Changing the mind: hypnosis and diabetes

[Excerpt] Diabetes, although a physiological disorder suffers the impact of negative psychological stresses through the dysfunctional activation of the autonomic nervous and endocrine systems. In fact, a variety of psychological variables have been found to be important in the metabolic control and management of diabetic patients, particularly regarding adherence to self-care behaviors and medication. Lifestyle therapy is the cornerstone of diabetes treatment and, therefore, any intervention that is able to achieve the control of glycaemia, prevent micro and macro complications of diabetes, improve patient’s quality of life and decrease diabetes risk factors is certainly welcome. [...](undefined)info:eu-repo/semantics/publishedVersio

High risk of cardiovascular episodes and low adherence to risk factors guidelines in a population with diabetes

Although recent guidelines cover therapeutic goals, effective lipid management of patients with type 1 and type 2 diabetes to reduce cardiovascular disease (CVD) risk is still largely unattained. In the present study, we explored the electronic health records (EHR) at a specialized diabetes outpatient clinic to assess, in a real world database, the prevalence of poor lipid management in people with diabetes, the associated characteristics of this population, and the patterns of medication.Amge

Effect of particle size upon the extent of extraction of antioxidant power from the plants Agrimonia eupatoria, Salvia sp. and Satureja montana

The dependence of the extent of aqueous extraction of antioxidant compounds on particle size and contact time was studied for three important medicinal plants, that are commonly used in infusions: agrimony, sage and savoury. The effect of extraction time was dependent on the plant considered; however, ca. 5 min can be taken as the minimum period required to assure an acceptable degree of extraction of those compounds. As expected, a smaller particle size led to a higher extraction extents; a typical value of 0.2 mmis accordingly recommended. Chlorogenic acid was the dominant phenolic compound extracted from agrimony, whereas caffeic acid dominated in the case of sage or savoury. A mathematical model based on Fick’s law was developed from first principles, and its two parameters were suitably fitted to the experimental data generated – in attempts to predict the evolution of antioxidant capacity extracted during contact time, for each plant and each particle size

The effect of nanotube surface oxidation in the electrical response of MWCNT/PVDF nanocomposites

Carbon nanotubes / poly(vinylidene fluoride) composites were prepared using CNT with different oxidation and thermal treatments. The oxidation procedure leads to CNT with the most acidic characteristics that lower the degree of crystallinity of the polymer and contribute to a large increase of the dielectric constant. The surface treatments, in general, increase percolation threshold and decrease conductivity, but, on the other hand, are able to promote the nucleation of the electroactive phase of the polymer, which is suitable for the use of PVDF in sensors, actuators and other smart materials applications. Finally, the surface treatments do not seem to affect CNT interaction among them, reaching similar degrees of dispersion in all cases, as shown by the SEM results. The maximum value of the dielectric constant is ~630. It is demonstrated that the composite conductivity can be attributed to a hopping mechanism that is strongly affected by the surface treatment of the CNT.The authors thank the Fundacao para a Ciencia e a Tecnologia (FCT), Portugal, for financial support through the projects PTDC/CTM/69316/2006 and NANO/NMed-SD/0156/2007), and CIENCIA 2007 program for S.A.C.; V. S., J.S. and J.N.P. also thank FCT for the SFRH/BPD/63148/2009, SFRH/BD/60623/2009 and SFRH/BD/66930/2009 grants

Toxin profile of two Gymnodinium catenatum strains from Iberian Coastal Waters

Gymnodinium catenatum has been the main species responsible for paralytic shellfish poisoning events along the Portuguese coast (Iberian Peninsula), causing bans on bivalve harvesting that result in huge economic losses. This work presents the characterization of two novel isolates of G. catenatum regarding their growth and toxin profiles. Laboratory growth experiments revealed that, although low growth rates were obtained during cultivation, the cell yields were high compared to those reported in the literature. Evaluation of the toxin profiles, by HPLC-FLD, essentially confirmed the typical composition of toxins of this regional population (Iberian Peninsula), namely, the absence or low representation of the toxins dcNEO, GTX1,4 and NEO and a higher ratio of the toxins C1,2, GTX6 and GTX5. However, the percentage of the identified toxins varied among the strains of this study (under the same isolation, growth, and analysis conditions), and also differed from that of other strains described in the literature. Interestingly, we found a comparatively high abundance of dcSTX in both strains, relative to the other toxins, and an unquantifiable amount of C3,4 toxins. In addition to the geographic relationship between toxin profiles, chemical conversions among toxins may explain some differences encountered in the toxin profiles of G. catenatum strains.info:eu-repo/semantics/publishedVersio

New biocompatible peptide-based hydrogels as drug nanocarriers

In this work, several new hydrogelators were developed, containing a Naproxen or a Naphthalene group, and their critical aggregation concentrations were determined by fluorescence. The influence of pH on the aggregation of these molecules was also investigated.Foundation for the Science and Technology (FCT, Portugal), FEDER and QREN for financial support to the Research Centers, CFUM [PEst-C/FIS/UI0607/2013 (FCOMP-01-0124-FEDER-037291)] and CQ/UM [PEst-C/QUI/UI0686/2013 (FCOMP-01-0124-FEDER-037302)]. FCT is also acknowledged for the PhD grant of H. Vilaça (SFRH/BD/7265/2010)

CUALIDAD DE VIDA DE PROFESIONALES DE SALUD EN HOSPITAL UNIVERSITARIO

It aimed to analyze the Quality of Life (QL) of 89 nurses, 14 physical therapists and 6 nutritionists at a teaching hospital. Data collection was carried out between August and October 2005 by means of WHOQOL - bref. Data were submitted to statistic tests contemplating: sample features and QL, grouped in domains as follows: physical, psychological, social relation and environment. Among the results, it stands out: female sex (94.50%); age between 20 and 35 years old (85.32%); (80.74%) postgraduates; (44,03%) with double or triple working shifts. Total scores of the QL features, in three professional categories, presented averages over the line of neutrality or indifference with a trend to positive valueing. The physical therapists got the highest scores, while nurses got the lowest. The findings may underpin other analyses that can keep or improve the professionals’ QL.El objetivo de esta investigación fue analizar la cualidad de vida (CV) de 89 enfermeros, 14 fisioterapeutas y 06 nutricionistas de un hospital universitario. La colecta de los datos, entre agosto y octubre de 2005, se hizo por medio del WHOQOL – bref. Los datos fueron sometidos a testes estadísticos, contemplando: características de la muestra y CV, agrupadas en dominios físico, psicológico, relación social y de medio ambiente. Entre los resultados, se destacan: sexo femenino (94,50%); franja por edades entre 20 y 35 años (85,32%); 80,74% con postgrado; 44,03% con doble o triple jornada de trabajo. Los escores totales de las características de CV, en las tres categorías profesionales, presentaron medias por encima de la franja de neutralidad o indiferencia con tendencia a la valorización positiva. Los fisioterapeutas obtuvieron los mayores escores y los enfermeros, los menores. Los resultados ofrecen subsidios para otros análisis que puedan mantener y/o mejorar la CV de profesionales.O objetivo foi analisar a Qualidade de Vida (QV) de 89 enfermeiros, 14 fisioterapeutas e 06 nutricionistas de um hospital universitário. A coleta dos dados ocorreu entre agosto e outubro de 2005, por meio do WHOQOL – bref. Os dados foram submetidos a testes estatísticos contemplando: características da amostra e QV, agrupadas em domínios: físico, psicológico, relação social e de meio ambiente. Dentre os resultados destacam-se: sexo feminino (94,50%); faixa etária entre 20 e 35 anos (85,32%); 80,74% com pós-graduação; 44,03% com dupla ou tripla jornada de trabalho. Os escores totais das características de QV, nas três categorias profissionais, apresentaram médias acima da faixa de neutralidade ou indiferença com tendência à valorização positiva. Os fisioterapeutas obtiveram os maiores escores e os enfermeiros os menores. Os achados oferecem subsídios para outras análises que possam manter e/ou melhorar a QV de profissionais

Biodegradation of mono-, di- and trifluoroacetate by microbial cultures with different origins

This work focused on the biodegradation of three structurally related fluoroacetates (FAs), mono- (MFA), di- (DFA) and trifluoroacetate (TFA), using as microbial inocula samples collected from a site with a long history of industrial contamination and activated sludge obtained from a municipal wastewater treatment plant. Biodegradation experiments were carried out under different modes of substrate supplementation, which included (i) FAs fed as sole carbon sources; (ii) FAs (only for DFA and TFA) fed in co-metabolism with sodium acetate; and (iii) mixtures of MFA with DFA or TFA. Biodegradation of the target compounds was assessed through fluoride ion release. Defluorination was obtained in the cultures fed with MFA, while DFA and TFA were recalcitrant in all tested conditions. When present in mixture, DFA was shown to inhibit biodegradation of MFA, while TFA had no effect. A total of 13 bacterial isolates obtained from MFA degrading cultures were found to degrade 20mgL-1 of this compound, as single strains, when supplemented as a sole carbon source. Sequencing of the 16S rRNA gene indicated that among these degrading bacteria only Delftia acidovorans had been previously reported to be able to degrade MFA. This work shows that, despite their similar chemical structures, biodegradation of the three tested FAs is very distinct and draws attention to the unknown impacts that the accumulation of DFA and TFA may have in the environment as a result of their high recalcitrance.info:eu-repo/semantics/publishedVersio

Estudio y análisis de un nuevo dispositivo para la rehabilitación de la articulación tibiotarsal

Introduction: Currently, there are several types of devices and techniques for the rehabilitation of the tibiotarsal joint. However, complete and effective rehabilitation still falls short of expectations, since the existing devices are not adaptable to the level of torque and the number of repetitions and sessions to be performed, as these depend on each patient and on the stage at which he is finds. Objetives: To improve a mechatronic device for the rehabilitation of the tibiotarsal joint, the Therapheet. Methods: This study presents a review of the tibiotarsal joint rehabilitation protocols, as well as the classification of devices used for this purpose. Thus, the purpose is to improve the Therapheet, developed at the Department of Mechanical Engineering of the University of Minho, obtaining a viable, functional and safe rehabilitation device, standing out from the rest on the market, since it allows the execution of the six rehabilitation exercises. Results: It was obtained a prototype of equipment for rehabilitation of the tibiotarsal joint was obtained, proposing changes for improvement according to the specificities and requirements for such a device, having been subjected to a series of preliminary tests to verify its functionality, performance and suitability. The equipment proved to be functional, in terms of executing the ankle rehabilitation movements, however, it still manifests some flaws in terms of the user's stability, sudden movements, and above all dysfunctions arising from excess mass that make up its structure and limitations pneumatic technology adopted. Conclusions: The control of the amplitude of the characteristic angles of the movements of the foot is still done manually, so it would be significant to implement an automated system that would allow the control of the range of amplitude, according to the patient's rehabilitation phase. One option would be the implementation of a new technology, such as the insertion of servomotors.Introdução: Atualmente existem vários tipos de dispositivos e técnicas para a reabilitação da articulação tibiotársica. No entanto, a reabilitação completa e eficaz ainda está aquém das expectativas, uma vez que os dispositivos existentes não são adaptáveis ao nível do binário e do número de repetições e sessões a executar, pois estas dependem de cada paciente e do estádio em que este se encontra. Objetivos: Melhorar um dispositivo mecatrónico, de reabilitação da articulação tibiotársica, o Therapheet. Métodos: Neste estudo é apresentada uma revisão dos protocolos de reabilitação da articulação tibiotársica, assim como a classificação dos dispositivos utilizados para este propósito. Assim, a finalidade é aperfeiçoar o Therapheet, desenvolvido no Departamento de Engenharia Mecânica da Universidade do Minho, obtendo-se um dispositivo de reabilitação viável, funcional e seguro, destacando-se dos restantes no mercado, uma vez que permite a executação dos seis exercícios de reabilitação. Resultados: Foi obtido um protótipo de equipamento para reabilitação da articulação tibiotársica, propondo alterações de melhoria de acordo com as especificidades e os requisitos necessários para um dispositivo deste tipo, tendo sido submetido a uma série de testes preliminares para verificar a sua funcionalidade, desempenho e adequabilidade. O equipamento demonstrou ser funcional, a nível de execução dos movimentos de reabilitação do tornozelo, no entanto, ainda manifesta algumas falhas ao nível da estabilidade do utilizador, movimentos bruscos, e sobretudo disfunções provenientes de excesso de massa que compõe a sua estrutura e de limitações da tecnologia pneumática adotada. Conclusões: O controlo da amplitude dos ângulos característicos dos movimentos do pé ainda é feito manualmente, pelo que seria significativa a implementação de um sistema automatizado que possibilitasse o controlo da graduação da amplitude, de acordo com a fase de reabilitação do paciente. Uma opção seria a implementação de uma nova tecnologia, como a inserção de servomotores.Introducción: Actualmente, existen varios tipos de dispositivos y técnicas para la rehabilitación de la articulación tibiotarsal. Sin embargo, la rehabilitación completa y efectiva aún no cumple con las expectativas, ya que los dispositivos existentes no son adaptables al nivel de torque y al número de repeticiones y sesiones a realizar, ya que dependen de cada paciente y la etapa en la que se encuentra. Objetivos: Mejorar un dispositivo mecatrónico para la rehabilitación de la articulación tibiotarsal, el Therapheet. Métodos: Este estudio presenta una revisión de los protocolos de rehabilitación de la articulación tibiotarsal, así como la clasificación de los dispositivos utilizados para este propósito. Por lo tanto, el propósito es mejorar un dispositivo mecatrónico desarrollado en el Departamento de Ingeniería Mecánica de la Universidad de Minho, el Therapheet, obteniendo un dispositivo de rehabilitación viable, funcional y seguro, que se destaque del resto en el mercado, ya que permite la ejecución de los seis ejercicios de rehabilitación. Resultados: Se obtuvo un prototipo de equipo para la rehabilitación de la articulación tibiotarsal, proponiendo cambios para mejorar de acuerdo con las especificidades y requisitos de dicho dispositivo, habiendo sido sometido a un serie de pruebas preliminares para verificar su funcionalidad, rendimiento e idoneidad. El equipo demostró ser funcional, en términos de ejecución de los movimientos de rehabilitación de tobillo, sin embargo, todavía presenta algunos defectos en términos de estabilidad del usuario, movimientos bruscos y, sobre todo, disfunciones derivadas del exceso de masa que conforman su estructura y limitaciones. Tecnología neumática adoptada. Conclusións: El control de la amplitud de los ángulos característicos de los movimientos del pie todavía se realiza manualmente, por lo que sería importante implementar un sistema automatizado que permita el control del rango de amplitud, de acuerdo con la fase de rehabilitación del paciente. Una opción sería la implementación de una nueva tecnología, como la inserción de servomotores.This work has been supported by FCT – Fundação para a Ciência e Tecnologia with-in the R&D Units Project Scope: UIDP/04077/2020. It has been also supported by FCT – Fundação para a Ciência e Tecnologia within the R&D Units Project Scope: UIDB/00319/2020