55 research outputs found
Quantization for an elliptic equation of order 2m with critical exponential non-linearity
On a smoothly bounded domain we consider a sequence of
positive solutions in to
the equation subject to Dirichlet
boundary conditions, where . Assuming that
we
prove that is an integer multiple of
\Lambda_1:=(2m-1)!\vol(S^{2m}), the total -curvature of the standard
-dimensional sphere.Comment: 33 page
Existence of solutions to a higher dimensional mean-field equation on manifolds
For we prove an existence result for the equation on a closed Riemannian
manifold of dimension for certain values of .Comment: 15 Page
The role of clinically significant antiphospholipid antibodies in systemic lupus erythematosus
The objective is to investigate the role of clinically significant antiphospholipid antibodies (aPL) in a cohort of systemic lupus erythematosus (SLE) patients. All SLE patients followed for at least 5 years and with available aPL profile at the beginning of the follow-up in our center were studied. Clinically significant aPL were defined as: positive lupus anticoagulant test, anti-cardiolipin and/or anti- ÎČ2Glycoprotein I IgG/IgM >99th percentile on two or more occasions at least 12 weeks apart. Patients with and without clinically significant aPL were compared by univariate (Chi square or Fisher's exact test for categorical variables and Student's t or Mann-Whitney test for continuous variables) and multivariate analysis (logistic regression analysis). P values <0.05 were considered significant. Among 317 SLE patients studied, 117 (37%) had a clinically significant aPL profile at baseline. Such patients showed at univariate analysis an increased prevalence of deep venous thrombosis, pulmonary embolism, cardiac valvular disease, cognitive dysfunction and antiphospholipid syndrome (APS), but a reduced prevalence of acute cutaneous lupus and anti-extractable nuclear antigens (ENA) when compared with patients without clinically significant aPL. Multivariate analysis confirmed the association between clinically significant aPL and reduced risk of acute cutaneous lupus [p=0.003, odds ratio (OR) 0.43] and ENA positivity (p<0.001, OR 0.37), with increased risk of cardiac valvular disease (p=0.024, OR 3.1) and APS (p<0.0001, OR 51.12). Triple positivity was the most frequent profile and was significantly associated to APS (p<0.0001, OR 28.43). Our study showed that one third of SLE patients had clinically significant aPL, and that this is associated with an increased risk, especially for triple positive, of APS, and to a different clinical and serological pattern of disease even in the absence of APS
Asymptotics and quantization for a mean-field equation of higher order
Given a regular bounded domain , we describe the
limiting behavior of sequences of solutions to the mean field equation of order
, , under the Dirichlet boundary condition and
the bound . We emphasize the connection with the problem of
prescribing the -curvature.Comment: 21 page
A threshold phenomenon for embeddings of into Orlicz spaces
We consider a sequence of positive smooth critical points of the
Adams-Moser-Trudinger embedding of into Orlicz spaces. We study its
concentration-compactness behavior and show that if the sequence is not
precompact, then the liminf of the -norms of the functions is greater
than or equal to a positive geometric constant.Comment: 14 Page
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