Constraining spatial pattern of early activity of comet 67P/C-G with 3D modeling of the MIRO observations

Our aim is to investigate early activity (July 2014) of 67P/CG with 3D coma and radiative transfer modeling of MIRO measurements, accounting for nucleus shape, illumination, and orientation of the comet. We investigate MIRO line shape information for spatial distribution of water activity on the nucleus during the onset of activity. During this period we show that MIRO line shape have enough information to clearly isolate contribution from Hapi and Inhotep independently, and compare it to the nominal case of activity from the entire illuminated surface. We also demonstrate that spectral line shapes differ from the 1D model for different viewing geometries and coma conditions relevant to this study. Specifically, line shapes are somewhat sensitive to the location of the terminator in the coma. At last, fitting the MIRO observations we show that the Imhotep region (possible extended source of H$_{2}$O due to CO$_{2}$ activity) contributes only a small fraction of the total number of water molecules into MIRO beam in the early activity. On the other hand, a strong enhancement of water activity from the Hapi region seems required to fit the MIRO line shapes. This is consistent with earlier Rosetta results. Nevertheless, within the assumption of our coma and surface boundary conditions, we cannot get a reasonable fit to all MIRO mapping observations in July 2014, which may illustrate that a more sophisticated coma model or more accurate temperature/velocity distribution is needed.Comment: 22 pages, 15 figures, submitte

Volatile Content of 4-Vesta: Evidence from Unequilibrated Eucrites

Eucrites are a class of basaltic meteorites that, along with the howardites and diogenites, likely derive from the asteroid 4-Vesta. This asteroid is depleted in moderately volatile elements relative to the Earth and carbonaceous chondrites. Extrapolation of this depletion trend predicts that bulk silicate 4-Vesta (BSV) contains at most 250-1000 g/g H2O, which is approximately a factor of two lower than the H2O content of Earth. To obtain more accurate H2O and F estimates for BSV, we examined four unequilibrated antarctic meteorites, Yamato(Y)-793548, Y-82210, Y-75011, and Y-74450, by EPMA and SIMS. Pyroxenes contain MgO-rich cores and FeO-rich rims, consistent with primary magmatic zoning. Volatile concentrations generally follow patterns expected for growth zoning with lower values in the cores and higher in the rims. These features indicate that thermal metamorphism and other post-crystallization processes did not significantly perturb the volatile contents of these unequilibrated eucrite pyroxenes. We used these data to derive best estimates for the BSV H2O and F content based on experimentally determined pyroxene-melt partition coefficients and models for magma generation on Vesta. In addition, we measured D/H in the early crystallizing pyroxenes and late crystallzing apatites. We find that the D/H of pyroxene and apatite are within error of one another as well as previous measurements of apatite in equilibrated eucrites. These results imply that degassing was minimal or did not fractionate D/H. Degassing may have been limited if eucrites were shallowly emplaced sills or dykes, or the total H2O content of the magmas was too low for vapor saturation. An alternative mechanism for limited D/H fractionation is that degassing did occur, but the H2/H2O of the exsolved vapor was approximately 15:85, as predicted from experiments

Health-related quality of life in women with endometriosis:psychometric validation of the Endometriosis Health Profile 30 questionnaire using confirmatory factor analysis

STUDY QUESTION: Which of the competing models of the Endometriosis Health Profile 30 Questionnaire (EHP-30) factor structure is best supported by confirmatory factor analysis (CFA)? SUMMARY ANSWER: Findings support a five-factor first-order model of the EHP-30, thereby lending support to the model originally suggested by the questionnaire developers. WHAT IS KNOWN ALREADY: Endometriosis has a negative impact on quality of life, and measures specifically developed to address this impact, such as the EHP-30, are vital in research and disease management. Previous studies have found different models of the EHP-30 factor structure, and generated uncertainty regarding how to use the questionnaire. CFA can be applied to compare competing factor models and determine the underlying structure of a questionnaire. STUDY DESIGN, SIZE, DURATION: This cross-sectional multicenter study included 304 women with endometriosis recruited from three different public health service endometriosis clinics (referral centers for treatment of severe endometriosis) and the Danish Endometriosis Patients Association from 2014 to 2015. PARTICIPANTS/MATERIALS, SETTING, METHODS: Diagnosis of endometriosis was confirmed in medical records for 84.2% and by histology for 66.8% of participants. Questionnaires (the licensed Danish version of the EHP-30) were sent by post two times with a 6- to 12-week interval. CFA was used to examine construct validity and Bland–Altman plots to examine test–retest reliability and the convergent validity with the Short Form 36 version 2. MAIN RESULTS AND THE ROLE OF CHANCE: Response rate was high (87.6%). CFA supported the original first-order five-factor structure of the EHP-30, and thereby, the use of five separate scale-scores in clinical and research practice. Visual inspection of Bland–Altman plots suggested excellent test–retest reliability of the EHP-30 and supported the use of a disease specific quality of life instrument for women with endometriosis. LIMITATIONS, REASONS FOR CAUTION: Diagnosis could not be confirmed through histology data in 33.2% of participants. However, subgroup analyses based on women with confirmed histology only, yielded similar results. Data related to menstrual cycle stage and the use of hormonal and pain medication during questionnaire completion were not collected. A larger study, including data from different countries on different continents, would be better designed to exclude potential population bias. WIDER IMPLICATIONS OF THE FINDINGS: EHP-30, with its original five-factor structure, appears to be a valid, stable, and specific quality of life measure for women with endometriosis. It seems easy to understand, quick to administer, and importantly, scoring might be unaffected by cyclical/menstrual pain symptoms related to endometriosis. The finding of a five-factor model from different studies across several countries supports the crosscultural validity of the EHP-30. STUDY FUNDING/COMPETING INTEREST(S): This work was supported by the Danish Endometriosis Association, which is a nongovernmental organization run by women with endometriosis and by a scholarship from the Health Research Fund of Central Denmark Region. The authors have no conflicts of interest. TRIAL REGISTRATION NUMBER: The Danish Data Protection Agency (J.nr: 2013-41-2264)

Simulation of Ablating Hypersonic Vehicles with Finite-Rate Surface Chemistry

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/140434/1/6.2014-2124.pd

The stellar content of the young open cluster Trumpler 37

With an apparent cluster diameter of 1.5{\deg} and an age of ~4 Myr, Trumpler 37 is an ideal target for photometric monitoring of young stars as well as for the search of planetary transits, eclipsing binaries and other sources of variability. The YETI consortium has monitored Trumpler 37 throughout 2010 and 2011 to obtain a comprehensive view of variable phenomena in this region. In this first paper we present the cluster properties and membership determination as derived from an extensive investigation of the literature. We also compared the coordinate list to some YETI images. For 1872 stars we found literature data. Among them 774 have high probability of being member and 125 a medium probability. Based on infrared data we re-calculate a cluster extinction of 0.9-1.2 mag. We can confirm the age and distance to be 3-5 Myr and ~870 pc. Stellar masses are determined from theoretical models and the mass function is fitted with a power-law index of alpha=1.90 (0.1-0.4 M_sun) and alpha=1.12 (1-10 M_sun).Comment: 9 pages, 10 figures, 2 long tables, accepte