911 research outputs found
Evaluación de los suelos de la comarca del Aljarafe
58 páginas, 6 cuadros, 27 referencias.-- 1 mapa de suelos.-- Memoria final presentada al XXIV Curso Internacional de Edafología y Biología Vegetal, patrocinado por UNESCO-AECI y CSIC que desde 1963 hasta 2009 se ha impartido en el Centro de Edafología y Biología Aplicada del Cuarto (CEBAC), que desde 1987 pasó a denominarse Instituto de Recursos Naturales y Agrobiología de Sevilla (IRNAS-CSIC).-- Existe un ejemplar de la publicación en la Biblioteca del Instituto de Recursos Naturales y Agrobiología de Sevilla-CSIC, para su consulta.Director del trabajo: Mudarra Gómez, José LuisEste trabajo se refiere a la caracterización, cartografía y evaluación de los suelos de la comarca de El Aljarafe (Sevilla). La fase de caracterización y cartografía fue realizada en los años 1983 y 1984 por la Unidad Estructural de Investigación de Cartografía y Evaluación de Suelos del Centro de Edafología y Biología Aplicada del Cuarto, que dirige el Dr. D. José Luis Mudarra Gómez, con la colaboración del Ayudante de Investigación D. Antonio Rosales Sánchez y los alumnos del XX y XXI Curso Internacional de Edafología.El presente informe corresponde a la continuación de un trabajo que se ha venido realizando desde años anteriores y dentro del programa de investigación denominado "Estudio de las condiciones de fertilidad de los suelos españoles de mayor interés agrícola" del Consejo Superior de Investigaciones Científicas. Proyecto 2252.01.Peer reviewe
Large Area Crop Inventory Experiment (LACIE). LACIE transition year plan for the direct estimation of wheat from LANDSAT imagery
There are no author-identified significant results in this report
Integrating autonomous Problem Resolution Models with Remedy
This paper briefly defines the concept of Problem Resolution Model and shows possible approaches to the issues which may arise when integrating various PRMs to present a consistent view to the end user, despite of the peculiarities of each physical implementation. Integration refers to various autonomous PRMs having to interact as problems pass from one to another in the resolution flow. This process should be transparent to the user and internally there must be a way to track in which stage of the resolution process any problem is. This means addressing two different issues. On one side PRMs which are to be integrated need to comply with certain interface standards. These standards must ensure that problems exchanged between them can always be traced. On the other side problems owned by different PRMs should be presented to the end user under a homogeneous view. This means having an uniform criteria for automatic notification messages, a single reference point (www) where users can query the status of problems regardless who owns them , etc. Remedy is a specialized development system designed to implement PRMs and it is the current choice of IT Division for such a system. When integrating Remedy based PRMs system there are some difficulties arising which are intrinsic to Remedy's design. In this paper we describe our assessment of those difficulties and their Remedy specific implementational implications
Implementing Problem Resolution Models in Remedy
This paper defines the concept of Problem Resolution Model (PRM) and describes the current implementation made by the User Support unit at CERN. One of the main challenges of User Support services in any High Energy Physics institute/organization is to address solving of the computing-relatedproblems faced by their researchers. The User Support group at CERN is the IT unit in charge of modeling the operations of the Help Desk and acts as asecond level support to some of the support lines whose problems are receptioned at the Help Desk. The motivation behind the use of a PRM is to provide well defined procedures and methods to react in an efficient way to a request for solving a problem,providing advice, information etc. A PRM is materialized on a workflow which has a set of defined states in which a problem can be. Problems move from onestate to another according to actions as decided by the person who is handling them. A PRM can be implemented by a computer application, generallyreferred to as Problem Reporting Management System (PRMS). Through this application problems can be effectively guided through the states of theworkflow by applying actions on them. This automatic handling improves problem resolution times and provides flexible incorporation of the problems inthe workflow (either by email, the helpdesk operator etc.). It also provides registration and accounting of problems including the creation of a knowledgebase, reporting, performance measurement, etc. For such implementation we have used Remedy, which is the current choice of the IT Division at CERN fora PRMS. Remedy is an specialized development system to create PRM applications. We have developed a complete Remedy application to implement theUser Support PRM. Also, we have created complementary tools for reporting, statistics, backups, etc. The aim of this paper is to explain all these concepts and the main issues behind their implementation
Cell death induced by the application of alternating magnetic fields to nanoparticle-loaded dendritic cells
In this work, the capability of primary, monocyte-derived dendritic cells
(DCs) to uptake iron oxide magnetic nanoparticles (MNPs) is assessed and a
strategy to induce selective cell death in these MNP-loaded DCs using external
alternating magnetic fields (AMFs) is reported. No significant decrease in the
cell viability of MNP-loaded DCs, compared to the control samples, was observed
after five days of culture. The amount of MNPs incorporated into the cytoplasm
was measured by magnetometry, which confirmed that 1 to 5 pg of the particles
were uploaded per cell. The intracellular distribution of these MNPs, assessed
by transmission electron microscopy, was found to be primarily inside the
endosomic structures. These cells were then subjected to an AMF for 30 min, and
the viability of the blank DCs (i.e., without MNPs), which were used as control
samples, remained essentially unaffected. However, a remarkable decrease of
viability from approximately 90% to 2-5% of DCs previously loaded with MNPs was
observed after the same 30 min exposure to an AMF. The same results were
obtained using MNPs having either positive (NH2+) or negative (COOH-) surface
functional groups. In spite of the massive cell death induced by application of
AMF to MNP-loaded DCs, the amount of incorporated magnetic particles did not
raise the temperature of the cell culture. Clear morphological changes at the
cell structure after magnetic field application were observed using scanning
electron microscopy. Therefore, local damage produced by the MNPs could be the
main mechanism for the selective cell death of MNP-loaded DCs under an AMF.
Based on the ability of these cells to evade the reticuloendothelial system,
these complexes combined with an AMF should be considered as a potentially
powerful tool for tumour therapy.Comment: In Press. 33 pages, 11 figure
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