2,176 research outputs found

    An Evaluation of the Economic, Environmental and Social Impacts of NSW DPI Investments in IPM Research in Invertebrate Rice Pests

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    Research into IPM technologies has been conducted by NSW DPI for over 20 years. Evaluating the returns from investment in specific research and development projects is an important component of the NSW DPI science and research program. An economic evaluation has been conducted of IPM in managing invertebrate pests in rice in NSW. We found that there has been widespread adoption of many IPM practices amongst NSW rice growers leading to a flow of economic benefits to the rice industry and the community. Important environmental and human health benefits were also identified. A benefit-cost ratio of 9.05 was calculated for the return to NSW DPI investment in rice invertebrate pests IPM research. The net present value of the benefits of this research to 2020 was $67.9 million. Important environmental and human health benefits were not valued nor were ‘spillover’ benefits to other States.benefit cost analysis, rice, IPM, invertebrate pests, evaluation, Crop Production/Industries, Environmental Economics and Policy, Farm Management, Production Economics, Q160,

    Autotransporters and Their Role in the Virulence of Burkholderia pseudomallei and Burkholderia mallei

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    Burkholderia pseudomallei and Burkholderia mallei are closely related Gram-negative bacteria responsible for the infectious diseases melioidosis and glanders, respectively. Autotransporters (ATs) comprise a large and diverse family of secreted and outer membrane proteins that includes virulence-associated invasins, adhesins, proteases, and actin-nucleating factors. The B. pseudomallei K96243 genome contains 11 predicted ATs, eight of which share homologs in the B. mallei ATCC 23344 genome. This review distils key findings from in silico, in vitro, and in vivo studies on the ATs of B. pseudomallei and B. mallei. To date, the best characterized of the predicted ATs of B. pseudomallei and B. mallei is BimA, a predicted trimeric AT mediating actin-based motility which varies in sequence and mode of action between Burkholderia species. Of the remaining eight predicted B. pseudomallei trimeric autotransporters, five of which are also present in B. mallei, two (BoaA and BoaB), have been implicated in bacterial adhesion to epithelial cells. Several predicted Burkholderia ATs are recognized by human humoral and cell-mediated immunity, indicating that they are expressed during infection and may be useful for diagnosis and vaccine-mediated protection. Further studies on the mode of secretion and functions of Burkholderia ATs will facilitate the rational design of control strategies

    Efficient coordinate descent for ranking with domination loss

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    Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p. 37-38).We define a new batch coordinate-descent ranking algorithm based on a domination loss, which is designed to rank a small number of positive examples above all negatives, with a large penalty on false positives. Its objective is to learn a linear ranking function for a query with labeled training examples in order to rank documents. The derived single-coordinate updates scale linearly with respect to the number of examples. We investigate a number of modifications to the basic algorithm, including regularization, layers of examples, and feature induction. The algorithm is tested on multiple datasets and problem settings, including Microsoft's LETOR dataset, the Corel image dataset, a Google image dataset, and Reuters RCV1. Specific results vary by problem and dataset, but the algorithm generally performed similarly to existing algorithms when rated by average precision and precision at top k. It does not train as quickly as online algorithms, but offers extensions to multiple layers, and perhaps most importantly, can be used to produce extremely sparse weight vectors. When trained with feature induction, it achieves similarly competitive performance but with much more compact models.by Mark A. Stevens.M.Eng

    A stochastic movement simulator improves estimates of landscape connectivity

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    Acknowledgments This publication issued from the project TenLamas funded by the French Ministère de l'Energie, de l'Ecologie, du Développement Durable et de la Mer through the EU FP6 BiodivERsA Eranet; by the Agence Nationale de la Recherche (ANR) through the open call INDHET and 6th extinction MOBIGEN to V. M. Stevens, M. Baguette, and A. Coulon, and young researcher GEMS (ANR-13-JSV7-0010-01) to V. M. Stevens and M. Baguette; and by a VLIR-VLADOC scholarship awarded to J. Aben. L. Lens, J. Aben, D. Strubbe, and E. Matthysen are grateful to the Research Foundation Flanders (FWO) for financial support of fieldwork and genetic analysis (grant G.0308.13). V. M. Stevens and M. Baguette are members of the “Laboratoire d'Excellence” (LABEX) entitled TULIP (ANR-10-LABX-41). J. M. J. Travis and S. C. F. Palmer also acknowledge the support of NERC. A. Coulon and J. Aben contributed equally to the work.Peer reviewedPublisher PD

    GaAs/GaAlAs distributed Bragg reflector laser with a focused ion beam, low dose dopant implanted grating

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    We report, for the first time, the performance of a GaAs/GaAlAs distributed Bragg reflector (DBR) laser using a focused ion beam implanted grating (FIB‐DBR). Stripes of Si+ + with a period of 2300 Å and a dose ∼1014 cm−2 are directly implanted into the passive large optical cavity layer to provide the distributed feedback. Surface‐emitting light from the second‐order grating is observed. Threshold current of 110 mA and single DBR mode operation from 20 to 40 °C are obtained. The wavelength tuning rate with temperature is 0.8 Å/°C. The coupling coefficient is estimated to be 15 cm−1. The results show that FIB technology is practical for distributed feedback and DBR lasers and optoelectronic integrated circuits

    Phase Coexistence of a Stockmayer Fluid in an Applied Field

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    We examine two aspects of Stockmayer fluids which consists of point dipoles that additionally interact via an attractive Lennard-Jones potential. We perform Monte Carlo simulations to examine the effect of an applied field on the liquid-gas phase coexistence and show that a magnetic fluid phase does exist in the absence of an applied field. As part of the search for the magnetic fluid phase, we perform Gibbs ensemble simulations to determine phase coexistence curves at large dipole moments, μ\mu. The critical temperature is found to depend linearly on μ2\mu^2 for intermediate values of μ\mu beyond the initial nonlinear behavior near μ=0\mu=0 and less than the μ\mu where no liquid-gas phase coexistence has been found. For phase coexistence in an applied field, the critical temperatures as a function of the applied field for two different μ\mu are mapped onto a single curve. The critical densities hardly change as a function of applied field. We also verify that in an applied field the liquid droplets within the two phase coexistence region become elongated in the direction of the field.Comment: 23 pages, ReVTeX, 7 figure

    MHCY haplotype impacts Campylobacter jejuni colonization in a backcross [(Line 61 x Line N) x Line N] population:Research Note

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    MHCY is a candidate region for influencing immune responses in chickens. MHCY contains multiple specialized, polymorphic MHC class I loci along with loci belonging to 4 additional gene families. In this study, MHCY haplotypes were tested for association with cecal colonization after Campylobacter jejuni infection of a backcross [(Line 6(1) × Line N) × Line N] population derived from 2 White Leghorn research lines, Line 6(1) and Line N, that were previously shown to exhibit heritable differences in colonization. Samples were obtained for 51 birds challenged with 10(8) CFU Campylobacter jejuni at 3 wk of age. Viable C. jejuni in the ceca were enumerated 5 d postinfection and counts were log-transformed for analysis. Birds were assigned to either low or high colonization groups based on the individual count being below or above the mean bacterial count for all birds. The mean bacterial count of the low infection group differed significantly from the high infection group. Sex and MHCB haplotype had similar distributions within the 2 groups. Overall, 7 MHCY haplotypes were found to be segregating. Two were significantly associated with C. jejuni colonization. MHCY Y18 was associated with low colonization (P = 3.00 × 10(−5)); whereas MHCY Y11a was associated with high colonization (P = 0.008). The MHCY haplotype impacted the mean bacterial count among all birds with MHCY Y18 having the lowest bacterial count compared with MHCY Y11a and all other MHCY (Y5, Y7, Y8, Y11b, and Y11c) haplotypes. These findings support further investigation of the contribution of chicken MHCY in resistance to Campylobacter colonization
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