22,522 research outputs found
Enabling conditions for professional development of te reo MÄori teachers
The paper outlines a professional development programme for secondary school teachers of te reo MÄori (under the auspices of Te Hiringa i te Mahara) conducted by a language teacher educator and an expert in MÄori bilingualism and biliteracy. While the principles underpinning the programme reflect a strong task-based
orientation, the programme approached development needs for the teachers from the point of view of understanding âenabling conditionsâ (Franken, Rau, Ngata & Parata, n.d.) for effective language learning and teaching (see also Ellis, 2005),
rather than understanding task based learning and teaching per se. The programme drew on the current practices of the teachers and made use of epistemology of MÄori language and MÄori language learning. The paper presents observations from monitoring data collected during the programme supporting the claim that such an approach to the professional development of language teachers promotes a strong knowledge base and pedagogical reasoning skills (Richards, 1998), and in particular for te reo MÄori teachers, fosters a sense of their own professional identity
Metformin reverses development of pulmonary hypertension via aromatase inhibition
Females are more susceptible to pulmonary arterial hypertension than males, although the reasons remain unclear. The hypoglycemic drug, metformin, is reported to have multiple actions, including the inhibition of aromatase and stimulation of AMP-activated protein kinase. Inhibition of aromatase using anastrazole is protective in experimental pulmonary hypertension but whether metformin attenuates pulmonary hypertension through this mechanism remains unknown. We investigated whether metformin affected aromatase activity and if it could reduce the development of pulmonary hypertension in the sugen 5416/hypoxic rat model. We also investigated its influence on proliferation in human pulmonary arterial smooth muscle cells. Metformin reversed right ventricular systolic pressure, right ventricular hypertrophy, and decreased pulmonary vascular remodeling in the rat. Furthermore, metformin increased rat lung AMP-activated protein kinase signaling, decreased lung and circulating estrogen levels, levels of aromatase, the estrogen metabolizing enzyme; cytochrome P450 1B1 and its transcription factor; the aryl hydrocarbon receptor. In human pulmonary arterial smooth muscle cells, metformin decreased proliferation and decreased estrogen synthesis by decreasing aromatase activity through the PII promoter site of Cyp19a1. Thus, we report for the first time that metformin can reverse pulmonary hypertension through inhibition of aromatase and estrogen synthesis in a manner likely to be mediated by AMP-activated protein kinase
The Harold C. Ernst Collection of Portable Sundials
A catalog of sundials from the Harold C. Ernst Collection of Portable Sundials, and a handy reference book on the subject of portable sundials.
The sundial is the most ancient scientific instrument to come down to us unchanged. As such it is deserving of a better position in life than that of an ornament. It has played a vital part in the life of man for many thousands of years, and even today it serves us well where the mechanical watch fails. The authors particularly draw attention to the system of classifying, labeling, and cataloging sundials, described in Chapter II. This is the first attempt to bring order out of confusion in sundials
Narrative Quilts and Quilted Narratives: The Art of Faith Ringgold and Alice Walker
There have been two main streams of influence on Chicano artists aside from the obvious one that is the result of their artistic training, education and development in the United States. The primary influence came from Mexico, first during the colonial period in the form of New Spanish art and architecture, and then in modem times provided by the Mexican muralists through their work and their use of pre-Columbian art. The New Spanish materials formed the nucleus for the second stream of influence composed of the various manifestations of religious folk art found primarily in the Southwest
Initial investigation of the wavelength dependence of optical properties measured with a new multi-pass Aerosol Extinction Differential Optical Absorption Spectrometer (AE-DOAS)
Atmospheric aerosols directly affect climate by scattering and absorbing radiation. The magnitude of the impact is dependent upon the wavelength of light, but is often estimated near 550 nm. When light scattering and absorption by aerosols is approximated, the wavelength dependence of the refractive index for speciïŹc components is lost. As a result, climate models would have inherent uncertainties for aerosol contributions to radiative forcing when considering the entire solar spectrum. An aerosol extinction differential optical absorption spectrometer has been developed to directly measure aerosol extinction at mid-ultraviolet to near infrared wavelengths. The instrument consists of a spectrometer coupled to a closed White-type multi-pass gas cell with an adjustable path length of up to approximately 20 m. Laboratory measurements of various gases are compared with known absorption cross sections. Additionally, the extinction of monodisperse samples of polystyrene latex spheres are measured and compared to Mie theory generated with refractive index values from the literature to validate the new instrument. The polystyrene experiments also emphasize the ability of the new instrument to retrieve the wavelength dependent refractive index, especially in the ultraviolet wavelength regions where variability is expected. The spectrometer will be a signiïŹcant advancement for determining wavelength dependent complex refractive indices in future laboratory studies as well as provide the ability to monitor ambient aerosol light extinction
Reducing Causal Ambiguity in Acquisition Integration: Intermediate Goals as Mediators of Integration Decisions and Acquisition Performance
Integration is a difficult process, but one that is vital to acquisition performance. One reason acquirers encounter difficulties is that the integration process exhibits high levels of intrafirm linkage ambiguity â a lack of clarity of the causal link between integration decisions and their performance outcomes. We introduce the construct of intermediate goals as a mechanism that reduces intrafirm linkage ambiguity. Our structural model results, based on a sample of 129 horizontal acquisitions, indicate that the achievement of two intermediate goals (internal reorganization and market expansion) fully mediates the relationships between four integration decisions and acquisition performance
Factors Associated with Colorectal Cancer Screening among Younger African American Men: A Systematic Review
Of cancers affecting both men and women, colorectal cancer (CRC) is the second leading cancer killer among African Americans in the U.S. Compared to White men, African American men have incidence and mortality rates 25% and 50% higher from CRC. Despite the benefits of early detection and the availability of effective screening, most adults over age 50 have not undergone testing, and disparities in colorectal cancer screening (CRCS) persist. Owing to CRCâs high incidence and younger age at presentation among African American men, CRCS is warranted at age 45 rather than 50. However, the factors influencing young adult (i.e., age \u3c 50) African American menâs intention to screen and/or their CRCS behaviors has not been systematically assessed. To assess whether the factors influencing young adult African American menâs screening intentions and behaviors are changeable through structured health education interventions, we conducted a systematic review, with the two-fold purpose of: (1) synthesizing studies examining African American men\u27s knowledge, beliefs, and behaviors regarding CRCS; and (2) assessing these studiesâ methodological quality. Utilizing Garrardâs Matrix Method, a total of 28 manuscripts met our inclusion/exclusion criteria: 20 studies followed a non-experimental research design, 4 comprised a quasi-experimental design, and 4, an experimental design. Studies were published between 2002 and 2012; the majority, between 2007 and 2011. The factors most frequently assessed were behaviors (79%), beliefs (68%), and knowledge (61%) of CRC and CRCS. Six factors associated with CRC and CRCS emerged: previous CRCS, CRC test preference, perceived benefits, perceived barriers, CRC/CRCS knowledge, and physician support/recommendation. Studies were assigned a methodological quality score (MQS â ranging from 0 to 21). The mean MQS of 10.9 indicated these studies were, overall, of medium quality and suffered from specific flaws. Alongside a call for more rigorous research, this review provides important suggestions for practice and culturally relevant interventions
A tool for estimating Best Management Practice effectiveness in Arkansas
Increased nutrient and sediment losses from expanding agricultural practices and urban development in Arkansas are important environmental concerns. Best Management Practices (BMPs) are being implemented to lessen the effects of these developments on existing water bodies. There is, however, insufficient scientific base as to the effectiveness of these practices. A number of studies have been conducted in recent years to determine BMP effectiveness. Data from these studies can only be reliably used for the individual site from which they were obtained. When considered collectively, these data comprise quantitative effectiveness over a wide range of conditions and can thus be used to provide reliable estimates of BMP effectiveness. This study develops a tool for estimating BMP effectiveness, based on accumulation and analyses of data reported in previous studies, with a focus on site conditions and management interventions in Arkansas. This study incorporates data from a variety of regions in the southeastern U.S., which have site conditions and management similar to those in Arkansas. Developed within MicrosoftŸ Access© from a pre-existing BMP characterization tool, this tool will be made accessible to local and state agencies and will aid rural and urban planners in developing management solutions for nutrients and sediment control. The tool describes individual BMPs in detail and gives site-specific estimates of their long-term effectiveness in sediment and nutrient control
Manos Teatrales: Cyber-Paleography and a Virtual World of Spanish Golden Age Theater
In the Manos Teatrales (Theatrical Hands) project, literary scholars, historians and computer scientists will develop manual and automatic methods for analyzing rich manuscripts collections and their societies, using the treasure-trove of Spanish Golden Age theater and related archival records as a case study. Our cyber-paleography effort will build a live, layered virtual world on the web, open to librarians, scholars and students. A first layer will connect digitally restored images of manuscript pages to descriptions of the pen strokes on paper. Manual and automatic analysis of these descriptions will yield profiles of the writers' handwriting styles and enable semi-automatic inferences based on machine learning methods, about who wrote what and when. A second layer will connect sources to individual and collective histories of the theater community and help scholars understand it. A third layer will describe the techniques of cyber-paleography for both humanists and scientists
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