Use of structural adhesive joints in construction applications

The Research Group of Materials Performance works in the development of structural adhesive joints and their performance in service in collaboration with some adhesive manufacturer companies. It is sought to increase the number of adhesive manufacturer companies to work with, as well as to find construction companies interested in the application of this technology.Contrato Programa de Comercialización e Internacionalización. Sistema Regional de Investigación Científica e Innovación Tecnológica. (Comunidad de Madrid; Universidad Carlos III de Madrid

Papular-purpuric gloves-and-socks syndrome. Presentation of a clinical case

Papular-Purpuric Glove-and-Sock Syndrome is a rare, infectious disease, of viral etiology, characterized by the presence of pruritus, edema and symmetrical erythema, very well defined at the wrists and ankles with a gloves-and-socks distribution. Other areas can be affected, with a moderate erythema appearing in cheeks, elbows, knees, armpits, abdomen, groin, external genitalia, internal face of the thighs and the buttocks. Erosions, small ulcers, enanthema and blisters can be observed in the oral cavity and lips, and less frequently in other mucous membranes. Complications are rare, although they can be severe, 50% of the published cases are related with the Parvovirus B19. Due to its oral involvement stomatologists should be aware of this syndrome in order to carry out a correct diagnosis of the disease.El Síndrome Papular Purpúrico en Guante y Calcetín es un síndrome raro, infeccioso, de etiología, viral que se caracteriza por la presencia de prurito, edema y eritema simétricos, muy bien delimitadas a nivel de las muñecas y de los tobillos con el aspecto en guante y calcetín. Pueden afectarse otras áreas apareciendo un eritema moderado en mejillas, codos, rodillas, axilas, abdomen, ingles, genitales externos, cara interna de muslos y glúteos. En la cavidad oral y labios y menos frecuentemente en otras membranas mucosas se pueden observar erosiones , pequeñas úlceras, enantema y vesículas. Las complicaciones son raras aunque pueden ser severas El 50% de los casos publicados están relacionados con el Parvovirus B19. La afectación oral en este síndrome hace que deba ser conocido por los estomatologos para realizar un correcto diagnostico de esta enfermedad

Use of paints in construction applications

The Research Group of Materials Performance works in collaboration with some paint manufacturer and paint applier companies. It is sought to open the scope of this activity through tests that include and link activities of both sectors. This improvement will widen the application areas to construction companies.Contrato Programa de Comercialización e Internacionalización. Sistema Regional de Investigación Científica e Innovación Tecnológica. (Comunidad de Madrid; Universidad Carlos III de Madrid

Information transmission around block trades on the Spanish stock market

Current fmancial research is placing increasing attention on the effects of large transactions, or Block Trades (BT), on the fmancial markets. In order to analyze whether BT transmit information, we assume that information can be better reflected by changes in asset true value, proxied by the midpoint of bid-ask best quotes, instead of transactions prices or returns. Moreover, following market microstructure literature, we also look at changes in relative spread and in their adverse selection component. The Madrid Stock Exchange offers us a particularly appropriate testing ground for examining these issues, since this topic has not been facilitated as in other markets till 1998. We analyze 195 BT, classified according with trading volume, the side of the market initiating the BT (buyer, seller or indeterminate initiated), its type (inside the spread, sweeping or not classified) and if they change or not the asset true value. The main result of the paper is that it seems that there is BT information transmission when we look at adverse selection spread component in the different subsample classification, but there is no significant permanent effect in returns. We also observe changes in liquidity around BTs but the effect is related with temporary spread component

Los Pioneros del cooperativismo agrario de crédito español (1880-1920)

En las dos últimas décadas del siglo XIX en España el cooperativismo de crédito orientado hacia los pequeños productores agrícolas estuvo bastante ligado a las corrientes del "Regeneracionismo conservador" y el catolicismo social. Hemos estudiado las aportaciones de dos autores: Joaquín Díaz de Rábago y Nicolás Fontes. Díaz de Rábago contó con una fuerte formación teórica y colaboró en la redacción de un proyecto de ley sobre cooperativas, pero a pesar de su influencia no consiguió potenciar ninguna actividad concreta. Nicolás Fontes representa al hombre "práctico". Sus circunstancias personales, era un importante terrateniente, lo animaron a poner en práctica un sistema de crédito destinado a ayudar a los pequeños arrendatarios. El modelo que puso en práctica se inspiraba en el Raiffeisen System, el mismo que defendía por Rábago. El desconocimiento mutuo de sus actuaciones invita a reflexionar sobre las limitaciones en la difusión del cooperativismo agrícola de crédito en España

The Difficult and tortuous path of agricultural cooperative networks in spain, 1890-1935

The rural associationism developed from the last decades of the XIX century could be consider as an answer of the agriculturists to the increasing integration of agriculture in the market, and to the effects of the Great Depression. In the case of Spain, the initiatives in this sense arose with certain delay in relation to the countries of Western Europe. The beginning of the Spanish cooperativism is closely bound to the Law of 1906. It granted the agrarian cooperatives with fiscal exemptions and other types of supports to the associates, although the process did not really accelerate until the promulgation of the law regulation in 1908

Investigational Drugs for the Treatment of Postherpetic Neuralgia: Systematic Review of Randomized Controlled Trials

The pharmacological treatment of postherpetic neuralgia (PHN) is unsatisfactory, and there is a clinical need for new approaches. Several drugs under advanced clinical development are addressed in this review. A systematic literature search was conducted in three electronic databases (Medline, Web of Science, Scopus) and in the ClinicalTrials.gov register from 1 January 2016 to 1 June 2023 to identify Phase II, III and IV clinical trials evaluating drugs for the treatment of PHN. A total of 18 clinical trials were selected evaluating 15 molecules with pharmacological actions on nine different molecular targets: Angiotensin Type 2 Receptor (AT2R) antagonism (olodanrigan), Voltage-Gated Calcium Channel (VGCC) 2 subunit inhibition (crisugabalin, mirogabalin and pregabalin), Voltage-Gated Sodium Channel (VGSC) blockade (funapide and lidocaine), Cyclooxygenase-1 (COX-1) inhibition (TRK-700), Adaptor-Associated Kinase 1 (AAK1) inhibition (LX9211), Lanthionine Synthetase C-Like Protein (LANCL) activation (LAT8881), N-Methyl-D-Aspartate (NMDA) receptor antagonism (esketamine), mu opioid receptor agonism (tramadol, oxycodone and hydromorphone) and Nerve Growth Factor (NGF) inhibition (fulranumab). In brief, there are several drugs in advanced clinical development for treating PHN with some of them reporting promising results. AT2R antagonism, AAK1 inhibition, LANCL activation and NGF inhibition are considered first-in-class analgesics. Hopefully, these trials will result in a better clinical management of PHNTraining University Lecturers program (FPU21/02736) of the Spanish Ministry of Economy and Competitiveness (MINECO

El nivel de la orientación al mercado en las empresas aseguradoras en España y en el resto de Europa : un estudio comparativo

Esta investigación extiende al conjunto de países de la Unión Europea, estudios previos sobre la orientación al mercado (OM) de las entidades aseguradoras. Utilizando una muestra de 112 empresas aseguradoras europeas, (a) se purifica la escala de medida del nivel de OM diseñada previamente por los autores (b) se examina la estructura factorial de la escala, y (c) se compara el nivel medio de OM entre empresas aseguradoras españolas y las del restod e Europa. La escala utilizada se reveló unidimensional y no aparecieron diferencias significativas en el nivel de OM entre las empresas españolas y las del resto de la UE.We extend to the European Union market preceding studies on market orientation (MO) in insurance firms. Usian a sample of 112 UE insurante firms, (a) we purify a MO scale previosly develope by the authors, (b) we examine its factor structure, and (c) we compare the mean level of MO among insurance firms in Spain and that of the rest of de UE. The measure used in the study was found to be unidimensional. Furthermore, there are no significant mean differences in market orientation between Spanish and rest-of-the-UE insurance firms.Publicad

Sample-Parallel Execution of EBCOT in Fast Mode

JPEG 2000’s most computationally expensive building block is the Embedded Block Coder with Optimized Truncation (EBCOT). This paper evaluates how encoders targeting a parallel architecture such as a GPU can increase their throughput in use cases where very high data rates are used. The compression efficiency in the less significant bit-planes is then often poor and it is beneficial to enable the Selective Arithmetic Coding Bypass style (fast mode) in order to trade a small loss in compression efficiency for a reduction of the computational complexity. More importantly, this style exposes a more finely grained parallelism that can be exploited to execute the raw coding passes, including bit-stuffing, in a sample-parallel fashion. For a latency- or memory critical application that encodes one frame at a time, EBCOT’s tier-1 is sped up between 1.1x and 2.4x compared to an optimized GPU-based implementation. When a low GPU occupancy has already been addressed by encoding multiple frames in parallel, the throughput can still be improved by 5% for high-entropy images and 27% for low-entropy images. Best results are obtained when enabling the fast mode after the fourth significant bit-plane. For most of the test images the compression rate is within 1% of the original