Polycystic ovary syndrome therapeutic methods: A systematic review

Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disorder, whose prevalence in women varies from 6 to 10% in the reproductive period. It can lead to health complications, such as menstrual dysfunction, infertility, hirsutism, acne and metabolic syndrome. The biggest difficulties with this syndrome is to recognize its etiopathogenesis and select the best therapy. This study is a systematic review, which carried out an electronic search in the following databases SCIELO, LILACS, PUBMED, selected 34 articles. The purpose of the review is: to understand the therapeutic methods available for treatment, although there is no cure for the syndrome, the aim of the approach is to minimize the clinical signs and improve the quality of life of these women. The first therapy to be used is the change in lifestyle and changes in the diet, in the background medications are applied. Treatment must be individualized according to the complaints of each patient

Estratégias de Employer Branding com enfoque na retenção de colaboradores: estudo aplicado em uma empresa de tecnologia de Florianópolis

TCC (graduação) - Universidade Federal de Santa Catarina, Centro Sócio Econômico, Administração.Este estudo aplicado objetiva a análise de como implementar estratégias de Employer Branding em uma empresa de tecnologia da grande Florianópolis, visando a retenção de colaboradores. Para atingir o objetivo da pesquisa foi realizado um estudo descritivo e explicativo através da abordagem do conceito de Employer Branding e aplicação de questionários a fim de entender as atuais práticas da empresa, por meio das percepções da gestão, dos colaboradores e de ex-colaboradores. Para a análise entre as percepções coletadas, utilizou-se a distribuição percentual dos dados pelas categorias, cálculo de incidência nas respostas, correlações expressas pelo coeficiente de Pearson, além de reflexão de conteúdo. Houve um alto percentual de concordância com a cultura da empresa nas três coletas, porém demonstrou-se uma diversificação nos percentuais de concordância nas outras categorias. Os resultados mostraram desalinhamentos relevantes entre os colaboradores atuais e ex colaboradores, além do desencontro entre a necessidade atual da empresa e o que é praticado pela mesma, refletindo em uma marca empregadora mais fragilizada do que se imaginava. Assim sendo, a empresa objeto deste estudo tem como oportunidade utilizar as sugestões deste estudo para mudar a sua realidade.This study aims to analyze how to implement Employer Branding strategies focusing on employee retention at a technology company based in Florianópolis. To achieve the research objective, a descriptive and explanatory research started with different employer branding approaches and went through a questionnaire application in order to understand the current practices at the company. The questionnaire was answered through 3 different perspectives: company and management perceptions, employees perceptions and former employees perceptions. The analysis between all the perceptions was done by statistical methods as percentage distribution of data by categories, incidence of answers, correlations expressed by Pearson coefficient and authors conclusions on theory and data. A high percentage of agreement about the company's culture was found at all perspectives, meanwhile other categories did not present many matches, weakening the employer brand. The results showed relevant misalignments between current employees and former employees, in addition to the mismatch between the current need of the company and what is practiced by the company. This scenario reflects on a more fragile employer brand than imagined. Therefore, the company object of this study has the opportunity to use the suggestions of this study to change its reality

Editorial

Editorial da Edição Zero da Revista Epígrafe

Resistência de linhagens de feijoeiro-comum a isolados de Sclerotinia sclerotiorum em diferentes condições ambientais

The objective of this work was to evaluate the reaction of common bean (Phaseolus vulgaris) lines to Sclerotinia sclerotiorum, the aggressiveness of the isolates, and the inheritance of resistance to white mold, under two environmental conditions. The experiments were carried out under field and greenhouse conditions. In each one, four isolates were inoculated in 14 common bean lines using the straw-test inoculation method and severity on plants. No common bean line with a high level of resistance to white mold was identified, and most of the lines were moderately resistant to the pathogen. In general, the BRS Campeiro, BRS Radiante, BRSMG Talismã, and Ouro Negro cultivars stand out for resistance. Under field conditions, the UFLA 3 isolate discriminates well the lines, while, under greenhouse conditions, UFLA 26 and UFLA 92 are the most aggressive isolates. Furthermore, according to the genetic study, most of the observed variation can be attributed to horizontal resistance, although a small part is associated with vertical resistance.O objetivo deste trabalho foi avaliar a reação de linhagens de feijoeiro (Phaseolus vulgaris) ao fungo Sclerotinia sclerotiorum, a agressividade dos isolados, e a herança de resistência ao mofo-branco, em duas condições ambientais. Os experimentos foram realizados em condições de campo e casa de vegetação. Em cada um deles, quatro isolados foram inoculados em 14 linhagens de feijoeiro-comum pelo método de inoculação “straw test” e a severidade nas plantas foi avaliada. Não se identificaram linhagens de feijão-comum com alto nível de resistência ao mofo-branco, e a maioria delas mostrou-se moderadamente resistente ao patógeno. Em geral, as cultivares BRS Campeiro, BRS Radiante, BRSMG Talismã e Ouro Negro destacam-se quanto à resistência. Na condição de campo, o isolado UFLA 3 discrimina bem as linhagens, enquanto, na casa de vegetação, UFLA 26 e UFLA 92 são os isolados mais agressivos. Além disso, de acordo com o estudo genético, a maior parte da variação encontrada pode ser atribuída à resistência horizontal, embora uma pequena parte esteja associada à resistência vertical

Chemodectoma in a Bitch

Background: Chemodectomas, better known as tumors of the base of the heart, arise from aortic bodies, respiratory chemoreceptors located near or inside the aortic arch or originate from receptors located in the carotid arteries. Relatively rare, they affect dogs and, to a lesser extent, felines. They gain great importance when they influence the function of the cardiovascular system, with animals showing clinical signs related to congestive heart failure. Clinical diagnosis is based on symptomatology and complementary tests such as radiography, electrocardiography and echocardiography, while the definitive diagnosis is obtained by cytological and histopathological exams. This study aims to reports a case of malignant chemodectoma in a bitch, whose main symptomatology was neurological and not cardiovascular. Case: A 1-year-old Rottweiler bitch was attended with neurological alterations compatible with vestibular syndrome, hyporexia, dysphagia, apathy, melena, emesis, and purulent nasal discharge on the right nostril. On physical examination, the animal showed depressed level of consciousness, poor body condition, bilateral quemosis, paralysis of the right eye, inspiratory dyspnea and muffling of cardiac auscultation, besides a subcutaneous nodule between the scapulae. On neurological evaluation, horizontal nystagmus, head tilt to the right side, ventromedial strabismus and facial nerve paralysis on the right side were observed so that the localization of the lesion was set in peripheral vestibular system. During anesthesia for esophageal tube placement, a mass from the hard palate to the oropharynx was noted, making endotracheal intubation impossible to perform. Biopsy of this nodule was performed, and tracheostomy was indicated, but the owner opted for euthanasia before the procedure. Necropsy revealed white soft masses in the bilateral retromandibular region, on the subcutaneous tissue near the scapulae, in the right ear and since nasopharynx to the soft palate, in addition to sparse white nodules in the heart, lung, carotid artery, kidneys, right ovary, mesentery near to the spleen, and axillary lymph node. Histologically, the nodules were characterized by neoplastic cells population organized in short bundles or cords, arranged around small blood vessels surrounded by delicate connective tissue. Neoplastic cells infiltrated muscles and blood and lymphatic vessels were filled by multiple neoplastic emboli. The histological pattern of the cells allowed the diagnosis of chemodectoma. Discussion: The bitch from this case had 1-year-old when diagnosed with chemodectoma, differently from most cases from literature, that are between 7 to 15 years old. Furthermore, primarily cardiac tumors are considered rare, being chemodectoma the most common, often reported in Boxer and Boston Terrier dogs, but unusual in Rottweilers. Despites some articles mentioning seizure and Horner Syndrome secondary to a carotid body chemodectoma, neurological signs are not commonly observed in these cases. The presence of the tumor in the middle ear region of the right side supports the occurrence of peripheral vestibular syndrome and facial nerve paralysis on the same side. Because it is a neoplasm that is usually detected late during the course of the disorder, most patients either cannot obtain diagnosis in vivo, as in this reported animal, which was in such a critical condition that underwent euthanasia, or there are no more possible therapeutic choices. In the patient described, there were numerous metastatic masses and nodules spread throughout the body. Although the typical clinical signs in animals with chemodectomas are often related to heart disease, neurological signs may also be present. This report emphasizes the importance of chemodectoma being included as a differential diagnosis in young dogs and even in breeds such as Rottweiler. Keywords: aortic body neoplasia, paraganglioma, vestibular syndrome

Afetos, significados e sentidos relacionados com o ambiente escolar para estudantes do Ensino Médio

This article aims to analyze theaffections, meanings and perceptions of the school environment for young students from a public school in Fortaleza, Brazil, from the perspective of Historical-Cultural Theory and Environmental Psychology. Such analysis considers, therefore, the person-environment relations as generators of a mutuality of affections that interfere in the way young people think, feel, perceive and behave in the school space. This affectation causes changes in the interrelations that occur between young students and the educational environment, favoring participation, involvement or withdrawal from school. 42 young people from the 2nd year of high school participated in the qualitative research, and the Generating Affective Maps Instrument (IGMA) was used for data collection. The results indicated that students internalize social meanings about the school environment as if they were their own senses; the affections unveiled about this place are ambiguous, contrasting happiness and/or prejudice; the school is a place of interrelationships that affect and transform the person as well as the environment, in addition to being a place for projecting dreams and expectations, perspectives and preparation for the future.Este artículo tiene como objetivo analizar los significados, sentidos y afectos del ambiente escolar para jóvenes estudiantes de una escuela pública de Fortaleza Ceará, Brasil, desde la perspectiva de la teoría histórico-cultural y la . Dicho análisis considera, por tanto, las relaciones persona-ambiente como generadoras de una reciprocidad de afectos que interfieren en la forma cómo los jóvenes piensan, sienten, perciben y se comportan en el espacio escolar. Esta afectación provoca cambios en las interrelaciones que se producen entre los jóvenes estudiantes y el ambiente educativo, favoreciendo la participación, el involucramiento o el retiro de la escuela. En la investigación cualitativa participaron 42 jóvenes de 2º año de bachillerato y, para la recolección de datos, se utilizó el Instrumento Generador de Mapas Afectivos (IGMA). Los resultados indicaron que los estudiantes internalizan los significados sociales sobre el ambiente escolar como si fueran sus propios sentidos; los afectos que se desvelan sobre ese sitio son ambiguos, contrastando entre la felicidad y/o el daño;se evidenció, todavía, la escuela como un sitio de interrelaciones que afectan y transforman a la persona y el entorno y que influyen en el proceso de proyección de sueños y expectativas, perspectivas y preparación para el futuro.O presente artigo tem como objetivo analisar os afetos, significados e sentidos do ambiente escolar para jovens estudantes de uma escola pública de Fortaleza/CE sob a perspectiva da teoria histórico-cultural e da. Essa análise considera, portanto, as relações pessoa-ambiente enquanto geradoras de uma mutualidade de afetos que interferem no modo como os jovens pensam, sentem, percebem e se comportam no espaço escolar. Essa afetação provoca transformações nas inter-relações que ocorrem entre os jovens estudantes e o ambiente educacional, favorecendo a participação, o envolvimento ou o afastamento da escola. Participaram da pesquisa de enfoque qualitativo 42 jovens do 2º ano do ensino médio e, para a coleta de dados, utilizou-se o Instrumento Gerador dos Mapas Afetivos (IGMA). Os resultados indicaram que os estudantes internalizam os significados sociais a respeito do ambiente escolar como se fossem seus próprios sentidos; os afetos desvelados sobre tal lugar são ambíguos, contrastando entre felicidade e/ou prejuízo;evidenciou-se, ainda, a escola como lugar de inter-relações que afetam e transformam a pessoa e o ambiente e que influenciam o processo de projeção de sonhos e expectativas, de perspectivas e de preparação para o futuro

High level of serovar copenhageni detection in dog sera from Patrocínio, MG, Brazil

T This study aimed to evaluate the occurrence of canine leptospirosis and the possible risk factors associated with the disease in the municipality of Patrocínio, MG, Brazil. A cross-sectional observational study was carried out from July through August 2017.  The municipality was divided into four regions (north, south, east and west) and a predefined number of neighborhoods (25) were randomly sampled in each region. Samples of blood serum were collected from 241 domiciled male and female dogs of different breeds and ages. To investigate the risk factors for canine leptospirosis, the owners of the animals were asked to fill out an epidemiological questionnaire. The following factors were evaluated: breed, sex, age, presence of rodents, type of diet, access to the street, vaccination, presence of flooded areas, and educational level of the owners. Blood serum samples were evaluated by the Microscopic Agglutination Test (MAT), using a collection of 24 live antigens. Of the 241 dogs evaluated, 32 (13.2%) were reactive. The most frequent serovars were: Copenhageni (37.5%) and Canicola (21.8%), followed by Icterohaemorrhagiae and Grippotyphosa (12.5%), Pomona, Tarassovi and Butembo (9.3%) and Hardjo (6.2%). The presence of canine leptospirosis was associated with purebred dogs (OR=0.3059 [95% CI: 0.1430 – 0.6547]) and vaccination (OR=2.581 [95% CI: 1.198 – 5.563]). It was concluded that some dogs in the municipality of Patrocínio, MG have anti-Leptospira spp. antibodies and that the serovars most frequently identified were Copenhageni (37.5%) and Canicola (21.8%). Pure breeds and vaccination were factors associated with the prevalence of infection