46 research outputs found
High-resolution dynamic imaging and quantitative analysis of lung cancer xenografts in nude mice using clinical PET/CT
No full textMODULATION OF VASOPRESSIN-ELICITED WATER TRANSPORT BY TRAFFICKING OF AQUAPORIN2-CONTAINING VESICLES
No full textVasopressin or AVP regulates water reabsorption by the kidney inner medullary collecting duct (IMCD) through the insertion and removal of aquaporin (AQP) 2 water channels into the IMCD apical membrane. AVP-elicited trafficking of AQP2 with the apical membrane occurs via a specialized population of vesicles that resemble synaptic vesicles in neurons. AQP2 vesicles and the IMCD apical membrane contain homologs of vesicle-targeting and signal transduction proteins found in neurons. Expression studies of AQP2, including human AQP2 mutants, suggest that the carboxyl-terminal domain of AQP2 is important in AQP2 trafficking, particularly as a site for cAMP-dependent protein kinase phosphorylation. These present data reveal that IMCD cells possess a complex integrated-signaling and vesicle-trafficking machinery that provides integration of AVP-elicited water transport with many other parameters within the IMCD cell as well as kidney
Anti‐nuclear activism in the USSR and its successor states: A surrogate for nationalism?
No full textThe problem with revisionism: how new data on the origins of modern football have led to hasty conclusions
No full textThe Prevalence of Skin Disease Among School Children in Rural Ethiopia—A Preliminary Assessment of Dermatologic Needs
No full textThree men and two villages: the influence of footballers from rural South Yorkshire on the early development of the game in Sheffield
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