Natural history museums as provocateurs for dialogue and debate

Interpretation in natural history museums is generally conservative with methods of collections interpretation barely changed since the first natural history museums were founded. For all the changes undertaken by museums in the last 20 years, sector leaders such as the American Museum of Natural History, the Natural History Museum, London, the National Museum, Prague, Museum fü r Naturkunde, Berlin and the Muséum national d'Histoire naturelle, Paris still operate by connecting objects with facts about their biology. The recent relocation of the Grant Museum of Zoology at University College London has offered the opportunity for the museum to become a space for dialogue and experimentation. The museum, in collaboration with the university, has developed 'social interpretation' designed to engage visitors with controversial questions in life sciences and museum practice. Visitor responses are recorded and used as the basis to plan future work. The paper explores how this form of engagement with visitors might allow natural history museums to add to established methods of interpretation, and Á in a form of co-production with their visitors Á challenge attitudes to scientific knowledge and its development. Thus, the way natural history museums function as sources of knowledge for the public and the 'front line' of biological engagement is potentially changed, based on the responses of museum visitors

Enhancing Museum Narratives: Tales of Things and UCL’s Grant Museum

Emergent mobile technologies offer museum professionals new ways of engaging visitors with their collections. Museums are powerful learning environments and mobile technology can enable visitors to experience the narratives in museum objects and galleries and integrate them with their own personal reflections and interpretations. UCL‟s QRator project is exploring how handheld mobile devices and interactive digital labels can create new models for public engagement, personal meaning making and the construction of narrative opportunities inside museum spaces. The use of narrative in museums has long been recognised as a powerful communication technique to engage visitors and to explore the different kinds of learning and participation that result. Many museums make extensive use of narrative, or storytelling, as a learning, interpretive, and meaning making tool. This chapter discusses the potential for mobile technologies to connect museums to audiences through co-creation of narratives, taking the QRator project as a case study. The QRator project aims to stress the necessity of engaging visitors actively in the creation of their own interpretations of museum collections through the integration of QR codes, iPhone, iPad, and Android apps into UCL‟s Grant Museum of Zoology. Although this chapter will concentrate on mobile technology created for a natural history museum, issues of meaning making and narrative creation through mobile technology are applicable to any discipline. In the first instance, the concern is with the development of mobile media in museums followed by a discussion of the QRator project which stresses the opportunities and challenges in utilizing mobile technology to enhance visitor meaning making and narrative construction. Finally, this chapter discusses the extent to which mobile technologies might be used purposefully to transform institutional cultures, practices and relationships with visitors

Introducing Change in Public Service Organizations under Austerity: The Complex Case of the Governance of the Defence in the United Kingdom

Introducing, managing, and sustaining change in public service organizations is challenging for policy makers to implement and for scholars to theorize. In 2010, the U.K. Government introduced policy changes to help bring down the national deficit. The executive's planned reforms aimed to deliver a so‐called battle‐winning military force, a smaller and more professional Ministry of Defence, and an affordable overall defence organization. The article borrows from theories of management and public policy to help enlighten our understanding of change under New Public Management and governance approaches. The article's central claim is that the U.K. Government sought to correct cost‐efficiency processes in public service organizations trying to reshape organizational and managerial structures dependent on many internal and external pressures. The article examines the executive's purpose in developing a need for change and the ways to implement it. I question whether the U.K. Government's prescriptive and hierarchical approach to organizational change in public administration is sustainable in the long term

Object-based learning and research-based education:Case studies from the UCL curricula

157 Chapter 11 Object-based learning and research-based education: Case studies from the UCL curricula Thomas Kador, Leonie Hannan, Julianne Nyhan, Melissa Terras, Helen J. Chatterjee and Mark Carnall The general broadening in recent years of what counts as legitimate learning has included an interest in objects, including those from curated collections such as artefacts, natural history specimens and archival items, which may have complex cultural or scientific meaning in their own right. A more sophisticated interaction with objects has been a particular focus for some time and meshes well with newer initiatives and strategies. Indeed, it was a forerunner of bringing research-based education into university curricula. These case studies describe how students could be part of genuine research projects while drawing on traditionally neglected aspects of learning such as touch and direct experience. It is no artificial exercise: Kador and his colleagues record that students have at times corrected mistakes in cataloguing, as well as reconsidering the ethics of objects often taken without permission as colonial curiosities. Francis Galton and his colleague Flinders Petrie must be reckoned with again, given the provenance of many of the objects available to UCL students on site. They are also concerned with the opposite direction: creating virtual versions of objects gives students the chance not just to learn, but to ‘produce’, by creating exhibitio

Spectroscopic verification of very luminous galaxy candidates in the early universe

During the first 500 million years of cosmic history, the first stars and galaxies formed and seeded the cosmos with heavy elements. These early galaxies illuminated the transition from the cosmic "dark ages" to the reionization of the intergalactic medium. This transitional period has been largely inaccessible to direct observation until the recent commissioning of JWST, which has extended our observational reach into that epoch. Excitingly, the first JWST science observations uncovered a surprisingly high abundance of early star-forming galaxies. However, the distances (redshifts) of these galaxies were, by necessity, estimated from multi-band photometry. Photometric redshifts, while generally robust, can suffer from uncertainties and/or degeneracies. Spectroscopic measurements of the precise redshifts are required to validate these sources and to reliably quantify their space densities, stellar masses, and star formation rates, which provide powerful constraints on galaxy formation models and cosmology. Here we present the results of JWST follow-up spectroscopy of a small sample of galaxies suspected to be amongst the most distant yet observed. We confirm redshifts z > 10 for two galaxies, including one of the first bright JWST-discovered candidates with z = 11.4, and show that another galaxy with suggested z ~ 16 instead has z = 4.9, with strong emission lines that mimic the expected colors of more distant objects. These results reinforce the evidence for the rapid production of luminous galaxies in the very young Universe, while also highlighting the necessity of spectroscopic verification for remarkable candidates.Comment: Submitted to Natur

The Glycosylphosphatidylinositol-PLC in Trypanosoma brucei Forms a Linear Array on the Exterior of the Flagellar Membrane Before and After Activation

Bloodstream forms of Trypanosoma brucei contain a glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC) that cleaves the GPI-anchor of the variable surface glycoprotein (VSG). Its location in trypanosomes has been controversial. Here, using confocal microscopy and surface labelling techniques, we show that the GPI-PLC is located exclusively in a linear array on the outside of the flagellar membrane, close to the flagellar attachment zone, but does not co-localize with the flagellar attachment zone protein, FAZ1. Consequently, the GPI-PLC and the VSG occupy the same plasma membrane leaflet, which resolves the topological problem associated with the cleavage reaction if the VSG and the GPI-PLC were on opposite sides of the membrane. The exterior location requires the enzyme to be tightly regulated to prevent VSG release under basal conditions. During stimulated VSG release in intact cells, the GPI-PLC did not change location, suggesting that the release mechanism involves lateral diffusion of the VSG in the plane of the membrane to the fixed position of the GPI-PLC

Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial

Background: The EMPA KIDNEY trial showed that empagliflozin reduced the risk of the primary composite outcome of kidney disease progression or cardiovascular death in patients with chronic kidney disease mainly through slowing progression. We aimed to assess how effects of empagliflozin might differ by primary kidney disease across its broad population. Methods: EMPA-KIDNEY, a randomised, controlled, phase 3 trial, was conducted at 241 centres in eight countries (Canada, China, Germany, Italy, Japan, Malaysia, the UK, and the USA). Patients were eligible if their estimated glomerular filtration rate (eGFR) was 20 to less than 45 mL/min per 1·73 m2, or 45 to less than 90 mL/min per 1·73 m2 with a urinary albumin-to-creatinine ratio (uACR) of 200 mg/g or higher at screening. They were randomly assigned (1:1) to 10 mg oral empagliflozin once daily or matching placebo. Effects on kidney disease progression (defined as a sustained ≥40% eGFR decline from randomisation, end-stage kidney disease, a sustained eGFR below 10 mL/min per 1·73 m2, or death from kidney failure) were assessed using prespecified Cox models, and eGFR slope analyses used shared parameter models. Subgroup comparisons were performed by including relevant interaction terms in models. EMPA-KIDNEY is registered with ClinicalTrials.gov, NCT03594110. Findings: Between May 15, 2019, and April 16, 2021, 6609 participants were randomly assigned and followed up for a median of 2·0 years (IQR 1·5–2·4). Prespecified subgroupings by primary kidney disease included 2057 (31·1%) participants with diabetic kidney disease, 1669 (25·3%) with glomerular disease, 1445 (21·9%) with hypertensive or renovascular disease, and 1438 (21·8%) with other or unknown causes. Kidney disease progression occurred in 384 (11·6%) of 3304 patients in the empagliflozin group and 504 (15·2%) of 3305 patients in the placebo group (hazard ratio 0·71 [95% CI 0·62–0·81]), with no evidence that the relative effect size varied significantly by primary kidney disease (pheterogeneity=0·62). The between-group difference in chronic eGFR slopes (ie, from 2 months to final follow-up) was 1·37 mL/min per 1·73 m2 per year (95% CI 1·16–1·59), representing a 50% (42–58) reduction in the rate of chronic eGFR decline. This relative effect of empagliflozin on chronic eGFR slope was similar in analyses by different primary kidney diseases, including in explorations by type of glomerular disease and diabetes (p values for heterogeneity all >0·1). Interpretation: In a broad range of patients with chronic kidney disease at risk of progression, including a wide range of non-diabetic causes of chronic kidney disease, empagliflozin reduced risk of kidney disease progression. Relative effect sizes were broadly similar irrespective of the cause of primary kidney disease, suggesting that SGLT2 inhibitors should be part of a standard of care to minimise risk of kidney failure in chronic kidney disease. Funding: Boehringer Ingelheim, Eli Lilly, and UK Medical Research Council

Chasing the online audience

Museums have engaged with web audiences and web technologies with mixed success. Some careful consideration and analysis of general web browsing trends suggests that in order to enable museums websites to reach a wider audience, online museums should make sure that they are tied into relevant Wikipedia entries on the key themes and figures that a particular museum represents. In addition, translating websites into Asian languages significantly increases the potential global audience by several billion online users. These simple steps dramatically increase the availability of existing content. However, currently, few museums have done either

Cephalopods of the Multiverse

Carnall, M.A. (2018) Cephalopods of the Multiverse. Journal of Geek Studies 5(2): 60-68