Some aspects of the ecology and reproduction of the small pelagic cyprinid, Rastrineobola argentea in Lake Victoria

This study concentrated on the reproductive biology of the small pelagic cyprinid Rastrineobola argentea. The results indicate that this fish is an inshore spawning species, which agrees with other recent studies. It was also found that in areas where fishing intensity was likely to be relatively high, the size at first maturity of R. argentea was reduced, which is likely to be an effect of the fish altering its reproductive strategy according to life history theory. The CPUE results showed a general trend of decreasing with distance from shore, however areas less than one kilometer from the shore were not sampled. Evidence was also found suggesting that the cestode parasite, Ligula intestinalis had an adverse effect on the maturation and fecundity of R. argentea. Some management options concerning the findings in this study are also briefly discussed. (PDF has 82 pages

New Trends and Future Opportunities in the Enzymatic Formation of C-C, C-N, and C-O bonds

Organic chemistry provides society with fundamental products we use daily. Concerns about the impact that the chemical industry has over the environment is propelling major changes in the way we manufacture chemicals. Biocatalysis offers an alternative to other synthetic approaches as it employs enzymes, Nature''s catalysts, to carry out chemical transformations. Enzymes are biodegradable, come from renewable sources, operate under mild reaction conditions, and display high selectivities in the processes they catalyse. As a highly multidisciplinary field, biocatalysis benefits from advances in different areas, and developments in the fields of molecular biology, bioinformatics, and chemical engineering have accelerated the extension of the range of available transformations (E. L. Bell et al., Nat. Rev. Meth. Prim. 2021, 1, 1–21). Recently, we surveyed advances in the expansion of the scope of biocatalysis via enzyme discovery and protein engineering (J. R. Marshall et al., Tetrahedron 2021, 82, 131926). Herein, we focus on novel enzymes currently available to the broad synthetic community for the construction of new C-C, C-N and C-O bonds, with the purpose of providing the non-specialist with new and alternative tools for chiral and sustainable chemical synthesis. © 2021 The Authors. ChemBioChem published by Wiley-VCH GmbH

An ultrasonic method for measuring fluid penetration rate into threaded contacts

Various methods have been employed to study the efficacy of multipurpose penetrating oils but these techniques do not investigate the rate which these oils penetrate surfaces. This paper outlines a novel, non-invasive ultrasonic method that provides a direct means of mapping fluid penetration in threaded systems. An apparatus with piezoelectric elements was developed to pulse ultrasonic waves into a nut specimen where the waves reflected from the threaded interface. The reflected signal amplitude shifted as fluid penetrated the thread, allowing the fluid to be mapped to provide a measure of ingress rate. The results for three fluid samples are presented. Measurements suggest the fluid tracks helically down the unloaded side of the thread and radially into the loaded thread surfaces

A New Method for the Detection of Galaxy Clusters in X-Ray Surveys

For many years the power of counting clusters of galaxies as a function of their mass has been recognized as a powerful cosmological probe; however, we are only now beginning to acquire data from dedicated surveys with sufcient sky coverage and sensitivity to measure the cluster population out to distances where the dark energy came to dominate the Universe’s evolution. One such survey uses the XMM X-ray telescope to scan a large area of sky, detecting the X-ray photons from the hot plasma that lies in the deep potential wells of massive clusters of galaxies. These clusters appear as extended (not point-like) objects, each providing just a few hundred photons in a typical observation. The detection of extended sources in such a low signal-to-noise situation is an important problem in astrophysics: we attempt to solve it by using as much prior information as possible, translating our experience with wellmeasured clusters to define a “template” cluster that can be varied and matched to the features seen in the XMM images. In this work we adapt an existing Monte Carlo analysis code for this problem. Two detection templates were dened and their suitability explored using simulated data; the method was then applied to a publically avalable XMM observation of a “blank” field. Presented are the encouraging results of this series of experiments, suggesting that this approach continue to be developed for future cluster-identication endeavours

Differential rotation of nonlinear r-modes

Differential rotation of r-modes is investigated within the nonlinear theory up to second order in the mode amplitude in the case of a slowly-rotating, Newtonian, barotropic, perfect-fluid star. We find a nonlinear extension of the linear r-mode, which represents differential rotation that produces large scale drifts of fluid elements along stellar latitudes. This solution includes a piece induced by first-order quantities and another one which is a pure second-order effect. Since the latter is stratified on cylinders, it cannot cancel differential rotation induced by first-order quantities, which is not stratified on cylinders. It is shown that, unlikely the situation in the linearized theory, r-modes do not preserve vorticity of fluid elements at second-order. It is also shown that the physical angular momentum and energy of the perturbation are, in general, different from the corresponding canonical quantities.Comment: 9 pages, revtex4; section III revised, comments added in Introduction and Conclusions, references updated; to appear in Phys. Rev.

Hyperbaric oxygen therapy to treat acute sport-related traumatic brain injuries: A case series

We report on hyperbaric oxygen (HBO2) therapy used to improve postinjury outcomes in eight acutely concussed high school student-athletes (5 males, 3 females, mean age = 16.0 ± 1.2 years). Patients were randomly assigned into one of three intervention groups: (a) HBO2 therapy; (b) hyperbaric therapy with compressed medical-grade air (HBA); or (c) normobaric 100% O2 therapy. All patients completed five 1-hr treatments within the first 10 days following his or her concussion. Main outcome measures included mental status examination, symptom burden, and the number of days from injury until the physician permitted the student-athlete to return to activity. Patients receiving HBO2 treatment experienced the greatest absolute symptom reduction over the five treatment sessions. No meaningful differences were found in mental status examination. All participants returned to activity in a similar timeframe. HBO2 therapy may be an effective option for the acute treatment of postconcussion symptoms, particularly in young athletes presenting with a high symptom burden

Microscopic theory of weak pseudogap behavior in the underdoped cuprate superconductors I: General theory and quasiparticle properties

We derive in detail a novel solution of the spin fermion model which is valid in the quasi-static limit pi T<<omega_sf, found in the intermediate (pseudoscaling) regime of the magnetic phase diagram of cuprate superconductors, and use it to obtain results for the temperature and doping dependence of the single particle spectral density, the electron-spin fluctuation vertex function, and the low frequency dynamical spin susceptibility. The resulting strong anisotropy of the spectral density and the vertex function lead to the qualitatively different behavior of_hot_ (around k=(pi,0)) and_cold_ (around k=(pi/2,pi/2)) quasiparticles seen in ARPES experiments. We find that the broad high energy features found in ARPES measurements of the spectral density of the underdoped cuprate superconductors are determined by strong antiferromagnetic (AF) correlations and incoherent precursor effects of an SDW state, with reduced renormalized effective coupling constant. The electron spin-fluctuation vertex function, i.e. the effective interaction of low energy quasiparticles and spin degrees of freedom, is found to be strongly anisotropic and enhanced for hot quasiparticles; the corresponding charge-fluctuation vertex is considerably diminished. We thus demonstrate that, once established, strong AF correlations act to reduce substantially the effective electron-phonon coupling constant in cuprate superconductors.Comment: REVTEX with EPS figures, uses multicol.sty, epsfig,sty, psfig.st

Trunk and lower extremity movement patterns, stress fracture risk factors, and biomarkers of bone turnover in military trainees

Context: Military service members commonly sustain lower extremity stress fractures (SFx). How SFx risk factors influence bone metabolism is unknown. Understanding how SFx risk factors influence bone metabolism may help to optimize risk-mitigation strategies. Objective: To determine how SFx risk factors influence bone metabolism. Design: Cross-sectional study. Setting: Military service academy. Patients or Other Participants: Forty-five men (agepre ¼ 18.56 6 1.39 years, heightpre ¼ 176.95 6 7.29 cm, masspre ¼ 77.20 6 9.40 kg; body mass indexpre ¼ 24.68 6 2.87) who completed Cadet Basic Training (CBT). Individuals with neurologic or metabolic disorders were excluded. Intervention(s): We assessed SFx risk factors (independent variables) with (1) the Landing Error Scoring System (LESS), (2) self-reported injury and physical activity questionnaires, and (3) physical fitness tests. We assessed bone biomarkers (dependent variables; procollagen type I amino-terminal propeptide [PINP] and cross-linked collagen telopeptide [CTx-1]) via serum. Main Outcome Measure(s): A markerless motion-capture system was used to analyze trunk and lower extremity biomechanics via the LESS. Serum samples were collected post-CBT; enzyme-linked immunosorbent assays determined PINP and CTx-1 concentrations, and PINP: CTx-1 ratios were calculated. Linear regression models demonstrated associations between SFx risk factors and PINP and CTx-1 concentrations and PINP: CTx-1 ratio. Biomarker concentration mean differences with 95% confidence intervals were calculated. Significance was set a priori using a ≤ .10 for simple and a ≤ .05 for multiple regression analyses. Results: The multiple regression models incorporating LESS and SFx risk factor data predicted the PINP concentration (R2 ¼ 0.47, P ¼ .02) and PINP: CTx-1 ratio (R2 ¼ 0.66, P ¼ .01). The PINP concentration was increased by foot internal rotation, trunk flexion, CBT injury, sit-up score, and pre- to post-CBT mass changes. The CTx-1 concentration was increased by heel-to-toe landing and post-CBT mass. The PINP: CTx-1 ratio was increased by foot internal rotation, lower extremity sagittal-plane displacement (inversely), CBT injury, sit-up score, and pre- to post-CBT mass changes. Conclusions: Stress fracture risk factors accounted for 66% of the PINP: CTx-1 ratio variability, a potential surrogate for bone health. Our findings provide insight into how SFx risk factors influence bone health. This information can help guide SFx risk-mitigation strategies

Simulation methods in the healthcare systems

International audienceHealthcare systems can be considered as large-scale complex systems. They need to be well managed in order to create the desired values for its stakeholders as the patients, the medical staff and the industrials working for healthcare. Many simulation methods coming from other sectors have already proved their added value for healthcare. However, based on our experience in the French heath sector (Jean et al. 2012), we found these methods are not widely used in comparison with other areas as manufacturing and logistic. This paper presents a literature review of the healthcare issue and major simulations methods used to address them. This work is design to suggest how more systematic creation of solutions may be performed using complementary methods to resolve a common issue. We believe that this first work can help to better understand the simulation approaches used for health workers, deciders or researchers of any responsibility level