Sex-specific percentiles for bodyweight and height in children born with esophageal atresia : a registry-based analysis 2001–2021

Background Esophageal atresia (EA) is a rare malformation with a wide range of co-morbidity and associated malformations impairing weight gain and growth. The aim of this study was to calculate specific percentiles for body weight and height for children born with esophageal atresia according to sex from birth to the age of 6 years, accounting for prematurity and presence of congenital heart disease (CHD). Methods Data was extracted from an anonymized voluntary national registry for patients born with esophageal atresia between 2001 and 2021, from birth until the age of six years. Missing values were imputed using a multiple imputation approach. In premature infants, chronological age was corrected for gestational week until the age of one year. The impact of sex and additional congenital heart disease on weight gain and growth was analysed using quartile regression models. Results In total, 1812 examinations of 485 patients were considered and 1232 examinations of 301 patients were finally included. Most data was available for children at birth and during the first year of life. Body weight was imputed for 3.3% and height for 12.5% of examinations. The mean body weight-for-age and length-for-age at birth according to gestational age was lower in EA patients and median body weight developed along the tenth percentile compared to the general population. Median height-for-age was at the 50th percentile during the first months of life, before crossing to lower percentiles before the age of one year. CHD had an additional negative impact on growth and weight gain, especially during the first year of life. Conclusions Children with EA had a reduced bodyweight and -height compared to the general population. Therefore, specific percentile curves are helpful to evaluate growth and development. Especially during the first year of life, particular attention is necessary and complications leading to a reduced calorie intake should be treated without delay to promote timely development and growth. Cardiac co-morbidities may further compromise weight gain in these patients, implying that such patients should be under even closer surveillance

Influence of medical didactic training on the self-efficacy and motivation of clinical teachers

Objectives Due to increasing workload and rising expectations for both undergraduate and speciality training in medicine, teaching in a clinical environment can be challenging. The “Train the Trainer” course, developed by CAL (Chirurgische Arbeitsgemeinschaft Lehre, Deutsche Gesellschaft für Chirurgie (DGCH)), aims to assist clinical teachers in their task. This study investigates the effect the course has on participants’ self-efficacy and teaching motivation. Methods Prior to attending the course, participants anonymously completed a 50-question pre-course questionnaire using standardised questions to gather information on biographical data teaching experience, and validated tools measuring teaching motivation and self-efficacy (PRE). Directly after completing the course, participants evaluated it using a 25-question post-course questionnaire (POST1). At least 12 months after the course, participants received a follow-up questionnaire (POST2) by mail. This 44-question form aimed to gather biographical data, review the teaching methods participants had used since their training, and reassess their teaching motivation and self-efficacy. Results Between June 2016 and October 2019, 20 TTT courses were held across six German medical faculties. Data were gathered from 241 participants. After the course, 182 POST2 questionnaires were mailed, 61 of which were returned (equals a 39 % return rate). The findings revealed significant increases in teacher self-efficacy (p=0.0025), identified regulation (p=0.0000), and career motivation (p=0.0044). In contrast, there was a significant decrease in introjected regulation (p=0.0048). When comparing the participants to a reference sample selected from literature, significant differences emerged in intrinsic motivation (p=0.0000) and amotivation (p=0.0025). Conclusions Course participants already showed strong intrinsic motivation and self-efficacy before taking the course. After completing it, their confidence to meet specific teaching demands based on their abilities had increased. Notably, changes in motivational dimensions identified and introjected regulation point towards a shift in motivational sources, indicating a more self-regulated approach towards participants’ teaching activities. Further research is needed to determine how much of this change was due to course participation

Young surgeons’ challenges at the start of their clinical residency: a semi-qualitative study

According to German regulations on licensing to practice medicine, the aim of undergraduate medical training is to produce a scientifically and practically trained physician who is able to work independently. More precisely, medical training has to impart the required knowledge and skills in diagnostics, therapy, health promotion, prevention, and rehabilitation. From the young residents’ point of view, this aim is not achieved, and they do not feel prepared to be a doctor. However, the literature on this subject relies mostly on data based on surveys, and there is a lack of deep analysis of the specific details of the topic. The aim of this study was to analyze in depth how junior doctors in their first and second years felt about their preparation for clinical practice as a doctor from their undergraduate training, as well as which teaching formats and factors influence their preparedness

Data from: What influence do courses at medical school and personal experience have on interest in practicing family medicine? – results of a student survey in Hessia

Aim: Against the background of an impending shortage of family practitioners, it is important to investigate the factors influencing the choice to become one. The aim of this study was to identify factors that encourage medical students to choose to practice family medicine. Method: Using a questionnaire, students in the fourth and fifth years of their studies in the Federal State of Hesse were asked about the factors that had influenced their choice of medical specialty and their experience of courses in family medicine. Predictors of an interest in practicing family medicine were calculated using multiple logistic regression. Results: 361 questionnaires were returned, representing a response rate of 70.9%. Confirmation of personal strengths, an interest in the field, and practical experience of the subject generally turned out to be important factors influencing the choice of medical specialty. 49.3% of students expressed an interest in practicing family medicine. A link existed between an interest in working as a family doctor and the opportunity to take over an existing practice, experience of medicine in rural areas, and an appreciation of the conditions of work. With regard to education at medical school, positive experiences during a clinical traineeship in family medicine and positive role models among teachers of general practice were identified as predictors. Conclusion: Almost half the medical students were open to the idea of practicing family medicine. Experience of medicine in rural areas and positive experiences of courses in general practice were linked to an increased interest in working as a family doctor. To promote this interest, it may be a promising approach to increase opportunities to collect experience of medicine in rural areas, and to encourage highly motivated teaching practices

Sex-specific percentiles for bodyweight and height in children born with esophageal atresia: a registry-based analysis 2001–2021

Abstract Background Esophageal atresia (EA) is a rare malformation with a wide range of co-morbidity and associated malformations impairing weight gain and growth. The aim of this study was to calculate specific percentiles for body weight and height for children born with esophageal atresia according to sex from birth to the age of 6 years, accounting for prematurity and presence of congenital heart disease (CHD). Methods Data was extracted from an anonymized voluntary national registry for patients born with esophageal atresia between 2001 and 2021, from birth until the age of six years. Missing values were imputed using a multiple imputation approach. In premature infants, chronological age was corrected for gestational week until the age of one year. The impact of sex and additional congenital heart disease on weight gain and growth was analysed using quartile regression models. Results In total, 1812 examinations of 485 patients were considered and 1232 examinations of 301 patients were finally included. Most data was available for children at birth and during the first year of life. Body weight was imputed for 3.3% and height for 12.5% of examinations. The mean body weight-for-age and length-for-age at birth according to gestational age was lower in EA patients and median body weight developed along the tenth percentile compared to the general population. Median height-for-age was at the 50th percentile during the first months of life, before crossing to lower percentiles before the age of one year. CHD had an additional negative impact on growth and weight gain, especially during the first year of life. Conclusions Children with EA had a reduced bodyweight and -height compared to the general population. Therefore, specific percentile curves are helpful to evaluate growth and development. Especially during the first year of life, particular attention is necessary and complications leading to a reduced calorie intake should be treated without delay to promote timely development and growth. Cardiac co-morbidities may further compromise weight gain in these patients, implying that such patients should be under even closer surveillance

Einfluss der Lehrmethode der Einreibetechnik zum Erlernen der hygienischen Händedesinfektion im Medizinstudium: Eine vergleichende Effektivitätsanalyse von zwei Techniken

Objective: Hygienic hand disinfection is of major importance regarding nosocomial infections and antibiotic resistance. The six-step technique is the most commonly taught method, but its superiority has not been empirically demonstrated. This study compares two hand disinfection techniques with regard to their total distribution of the disinfectant. Methods: In this comparative effectiveness analysis, medical students were randomized into two groups. Group 1 was instructed in the 6-step technique, group 2 was referred to a self-responsible application. Learning success was measured using fluorescent disinfectant and black light photographs at three time points (directly, few days later, 5–12 weeks later). Photographs were evaluated quantitatively. Results: 198 students were included in the study (Group 1: 6-step technique; n=103, Group 2: self-responsible disinfection; n=95). 186 were followed up at the second measurement, 182 at the third measurement. Directly after training, there were no significant differences between the two groups. At the second measurement, Group 2 outperformed Group 1 for total, dorsal, and palmar areas (p<0.001, p=0.002, p<0.001). At the third measurement, Group 2 was significantly better (p=0.019) for palmar-sided hands. In Group 1, areas of disinfected skin deteriorated significantly between measurement 1 and 2 (p=0.019) and measurement 2 and 3 (p<0.001). Group 2 did not deteriorate between measurement 1 and 2 (p=0.269) but between measurement 2 and 3 (p<0.001). Conclusions: Compared to the established six-step technique, a self-responsible application method results in measurably better distribution of the hand disinfectant.Problemstellung: Die hygienische Händedesinfektion ist in Zeiten von gehäuft auftretenden nosokomialen Infektionen und Antibiotikaresistenzen von größter Bedeutung. Die „6-Schritt-Methode“ ist die verbreitetste Lehrmethode, ihre Überlegenheit ist jedoch nicht evidenzbasiert. Ziel dieser Arbeit ist, die etablierte 6-Schritt-Methode mit einer eigenverantwortlichen Applikation zu vergleichen. Methode: Im Rahmen der vorliegenden vergleichenden Effektivitätsanalyse wurden Medizinstudierende in zwei Gruppen randomisiert. Gruppe 1 wurde unter Verwendung der 6-Schritt-Methode unterrichtet, während Gruppe 2 zur Desinfektion ohne Vorgabe einer speziellen Reihenfolge oder Methode unterrichtet wurde. Der Lernerfolg wurde an drei Messzeitpunkten (direkt im Anschluss an den Kurs, einige Tage später und nach 5–12 Wochen) unter Verwendung von fluoreszierendem Desinfektionsmittel und Photographien unter Schwarzlicht erhoben. Ergebnisse: Insgesamt wurden 198 Studierenden in die Studie eingeschlossen (Gruppe 1: 6-Schritt-Methode: n=103, Gruppe 2: eigenverantwortliche Desinfektion; n=95). Hiervor nahmen 186 am zweiten Messzeitpunkt und 182 am dritten Messzeitpunkt teil. Direkt nach dem Kurs konnten keine signifikanten Unterschiede zwischen den Gruppen gemessen werden. Am zweiten Messzeitpunkt zeigte Gruppe 2 eine deutlich bessere Verteilung des Desinfektionsmittels, sowohl bezogen auf die gesamte Hand als auch auf die dorsale und palmare Seite (p<0.001, p=0.002, p<0.001). Am dritten Messzeitpunkt zeigte Gruppe 2 eine signifikant bessere Desinfektion auf der palmaren Seite der Hand (p=0.019). Die Studierenden der Gruppe 1 verschlechterten sich signifikant sowohl zwischen dem ersten und zweiten Messzeitpunkt (p=0,019) als auch zwischen dem zweiten und dritten Messzeitpunkt (p<0,001). Die Studierenden der Gruppe 2 zeigten eine konstante Leistung an den ersten beiden Messzeitpunkten (p=0,269), verschlechterten sich lediglich zwischen den Messzeitpunkten zwei und drei (p<0,001). Schlussfolgerung: Die Vermittlung einer eigenverantwortlichen Methode als Lehrmethode für eine hygienische Händedesinfektion resultiert langfristig in einer messbar besseren Verteilung des Desinfektionsmittels als durch die etablierte 6-Schritt-Methode

Telementoring in Minimally Invasive Esophageal Atresia Repair: Results of a Case-Control Study and Lessons Learned from the TIC-PEA Study (Telemedical Interdisciplinary Care for Patients with Esophageal Atresia)

Minimally invasive esophageal atresia (EA) repair is deemed one of the most demanding procedures in pediatric surgery. Open repair is considered the gold standard and learning opportunities for minimally invasive repairs remain scarce. “Telemedical Interdisciplinary Care for Patients with Esophageal Atresia (TIC-PEA)” offers free access to an interdisciplinary network of experts for telemedical consultation (telementoring). The aim of this study was to determine the frequency of minimally invasive surgery (MIS) in TIC-PEA patients compared to the general population. TIC-PEA patients were matched and compared to controls regarding the use of MIS, patient characteristics, and complications. Patients (n = 31) were included at a mean age of 62.8 days (95%-CI: 41.4–84.3, 77% after the primary esophageal repair). The odds-ratio to have MIS was 4.03 (95%-confidence interval: 0.79–20.55) for esophageal anastomosis and 4.60 (95%-confidence interval: 0.87–24.22) for tracheoesophageal fistula-repair in the TIC-PEA group. Telementoring offered the chance to select the ideal candidate for MIS, plan the procedure, and review intraoperative images and videos with the expert. Telementoring as offered is ideal to promote MIS for EA and helps to address the individual learning curve. In order to maximize benefits, patients need to be included prior to the first esophageal procedure

Implementation of written structured feedback into a surgical OSCE

Background: Feedback is an essential element of learning. Despite this, students complain about receiving too little feedback in medical examinations, e.g., in an objective structured clinical examination (OSCE). This study aims to implement a written structured feedback tool for use in OSCEs and to analyse the attitudes of students and examiners towards this kind of feedback. Methods: The participants were OSCE examiners and third-year medical students. This prospective study was conducted using a multistage design. In the first step, an unstructured interrogation of the examiners formed the basis for developing a feedback tool, which was evaluated and then adopted in the next steps. Results: In total, 351 students and 51 examiners participated in this study. A baseline was created for each category of OSCE station and was supplemented with station-specific items. Each of these items was rated on a three-point scale. In addition to the preformulated answer options, each domain had space for individual comments. A total of 87.5% of the students and 91.6% of the examiners agreed or rather agreed that written feedback should continue to be used in upcoming OSCEs. Conclusion: The implementation of structured, written feedback in a curricular, summative examination is possible, and examiners and students would like the feedback to be constant

Personalized Diagnosis in Differentiated Thyroid Cancers by Molecular and Functional Imaging Biomarkers: Present and Future

Personalized diagnosis can save unnecessary thyroid surgeries, in cases of indeterminate thyroid nodules, when clinicians tend to aggressively treat all these patients. Personalized diagnosis benefits from a combination of imagery and molecular biomarkers, as well as artificial intelligence algorithms, which are used more and more in our timeline. Functional imaging diagnosis such as SPECT, PET, or fused images (SPECT/CT, PET/CT, PET/MRI), is exploited at maximum in thyroid nodules, with a long history in the past and a bright future with many suitable radiotracers that could properly contribute to diagnosing malignancy in thyroid nodules. In this way, patients will be spared surgery complications, and apparently more expensive diagnostic workouts will financially compensate each patient and also the healthcare system. In this review we will summarize essential available diagnostic tools for malignant and benignant thyroid nodules, beginning with functional imaging, molecular analysis, and combinations of these two and other future strategies, including AI or NIS targeted gene therapy for thyroid carcinoma diagnosis and treatment as well