Evaluation of coastal and marine ecosystem services of Mayotte:indirect use values of coral reefs and associated ecosystems

Coral reefs of Mayotte (342 km2), seagrass beds (7.6 km2) and mangroves (8.5 km2) provide important ecosystem services of which the most important are the coastal protection, fish biomass production, carbon sequestration and water purification. The quantity and quality of these services have been decreasing steadily for several years and should continue to do so if no action is taken to contain anthropogenic pressures. The coral cover of the fringing reefs and the barrier reef has thus declined, respectively, by 60% in 15 years and 15% in 8 years. The pioneer front of Sonneratia for mangroves has declined by 13% in 6 years, and for seagrass beds, the water quality suggests a degraded state. The estimated annual value of these services amounts to EUR 124 million. It would be EUR 162 million if the ecosystems were in pristine conditions. The article shows that the preservation of coastal ecosystems is essential from an economic point of view.EDITED BY Sebastian Villasant

TRIDENT: an Infrared Differential Imaging Camera Optimized for the Detection of Methanated Substellar Companions

A near-infrared camera in use at the Canada-France-Hawaii Telescope (CFHT) and at the 1.6-m telescope of the Observatoire du Mont-Megantic is described. The camera is based on a Hawaii-1 1024x1024 HgCdTe array detector. Its main feature is to acquire three simultaneous images at three wavelengths across the methane absorption bandhead at 1.6 microns, enabling, in theory, an accurate subtraction of the stellar point spread function (PSF) and the detection of faint close methanated companions. The instrument has no coronagraph and features fast data acquisition, yielding high observing efficiency on bright stars. The performance of the instrument is described, and it is illustrated by laboratory tests and CFHT observations of the nearby stars GL526, Ups And and Chi And. TRIDENT can detect (6 sigma) a methanated companion with delta H = 9.5 at 0.5" separation from the star in one hour of observing time. Non-common path aberrations and amplitude modulation differences between the three optical paths are likely to be the limiting factors preventing further PSF attenuation. Instrument rotation and reference star subtraction improve the detection limit by a factor of 2 and 4 respectively. A PSF noise attenuation model is presented to estimate the non-common path wavefront difference effect on PSF subtraction performance.Comment: 41 pages, 16 figures, accepted for publication in PAS

Assessment of indirect use values ​​of coral reefs and associated ecosystems in Mayotte

Les récifs coralliens de Mayotte (342 km2), ainsi que ses mangroves (8,46 km2) et ses herbiers (7,60 km2) procurent des services écosystémiques dont les plus importants sont la protection côtière, la séquestration de carbone, le traitement des eaux et la production de biomasse halieutique. La quantité et la qualité de ces services diminuent de manière régulière depuis plusieurs années et elles devraient continuer de la sorte si aucune mesure n’est prise pour contenir les pressions anthropiques. La couverture corallienne des récifs frangeants a ainsi diminué de 60 % en 15 ans et celle du récif barrière de 15 % en 8 ans, alors que les fronts pionniers de Sonneratia des mangroves ont régressé de 13 % en 6 ans. La qualité écologique des masses d’eaux suggère quant à elle un état dégradé des herbiers. La valeur monétaire annuelle de l’ensemble de ces services est actuellement estimée à 151 millions d’euros. Si les écosystèmes étaient en parfait état écologique, elle s’élèverait alors à 188 millions d’euros. Cet article montre ainsi que la préservation des écosystèmes côtiers est primordiale d’un point de vue économique.Mayotte’s coral reefs (342 km2), mangroves (8, 46 km2) and seagrass beds (7,60 km2) provide important ecosystem services of which the most important are the coastal protection, carbon sequestration, water purification and fish biomass production. The quantity and quality of these services have been decreasing steadily for several years and should continue to do so if no action is taken to contain anthropogenic pressures. The coral cover of the fringing reefs and the barrier reef has thus declined respectively by 60 % in 15 years and 15 % in 8 years, while the pioneer front of Sonneratia for mangroves has declined by 13 % in 6 years. As for the water quality, it suggests a degraded state of seagrass beds. The estimated annual value of these services amounts to EUR 151 million. This value would then rise to EUR 188 million if the ecosystems were in pristine conditions. This article shows that the preservation of coastal ecosystems is essential from an economic point of view

Coastal protection assessment: a tradeoff between ecological, social, and economic issues

Marine coastal ecosystems are crucial to human populations in reducing disaster risk. Least Developed Countries are particularly vulnerable to the effects of climate change, such as sea-level rise and storm surges. The Mauritanian coast, West Africa, ranks among the most vulnerable worldwide to sea-level rise, and coastal communities in the National Park of Banc d’Arguin (PNBA) are particularly at risk. Here, we assessed the service of coastal protection in PNBA by (1) mapping the coastal marine ecosystems with Sentinel-2 imagery and determining their spatial wave height attenuation rates; (2) assessing the vulnerability of villages and natural habitats to coastal hazard risk; and (3) assessing the applicability of coastal protection measures in the PNBA. We found that a total of 83% of the populated coastline presents a moderate to high risk of flooding and erosion, with Iwik and R’Gueiba being the most threatened villages in the PNBA. As for the ecological risk, two low-elevated islands, which support breeding colonies of birds, are particularly vulnerable to sea-level rise. However, in other areas, the rupture in the dune cord created new lagoons that present valuable ecological and economic interests like the Lagoon of Bellaat. Improving the comprehension of wave attenuation provided by coastal habitats, combined with identifying the vulnerability and applicability of coastal protection measures, is essential for achieving the Sendai Framework for Disaster Risk Reduction goals. In the PNBA, relocation of identified villages at risk is probably the best cost-effective solution with the least disturbance to both breeding and wintering birds. Protection of coastal ecosystems will also ensure a continued provision of other ecosystem services, including food supply for sea dependent populations, and contribute to achieving the Paris Agreement and Sustainable Development Goals

Mitochondrial Dysfunction as an Arrhythmogenic Substrate A Translational Proof-of-Concept Study in Patients With Metabolic Syndrome in Whom Post-Operative Atrial Fibrillation Develops

ObjectivesThis study sought to provide bedside evidence of the potential link between cardiac mitochondrial dysfunction and arrhythmia as reported in bench studies.BackgroundAtrial fibrillation (AF) is a frequent complication of cardiac surgery. Underlying mechanisms of post-operative atrial fibrillation (POAF) remain largely unknown. Because cardiac mitochondrial dysfunction has been reported in clinical conditions with a high risk of POAF, we investigated whether a causal link exists between POAF onset and pre-operative function of cardiac mitochondria.MethodsPre-operative mitochondrial respiration and calcium retention capacity, respiratory complex activity, and myocardial oxidative stress were quantified in right atrial tissue from 104 consecutive patients with metabolic syndrome, in sinus rhythm, and undergoing coronary artery bypass graft surgery.ResultsIn this high-risk population, POAF occurred in 44% of patients. Decreased pre-operative mitochondrial respiration and increased sensitivity to calcium-induced mitochondrial permeability transition pore opening were significantly associated with POAF. Adenosine diphosphate–stimulated mitochondrial respiration supported by palmitoyl-l-carnitine was significantly lower in POAF patients and remained independently associated with AF onset after adjustment for age, body mass index, heart rate, beta-blocker use, and statin medication (multivariate logistic regression coefficient per unit = −0.314 ± 0.144; p = 0.028). Gene expression profile analysis identified a general downregulation of the mitochondria/oxidative phosphorylation gene cluster in pre-operative atrial tissue of patients in whom AF developed.ConclusionsOur prospective study identifies an association between pre-operative mitochondrial dysfunction of the atrial myocardium and AF occurrence after cardiac surgery in patients with metabolic disease, providing novel insights into the link between mitochondria and arrhythmias in patients

Addressing Soil Degradation in EU Agriculture: Relevant Processes, Practices and Policies - Report on the project 'Sustainable Agriculture and Soil Conservation (SoCo)'

Agriculture occupies a substantial proportion of the European land, and consequently plays an important role in maintaining natural resources and cultural landscapes, a precondition for other human activities in rural areas. Unsustainable farming practices and land use, including mismanaged intensification as well as land abandonment, have an adverse impact on natural resources. Having recognised the environmental challenges of agricultural land use, the European Parliament requested the European Commission in 2007 to carry out a pilot project on "Sustainable Agriculture and Soil Conservation through simplified cultivation techniques" (SoCo). The project originated from a close cooperation between the Directorate-General for Agriculture and Rural Development (DG AGRI) and the Joint Research Centre (JRC). It was implemented by the Institute for Prospective Technological Studies (IPTS) and the Institute for Environment and Sustainability (IES). This report presents the findings of a stock-taking of the current situation with respect to soil degradation processes, soil-friendly farming practices and relevant policy measures within an EU-wide perspective. This overview includes the results of the survey on the national/regional implementation of EU policies and national policies, a classification of the described soil degradation processes, soil conservation practices and policy measures, and finally the outcome of the Stakeholder Workshop which took place on 22 May 2008 in Brussels.JRC.J.5-Agriculture and Life Sciences in the Econom

HIV-1 assembly in macrophages

The molecular mechanisms involved in the assembly of newly synthesized Human Immunodeficiency Virus (HIV) particles are poorly understood. Most of the work on HIV-1 assembly has been performed in T cells in which viral particle budding and assembly take place at the plasma membrane. In contrast, few studies have been performed on macrophages, the other major target of HIV-1. Infected macrophages represent a viral reservoir and probably play a key role in HIV-1 physiopathology. Indeed macrophages retain infectious particles for long periods of time, keeping them protected from anti-viral immune response or drug treatments. Here, we present an overview of what is known about HIV-1 assembly in macrophages as compared to T lymphocytes or cell lines

Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

Aims The objective of the Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) was to determine whether aliskiren, a direct renin inhibitor, would improve post-discharge outcomes in patients with hospitalization for heart failure (HHF) with reduced ejection fraction. Pre-specified subgroup analyses suggested potential heterogeneity in post-discharge outcomes with aliskiren in patients with and without baseline diabetes mellitus (DM). Methods and results ASTRONAUT included 953 patients without DM (aliskiren 489; placebo 464) and 662 patients with DM (aliskiren 319; placebo 343) (as reported by study investigators). Study endpoints included the first occurrence of cardiovascular death or HHF within 6 and 12 months, all-cause death within 6 and 12 months, and change from baseline in N-terminal pro-B-type natriuretic peptide (NT-proBNP) at 1, 6, and 12 months. Data regarding risk of hyperkalaemia, renal impairment, and hypotension, and changes in additional serum biomarkers were collected. The effect of aliskiren on cardiovascular death or HHF within 6 months (primary endpoint) did not significantly differ by baseline DM status (P = 0.08 for interaction), but reached statistical significance at 12 months (non-DM: HR: 0.80, 95% CI: 0.64-0.99; DM: HR: 1.16, 95% CI: 0.91-1.47; P = 0.03 for interaction). Risk of 12-month all-cause death with aliskiren significantly differed by the presence of baseline DM (non-DM: HR: 0.69, 95% CI: 0.50-0.94; DM: HR: 1.64, 95% CI: 1.15-2.33; P < 0.01 for interaction). Among non-diabetics, aliskiren significantly reduced NT-proBNP through 6 months and plasma troponin I and aldosterone through 12 months, as compared to placebo. Among diabetic patients, aliskiren reduced plasma troponin I and aldosterone relative to placebo through 1 month only. There was a trend towards differing risk of post-baseline potassium ≥6 mmol/L with aliskiren by underlying DM status (non-DM: HR: 1.17, 95% CI: 0.71-1.93; DM: HR: 2.39, 95% CI: 1.30-4.42; P = 0.07 for interaction). Conclusion This pre-specified subgroup analysis from the ASTRONAUT trial generates the hypothesis that the addition of aliskiren to standard HHF therapy in non-diabetic patients is generally well-tolerated and improves post-discharge outcomes and biomarker profiles. In contrast, diabetic patients receiving aliskiren appear to have worse post-discharge outcomes. Future prospective investigations are needed to confirm potential benefits of renin inhibition in a large cohort of HHF patients without D