177 research outputs found
Os processos supervisivos nas estruturas de gestão intermédia : possibilidades e limites. Um estudo de caso numa escola secundária
Dissertação de Mestrado em Supervisão Pedagógica apresentada na Escola Superior de Educação do Instituto Politécnico de Viana do CasteloEsta pesquisa centra-se nas estruturas de coordenação educativa e supervisão
pedagógica, nos departamentos curriculares. Pretende-se compreender as concepções de
supervisão e de coordenação dos coordenadores de departamento, dos professores e do próprio director, tentando-se conhecer as práticas supervisivas e coordenativas que aí ocorrem, quem é o seu mediador e em que órgão se efectivam. Constitui, também, objectivo identificação dos constrangimentos ao exercício dessas funções por parte dos seus responsáveis e das condições facilitadoras de processos de supervisão, finalizando com a apresentação de um quadro capaz de
potenciar as práticas supervisivas, numa perspectiva de projecto formativo, que se espera positivo para o desenvolvimento organizacional e profissional, com reporte ao processo educativo.
Através de uma metodologia qualitativa privilegia-se uma abordagem descritiva e
interpretativa, cujo design investigativo se enquadra no âmbito de um estudo de caso onde se podem identificar características de investigação-acção, especialmente quando os participantes, ao longo do processo, reflectem sobre a decisão e a acção e identificam as vertentes de melhoria,
assegurando-as no futuro. Enfatiza-se ainda a criação de oportunidades reflexivas através de encontros de cariz formativo que se concretizam na realização de entrevistas, assumindo-as como momentos de reflexão partilhada, que permitem conhecer o contexto educativo e propiciar o debate conjunto sobre as práticas de supervisão. O questionário, a análise documental e as notas
de campo da investigadora completam a triangulação metodológica.
Com este estudo foi possível compreender a orgânica funcional do departamento e a
forma como a escola centralizou as competências supervisivas nos grupos disciplinares e nos seus representantes. Também se pôde compreender a importância da promoção do trabalho colaborativo, no seio do grupo, cabendo ao coordenador a função de supervisionar essas práticas, o que corresponde a uma concepção de supervisão que privilegia o trabalho de pares, a hetero-supervisão.This research is centred on the structures for educational coordination and pedagogic
supervision in the various curricular departments. The purpose of the study is to better understand the concepts that department coordinators, professors and the director her/himself have regarding supervision and coordination, with particular emphasis on the supervisory and
coordinative practices that are employed, those responsible for reconciling them and the sector in which they are practiced. A further objective is the identification of the constraints to the exercise of these functions by those responsible for them and the conditions that may facilitate the
supervisory processes and, lastly, the presentation of a chart capable of increasing the potential of the supervisory practices from the standpoint of a training project that one hopes will be positive in terms of organizational and professional development, as regards the educational
process.
The use of a qualitative methodology privileges a descriptive and interpretative approach, whose investigative design fits in within the framework of a case study where one can identify action-investigation characteristics, particularly when the participants, throughout the process,
reflect on the decision and the action and identify aspects of improvement, to ensure them for the future. Emphasis is also placed on the creation of contemplative opportunities through meetings of a training nature that are concentrated on carrying out of interviews, where these are taken on as moments of shared deliberation, that enable one to better know the educational context and encourage joint deliberation of the supervisory practices. The questionnaire, the
analysis of documents and the field notes of the researcher complete the methodological
triangulation.
This study led to an understanding of the functional organics of the department and the
manner by which the school centralizes the supervisory skills on the disciplinary groups and on their representatives. One is also led to understand the importance of promoting collaborative work, within the heart of the group, it being the coordinator’s responsibility to supervise these practices, which corresponds to a supervisory concept that gives preference to paired work, that is, hetero-supervision
Avaliação do efeito de cistatinas recombinantes como possível terapia anti-inflamatória em artrite experimental
Zoonoses in humans from small rural properties in Jataizinho, Parana, Brazil.
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O site “Super Parque” : uma proposta divertida de ensino de português como segunda língua
Monografia (graduação)—Universidade de Brasília, Instituto de Letras, Departamento de Teoria Literária e Literaturas, 2013.Este trabalho é uma proposta de site para ensino de Português como segunda língua para crianças de 8 – 10 anos em contexto de imersão. A pesquisa se baseou na abordagem comunicativa da linguagem, em que teoria e atividades devem estar contextualizados. Partiu-se da análise crítica de dois sites do mercado de ensino de Português como língua materna para a produção de um site específico para Português como segunda língua. O site “Super Parque” está em construção e apresentará como foco um parque de diversões e um zoológico. A partir das imagens dos brinquedos e dos animais, as crianças, além de aprenderem palavras novas, reforçarão alguns traços gramaticais: adjetivos, gênero e número. As seções complementares “Curiosidades” e “Atividades” vêm alinhadas aos objetivos do site para enriquecer o conhecimento e tornar o aprendizado um processo ainda mais lúdico e agradável. __________________________________________________________________________ ABSTRACTThis work is a proposed site for the teaching of Portuguese as a second language for children 8-10 years of immersion context. The research was based on the communicative approach of language, in which theory and activities must be contextualized. We started from the critical analysis of two sites in the market teaching Portuguese as their mother tongue for the production of a specific site for Portuguese as a second language. The site "Super Parque" is under construction and shall focus on an amusement park and a zoo (“Parque de Diversões” and “Zoológico”, respectively). From the images of toys and animals, children, beyond learning new words, should increase their knowledge about some grammar features: adjectives, gender and number. The complementary sections "Curiosidades" and "Atividades" come in line with the objectives of the site to enrich your knowledge and make the learning process more fun and enjoyable
Specific IgG3/IgG1 isotyping may further inform diagnosis of acute disease
The laborious microscopic agglutination test (MAT) is the gold standard serologic test for laboratory diagnosis of leptospirosis. We developed EIA based serologic assays using recombinant proteins (rLigA, rLigB, rLipL32) and whole-cell extracts from eight Leptospira serovars as antigen and assessed the diagnostic performance of the new assay within each class, against MAT positive (MAT+) human sera panels from Portugal/PT (n = 143) and Angola/AO (n = 100). We found that a combination of recombinant proteins rLigA, rLigB and rLipL32 correctly identified antigen-specific IgG from patients with clinical and laboratory confirmed leptospirosis (MAT+) with 92% sensitivity and ~ 97% specificity (AUC 0.974) in serum from the provinces of Luanda (LDA) and Huambo (HBO) in Angola. A combination of whole cell extracts of L. interrogans sv Copenhageni (LiC), L. kirschneri Mozdok (LkM), L. borgpetersenii Arborea (LbA) and L. biflexa Patoc (LbP) accurately identified patients with clinical and laboratory confirmed leptospirosis (MAT+) with 100% sensitivity and ~ 98% specificity for all provinces of Angola and Portugal (AUC: 0.997 for AO/LDA/HBO, 1.000 for AO/HLA, 0.999 for PT/AZ and 1.000 for PT/LIS). Interestingly, we found that MAT+ IgG+ serum from Angola had a significantly higher presence of IgD and that IgG3/IgG1 isotypes were significantly increased in the MAT+ IgG+ serum from Portugal. Given that IgM/IgD class and IgG3/IgG1 specific isotypes are produced in the earliest course of infection, immunoglobulin G isotyping may be used to inform diagnosis of acute leptospirosis. The speed, ease of use and accuracy of EIA tests make them excellent alternatives to the laborious and expensive MAT for screening acute infection in areas where circulating serovars of pathogenic Leptospira are well defined.publishersversionepub_ahead_of_prin
Metabolic flux response to salt induced stress in the halotolerant yeast Debaryomyces hansenii
The toxic effect of NaCl and KCl, on growth of the marine yeast Debaryomyces hansenii on glucose or glycerol was studied. Above threshold value both salts inhibited specific growth rate, specific glucose and glycerol respiration rates and specific glucose fermentation rate, as well as biomass yields. The exponential inhibition constant, k, and minimum toxic concentration, cmin, were similar for all physiological parameters assayed. The effect of either salt in the specific activity of several glycolytic enzymes showed a similar inhibition pattern, although at much lower salt concentrations. In agreement with published results on glycerol phosphate dehydrogenase stimulation by salt, we present evidence in which a general glycolytic flux deviation could occur naturally during salt stress, due to the intrinsic sensitivity of the glycolytic enzymes responsible for the prosecution of glycolysis to intracellular ion concentrations.EC Contract CT 93-830 from AIR Program
Orthologous yeast genes associated with glycerol transport and metabolism
Apresentação efectuada nas "11as Jornadas de Biologia de Leveduras Professor Nicolau van Uden", realizadas na Escola Superior Agrária de Bragança, em Maio de 2003.Glycerol, besides acting as compatible solute, accumulated by S. cerevisiae to
counteract the low aw stress environments, is a key compound in the regulation of
multiple metabolic pathways. Most of the genes involved in glycerol consumption and
production are now available for this yeast. Furthermore, three genes had been
described as involved in glycerol uptake as well as export, respectively, GUP1/21 and
FPS123. Altogether, these genes regulate intracellular glycerol levels in a way not yet
completely unveiled. Some of these mechanisms, like the stimulation of glycerol
production and accumulation under stress growth conditions and the presence of
constituvely active transport for glycerol, are common to a series of other yeasts4.
Being so, we decided to search for some of the genes from glycerol uptake and
metabolism in some of those yeasts. We began using the partial genome sequencing
available for several yeasts from the Génolevures Program. Further ahead we included
Candida albicans from Stanford Genome Sequencing Data Base. Our search focused
on GUP1/2, FPS1, GPD1/2 (glycerol 3-P dehydrogenase) and GUT1 (glycerol kinase)
genes. From this search we choosed the sequences with higher similarity, which were
present in Candida tropicalis, Kluveryomyces marxianus, Kluveryomyces lactis,
Kluveryomyces thermotolerans, Pichia angusta, Pichia sorbitophila and
Zigossacharomyces rouxii, besides Candida albicans. The entire sequences of the
genes were obtained using standard procedures, like primer walking sequencing and
RACE (rapid amplification of cDNA ends). Genes were obtained by PCR and
complementation analysis was done. Sequences were used to create/enlarge gene
families, to explore the evolutionary relationship of these species and to establish the
putative relation between sequence and function
Yeast orthologues associated with glycerol transport and metabolism
Yeast Genetics and Molecular Biology Meeting, University of Washington Seattle, Washington, USA, July 27 - August 1, 2004
Dilemmas of girls and women in engineering: a study in Portugal
The reason that girls and women withdraw from science and technology
education and careers has been a universal concern in the social sciences. This
study investigated how gendered constructions of identity are translated into the
barriers and fears that female students and professional women experience in
decision-making about their careers. We conducted interviews with 63 girls and
39 women in academic and professional engineering careers, focusing on their
interpersonal relationships with boys and men in their school and occupational
engineering settings, respectively. Participant discourse highlighted the difficulties women face when managing the antagonistic discourses of femininity and
masculinity in a social environment in which they are frequently forced to
submit to hegemonic masculinity. The consequences of women’s differing discourses about the “masculine world” and the “feminine world” are discussed,
and some strategies for creating more equalitarian relational environments in
school and work settings are discussed.Fundação para a Ciência e a Tecnologia (FCT
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