W, Z and photon production in CMS

The production of electroweak bosons (photons, W and Z particles) in PbPb and pp collisions at sqrt(s) = 2.76 TeV per interacting nucleon pair has been measured with the CMS detector at the LHC. Direct photon production is studied using samples of isolated photons. W and Z bosons are reconstructed through their leptonic decay into muons. Their production rate in PbPb data is studied as a function of the centrality of the collision and compared to that in pp interactions, once normalized by the number of binary nucleon-nucleon interactions. The results are also compared to next-to-leading-order perturbative QCD calculations.Comment: Proceedings from Plenary Talk at 5th International Conference on Hard and Electromagnetic Probes of High-Energy Nuclear Collisions (Hard Probes 2012) at Cagliari (Italia

Automedicacion con antibioticos en estudiantes universitarios de Trujillo - Peru

La resistencia bacteriana es un problema mundial que está en aumento y ha sido considerada como un problema de salud pública global del siglo XXI. La automedicación es una de las formas de uso indiscriminado de antibióticos. El presente estudio busca determinar los factores asociados a la automedicación con antibióticos. OBJETIVO: Establecer qué factores se relacionan con la automedicación con antibióticos en los estudiantes universitarios de Trujillo – Perú. MATERIAL Y MÉTODOS: Se realizó un estudio observacional, retrospectivo, analítico, empleando instrumento de recolección de datos basado en un cuestionario que se llevó a cabo en la Universidad Privada Antenor Orrego, Universidad Nacional de Trujillo y Universidad Privada del Norte de Trujillo a 1000 estudiantes universitarios. RESULTADOS: Un total de 1000 personas que estudian en las Universidades de Trujillo fueron incluidas en el estudio. 70% de estudiantes universitarios se automedicaron dos o más veces durante el último año. El antibiótico más común usado para automedicación fue la amoxicilina 133 estudiantes (20,33% . No se encontró significancia estadística entre la edad (p= 0,4695); ingresos económicos mensuales (p = 0,83) ; nivel de conocimiento (p =0,2328); carreras relacionadas a ciencias de la salud (p = 0,1471) , año de estudios (p=0,1571) y automedicación con antibióticos CONCLUSIONES: Se registró una tasa de automedicación con antibióticos del 65,4%, pero no se encontró diferencia estadísticamente significativa en la asociación de edad, ingresos económicos, conocimientos previos acerca de antibióticos, carrera de estudio, año de carrera y la automedicación con antibióticos.Bacterial resistance is a global problem that is increasing. and it has been considered as a global public health problem in the XXI century. Self-medication is one of the forms of indiscriminate use of antibiotics. This study seeks to determine the factors associated with self-medication with antibiotics. OBJECTIVE: To establish what factors relate to self-medication with antibiotics in college students of Trujillo - Peru. MATERIALS AND METHODS: an observational, retrospective, analytical study was conducted using instrument data collection based on a questionnaire that was held at the Antenor Orrego Private University, National University of Trujillo and North Private University. RESULTS: One thousand students were included in this investigation. 70% of college students are self-medicating two or more times during the past year. The most common antibiotic used for self-medication was amoxicillin 133 students (20.33%) . No statistical significance was found between age (p= 0,4695); monthly income(p = 0,83) level ofknowledge (p = 0,2328); careers related to health sciences (p = 0,1471), year of study (p=0,1571)and self-medication with antibiotics. CONCLUSIONS: A rate of self-medication with antibiotics was recorded 65.4%, but no statistically significant difference was found in the association of age, income, prior knowledge about antibiotics, career , year of study and self-medication with antibiotics

Ciclofosfamida en comparación con Micofenolato como tratamientos predisponentes a contraer infecciones en pacientes con Lupus Eritematoso Sistémico

Establecer que ciclofosfamida predispone a contraer más infecciones en comparación con micofenolato en el tratamiento de pacientes con Lupus Eritematoso Sistémico del Hospital Docente Regional de Trujillo en el período comprendido entre 2013-2017. Materiales y Métodos: Es un estudio analítico, observacional, longitudinal, de cohorte retrospectiva. Se realizó la revisión de historias clínicas de pacientes con diagnóstico de Lupus Eritematoso Sistémico atendidos entre los años 2013-2017 en el Hospital Regional Docente de Trujillo. La muestra estuvo constituida por 82 pacientes con Lupus Eritematoso Sistémico, de los cuales 41 recibieron tratamiento con ciclofosfamida; y 41, con micofenolato. Para el análisis estadístico; se utilizó la prueba Chi Cuadrado de Pearson, para las variables cualitativas; y la prueba T-Student, para las variables cuantitativas; el estadígrafo utilizado fue el Riesgo Relativo (RR), con su respectivo intervalo de confianza del 95%. Resultados: Se confirmó que de los 41 pacientes tratados con ciclofosfamida, el 58.5 % presentó infecciones y el 41.5% no presentó infecciones; mientras que de los 41 pacientes tratados con micofenolato, presentaron infecciones el 31.7% y 68.3% no presentó infecciones, esta diferencia fue estadísticamente significativa (p<0.05) con RR: 1.85; IC del 95%: 1.07-3.18 Conclusiones: Los pacientes en tratamiento con Ciclofosfamida tienen mayor predisposición a infecciones que los pacientes en tratamiento con micofenolatoTo establish that cyclophosphamide predisposes to contracting more infections compared to mycophenolate in the treatment of patients with Systemic Lupus Erythematosus at the Trujillo Regional Teaching Hospital in the period between 2013-2017. Materials and Methods: It is an analytical, observational, longitudinal, retrospective cohort study. The clinical records of patients with a diagnosis of Systemic Lupus Erythematosus treated between 2013-2017 at the Trujillo Regional Teaching Hospital were reviewed. The sample consisted of 82 patients with Systemic Lupus Erythematosus, of whom 41 received treatment with cyclophosphamide; and 41, with mycophenolate. For the statistical analysis; the Pearson Chi Square test was used, for the qualitative variables; and the Student's T test, for the qualitative variables; the statistic used was the Relative Risk (RR), with its respective 95% confidence interval. Results: It was confirmed that of the 41 patients treated with cyclophosphamide, 58.5% presented infections and 41.5% did not present infections; While of the 41 patients treated with mycophenolate, 31.7% presented infections and 68.3% did not present infections, this difference was statistically significant (p <0.05) with RR: 1.85; 95% CI: 1.07-3.18 Conclusions: Patients treated with cyclophosphamide have a greater predisposition to infections than patients treated with mycophenolate.Tesi

Transfer of the central database and coordinating activities of EUROCAT to the JRC

In the framework of implementing European Commission's strategy in the field of rare diseases, the Directorate-General Joint Research Centre (DG JRC) and the Directorate-General for Health and Food Safety (DG SANTE) signed in December 2013 the Administrative Arrangement (AA) on the "Development and Maintenance of the European Platform on Rare Diseases Registration". One objective of the AA is the transfer of the European-level coordination activities of EUROCAT to the JRC. EUROCAT is a network of 55 population-based registries in 33 countries acting in the epidemiological surveillance of congenital anomalies. It covers 1/3 of the European birth population which corresponds to more than 1.7 million births/year. The EUROCAT central database contains half a million cases of children with congenital anomalies. This data enables provision of prevalence, prenatal diagnosis and perinatal mortality data, detection of teratogenic exposures among others. It develops recommendations considered for primary prevention in the Rare Diseases National Plans for medicinal drugs, food/nutrition, lifestyle, health services, environmental pollution. These results are highly relevant for European public health and may require public health action. In order to offer a sustainable solution for the continuation of EUROCAT activities, to secure the results of former work and to keep the system functioning, it was agreed that EUROCAT becomes part of the European Platform on Rare Diseases Registration, since the diseases/conditions the network is dealing with belong to the category 'rare'. This report presents the preparation phase, the negotiations and the procedures carried out for the effective transfer of the EUROCAT Central Registry including the central database and the coordinating activities to the JRC. The different types of activities and the involvement of different services (legal, IT, information security, procurement) in a concerted action are detailed. The establishment of the new JRC-EUROCAT Central Registry (CR) located at the JRC, Directorate F – Health, Consumers and Reference Materials, Health in Society Unit (former Institute for Health and Consumers Protection, Public Health Policy Support Unit) since 1st of January 2015 corresponds to the "data repository" function of the Rare Diseases Platform. The CR activities including collection of data from the registries, data management, communication with the registries, production of dissemination materials, management of the website are described. In addition, the role and functioning of the new joint JRC-EUROCAT Management Committee and JRC's role in supporting also other activities of the network (meetings of Registry Leaders, Coding Committee, Working Groups, etc.) are presented. The accomplishment of the transfer is a milestone in the development of the European Platform on Rare Diseases Registration.JRC.F.1-Health in Societ

Inteligencia emocional y rendimiento académico en la asignatura introducción al derecho de los estudiantes del I ciclo de la facultad de Derecho y Ciencia Política en la UNMSM, 2014

La investigación titulada Inteligencia emocional y rendimiento académico en la asignatura introducción al derecho de los estudiantes del I ciclo de la Facultad de Derecho y Ciencia Política en la UNMSM, 2014, se desarrolló a fin de alcanzar el objetivo de conocer el grado de relación que existe entre la Inteligencia emocional y rendimiento académico en la asignatura introducción al derecho de los estudiantes del I ciclo de la Facultad de Derecho y Ciencia Política en la UNMSM, 2014. Se diseñó un estudio no experimental y transversal con el objetivo de Conocer el grado de relación entre la Inteligencia Emocional y Rendimiento Académico en estudiantes de una universidad nacional en Lima la muestra está constituida por 186 estudiantes del I ciclo de la Facultad de Derecho. Se diseñó un instrumento para evaluar la variable independiente Inteligencia emocional, basado en el modelo de Inteligencia emocional de Goleman el cual mide cuatro dimensiones: Autoconocimiento, autoregulación, empatía y habilidades sociales. Los resultados del trabajo de campo analizados estadísticamente demuestran la existencia de una relación positiva y altamente significativa entre La Inteligencia Emocional y el Rendimiento Académico (r= 0,983, p=,000). Es decir, que a mayor nivel de Inteligencia Emocional habrá mayor nivel de Rendimiento académico en los estudiantes del I Ciclo de la Facultad de Derecho y Ciencia Política de la UNMSM, 2014. De esta manera la hipótesis general de la investigación es aceptada, y se rechaza la hipótesis nula

Identification Of Mitotically Competent SOX2+ Cells In White Matter Of Normal Human Adult Brain

SOX2 expression is linked to the undifferentiated state of stem cells in mammalian neurogenic niches. While its expression has been reported in the adult human subventricular zone (SVZ), to date it has not been detected in adult human white matter. Here we describe a population of SOX2+ cells from the white matter of the adult human temporal lobe, which proliferate and express glial markers in vitro

PVA/ alginate/ tannic acid crosslinked aerogels with low flammability and high mechanical resistance

Aerogels are ultra-light, highly porous materials derived from gels in which the solvent has been replaced by gas. Aerogels based on renewable and biodegradable materials are gained attention as environmentally friendly alternatives to conventional foam [1]. This study focuses on the mechanical, thermal, and combustion behavior of a polyvinyl alcohol (PVA), sodium alginate (SA) and tannic acid (TA) aerogel obtained by freeze-drying and ion crosslinking (Ca2+ and B - ). Aerogels containing 5g of PVA, 3g of TA, and 2g of SA exhibit the highest compressive resistance, which was increased by 30% after crosslinking (87.4 MPa/gcm -3 ). In comparison to pure PVA, the addition of TA and SA to the blends decreased its thermal degradation rate. The crosslinking further contributed to an 81% of reduction of the degradation rate (0.16 %/ºC) making samples high thermally stable. Regarding flammability samples burnt after being exposed to radiation due to the presence of the highly combustible PVA. However, the heat release rate (HRR) and fire growth (FIGRA) parameters decreased by 67% and 50% respectively when TA and SA was added to pure PVA aerogel. After crosslinking, an additional decrement of 35% in HRR and 54% in FIGRA respectively was obtained (76 kW/m2 and 1.96 kW/m2 s), which corresponds to a very low flame intensity. These results are down below of previous values reported by Wu et al.[2], who worked on PVA/SA crosslinking aerogels filled with inorganic montmorillonite. Hence, the cross-linked aerogels presented here can be considered a very promising sustainable alternative to conventional fossil-derived foams

Robo agravado analizado en el expediente N° 00357-2016

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Home range of the parthenogenetic lizard Aspidoscelis maslini (FRiTTS, 1969), on a beach strand

Se logró la caracterización del ámbito hogareño de una lagartija microendémica de la Península de Yucatán.he average home range size of A. maslini represents the smallest within the genus Aspidoscelis recorded to date (P ERRY & G ARlANd 2002), including both parthe - nogenetic [616 m 2 in Aspidosceli s unipa - rens (W RiGHT & l OWE , 1965), H ulSE 1981; 45.1 m 2 in A. cozumelus , H ERNáNdEZ -G Al - lEGOS et al. 2015] and gonochoristic species [400 m 2 in Aspidoscelis tigris (B AiRd & G iRARd , 1852), j ORGENSEN & T ANNER 1963; 306 m 2 in Aspidoscelis hyperythrus (C OPE , 1863), R OWlANd 1992]. This result con- trasts with theoretical predictions of broad home ranges for widely foraging species (H ulSE 1981; R OWlANd 1992; V ERWAijEN & V AN d AmmE 2008). Reduced home ranges at coastal habitats in other species of lizards including both sit and wait predators (R O - CHA 1999; k ACOliRiS et al. 2009) and wide foraging species (H iRTH 1963) have been recorded previously