Social Representations of Protest and Police after the Genoa G8 Summit: A Qualitative Analysis of Activist Accounts of Events

The Genoa G8 Summit was marred by violence and conflicts between police and activists. Afterwards, these different groups constructed clashing discourses about the events. In turn, these discourses sustained different types of social representations about the nature of the conflict. Earlier analyses of hegemonic social representation examining the Italian press suggested that non-violent activists were subject to processes of delegitimisation and that they were identified with black bloc activists (Cristante, 2003; Juris, 2005; Zamperini & Botticini, 2006). Conversely, in this study we analyze activists\u2019 accounts of the protest and of the violent police repression. We examine a collection of published texts (N= 223) posted on a \u201ccyber-wall\u201d online as part of a collaborative project from three Italian media outlets: Il Manifesto, Radio Popolare, Carta. These texts represent a form of \u201ccounter-narrative\u201d produced by a stigmatized group to contest the dominant discourse, creating a tripartite of relations between non-violent activists, police and the black bloc . The analysis of these texts shows that activists represent the protest as a battle between two groups. Activists describe police as coercive, incompetent, and as the enemy. While the black bloc was perceived to have damaged the protest they were not depicted as the enemy. Cognitive, emotive and behavioral factors associated with these representations are highlighted and discussed, together with the implications for future intergroup relations between activists and the police

Dealing naturally with stumbling blocks on highways and byways of TRAIL induced signaling.

In-depth analysis of how TRAIL signals through death receptors to induce apoptosis in cancer cells using high throughput technologies has added new layers of knowledge. However, the wealth of information has also highlighted the fact that TRAIL induced apoptosis may be impaired as evidenced by experimental findings obtained from TRAIL resistant cancer cell lines. Overwhelmingly, increasing understanding of TRAIL mediated apoptosis has helped in identifying synthetic and natural compounds which can restore TRAIL induced apoptosis via functionalization of either extrinsic or intrinsic pathways. Increasingly it is being realized that biologically active phytochemicals modulate TRAIL induced apoptosis, as evidenced by cell-based studies. In this review we have attempted to provide an overview of how different phytonutrients have shown efficacy in restoring apoptosis in TRAIL resistant cancer cells. We partition this review into how the TRAIL mediated signaling landscape has broadened over the years and how TRAIL induced signaling machinery crosstalks with autophagic protein networks. Subsequently, we provide a generalized view of considerable biological activity of coumarins against a wide range of cancer cell lines and how coumarins (psoralidin and esculetin) isolated from natural sources have improved TRAIL induced apoptosis in resistant cancer cells. We summarize recent updates on piperlongumine, phenethyl isothiocyanate and luteolin induced activation of TRAIL mediated apoptosis. The data obtained from pre-clinical studies will be helpful in translation of information from benchtop to the bedside

Indications to hospital admission and isolation of children wish possibile or defined tuberculosis: systematic review and proposed recommendations for pediatric patients leaving in developed countries.

Tuberculosis (TB) is a re-emerging health problem in developed countries. This paper is part of large guidelines on the global management of TB in children, by a group of scientific societies. It describes the indications to hospitalization of children with suspected or diagnosed TB, the isolation measures, hospital discharge, and re-admission into the community. Using the Consensus Conference method, relevant publications in English were identified by means of a systematic review of MEDLINE and the Cochrane Database of Systematic Reviews from their inception until 31 December 2014. Available data on indications to hospitalization were mainly indirect and largely derived from observational studies. They include: (1) host-related risk factors, the main being age <12 months, immune deficiencies, and malnutrition; (2) TB-related clinical conditions that resemble those of pneumonia but also include drug-resistance; and (3) social and logistic conditions. The latter are based on opinion and depend on local conditions. Analysis of the literature showed that patients hospitalized with suspected pulmonary TB should be put in precautionary respiratory isolation regardless of their age while they await diagnosis. The general conditions for re-admission into the community are at least 14 days of effective treatment and negative microscopic tests of 3 consecutive samples in previously microscopically positive patients. This is the first paper that provides indications to hospitalization of children with TB. Most recommendations are generally applicable in all developed countries. Some might need an adaptation to local setting, epidemiological, parameters, and availability of specific health-care facilities

Plasticity of Repetitive DNA Sequences within a Bacterial (Type IV) Secretion System Component

DNA rearrangement permits bacteria to regulate gene content and expression. In Helicobacter pylori, cagY, which contains an extraordinary number of direct DNA repeats, encodes a surface-exposed subunit of a (type IV) bacterial secretory system. Examining potential DNA rearrangements involving the cagY repeats indicated that recombination events invariably yield in-frame open reading frames, producing alternatively expressed genes. In individual hosts, H. pylori cell populations include strains that produce CagY proteins that differ in size, due to the predicted in-frame deletions or duplications, and elicit minimal or no host antibody recognition. Using repetitive DNA, H. pylori rearrangements in a host-exposed subunit of a conserved bacterial secretion system may permit a novel form of antigenic evasion

N=1/2 gauge theory and its instanton moduli space from open strings in R-R background

We derive the four dimensional N=1/2 super Yang-Mills theory from tree-level computations in RNS open string theory with insertions of closed string Ramond-Ramond vertices. We also study instanton configurations in this gauge theory and their ADHM moduli space, using systems of D3 and D(-1) branes in a R-R background.Comment: 29 pages, 6 figures, JHEP class (included