way of the implementation of gender perspective as a tool for the conception of complex, diverse and integrating projects, aligned to the objective of mutual care between people and the environment. This is crucial for the co-education of future generations of architects, who will play a central role in the definition of new practices and policies related to space and materials, which favor a more sustainable, inclusive and caring scenario for both humans and non-humans.This research was partially funded by the Ministry of Science, Innovation and Universities, Spanish Government. Research Project Title: Women in Spanish (Post)Modern Architecture Culture, 1965–2000. Grant number: PGC2018-095905-A-I00. It has also benefited from a grant given by the “Cátedra de Arquitectura Sostenible”, University of Alicante and Conselleria d’Habitatge i Arquitectura Bioclimàtica de la Generalitat Valenciana (Valencia Regional Government, Spain)