Angiokeratoma Of The Vulva.

Angiokeratomas are benign tumors characterized by ectasia of blood vessels in the papillary dermis associated with acanthosis and hyperkeratosis of the epidermis. Dermatological examination of angiokeratomas of Fordyce is characterized by papular keratotic lesions of erythematous-violet color. They are more common in the scrotum, and vulvar involvement is rarely reported. Histopathology is particularly important to distinguish them from other benign and malignant tumors. The article reports the case of a middle-aged black woman with a history of chronic constipation, varicose veins of the lower limbs and cesarean section performed 20 years ago who had had multiple vulvar angiokeratomas for three months.86333-

The importance of superficial basal cell carcinoma in a retrospective study of 139 patients who underwent Mohs micrographic surgery in a Brazilian university hospital

OBJECTIVE: Mohs micrographic surgery is a specialized surgical procedure used to treat skin cancer. The purpose of this study was to better understand the profile of the patients who underwent the procedure and to determine how histology might be related to complications and the number of stages required for complete removal. METHODS: The records of patients who underwent Mohs micrographic surgery from October 2008 to November 2013 at the Dermatology Division of the Hospital of the Campinas University were assessed. The variables included were gender, age, anatomical location, histology, number of stages required and complications. RESULTS: Contingency tables were used to compare the number of stages with the histological diagnosis. The analysis showed that patients with superficial basal cell carcinoma were 9.03 times more likely to require more than one stage. A comparison between complications and histological diagnosis showed that patients with superficial basal cell carcinoma were 6.5 times more likely to experience complications. CONCLUSION: Although superficial basal cell carcinoma is typically thought to represent a less-aggressive variant of these tumors, its propensity for demonstrating “skip areas” and clinically indistinct borders make it a challenge to treat. Its particular nature may result in the higher number of surgery stages required, which may, as a consequence, result in more complications, including recurrence. Recurrence likely occurs due to the inadequate excision of the tumors despite their clear margins. Further research on this subtype of basal cell carcinoma is needed to optimize treatments and decrease morbidity

The importance of superficial basal cell carcinoma in a retrospective study of 139 patients who underwent mohs micrographic surgery in a Brazilian university hospital

OBJECTIVE: Mohs micrographic surgery is a specialized surgical procedure used to treat skin cancer. The purpose of this study was to better understand the profile of the patients who underwent the procedure and to determine how histology might be related to complications and the number of stages required for complete removal. METHODS: The records of patients who underwent Mohs micrographic surgery from October 2008 to November 2013 at the Dermatology Division of the Hospital of the Campinas University were assessed. The variables included were gender, age, anatomical location, histology, number of stages required and complications. RESULTS: Contingency tables were used to compare the number of stages with the histological diagnosis. The analysis showed that patients with superficial basal cell carcinoma were 9.03 times more likely to require more than one stage. A comparison between complications and histological diagnosis showed that patients with superficial basal cell carcinoma were 6.5 times more likely to experience complications. CONCLUSION: Although superficial basal cell carcinoma is typically thought to represent a less-aggressive variant of these tumors, its propensity for demonstrating "skip areas'' and clinically indistinct borders make it a challenge to treat. Its particular nature may result in the higher number of surgery stages required, which may, as a consequence, result in more complications, including recurrence. Recurrence likely occurs due to the inadequate excision of the tumors despite their clear margins. Further research on this subtype of basal cell carcinoma is needed to optimize treatments and decrease morbidity.Mohs micrographic surgery is a specialized surgical procedure used to treat skin cancer. The purpose of this study was to better understand the profile of the patients who underwent the procedure and to determine how histology might be related to complica7011721725sem informaçãosem informaçã

As atualizações científicas sobre a hipertensão pulmonar persistente no recém-nascido / Scientific updates on persistent pulmonary hypertension in the newborn

A hipertensão pulmonar persistente do recém-nascido ocorre quando a resistência vascular pulmonar permanece anormalmente elevada após o nascimento, resultando em desvio de sangue da direita para a esquerda através das vias circulatórias fetais. Isso, por sua vez, leva a hipoxemia grave que pode não responder ao suporte respiratório convencional.No feto, os circuitos pulmonar e sistêmico operam em paralelo, ambos os ventrículos direito e esquerdo ejetam sangue na aorta com subsequente perfusão da placenta, o órgão respiratório fetal. A hipertensão pulmonar persistente do recém-nascido ocorre quando a resistência vascular pulmonar permanece elevada após o nascimento, resultando em desvio de sangue da direita para a esquerda através das vias circulatórias fetais que leva à hipoxemia, que em alguns casos pode ser grave e não responde ao suporte respiratório convencional. A HPPN ocorre principalmente em bebês nascidos a termo ou prematuros tardios e é causada por anormalidades da vasculatura pulmonar que incluem subdesenvolvimento, desenvolvimento inadequado e má adaptação. Os  bebês com HPPN geralmente apresentam cianose e dificuldade respiratória, a HPPN está associada a fatores de risco pré-natal e uma variedade de distúrbios respiratórios primários, como síndrome de aspiração de mecônio, pneumonia, síndrome do desconforto respiratório, hérnia diafragmática congênita e hipoplasia pulmonar.

Complete regression of melanocytic nevi: clues for proper diagnosis

A histopathological study of a distinct papule isolated from a patient's neck is reported and compared to 80 melanocytic nevi. The histogenesis of this unique tumor indicates that it probably represents the residual of a melanocytic nevus in wich nevi cells have disappeared but fat infiltration and fibrosis of the dermis and the typical aspects of other cutaneous elements persisted. The finding of focal acantholytic dyskeratosis in multiple foci of the lesion may indicate melanocytic cells regression. Lesions with the histopathological appearence of melanocytic nevi, even in the absence of nevi cells, may be discovered scrutinizing the associated alterations