39 research outputs found

    Satellite design optimization for differential lift and drag applications

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    Utilizing differential atmospheric forces in the Very Low Earth Orbits (VLEO) regime for the control of the relative motion within a satellite formation is a promising option as any thrusting device has tremendous effects on the mission capacity due to the limited weight and size restrictions of small satellites. One possible approach to increase the available control forces is to reduce the mass of the respective satellites as well as to increase the available surface area. However, satellites of these characteristics suffer from rapid orbital decay and consequently have a reduced service lifetime. Therefore, achieving higher control forces is in contradiction to achieving a minimum orbital decay of the satellites, which currently represents one of the biggest challenges in the VLEO regime. In this work, the geometry of a given reference satellite, a 3UCubeSat, is optimized under the consideration of different surface material properties for differential lift and drag control applications while simultaneously ensuring a sustained VLEO operation. Notably, not only the consideration of sustainability but also the optimization with regard to differential lift is new in literature. It was shown that the advantageous geometries strongly depend on the type of gas-surface interaction and thus, two different final designs, one for each extreme type, are presented. In both cases, improvements in all relevant parameters could be achieved solely via geometry adaptions

    Recurrent neuroendocrine adenoma of the middle ear: A case report

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    Les historiens, qui sont rarement des oiseaux de très bon augure pour la vitalité des croyances qu’ils étudient, ont beaucoup écrit, depuis les années 1970, sur le purgatoire, ce troisième « lieu » de l’au-delà catholique, situé entre enfer et paradis. Support d’une dévotion très populaire, il a connu en Europe trois pics successifs de popularité, à la fin du Moyen Âge, au xviie et au xixe siècles. Le dogme et la croyance ont ainsi puissamment structuré dans la longue durée le rapport aux morts dans les sociétés de culture catholique, en leur conférant une « utilité » particulière, à la fois matérielle, institutionnelle, pastorale et anthropologique, que cet article s’efforce d’explorer.Historians are people who rarely contribute to the continued vitality of the beliefs they study. Since the 1970’s they have written a lot about purgatory, the third place in the catholic beyond. This is situated in between hell and paradise. The belief was the basis of a very popular cult which peaked in popularity in three different periods, one at the end of the Middle Ages, another in the seventeenth and a third in the nineteenth century. The dogma and the belief in purgatory have thus for long periods powerfully structured the relation to the dead in catholic cultures and have given these a particular “usefulness” whether this concerns material, institutional, pastoral or anthropological aspects. The paper attempts to explore these issues

    Molten Salt Thermal Energy Storage Systems

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    The feasibility of storing thermal energy at temperatures of 450 C to 535 C in the form of latent heat of fusion was examined for over 30 inorganic salts and salt mixtures. Alkali carbonate mixtures were chosen as phase-change storage materials in this temperature range because of their relatively high storage capacity and thermal conductivity, moderate cost, low volumetric expansion upon melting, low corrosivity, and good chemical stability. Means of improving heat conduction through the solid salt were explored

    Tracking the Expression of Excitatory and Inhibitory Neurotransmission-Related Proteins and Neuroplasticity Markers after Noise Induced Hearing Loss

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    Excessive exposure to loud noise can damage the cochlea and create a hearing loss. These pathologies coincide with a range of CNS changes including reorganisation of frequency representation, alterations in the pattern of spontaneous activity and changed expression of excitatory and inhibitory neurotransmitters. Moreover, damage to the cochlea is often accompanied by acoustic disorders such as hyperacusis and tinnitus, suggesting that one or more of these neuronal changes may be involved in these disorders, although the mechanisms remain unknown. We tested the hypothesis that excessive noise exposure increases expression of markers of excitation and plasticity, and decreases expression of inhibitory markers over a 32-day recovery period. Adult rats (n = 25) were monaurally exposed to a loud noise (16 kHz, 1/10th octave band pass (115 dB SPL)) for 1-hour, or left as non-exposed controls (n = 5). Animals were euthanased at either 0, 4, 8, 16 or 32 days following acoustic trauma. We used Western Blots to quantify protein levels of GABAA receptor subunit α1 (GABAAα1), Glutamic-Acid Decarboxylase-67 (GAD-67), N-Methyl-D-Aspartate receptor subunit 2A (NR2A), Calbindin (Calb1) and Growth Associated Protein 43 (GAP-43) in the Auditory Cortex (AC), Inferior Colliculus (IC) and Dorsal Cochlear Nucleus (DCN). Compared to sham-exposed controls, noise-exposed animals had significantly (p<0.05): lower levels of GABAAα1 in the contralateral AC at day-16 and day-32, lower levels of GAD-67 in the ipsilateral DCN at day-4, lower levels of Calb1 in the ipsilateral DCN at day-0, lower levels of GABAAα1 in the ipsilateral AC at day-4 and day-32. GAP-43 was reduced in the ipsilateral AC for the duration of the experiment. These complex fluctuations in protein expression suggests that for at least a month following acoustic trauma the auditory system is adapting to a new pattern of sensory input

    Recent developments in genetics and medically assisted reproduction : from research to clinical applications

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    Two leading European professional societies, the European Society of Human Genetics and the European Society for Human Reproduction and Embryology, have worked together since 2004 to evaluate the impact of fast research advances at the interface of assisted reproduction and genetics, including their application into clinical practice. In September 2016, the expert panel met for the third time. The topics discussed highlighted important issues covering the impacts of expanded carrier screening, direct-to-consumer genetic testing, voiding of the presumed anonymity of gamete donors by advanced genetic testing, advances in the research of genetic causes underlying male and female infertility, utilisation of massively parallel sequencing in preimplantation genetic testing and non-invasive prenatal screening, mitochondrial replacement in human oocytes, and additionally, issues related to cross-generational epigenetic inheritance following IVF and germline genome editing. The resulting paper represents a consensus of both professional societies involved.Peer reviewe
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