Effects of Branched Chain Amino Acid Supplementation on Post-Exercise Muscle Recovery and Muscle Growth

BCAA supplements are composed of three main essential amino acids, including leucine, isoleucine, and valine. The concept of BCAA supplementation comes from the fact that essential amino acids cannot be made by the body and must be derived from food and diet, as amino acids are the building blocks of proteins and muscle. Thus, by increasing intake of these essential amino acids, BCAAs are believed to reduce the effects of exercise-induced muscle damage (EIMD) by increasing availability of these important compounds. However, BCAAs are not approved by the Food & Drug Administration (FDA) as the FDA does not regulate dietary supplements (Workout supplements, 2021). Some evidence supports BCAA\u27s ability to reduce EIMD with chronic supplementation (\u3e10 days) at high intakes (\u3e200 mg/kg/day) at least twice daily, rather than showing immediate effects with short-term intake (Fouré & Bendahan, 2017). BCAAs ability to stimulate muscle growth remains unclear as there is conflicting evidence that suggests BCAA supplementation may cause some increases, yet less than that of other supplements such as whey protein (Jackman et al., 2017). Therefore, this review examines the effects of BCAAs, and whether the evidence supports these advertised benefits marketed by exercise supplement companies

Tunable BODIPY derivatives amenable to "click" and peptide chemistry

Novel azido- and amino- functionalised fluorescent probes based on the BODIPY framework have been developed. The probes can be easily and cheaply synthesised, exhibit the highly desirable BODIPY fluorescent properties, and are amenable to “click” and peptide chemistry methodologies. These probes provide a stable and readily available tool amenable for the visualisation of both solution and solid supported events

Nesting Success of Kemp’s Ridley Sea Turtles, Lepidochelys kempi, at Rancho Nuevo, Tamaulipas, Mexico, 1982–2004

The Kemp’s ridley sea turtle, Lepidochelys kempi, was on the edge of extinction owing to a combination of intense egg harvesting and incidental capture in commercial fishing trawls. Results from a cooperative conservation strategy initiated in 1978 between Mexico and the United States to protect and restore the Kemp’s ridley turtle at the main nesting beach at Rancho Nuevo, Tamaulipas, Mexico are assessed. This strategy appears to be working as there are signs that the species is starting to make a recovery. Recovery indicators include: 1) increased numbers of nesting turtles, 2) increased numbers of 100+ turtle nesting aggregations (arribadas), 3) an expanding nesting season now extending from March to August, and 4) significant nighttime nesting since 2003. The population low point at Rancho Nuevo was in 1985 (706 nests) and the population began to significantly increase in 1997 (1,514 nests), growing to over 4,000 nests in 2004. The size and numbers of arribadas have increased each year since 1983 but have yet to exceed the 1,000+ mark; most arribadas are still 200–800+ turtles

The effect of the environment on the Faber Jackson relation

We investigate the effect of the environment on the Faber Jackson (FJ) relation, using a sample of 384 nearby elliptical galaxies and estimating objectively their environment on the typical scale of galaxy clusters. We show that the intrinsic scatter of the FJ is significantly reduced when ellipticals in high density environments are compared to ellipticals in low density ones. This result, which holds on a limited range of overdensities, is likely to provide an important observational link between scaling relations and formation mechanisms in galaxies.Comment: accepted by Ap

Differentiating human versus non-human bone by exploring the nutrient foramen: implications for forensic anthropology

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/)One of the roles of a forensic anthropologist is to assist medico-legal investigations in the identification of human skeletal remains. In some instances, only small fragments of bone may be present. In this study, a non-destructive novel technique is presented to distinguish between human and non-human long bones. This technique is based on the macroscopic and computed tomography (CT) analysis of nutrient foramina. The nutrient foramen of long bone diaphyses transmits the nutrient artery which provides much of the oxygen and nutrients to the bone. The nutrient foramen and its canal were analysed in six femora and humeri of human, sheep (Ovies aries) and pig (Sus scrofa) species. The location, position and direction of the nutrient foramina were measured macroscopically. The length of the canal, angle of the canal, circumference and area of the entrance of the foramen were measured from CT images. Macroscopic analysis revealed the femora nutrient foramina are more proximal, whereas humeri foramina are more distal. The human bones and sheep humerus conform to the perceived directionality, but the pig bones and sheep femur do not. Amongst the parameters measured in the CT analysis, the angle of the canal had a discriminatory power. This study shows the potential of this technique to be used independently or complementary to other methods in distinguishing between human and non-human bone in forensic anthropology

Sharp and blunt force trauma concealment by thermal alteration in homicides: an in-vitro experiment for methodology and protocol development in forensic anthropological analysis of burnt bones

Burning of human remains is one method used by perpetrators to conceal fatal trauma and expert opinions regarding the degree of skeletal evidence concealment are often disparate. This experiment aimed to reduce this incongruence in forensic anthropological interpretation of burned human remains and implicitly contribute to the development of research methodologies sufficiently robust to withstand forensic scrutiny in the courtroom. We have tested the influence of thermal alteration on pre-existing sharp and blunt trauma on twenty juvenile sheep radii in the laboratory using an automated impact testing system and an electric furnace. The testing conditions simulated a worst-case scenario where remains with pre-existing sharp or blunt trauma were exposed to burning with an intentional vehicular fire scenario in mind. All impact parameters as well as the burning conditions were based on those most commonly encountered in forensic cases and maintained constant throughout the experiment. The results have shown that signatures associated with sharp and blunt force trauma were not masked by heat exposure and highlights the potential for future standardization of fracture analysis in burned bone. Our results further emphasize the recommendation given by other experts on handling, processing and recording burned remains at the crime scene and mortuary