Pemberian Ekstrak Batang Pohon Pisang Ambon (Musa paradisiaca var. sapientum) Untuk Mempercepat Proses Hemostasis Pada Mencit(Mus muscullus)

Background: In dentistry, tooth extraction sometimes cause postoperative and perioperative comp lications especially in patients with bleeding disorder. Uncontrolled bleeding during tooth extraction may cause some effects such as hypovolemic shock, difficulty of wound healing and it become sa port de entre of pathogenic bacteria that couldlead to an infection. The using of local and systemic haemostatic may cause some side effects for the patients such as alveolar bone necrosis in the socket. Herb plants that can be used to accelerate bleedings, in the population of Trunyans, Bali, is the hump ofbanana ambon. Musa paradisiaca var. sapientumhumpcontains several active compounds such as tannin and lectin. Tanin serve s to incrase the secretion of ADP in the process of platelet agrregration whereas lectin can incrase secretion of von Wilebrand Factor (vWF) in the process of platelet adhesion on the injury vessels. Purpose: To know the influence of granting Musa paradisiaca var. sapientumhump extract in concentration of 25%, 50% and 100% againts haemostatic response on mice. Methods: A whole research sample divided into four groups. Group 1 is control, group of 2 was given 25% extract concentration, group of 3 w as given 50% extract concentration and group of 4 w as given 100% extract concentration of Musa paradisiaca var. sapientum humps. Then all the groups were examined their bleeding time and clotting time. Results: A group with 100% extract of Musa paradisiaca var. sapientum hump having the shortest bleeding time and clotting time. Conclusion: Musa paradisiaca var. sapientum hump extract with concentration of 25%, 50% and 100% could shortening bleeding and clotting time on mice

The State of Self-Organized Criticality of the Sun During the Last 3 Solar Cycles. I. Observations

We analyze the occurrence frequency distributions of peak fluxes $P$, total fluxes $E$, and durations $T$ of solar flares over the last three solar cycles (during 1980--2010) from hard X-ray data of HXRBS/SMM, BATSE/CGRO, and RHESSI. From the synthesized data we find powerlaw slopes with mean values of $\alpha_P=1.72\pm0.08$ for the peak flux, $\alpha_E=1.60\pm0.14$ for the total flux, and $\alpha_T=1.98\pm0.35$ for flare durations. We find a systematic anti-correlation of the powerlaw slope of peak fluxes as a function of the solar cycle, varying with an approximate sinusoidal variation $\alpha_P(t)=\alpha_0+\Delta \alpha \cos{[2\pi (t-t_0)/T_{cycle}]}$, with a mean of $\alpha_0=1.73$, a variation of $\Delta \alpha =0.14$, a solar cycle period $T_{cycle}=12.6$ yrs, and a cycle minimum time $t_0=1984.1$. The powerlaw slope is flattest during the maximum of a solar cycle, which indicates a higher magnetic complexity of the solar corona that leads to an overproportional rate of powerful flares.Comment: subm. to Solar Physic

Energy-Dependent Timing of Thermal Emission in Solar Flares

We report solar flare plasma to be multi-thermal in nature based on the theoretical model and study of the energy-dependent timing of thermal emission in ten M-class flares. We employ high-resolution X-ray spectra observed by the Si detector of the "Solar X-ray Spectrometer" (SOXS). The SOXS onboard the Indian GSAT-2 spacecraft was launched by the GSLV-D2 rocket on 8 May 2003. Firstly we model the spectral evolution of the X-ray line and continuum emission flux F(\epsilon) from the flare by integrating a series of isothermal plasma flux. We find that multi-temperature integrated flux F(\epsilon) is a power-law function of \epsilon with a spectral index (\gamma) \approx -4.65. Next, based on spectral-temporal evolution of the flares we find that the emission in the energy range E= 4 - 15 keV is dominated by temperatures of T= 12 - 50 MK, while the multi-thermal power-law DEM index (\gamma) varies in the range of -4.4 and -5.7. The temporal evolution of the X-ray flux F(\epsilon,t) assuming a multi-temperature plasma governed by thermal conduction cooling reveals that the temperature-dependent cooling time varies between 296 and 4640 s and the electron density (n_e) varies in the range of n_e= (1.77-29.3)*10^10 cm-3. Employing temporal evolution technique in the current study as an alternative method for separating thermal from non-thermal components in the energy spectra, we measure the break-energy point ranging between 14 and 21\pm1.0 keV.Comment: Solar Physics, in pres

Tau Decays and Chiral Perturbation Theory

In a small window of phase space, chiral perturbation theory can be used to make standard model predictions for tau decays into two and three pions. For $\tau \to 2\pi \nu_\tau$, we give the analytical result for the relevant form factor $F_V$ up to two loops, then calculate the differential spectrum and compare with available data. For $\tau \to 3 \pi \nu_\tau$, we have calculated the hadronic matrix element to one loop. We discuss the decomposition of the three pion states into partition states and we give detailed predictions for the decay in terms of structure functions. We also compare with low energy predictions of meson dominance models. Overall, we find good agreement, but also some interesting discrepancies, which might have consequences beyond the limit of validity of chiral perturbation theory.Comment: 39 pages, Latex, including 8 Postscript figures. The complete paper is also available via anonymous ftp at ftp://www-ttp.physik.uni-karlsruhe.de/ , or via www at http://www-ttp.physik.uni-karlsruhe.de/cgi-bin/preprint

Quantum corrections for spinning particles in de Sitter

We compute the one-loop quantum corrections to the gravitational potentials of a spinning point particle in a de Sitter background, due to the vacuum polarisation induced by conformal fields in an effective field theory approach. We consider arbitrary conformal field theories, assuming only that the theory contains a large number N of fields in order to separate their contribution from the one induced by virtual gravitons. The corrections are described in a gauge-invariant way, classifying the induced metric perturbations around the de Sitter background according to their behaviour under transformations on equal-time hypersurfaces. There are six gauge-invariant modes: two scalar Bardeen potentials, one transverse vector and one transverse traceless tensor, of which one scalar and the vector couple to the spinning particle. The quantum corrections consist of three different parts: a generalisation of the flat-space correction, which is only significant at distances of the order of the Planck length; a constant correction depending on the undetermined parameters of the renormalised effective action; and a term which grows logarithmically with the distance from the particle. This last term is the most interesting, and when resummed gives a modified power law, enhancing the gravitational force at large distances. As a check on the accuracy of our calculation, we recover the linearised Kerr-de Sitter metric in the classical limit and the flat-space quantum correction in the limit of vanishing Hubble constant

Serum magnesium and calcium levels in relation to ischemic stroke : Mendelian randomization study

ObjectiveTo determine whether serum magnesium and calcium concentrations are causally associated with ischemic stroke or any of its subtypes using the mendelian randomization approach.MethodsAnalyses were conducted using summary statistics data for 13 single-nucleotide polymorphisms robustly associated with serum magnesium (n = 6) or serum calcium (n = 7) concentrations. The corresponding data for ischemic stroke were obtained from the MEGASTROKE consortium (34,217 cases and 404,630 noncases).ResultsIn standard mendelian randomization analysis, the odds ratios for each 0.1 mmol/L (about 1 SD) increase in genetically predicted serum magnesium concentrations were 0.78 (95% confidence interval [CI] 0.69-0.89; p = 1.3 7 10-4) for all ischemic stroke, 0.63 (95% CI 0.50-0.80; p = 1.6 7 10-4) for cardioembolic stroke, and 0.60 (95% CI 0.44-0.82; p = 0.001) for large artery stroke; there was no association with small vessel stroke (odds ratio 0.90, 95% CI 0.67-1.20; p = 0.46). Only the association with cardioembolic stroke was robust in sensitivity analyses. There was no association of genetically predicted serum calcium concentrations with all ischemic stroke (per 0.5 mg/dL [about 1 SD] increase in serum calcium: odds ratio 1.03, 95% CI 0.88-1.21) or with any subtype.ConclusionsThis study found that genetically higher serum magnesium concentrations are associated with a reduced risk of cardioembolic stroke but found no significant association of genetically higher serum calcium concentrations with any ischemic stroke subtype

Topography and temporal evolution of hypoxic viable tissue identified by 18F-fluoromisonidazole positron emission tomography in humans after ischemic stroke

Background and Purpose - We sought to characterize the spatial and temporal evolution of human cerebral infarction. Using a novel method of quantitatively mapping the distribution of hypoxic viable tissue identified by F-18-fluoromisonidazole (F-18-FMISO) PET relative to the final infarct, we determined its evolution and spatial topography in human stroke