On Morphological compositionality

We argue that the properties of indefinite pronouns such asthe quantifiers someone and everything, are derived by theoperations of the grammar and are interpreted compositionallyat the semantic interface. This is not what is generallyassumed in current practice, as indefinite pronouns are oftensemantically taken to be unanalyzed expressions(KARTTUNNEN, 1976; MONTAGUE, 1974; GROENENDIJK;STOKHOF, 1990). We bring further evidence that semanticcompositionality holds for wh-words in English, e.g., what andwhere, and in other languages, as proposed in Di Sciullo (2005).We attribute the fact that the interpretation of these elementsis derived compositionally to the core compositionality ofmorphological domains (DI SCIULLO, 2004). We drawconsequences of our analysis for the properties of the interfacebetween morphological structure and semantics.Neste artigo, argumentamos que as propriedades dos pronomesindefinidos como os quantificadores, someone e everything,por exemplo, são derivadas pelas operações da gramática e sãointerpretadas composicionalmente na interface semântica. Nãoé essa a visão assumida geralmente na prática corrente, já quenela os pronomes indefinidos são frequentemente tomadoscomo expressões semanticamente não decomponíveis(KARTTUNNEN, 1976; MONTAGUE, 1974; GOENENDIJK;STOKHOF, 1990). Apresentamos ainda outras evidências deque a composicionalidade semântica está presente em palavraswh do inglês, por exemplo, what e where , e de outras línguas,como proposto em Di Sciullo (2005). Atribuímos o fato de quea interpretação desses elementos seja derivadacomposicionalmente à centralidade da composicionalidade nosdomínios morfológicos (DI SCIULLO, 2004). Mostramos asconsequências de nossa análise para as propriedades dainterface entre estrutura morfológica e semântica

Maria del Pilar Martin to Mr. James Meredith (1 October 1962)

https://egrove.olemiss.edu/mercorr_pro/1392/thumbnail.jp

Reference to the index of the Meredith Family Papers

Index to the papers of George and Mary Ann Meredith and family and of John and Maria (Hammond) Meredith and family of Cambria, Swansea Tasmania. The Meredith family arrived in March 1821 and, having heard there was good land at Oyster Bay, a small party set out in a boat to explore the district of Oyster Bay. They found the land not as good as reported but made selections which were granted. George was granted 2000 acres on a rivulet of the Swan River and another 1000 acres at Jericho. With a large family to support, and more expected, Meredith developed many business interests and spent much of his time travelling between Swansea, Jericho and Hobart, leaving his family to tend the property. He also took an interest in public affairs and was connected with a newspaper for settlers The Colonist : Private Deposit G

Characterization of a second open reading frame in genome segment 10 of bluetongue virus

Viruses have often evolved overlapping reading frames in order to maximise their coding capacity. Until recently, the segmented double-stranded (ds) RNA genome of viruses of the Orbivirus genus was thought to be monocistronic but the identification of the bluetongue virus (BTV) NS4 protein changed this assumption. A small open reading frame (ORF) in segment 10, overlapping the NS3 ORF in the +1 position that is maintained in more than 300 strains of the 26 different BTV serotypes and in more of 200 strains of the phylogenetically related African horse sickness (AHSV). In BTV, this ORF (named S10-ORF2 in this study) encodes a putative protein of 50-59 amino acid residues in length and appears to be under a strong positive selection. HA- or GFP-tagged versions of S10-ORF2 expressed from transfected plasmids localised within the nucleoli of transfected cells unless a putative nucleolar localisation signal was mutated S10-ORF2 inhibited gene expression, but not RNA translation, in transient transfection reporter assays. In both mammalian and insect cells, BTV S10-ORF2 deletion mutants (BTV8ΔS10-ORF2) displayed similar replication kinetics to wild type virus. In vivo, S10-ORF2 deletion mutants were pathogenic in mouse models of disease. Although further evidence is required for S10-ORF2 expression during infection, the data presented provide an initial characterisation of this open reading frame

Examination of the Impact of Various Training Approaches on Different UAS Operator Populations

In recent years, the UAS industry has extended beyond military and recreational use and is now positioned to become a major portion of the aviation industry. As we move toward UAS integration into the national airspace system, UAS operators need effective training to ensure safe operation. Training UAS operators in an engaging way is important to ensure the best performance and transfer of training. Training methods that elicit high levels of learner engagement have been shown to improve knowledge gains, performance, and therefore such training techniques provide an opportunity for improving UAS training effectiveness and transfer. The growth of the UAS industry across various domains such as first responders and industrial inspectors has resulted in a broad demographic of end users. Given this, training may need to be tailored based on the population to ensure an engaging experience. To examine this topic, a study was conducted in which UAS pilots from the student population and first responder population participated in UAS training to test the effect of different training approaches on learner engagement of different end user populations. Participants engaged in instructional videos, simulation challenges, and live obstacle courses and were measured on their engagement levels and performance. This presentation will describe the methods and findings associated with the study along with implications for the aviation industry

Adolescents and Young Adults with Chronic or End-Stage Kidney Disease

Adolescents and young adults face unique and complex physical, psychological, and family challenges. Despite improvements in care for chronic kidney disease (CKD) and end-stage kidney disease (ESKD), long-term mortality for children, adolescents, and young adults with CKD remains substantially higher than their healthy counterparts. In this article, we discuss the complex challenges that adolescent and young adult CKD/ESKD patients face. Adolescents have different CKD etiologies and progress along a course dissimilar to the adult population, but have similar multifarious comorbidities. In the setting of puberty and learning to become self-sufficient, adolescence is a critical time for growth and psychosocial development. Physiological complications of CKD underlie many of the long-term outcomes. CKD-mineral and bone disorder and anemia are particularly challenging given that they are exacerbated by the rapid growth of adolescents. Endocrine imbalances and malnutrition can delay and limit growth. All of these factors, together with family dynamics and socioeconomic status, contribute to the poor long-term outcomes and decreased quality of life (QoL) for these patients and their families. Care for the adolescent CKD/ESKD population is uniquely challenging, but research has identified ways in which we can continue to improve long-term outcomes and QoL for adolescents with CKD/ESKD

Advanced Air Mobility Human factors Considerations for Current eVTOL Pilot Interfaces

Advanced air mobility (AAM) is a novel transportation concept using electric vertical take-off and landing (eVTOL) aircraft to move people and cargo in urban and rural environments. The emergence of AAM has led to a range of different eVTOL vehicle designs at different stages in development, flight testing, and certification. Although these aircraft will serve similar markets, they will have different operational capabilities and pilot interfaces. These aircraft vary in whether they are (a) multi-rotor and have tilt-rotor capabilities, or (b) winged with tilt-wing capabilities, vectored thrust, fans, or propellers. The pilot interfaces in eVTOL align with the concept of simplified vehicle operations (SVO), which emphasizes the use of automation to simplify the physical control a pilot has on the aircraft, effectively reducing workload. Pilot interfaces range in their level of landing precision information, the number of displays, checklist presentation, and how battery information is presented. A preliminary survey was conducted to determine common trends in eVTOL pilot interfaces. Common trends identified include large displays, integration of flight information such as speed, altitude, heading, climb and descent rate, flight path, battery power information, origin and destination of the flight, weather information, aircraft range and location, tilt information, and rotation per minute (RPM). This presentation will investigate trends in the eVTOL pilot interfaces and the associated human factors issues that may arise due to these interfaces. Additionally, simulation testbeds available to examine the human factors issues associated with these pilot interfaces will be presented

City Heights Community Development Corporation Performance Audit

The City Heights Community Development Corporation (CHCDC) is a 30-year-old nonprofit organization that strives “to enhance the quality of life in City Heights by working with the community to create quality affordable housing, livable neighborhoods, foster economic self- sufficiency, and stimulate investment” (City Heights Community Development Corporation, 2009). The CHCDC is an instrumental organization and an asset to the diverse community of City Heights. The leadership team is enhancing awareness, working through adaptive challenges, building relationships with potential funders and partners, and establishing a healthy organizational culture. Most importantly, the organization is taking the right steps to ensure it stays true to its mission by meeting the needs of the City Height’s community. The consulting team performed a comprehensive audit to ensure the company was in compliance with best organizational practices.https://digital.sandiego.edu/npi-bpl-programdesign/1001/thumbnail.jp

Modern Day Slavery in Our Own Backyard

Trafficking in persons is one of the fastest growing areas of international criminal activity. Each year an estimated 600,000 – 800,000 human beings are bought, sold or forced across the world’s borders. Approximately 2.5 million men, women and children are victims of trafficking at any point in time throughout the world. Approximately 14,500 – 17,500 individuals are trafficked annually into the United States, making the United States the third largest destination country in the world for victims of human trafficking. In order to fight trafficking in the United States effectively, legislation at the state level, in addition to the federal anti-trafficking laws, is critical. Although many states have laws addressing kidnapping and prostitution and many state constitutions and laws address the issue of slavery, it is important that each state have legislation specifically addressing human trafficking. Thirteen states have already enacted anti-trafficking legislation and thirteen states have pending legislation. Thus, more than half of the states have taken action or are taking action in this area since the State of Washington became the first state to enact legislation in 2003. Many more states have acknowledged the need for legislation at the state level. Once the legislation is in place, the focus must be on education and training of law enforcement, non-governmental agencies, and the public, and on the facilitation of collaboration across agencies

EphA4 expression promotes network activity and spine maturation in cortical neuronal cultures

<p>Abstract</p> <p>Background</p> <p>Neurons form specific connections with targets via synapses and patterns of synaptic connectivity dictate neural function. During development, intrinsic neuronal specification and environmental factors guide both initial formation of synapses and strength of resulting connections. Once synapses form, non-evoked, spontaneous activity serves to modulate connections, strengthening some and eliminating others. Molecules that mediate intercellular communication are particularly important in synaptic refinement. Here, we characterize the influences of EphA4, a transmembrane signaling molecule, on neural connectivity.</p> <p>Results</p> <p>Using multi-electrode array analysis on <it>in vitro </it>cultures, we confirmed that cortical neurons mature and generate spontaneous circuit activity as cells differentiate, with activity growing both stronger and more patterned over time. When EphA4 was over-expressed in a subset of neurons in these cultures, network activity was enhanced: bursts were longer and were composed of more spikes than in control-transfected cultures. To characterize the cellular basis of this effect, dendritic spines, the major excitatory input site on neurons, were examined on transfected neurons <it>in vitro</it>. Strikingly, while spine number and density were similar between conditions, cortical neurons with elevated levels of EphA4 had significantly more mature spines, fewer immature spines, and elevated colocalization with a mature synaptic marker.</p> <p>Conclusions</p> <p>These results demonstrate that experimental elevation of EphA4 promotes network activity <it>in vitro</it>, supporting spine maturation, producing more functional synaptic pairings, and promoting more active circuitry.</p