248 research outputs found

    Coding Dojo: An Environment for Learning and Sharing Agile Practices

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    A Coding Dojo is a meeting where a group of program-mers gets together to learn, practice, and share experiences. This report describes the authors ’ experience of creating and running an active Coding Dojo in São Paulo, Brazil, sharing the lessons learned from the experience. The role of the Dojo in the learning process is discussed, showing how it creates an environment for fostering and sharing Ag-ile practices such as Test-Driven Development, Refactoring and Pair Programming, among others.

    Study of the removal capacity of 2-MIB and geosmin by nanofiltration membranes pretreated in water and 50% (v/v) aqueous ethanol solution

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    Membranas de nanofiltração apresentam elevada eficácia na remoção de compostos de baixa massa molar, o que inclui os metabólitos secundários 2-metilisoborneol (2-MIB) e 1,10-dimetil trans-9-decalol (Geosmina), produzidos por cianobactérias e de difícil remoção por processos convencionais de tratamento. Considerando-se que elevada retenção e fluxo permeado são características importantes no processo, este estudo teve por objetivo avaliar a eficiência da membrana NF90 pré-tratada com água e solução de etanol 50% (v/v) na retenção de 2-MIB e Geosmina, considerando-se a aplicação de baixas pressões constantes de trabalho 4, 7 e 10 bar, avaliando-se a sua permeabilidade à água e capacidade de retenção dos metabólitos. A retenção foi avaliada com a concentração de 100 ng L-1 de 2-MIB e Geosmina por 120 minutos de tempo de filtração. A ocorrência de fouling foi igualmente avaliada constatando-se não haver incrustação. Nas três pressões empregadas, membranas pré-tratadas em solução de etanol 50% (v/v) apresentaram um fluxo permeado superior (91,4 L m-2 h-1 a 225,4 L m-2 h-1) ao observado para membranas tratadas em água (34,08 L m-2 h-1 a 59,14 L m-2 h-1). Quanto à retenção, não foram observadas diferenças expressivas entre as membranas, tendo-se obtido remoções de 93 e 99% para membranas pré-tratadas em solução de etanol 50% (v/v) e água, respectivamente. Pode-se observar que o pré-tratamento conservou a eficiência na retenção de compostos e propiciou a melhoria das características físicas e químicas da membrana, permitindo a obtenção de fluxos permeados maiores do que o observado com a membrana pré-tratada em água.Nanofiltration membranes are highly effective in removing low-molecular weight compounds, which include the secondary metabolites 2-methylisoborneol (2-MIB) and 1,10-dimethyl trans-9-decalol (Geosmin), produced by cyanobacteria and difficult to remove by conventional treatment processes. Considering that high retention and permeate flux are important characteristics in the process, this study aimed to evaluate the efficiency of the NF90 membrane pretreated with water and 50% (v/v) ethanol solution in the retention of 2-MIB and Geosmin, considering the application of low constant working pressure values of 4, 7, and 10 bar and evaluating its permeability to water and metabolite retention capacity. Retention was evaluated from a concentration of 100 ng L−1 of 2-MIB and Geosmin for 120 min of filtration time. The occurrence of fouling was also evaluated, noting that there was no fouling. At the three pressure values considered, membranes pretreated in 50% (v/v) ethanol solution showed a higher permeate flux (91.4 L m-2 h-1 at 225.4 L m-2 h-1) than that observed for membranes treated in water (34.08 L m-2 h-1 at 59.14 L m-2 h-1). As for retention, no significant differences were observed between the membranes, with removals of 93 and 99% being obtained for membranes pretreated in 50% (v/v) ethanol solution and water, respectively. It can be observed that the pretreatment conserved the efficiency in the retention of compounds and provided an improvement in the physical and chemical characteristics of the membrane, allowing the achievement of permeate fluxes greater than those observed with the membrane pretreated in water

    Práticas alimentares atuais e pregressas em mulheres recuperadas da anorexia nervosa: uma abordagem qualitativa

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    OBJECTIVE: The aim of this study was to analyze qualitatively how women, who have recovered from anorexia nervosa, perceive and describe their current eating practices, as well as the ones developed during the eating disorder period. METHODS: Seven women were interviewed individually with the objective of investigating their eating practices, transition phases and all relevant aspects that somewhat contributed to the habit-forming; experiences, feelings and perceptions related to mealtime and the influence that food has had over the present subjects' life. The interviews were analyzed by the discourse of the collective subject method. RESULTS: The results brought up the following topics: a) control; b) concerns and feelings; c) deprivation d) beauty dictatorship; e) eating competence; f) importance of food; g) food cacophony. CONCLUSIONS: What stands out is a multiplicity of eating practices, which during the eating disorder were similar to and characterized by restriction; however, after recovery, part of the subjects seem to have developed a higher eating competence, whereas others show a practice similar to the one acquired during the anorexia nervosa, such as the difficulty in realizing when they are satisfied and a feeling of discomfort when facing social interactions.OBJETIVO: Este artigo teve como objetivo analisar qualitativamente como mulheres que se recuperaram da anorexia nervosa percebem e relatam suas práticas alimentares atuais, bem como as práticas vigentes no período do transtorno. MÉTODOS: Foram feitas sete entrevistas individuais com mulheres que vivenciaram a anorexia nervosa. Estas abordaram: hábitos alimentares das entrevistadas; mudanças e fatores importantes para a formação destes; vivências, sentimentos e percepções associados ao momento da refeição; e a influência que a alimentação exerce na vida das participantes hoje. A análise dessas deu-se a partir da técnica do Discurso do Sujeito Coletivo. RESULTADOS: Os resultados trouxeram os seguintes temas: a) controle; b) preocupações e sensações; c) privação d) ditadura da beleza; e) competência alimentar; f) importância da alimentação; g) cacofonia alimentar. CONCLUSÕES: Destaca-se nesses a multiplicidade das práticas alimentares, que durante o transtorno se assemelham e se caracterizam pela restrição; no entanto, após a recuperação dos sujeitos, alguns parecem ter desenvolvido maior competência alimentar, enquanto outros apresentam práticas semelhantes às vigentes na anorexia nervosa, além de dificuldade de perceberem quando estão satisfeitos e sensação de desconforto em situações de interação social.Universidade Federal de São Paulo (UNIFESP) Campus Baixada SantistaUniversidad Nacional de Buenos Aires Facultad de Filosofía y Letras Cátedra de AntropologiaUNIFESP, Campus Baixada SantistaSciEL

    O ENSINO DE LÍNGUA PORTUGUESA NO ISOLAMENTO/DISTANCIAMENTO SOCIAL:ADAPTAÇÕES E INOVAÇÕES

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    Este é trabalho de Análise do Discurso que lida com a universalidade da língua, com os movimentos de seus significados e reflete a respeito da influência da linguagem sobre a ideologia e  sua manifestação na e pela língua, cujo corpus é constituído por enunciados oficiais em cadeia (Portarias, Resoluções e Nota Técnica) que, como uma corrente, materializam os discursos regulamentadores o ensino durante a pandemia COVID 19, no Instituto Federal de Goiás – Senador Canedo . Com objetivo de observar o efeito da pandemia no referido processo, realiza-se um Trajeto Temático - narração de fatos analisando as escolhas e efeitos de sentido das palavras, considerando que os discursos que circulam em lugar e momento determinados - permitindo descortinar a situação histórica dada.  Observa-se a emersão de novos termos para se atingir um efeito de sentido específico como Ensino Remoto Emergencial (ERE). Em função de sua assimetria com o termo EaD, eles são socialmente impedidos de serem utilizados de um em substituição ao outro. A retomada histórica permite acionar a memória discursiva pela composição do corpus, vozes oficiais tanto do governo federal quanto da instituição - IFG. A análise das vozes oficiais permite observar que outras medidas pedagógicas foram tomadas como: redução de carga horária de aulas online semanais, flexibilização dos 100 dias letivos no ano calendário 2020 e adoção de novo formato de estágio para menores. No entanto, nesta corrente de enunciados não há enunciados específicos em relação ao ensino/aprendizagem língua portuguesa, em ambiente virtual. Desta forma, aponta-se a possibilidade de que outra pesquisa especificamente direcionada à análise das alterações do ensino de Língua Portuguesa seja realizada, uma vez que as adaptações e inovações apreendidas foram referentes a todas as disciplinas, por meio de entrevistas (caráter dialogal) ou questionário aplicados aos docentes e discente da Língua Portuguesa

    Development and characterization of photoprotective formulations containing keratin particles

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    This work deals with development and evaluation of MFQ protective formulation, which contains two organic filters, namely: octyl-p-methoxycinnamate (OMC) and benzophenone-3 (BP-3); a photostabilizing agent called ethylhexylmethoxycrylene (EHMCR) and keratin particles. The MFQ formulation was evaluated in order to measure its pH, spin-spin lattice relaxation time (T2H), occlusivity factor, formulation efficacy, photostability and skin permeation, as well as keratin particle properties. Keratin particle size increased when incorporated to formulation, however, it did not affect pH. The MFQ formulation was found to be photostable and photoprotective, as evidenced by sunlight photostability test, sun protection factor (SPF), UVA/UVB ratio and critical wavelength. Interaction between keratin particles and active substances (OMC, BP-3 and EHMCR) was evidenced by T2H measurements. Evidences suggest that keratin reduces the permeation of both UV filters employed along this study, therefore, it can be stated that keratin has a promising potential for use in sunscreen formulations

    Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction

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    The protein tau and its isoforms are associated with several neurodegenerative diseases, many of which are characterized by greater deposition of the 4-repeat (4R) tau isoform; however, the role of 4R tau in disease pathogenesis remains unclear. We created antisense oligonucleotides (ASOs) that alter the ratio of 3R to 4R tau to investigate the role of specific tau isoforms in disease. Preferential expression of 4R tau in human tau-expressing (hTau-expressing) mice was previously shown to increase seizure severity and phosphorylated tau deposition without neuronal or synaptic loss. In this study, we observed strong colocalization of 4R tau within reactive astrocytes and increased expression of pan-reactive and neurotoxic genes following 3R to 4R tau splicing ASO treatment in hTau mice. Increasing 4R tau levels in primary astrocytes provoked a similar response, including a neurotoxic genetic profile and diminished homeostatic function, which was replicated in human induced pluripotent stem cell-derived (iPSC-derived) astrocytes harboring a mutation that exhibits greater 4R tau. Healthy neurons cultured with 4R tau-expressing human iPSC-derived astrocytes exhibited a higher firing frequency and hypersynchrony, which could be prevented by lowering tau expression. These findings support a potentially novel pathway by which astrocytic 4R tau mediates reactivity and dysfunction and suggest that astrocyte-targeted therapeutics against 4R tau may mitigate neurodegenerative disease progression

    Reheating and turbulence

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    We show that the ''turbulent'' particle spectra found in numerical simulations of the behavior of matter fields during reheating admit a simple interpretation in terms of hydrodynamic models of the reheating period. We predict a particle number spectrum nkkαn_{k}\propto k^{-\alpha} with α2\alpha \sim 2 for k0.k\to 0.Comment: 10 pages, one figure included in tex

    Cross-cultural adaptation of the State and Trait Food Cravings Questionnaires ( FCQ-S and FCQ-T) into Portuguese

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    This study aimed to present the cross-cultural adaptation of the State and Trait Food Cravings Questionnaires (FCQ-S and FCQ-T) into Portuguese. Tools were translated and back-translated, field experts evaluated the conceptual, operational and item-based equivalence and a sample of students assessed tools, evaluating the level of understanding and analyzing internal consistency through Cronbach's coefficient. In addition, the semantic equivalence was assessed though the intraclass correlation coefficient between the bilingual scores in each question of both versions (English and Portuguese). Tools were considered easy to understand (experts scored 95.4% and 97% for the FCQ-T and FCQ-S, respectively, and 81.8% of students considered them easy to understand), and showed satisfactory internal consistency values (FCQ-T ranged from 0.6 to 0.8 and FCQ-S ranged from 0.5 to 0.8). From the cross-cultural adaptation process, the satisfactory results enable the recommendation of the Brazilian version of FCQs.Univ Sao Paulo, Dept Nutr, Fac Saude Publ, Av Dr Arnaldo 715, BR-01246904 Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Inst Saude & Soc, Sao Paulo, SP, BrazilUniv Sao Paulo, Escola Educ Fis & Esporte, Sao Paulo, SP, BrazilUniv Estadual Campinas, UNICAMP, Fac Ciencias Aplicadas, Limeira, SP, BrazilUniv Estadual Campinas, Fac Educ Fis, Campinas, SP, BrazilUniv Fed Sao Paulo, Inst Saude & Soc, Sao Paulo, SP, BrazilWeb of Scienc
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