79 research outputs found
Scalar dark matter vortex stabilization with black holes
Galaxies and their dark-matter halos are commonly presupposed to spin. But it
is an open question how this spin manifests in halos and soliton cores made of
scalar dark matter (SDM, including fuzzy/wave/ultralight-axion dark matter).
One way spin could manifest in a necessarily irrotational SDM velocity field is
with a vortex. But recent results have cast doubt on this scenario, finding
that vortices are generally unstable except with substantial repulsive
self-interaction. In this paper, we introduce an alternative route to
stability: in both (non-relativistic) analytic calculations and simulations, a
black hole or other central mass at least as massive as a soliton can stabilize
a vortex within it. This conclusion may also apply to AU-scale halos bound to
the sun and stellar-mass-scale Bose stars.Comment: Accepted by JCAP. 22 pages, 5 figures. Supplementary animations at
https://doi.org/10.5281/zenodo.7675830 or
https://www.youtube.com/playlist?list=PLHrf0iQS5SY7Xt2sjqskF3kmHd00Hrdf
Baker Center Journal of Applied Public Policy - Vol. IV, No. I
This is the 4th volume of the Baker Center Journal on Applied Public Policy. It includes articles on nuclear nonproliferation, American political development, election issues, Tennessee state trial courts, attitudes related to rich and poor people, and two student articles on science, innovation, technology and economic growth and explosive trace detection at airports
LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT2A receptor
Compounds that activate the 5-HT2A receptor, such as lysergic acid diethylamide (LSD), act as hallucinogens in humans. One notable exception is the LSD congener lisuride, which does not have hallucinogenic effects in humans even though it is a potent 5-HT2A agonist. LSD and other hallucinogens have been shown to disrupt prepulse inhibition (PPI), an operational measure of sensorimotor gating, by activating 5-HT2A receptors in rats.
We tested whether lisuride disrupts PPI in male Sprague–Dawley rats. Experiments were also conducted to identify the mechanism(s) responsible for the effect of lisuride on PPI and to compare the effects of lisuride to those of LSD.
Confirming a previous report, LSD (0.05, 0.1, and 0.2Â mg/kg, s.c.) reduced PPI, and the effect of LSD was blocked by pretreatment with the selective 5-HT2A antagonist MDL 11,939. Administration of lisuride (0.0375, 0.075, and 0.15Â mg/kg, s.c.) also reduced PPI. However, the PPI disruption induced by lisuride (0.075Â mg/kg) was not blocked by pretreatment with MDL 11,939 or the selective 5-HT1A antagonist WAY-100635 but was prevented by pretreatment with the selective dopamine D2/D3 receptor antagonist raclopride (0.1Â mg/kg, s.c).
The effect of LSD on PPI is mediated by the 5-HT2A receptor, whereas activation of the 5-HT2A receptor does not appear to contribute to the effect of lisuride on PPI. These findings demonstrate that lisuride and LSD disrupt PPI via distinct receptor mechanisms and provide additional support for the classification of lisuride as a non-hallucinogenic 5-HT2A agonist
Autism and the transition to university from the student perspective
University provides individuals with the opportunity to develop greater independence in living skills and social networks, while also gaining valuable qualifications. Despite a high proportion of autistic individuals aspiring to attend university, many either do not seek or gain entry or drop out prematurely. Although some steps have been taken to develop effective support, a recent review highlighted the scarcity of research into programmes designed to support autistic students transitioning to university. In addition, few studies have examined the views of autistic students themselves. This study investigated the perspectives of autistic students transitioning to university. Three focus groups were conducted with 25 autistic students preparing to start university. Participants were asked about their hopes for starting university, as well as their worries and concerns. Data were analysed using thematic analysis, from which five main themes were identified: The Social World, Academic Demands, Practicalities of University Living, Leaving the Scaffolding of Home and Transition to Adulthood. The results provide an important account of the challenges autistic students face when transitioning to university, as well as their aspirations. These findings have a number of practical implications
The dynamics of visual experience, an EEG Study of subjective pattern formation
Background: Since the origin of psychological science a number of studies have reported visual pattern formation in the
absence of either physiological stimulation or direct visual-spatial references. Subjective patterns range from simple
phosphenes to complex patterns but are highly specific and reported reliably across studies.
Methodology/Principal Findings: Using independent-component analysis (ICA) we report a reduction in amplitude
variance consistent with subjective-pattern formation in ventral posterior areas of the electroencephalogram (EEG). The EEG
exhibits significantly increased power at delta/theta and gamma-frequencies (point and circle patterns) or a series of highfrequency
harmonics of a delta oscillation (spiral patterns).
Conclusions/Significance: Subjective-pattern formation may be described in a way entirely consistent with identical pattern
formation in fluids or granular flows. In this manner, we propose subjective-pattern structure to be represented within a
spatio-temporal lattice of harmonic oscillations which bind topographically organized visual-neuronal assemblies by virtue
of low frequency modulation.peer-reviewe
The dynamics of visual experience, an EEG Study of subjective pattern formation
Background: Since the origin of psychological science a number of studies have reported visual pattern formation in the
absence of either physiological stimulation or direct visual-spatial references. Subjective patterns range from simple
phosphenes to complex patterns but are highly specific and reported reliably across studies.
Methodology/Principal Findings: Using independent-component analysis (ICA) we report a reduction in amplitude
variance consistent with subjective-pattern formation in ventral posterior areas of the electroencephalogram (EEG). The EEG
exhibits significantly increased power at delta/theta and gamma-frequencies (point and circle patterns) or a series of highfrequency
harmonics of a delta oscillation (spiral patterns).
Conclusions/Significance: Subjective-pattern formation may be described in a way entirely consistent with identical pattern
formation in fluids or granular flows. In this manner, we propose subjective-pattern structure to be represented within a
spatio-temporal lattice of harmonic oscillations which bind topographically organized visual-neuronal assemblies by virtue
of low frequency modulation
COMPARATIVE ANALYSIS OF TWO COMPUTER-ASSISTED INSTRUCTIONAL LEARNING STRATEGIES: SIMULATED GAMES AND NON-SIMULATED GAMES IN BIOGRAPHY AND BIBLIOGRAPHY--UNITS IN PRINT MEDIA RESOURCES.
Abstract not availabl
Electrophysiological correlates of flicker-induced form hallucinations
Form hallucinations can be reliably induced using temporally modulated light within a specific frequency range (15-30Hz). The neural substrates of such states have yet to be established with certainty. Brain activity of 5 "high responders" was recorded as they completed a visual report paradigm in flickering Ganzfeld (FGF) conditions. Illusory geometric forms were induced via stimulation of the Ganzfeld with rapid and intermittent square-wave light pulses of 3,000 cd/m2 at 15-30Hz. On experiencing a specified target form (point, rectangle, spiral or circle) a left index button press was made to terminate the flicker presentation. A synchronization of activity in the theta (3.5-7Hz) and gamma (30-70Hz) frequency bands reflective of top-down and bottom-up processing respectively may enable the apperception of geometric form
The dynamics of visual experience, an eeg study of subjective pattern formation
Background: Since the origin of psychological science a number of studies have reported visual pattern formation in the absence of either physiological stimulation or direct visual-spatial references. Subjective patterns range from simple phosphenes to complex patterns but are highly specific and reported reliably across studies.
Methodology/Principal Findings: Using independent-component analysis (ICA) we report a reduction in amplitude variance consistent with subjective-pattern formation in ventral posterior areas of the electroencephalogram (EEG). The EEG exhibits significantly increased power at delta/theta and gamma-frequencies (point and circle patterns) or a series of high-frequency harmonics of a delta oscillation (spiral patterns).
Conclusions/Significance: Subjective-pattern formation may be described in a way entirely consistent with identical pattern formation in fluids or granular flows. In this manner, we propose subjective-pattern structure to be represented within a spatio-temporal lattice of harmonic oscillations which bind topographically organized visual-neuronal assemblies by virtue of low frequency modulation
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