Early Svecofennian rift-related magmatism: Geochemistry, U-Pb-Hf zircon isotope data and tectonic setting of the Au-hosting Uunimäki gabbro, SW Finland

We characterise the geochemistry, zircon Lu-Hf composition, age and the structure of the Uunimaki gabbro (UGB) in south-western Finland to improve the understanding of i) the early Svecofennian (1.92-1.89 Ga) crustal evolution of the central Fennoscandian Shield, ii) the potential role of rift-related magmatism for the build-up of the Paleoproterozoic accretionary orogens and iii) evaluate, which geological features provide the primary control over the localization of an orogenic gold mineralisation. The zircon U-Pb geochronology defines an age of 1891 +/- 5 Ma for the UGB, which is slightly older than most mafic intrusions in south-western Finland. The obtained chondritic initial zircon eHf values with E-MORB type geochemical affinity suggest a sub continental lithospheric mantle source for the UGB. The overall geochemistry indicates that the UGB magma as well as other E-MORB type rocks in the Pirkanmaa and Hame belts were formed in a rift-related environment in a fore-arc region at 1.89 Ga, predated by arc-type magmatism at similar to ~1.90 Ga and back-arc magmatism at similar to ~1.92 Ga in the Tampere belt. Slab retreat due to roll-back is suggested to cause the extension and related magmatism in the forearc region. Moreover, the timing and compositional and isotopic changes of early-orogenic magmatism are broadly compatible with intervals of extension and contraction, i.e., a tectonic switching model, and may provide a perspective to rapid build-up of Paleoproterozoic crust. Structural characterisation provides a framework where gold mineralisations are preferentially located within the high-strain north-eastern domain of the UGB, within fracture networks adjoining the high-strain zones. Our results indicate that neither the geochemical composition nor age of the intermediate-mafic intrusive host rocks play a major role in controlling the formation of gold mineralisation. By contrast, the localization of orogenic gold is controlled by localised structures (shear zones, fractures), and the variation in lithological composition of the intrusive host may contribute to the style of the mineralisation.</p

LITHOSPHERE 2018: TENTH SYMPOSIUM ON STRUCTURE, COMPOSITION AND EVOLUTION OF THE LITHOSPHERE: PROGRAMME AND EXTENDED ABSTRACTS

The Uunimäki gabbro was studied by zircon U-Pb geochronology which yielded an age of ~1.89 Ga, making it one of the oldest plutonic rocks in the Häme Belt. Geochemical analysis of the gabbro reveals that it lacks several characteristics for typical subduction zone rocks: (i) it does not have a negative Ta-Nb anomaly compared to average NMORB-composition, (ii) it shows a rather unfractionated REE pattern, (iii) it lacks clear enrichment of fluid-mobile elements (e.g. Ba, Rb, Th, Pb). Structurally, the Uunimäki gabbro is located at the intersection of several regional features: (i) steep NE-plunging folds, (ii) a ENE-WSW-trending deformation zone immediately to the north and (iii) a large N-S-trending deformation zone to the west. The gabbro itself has been deformed under both brittle and ductile conditions by primarily NW-SE-trending faults and shears.</p

LITHOSPHERE 2018: TENTH SYMPOSIUM ON STRUCTURE, COMPOSITION AND EVOLUTION OF THE LITHOSPHERE: PROGRAMME AND EXTENDED ABSTRACTS

Shear zones of various ages and orientations are common in Southern Finland. In the study area, E-W and N-S trending shear zones are the dominant structural feature. Mylonitic foliations were identified from the most intensely sheared rocks. Ductile shearing has mainly been of dip-slip type. Structural mapping revealed several larger map-scale folds, which appear to be relatively continuous across the study area from SE to NW. In the central area, folding interfered with the shear zones causing a complex crustal structure such as associated with the Uunimäki mineralization. Aeromagnetic and lithological maps, field observations, stereographic projections and oriented thin sections were used to determine the structural features of the study area.</p

LITHOSPHERE 2018: TENTH SYMPOSIUM ON STRUCTURE, COMPOSITION AND EVOLUTION OF THE LITHOSPHERE: PROGRAMME AND EXTENDED ABSTRACTS

Field work was conducted in the Kullaa area in SW Finland to study the tectonic evolution and structural setting of the gold mineralisations in the area. Our structural data and interpretation recognises the structural complexity associated with the mineralised zone. We suggest that the NE-SW trending faults in association with the second-order structures related to the NW-SE trending Kynsikangas shear zone have controlled the precipitation of the gold-bearing fluids.</p

Catechol-O-Methyltransferase Gene Polymorphism Is Associated with Skeletal Muscle Properties in Older Women Alone and Together with Physical Activity

Peer reviewe

Metabolic Signatures of Adiposity in Young Adults : Mendelian Randomization Analysis and Effects of Weight Change

Peer reviewe

Common Inflammation-Related Candidate Gene Variants and Acute Kidney Injury in 2647 Critically Ill Finnish Patients

Acute kidney injury (AKI) is a syndrome with high incidence among the critically ill. Because the clinical variables and currently used biomarkers have failed to predict the individual susceptibility to AKI, candidate gene variants for the trait have been studied. Studies about genetic predisposition to AKI have been mainly underpowered and of moderate quality. We report the association study of 27 genetic variants in a cohort of Finnish critically ill patients, focusing on the replication of associations detected with variants in genes related to inflammation, cell survival, or circulation. In this prospective, observational Finnish Acute Kidney Injury (FINNAKI) study, 2647 patients without chronic kidney disease were genotyped. We defined AKI according to Kidney Disease: Improving Global Outcomes (KDIGO) criteria. We compared severe AKI (Stages 2 and 3, n = 625) to controls (Stage 0, n = 1582). For genotyping we used iPLEX(TM) Assay (Agena Bioscience). We performed the association analyses with PLINK software, using an additive genetic model in logistic regression. Despite the numerous, although contradictory, studies about association between polymorphisms rs1800629 in TNFA and rs1800896 in IL10 and AKI, we found no association (odds ratios 1.06 (95% CI 0.89-1.28, p = 0.51) and 0.92 (95% CI 0.80-1.05, p = 0.20), respectively). Adjusting for confounders did not change the results. To conclude, we could not confirm the associations reported in previous studies in a cohort of critically ill patients.Peer reviewe