Pemberian Tepung Bonggol Pisang pada Pakan terhadap Konsumsi Pakan dan FCR (Feed Conversion Rasio) Ayam Pedaging di Kampung Desay Distrik Prafi Kabupaten Manokwari

Pakan merupakan kebutuhan yang memakan biaya tertinggi dalam usaha peternakan. Ketersedian pakan yang terbatas dengan populasi ternak, menyebabkan Indonesia harus mengimpor pakan dari negara lain, yang dapat berdampak pada harga jual daging menjadi mahal karena faktor biaya dari pakan yang mahal. Penggunaan bahan pakan alternatif dapat menekan biaya pakan serendah dan seefisien mungkin tanpa berpengaruh buruk terhadap performan, produktifitas dan kondisi fisologi ternak. Salah satu limbah dari tanaman pisang yang masih jarang dimanfaatkan yaitu bonggolnya. Bonggol sangat berlimpah dan dapat dimanfaatkan sebagai pakan alternatif. Zat Nutrisi Bonggol Pisang dalam 100gr Kandungan nutrisi Bahan Kering, 91,56% Protein Kasar 1,72% Lemak Kasar 1,15% Serat Kasar 7,98% Karbohidrat 88,16%. Berdasarkan hasil Penelitian tentang pemanfaatan tepung bonggol pisang kapok yang ditambahkan pada pakan ternak ayam broiler dapat penulis simpulkan bahwa Penggunaan tepung bonggol pisang  kepok berpengaruh nyata pada tingkat konsumsi Feed dan Converation Ratio (FCR) terlihat dari perbedaan nilai pada setiap perlakuan berdasarkan data hasil perlakuan pada tabel konsumsi pakan dan tabel Feed Converation Rati

PENDAMPINGAN GURU DALAM MERANCANG AKTIVITAS BERMAIN KONTEN LOOSE PARTS

Abstrak: Masalah-masalah yang dihadapi guru PAUD PKG Kota Komba adalah kesulitan dalam menyediakan dan merancang media pembelajaran karena tidak memiliki kemampuan untuk membuat sendiri; kesulitan menentukan alat dan bahan untuk aktivitas anak; dan belum sepenuhnya memanfaatkan lingkungan sekitar sebagai media dan sumber belajar. Tujuan pengabdian ini adalah untuk meningkatkan kemampuan dan pemahaman guru PAUD PKG Kota Komba dalam merancang dan menerapkan aktivitas bermain menggunakan loose parts. Metode yang digunakan dalam pengabdian ini adalah workshop, mitra kegiatan ini adalah anggota PKG Kota Komba yang berjumlah 45 orang, dengan tahapan: (1) pra kegiatan, dengan menentukan waktu dan lokasi kegiatan; (2) pelaksanaan kegiatan, melalui workshop dan penugasan; serta (3) monitoring dan evaluasi menggunakan lembar observasi. Hasil kegiatan ini menunjukkan peningkatan kemampuan guru PAUD anggota PKG Kota Komba dalam merancang aktivitas bermain konten loose parts yang meningkat mencapai 88% dari 33%. Guru-guru sudah mampu memanfaatkan bahan-bahan yang tersedia di sekitar yang merupakan bahan-bahan lepasan yang dapat digunakan untuk membentuk, menyusun, menalar, meronce, memasang, mengaitkan, menempel, menganyam, dan sebagainya oleh anak sebagai media bermain yang menyenangkan serta dapat mengembangkan berbagai apek perkembangan anak.Abstract: The problems faced by teachers of PKG PAUD in Komba city are difficulty in providing and designing learning media because they do not have the ability to create their own; difficulty determining tools and materials for the child's activities; and have not fully utilized the surrounding environment as a medium and learning resource. The purpose of this devotion is to improve the ability and understanding of PAUD PKG Kota Komba teachers in designing and implementing playing activities using loose parts. The method used in this service is a workshop, this activity partner is a member of PKG Kota Komba which numbers 45 people, with stages: (1) pre-activity, by determining the time and location of the activity; (2) the implementation of activities, through workshops and assignments; and (3) monitoring and evaluation using observation sheets. The results of this activity showed an increase in the ability of PAUD teachers of PKG members of Komba City in designing loose parts content playing activities which increased by 88% from 33%. Teachers have been able to utilize the materials available around which are loose materials that can be used to form, arrange, reasoning, arranging thing together using a piece of string, install, hook, stick, weed, and so on by children as a fun playing medium and can develop a variety of child development

Mindfulness-based stress reduction in patients with interstitial lung diseases: a pilot, single-centre observational study on safety and efficacy

open11siBackground Chronic, progressive respiratory symptoms are associated with great psychological and emotional impact in patients suffering from interstitial lung disease (ILD). This single-centre pilot study evaluated for the first time the safety, feasibility and efficacy of a Mindfulness Based Stress Reduction Program (MBSR) in a group of patients with ILD. Methods Prospective observational study set in a university hospital ILD outpatient clinic. Nineteen patients with different ILDs were recruited 2 months prior to the start of the 8-week MBSR program and followed up for 12 months. Primary outcomes were program safety and feasibility, while secondary outcomes were changes in moods and stress (assessed by Profile Of Mood State (POMS) and Perceived Stress Scale (PSS) questionnaires), symptoms (Shortness Of Breath (SOB) and Cough And Sputum Assessment (CASA-Q) questionnaires), lung function and exercise tolerance at 12 months. Results Two patients (10.5%) dropped out in the observational period before the start of the MBSR intervention because of non-respiratory causes. All 17 patients who entered the 8-week MBSR program managed to complete it with an adherence average of eight sessions of nine. No adverse events related to the mindfulness training were reported. Statistically significant improvements in the POMS total score and in several individual items of POMS and PSS were observed throughout the study. However, respiratory questionnaire scores, lung function and exercise tolerance did not show a significant difference over time. Conclusions An MBSR program appears to be safe and feasible in patients with ILD, and might affect perceived moods and stress producing a positive and lasting improvement in several stress-related negative domains. These findings pave the way to larger (possibly multicentre), randomised, controlled confirmatory trials.openSgalla, Giacomo; Cerri, Stefania; Ferrari, Roberto; Ricchieri, Maria Pia; Poletti, Stefano; Ori, Margherita; Garuti, Martina; Montanari, Gloria; Luppi, Fabrizio; Petropulacos, Kyriakoula; Richeldi, LucaSgalla, Giacomo; Cerri, Stefania; Ferrari, Roberto; Ricchieri, Maria Pia; Poletti, Stefano; Ori, Margherita; Garuti, Martina; Montanari, Gloria; Luppi, Fabrizio; Petropulacos, Kyriakoula; Richeldi, Luc

Pain-related Somato Sensory Evoked Potentials: A potential new tool to improve the prognostic prediction of coma after cardiac arrest

INTRODUCTION: Early prediction of a good outcome in comatose patients after cardiac arrest still remains an unsolved problem. The main aim of the present study was to examine the accuracy of middle-latency SSEP triggered by a painful electrical stimulation on median nerves to predict a favorable outcome. METHODS: No- and low-flow times, pupillary reflex, Glasgow motor score and biochemical data were evaluated at ICU admission. The following were considered within 72 h of cardiac arrest: highest creatinine value, hyperthermia occurrence, EEG, SSEP at low- (10 mA) and high-intensity (50 mA) stimulation, and blood pressure reactivity to 50 mA. Intensive care treatments were also considered. Data were compared to survival, consciousness recovery and 6-month CPC (Cerebral Performance Category). RESULTS: Pupillary reflex and EEG were statistically significant in predicting survival; the absence of blood pressure reactivity seems to predict brain death within 7 days of cardiac arrest. Middle- and short-latency SSEP were statistically significant in predicting consciousness recovery, and middle-latency SSEP was statistically significant in predicting 6-month CPC outcome. The prognostic capability of 50 mA middle-latency-SSEP was demonstrated to occur earlier than that of EEG reactivity. CONCLUSIONS: Neurophysiological evaluation constitutes the key to early information about the neurological prognostication of postanoxic coma. In particular, the presence of 50 mA middle-latency SSEP seems to be an early and reliable predictor of good neurological outcome, and its absence constitutes a marker of poor prognosis. Moreover, the absence 50 mA blood pressure reactivity seems to identify patients evolving towards the brain death

Phantoms in medicine: the case of ophthalmology

Physical and in-silico phantoms have revealed extremely useful in the development of new surgical techniques and medical devices and for training purposes. The fabrication of eye phantoms requires knowledge of anatomy and physical principles beyond the eye physiology and medical instruments used in the clinical scenario. After a proper definition of phantoms and the discussion about their classification, the present work reviews the various phantoms developed in ophthalmology, illustrating the rationale of their design

The age-regulated zinc finger factor ZNF367 is a new modulator of neuroblast proliferation during embryonic neurogenesis.

Global population aging is one of the major social and economic challenges of contemporary society. During aging the progressive decline in physiological functions has serious consequences for all organs including brain. The age-related incidence of neurodegenerative diseases coincides with the sharp decline of the amount and functionality of adult neural stem cells. Recently, we identified a short list of brain age-regulated genes by means of next-generation sequencing. Among them znf367 codes for a transcription factor that represents a central node in gene co-regulation networks during aging, but whose function in the central nervous system (CNS), is completely unknown. As proof of concept, we analysed the role of znf367 during Xenopus laevis neurogenesis. By means of a gene loss of function approach limited to the CNS, we suggested that znf367 might act as a key controller of the neuroblast cell cycle, particularly in the progression of mitosis and spindle checkpoint. A candidate gene approach based on a weighted-gene co-expression network analysis, revealed fancd2 and ska3 as possible targets of znf367. The age-related decline of znf367 correlated well with its role during embryonic neurogenesis, opening new lines of investigation also in adult neurogenesis to improved maintenance and even repair of neuronal function

Haptic Aesthetics and Bodily Properties of Ori Gersht’s Digital Art: A Behavioral and Eye-Tracking Study.

Experimental aesthetics has shed light on the involvement of pre-motor areas in the perception of abstract art. However, the contribution of texture perception to aesthetic experience is still understudied. We hypothesized that digital screen-based art, despite its immateriality, might suggest potential sensorimotor stimulation. Original born-digital works of art were selected and manipulated by the artist himself. Five behavioral parameters: Beauty, Liking, Touch, Proximity, and Movement, were investigated under four experimental conditions: Resolution (high/low), and Magnitude (Entire image/detail). These were expected to modulate the quantity of material and textural information afforded by the image. While the Detail condition afforded less content-related information, our results show that it augmented the image’s haptic appeal. High Resolution improved the haptic and aesthetic properties of the images. Furthermore, aesthetic ratings positively correlated with sensorimotor ratings. Our results demonstrate a strict relation between the aesthetic and sensorimotor/haptic qualities of the images, empirically establishing a relationship between beholders’ bodily involvement and their aesthetic judgment of visual works of art. In addition, we found that beholders’ oculomotor behavior is selectively modulated by the perceptual manipulations being performed. The eye-tracking results indicate that the observation of the Entire, original images is the only condition in which the latency of the first fixation is shorter when participants gaze to the left side of the images. These results thus demonstrate the existence of a left-side bias during the observation of digital works of art, in particular, while participants are observing their original version

Unusual Displacement of a Mobilised Dental Bridge during Orotracheal Intubation

Dental trauma during tracheal intubation mostly happens in case of poor dentition, restricted mouth opening, and/or difficult laryngoscopy. 57-year-old man undergoing laparoscopic radiofrequency ablation of unresectable hepatocellular carcinoma had his dental work detached at induction of anesthesia. Oropharyngeal direct view, manual inspection, fibreoptic nosendoscopy, tracheobronchoscopy, and fiberoptic inspection of the esophagus and stomach were unsuccessful in locating the dislodged bridge. While other possible exams were considered, such as lateral and AP x-ray of head and neck, further meticulous manual “sweepings” of the mouth were performed, and by moving the first and second fingers below the soft palate deep towards the posterolateral wall of the pharynx, feeling consistent with a dental prosthesis was detected in the right pharyngeal recess. Only after pulling the palatopharyngeal arch upward was it possible to grasp it and extract it out with the aid of a Magill Catheter Forceps. Even though the preexisting root and bridge deficits were well reported by the consultant dentist, the patient was fully reimbursed. The lack of appropriate documentation of the advanced periodontal disease in the anesthesia records, no mention of potential risks on anesthesia consent, and insufficient protective measures during airway instrumentation reinforced the reimbursement claim

Atmospheric CO 2 concentrations and δ 13 C values between New Zealand and Antarctica, 1998 to 2010: some puzzling results

From 1998 to 2010, during eight cruises of the M/V Italica between New Zealand and Antarctica, sets of flask air samples were collected and atmospheric CO 2 concentrations were recorded. The δ 13 C of CO 2 from the 1998 to 2003 air samples have already been published and show large interannual variability and an increasing frequency of 13 C-depleted samples. These results were related to a mosaic of areas with positive air–sea fluxes. We report here δ 13 C results from air samples collected from four further cruises. δ 13 C values obtained during the 2004/2005 cruise show an inexplicable saw-toothed distribution. Air samples from the 2005/2006 cruise have δ 13 C values which match previous sets of samples (1998 to 2004) and show more frequent and more negative isotopic events. From 2006 until 2009, further samples could not be collected. However, during December 2009 and January 2010, two more sets of air samples were collected, the δ 13 C values of which greatly differ from previous results, being absolutely homogeneous and paralleled by flat CO 2 concentrations. The results of these last two sets of air samples may be due either to fortuitous environmental conditions or to an improbable and substantial change in oceanic and atmospheric conditions in this section of the circumpolar area. Keywords: New Zealand to Antarctica, flask air samples, atmospheric CO 2 concentrations, carbon isotopic composition of CO 2 , puzzling results (Published: 5 December 2012) Citation: Tellus B 2012, 64 , 17472, http://dx.doi.org/10.3402/tellusb.v64i0.1747

Converging Role for REEP1/SPG31 in Oxidative Stress

Mutations in the receptor expression-enhancing protein 1 gene (REEP1) are associated with hereditary spastic paraplegia type 31 (SPG31), a neurological disorder characterized by lengthdependent degeneration of upper motor neuron axons. Mitochondrial dysfunctions have been observed in patients harboring pathogenic variants in REEP1, suggesting a key role of bioenergetics in disease-related manifestations. Nevertheless, the regulation of mitochondrial function in SPG31 remains unclear. To elucidate the pathophysiology underlying REEP1 deficiency, we analyzed in vitro the impact of two different mutations on mitochondrial metabolism. Together with mitochondrial morphology abnormalities, loss-of-REEP1 expression highlighted a reduced ATP production with increased susceptibility to oxidative stress. Furthermore, to translate these findings from in vitro to preclinical models, we knocked down REEP1 in zebrafish. Zebrafish larvae showed a significant defect in motor axon outgrowth leading to motor impairment, mitochondrial dysfunction, and reactive oxygen species accumulation. Protective antioxidant agents such as resveratrol rescued free radical overproduction and ameliorated the SPG31 phenotype both in vitro and in vivo. Together, our findings offer new opportunities to counteract neurodegeneration in SPG31