Flexibilidad y creatividad emprendedora en pos de la creación de negocios de impacto

La actividad emprendedora puede tener una especial importancia en lo que respecta a la atención de problemáticas sociales y medioambientales, más allá de la generación de beneficios económicos para quienes decidan realizarla. Gracias a la flexibilidad y creatividad que generalmente caracteriza a los emprendedores, los proyectos empresariales por ellos generados pueden conseguir altos niveles de adaptación a necesidades de impacto en periodos de tiempo relativamente cortos. La capacidad y velocidad de actuar por el impacto está mayormente restringida para las grandes empresas, por causas de diferente índole. Ello no significa que sea un objetivo imposible de conseguir, sino que tal vez insuma más tiempo y deba ser llevado a cabo con menor libertad de acción que muchos modelos de negocio emprendedor. La educación superior tiene el potencial de formar, motivar y acompañar a los emprendedores que quieran atravesar el camino hacia la consecución del impacto, brindándoles las herramientas y el apoyo necesarios para intentar crear soluciones disruptivas a problemas comunes.Entrepreneurial activity can have a special importance regarding the attention of social and environmental problems, beyond the generation of economic benefits for those who decide to carry it out. Thanks to the flexibility and creativity that normally characterizes entrepreneurs, the business initiatives generated by them can achieve high levels of adaptation to impact needs in relatively short periods of time. The capacity and speed of action for the impact is mostly restricted for large companies, for different reasons. This doesn´t mean that it is an impossible achievement, but that it may take longer and should be carried out with a higher level of constraints than many entrepreneurial business models. College education has the potential to educate, motivate and mentor entrepreneurs who are willing to work for impact achievement, providing the needed tools and support for them to create disruptive solutions to common problems.A atividade empreendedora pode ter especial importância no atendimento de problemas sociais e ambientais, além da geração de benefícios econômicos para quem decide realizá-la. Graças à flexibilidade e criatividade que geralmente caracterizam os empreendedores, os projetos de negócios gerados por eles podem alcançar altos níveis de adaptação às necessidades de impacto em períodos relativamente curtos. A capacidade e a velocidade de ação para o impacto são restritas principalmente para grandes empresas, por razões de diferentes tipos. Isso não significa que é um objetivo impossível de alcançar, mas que pode levar mais tempo e deve ser realizado com menos liberdade de ação do que muitos modelos de negócios empresariais. O ensino superior tem o potencial de treinar, motivar e acompanhar os empreendedores que desejam atravessar o caminho para alcançar o impacto, fornecendo as ferramentas e o apoio necessários para tentar criar soluções disruptivas para problemas comuns

Emprender en negocios de la economía circular: el caso BYOS

Undertaking recycling initiatives with a real impact is not so easy. Closing the loop to a circular economy business model carries additional complexity, but increases the potential for profitability and thus economic sustainability. It requires an operational and commercial structure, which is difficult for entrepreneurs to achieve. BYOS as a venture capital company created in 2016, works in the life cycle of vegetable oils. This article describes the itinerary realized, from the initial idea to the concretion of a circular economy business, with special emphasis on the role of the stakeholders involved. All of them fulfill several simultaneous roles in the circular economy process. From the fundamental role of the public sector, passing through consumers and citizens, erected, at the same time, as collaborators and auditors, to reaching the companies with whom they operate dailyEmprender en iniciativas de reciclaje con impacto real no es tarea fácil. Cerrar el circuito hacia un modelo de negocio de economía circular con lleva complejidad adicional, pero aumenta el potencial de rentabilidad y, por ende, de sustentabilidad económica. Se requiere una estructura operativa y comercial muchas difícil de alcanzar por emprendedores. BYOS es una empresa de capital emprendedor creada en 2016, que trabaja en el ciclo de vida de los aceites vegetales. El presente artículo describe el proceso recorrido, desde la idea inicial hasta la concreción de un negocio de economía circular, con especial énfasis en el rol de los stake holders involucrados. Todos ellos cumplen varios roles simultáneos en el proceso de la economía circular. Desde el papel fundamental del sector publico, pasando por los consumidores y ciudadanos, erigidos simultáneamente como colaboradores y auditores, hasta llegar a las empresas con quienes se opera diariamente.Empreender iniciativas de reciclagem com impacto real não é uma tarefa fácil. Fechar o ciclo de um modelo de negócios de economia circular implica complexidade adicional, mas aumenta o potencial de lucratividade e, portanto, de sustentabilidade econômica. É necessária uma estrutura operacional e comercial, difícil para os empreendedores. BYOS é uma empresa de capital de risco criada em 2016, que trabalha no ciclo de vida de óleos vegetais. Este artigo descreve o processo percorrido, desde a ideia inicial até a concretização de um negócio de economia circular, com ênfase especial no papel das partes envolvidas. Todos eles cumprem vários papéis simultâneos no processo de economia circular. Desde o papel fundamental do setor público, passando por consumidores e cidadãos, simultaneamente constituídos como colaboradores e auditores, até chegar às empresas com as quais operam diariamente

Assessing the impact of voting technologies on multi-party electoral outcomes: the case of Buenos Aires’ 2005 Congressional Election

This paper presents the first study on the impact of different voting technologies on election outcomes in multi-party elections, analyzing data from a large-scale voting experiment conducted in the 2005 congressional election in Buenos Aires, Argentina. Combining different regression models and matching methods, we estimate the effect of alternative voting technologies on the probability of support for the competing parties in the elections for congress and state legislature. The results of the different statistical techniques indicate that voters are extremely receptive to the information cues provided by the different voting technologies and associated ballot designs, and that particular voting devices have a significant impact on voter choice, systematically favoring some parties to the detriment of others. We conclude that the choice of alternative electronic voting devices might have considerable effect on electoral outcomes in multi-party electoral systems

Mechanical Ventilation and Clinical Outcomes in Patients with Acute Myocardial Infarction: A Retrospective Observational Study

Patients with acute myocardial infarction (AMI) and respiratory impairment may be treated with either invasive or non-invasive mechanical ventilation (MV). However, there has been little testing of non-invasive MV in the setting of AMI. Our objective was to evaluate the incidence and associated clinical outcomes of patients with AMI who were treated with non-invasive or invasive MV

Disruption of transitional stages in 24-h blood pressure recording in renal transplant recipients

Patients with kidney replacement exhibit disrupted circadian rhythms. Most studies measuring blood pressure use the dipper/non-dipper classification, which does not consider analysis of transitional stages between low and high blood pressure, confidence intervals nor shifts in the time of peak, while assuming subjective onsets of night and day phases. In order to better understand the nature of daily variation of blood pressure in these patients, we analyzed 24 h recordings from 41 renal transplant recipients using the non-symmetrical double-logistic fitting assessment which does not assume abruptness nor symmetry in ascending and descending stages of the blood pressure profile, and a cosine best-fitting regression method (Cosinor). Compared with matched controls, double-logistic fitting showed that the times for most transitional stages (ascending systolic and descending systolic, diastolic, and mean arterial pressure) had a wider distribution along the 24-h. The proportion of individuals without daily blood pressure rhythm in the transplanted group was larger only for systolic arterial pressure, and the amplitude showed no significant difference. Furthermore, the transplant recipient group had a less pronounced slope in descending systolic and ascending mean blood pressure. Cosinor analysis confirmed this phase-related changes, showing a wider distribution of times of peak (acrophases). We conclude that daily disruptions in renal transplant recipients can be explained not necessarily by an absence in diurnal variation, but also by changes in waveform-related parameters of the rhythm, and that alterations in the phase of the rhythm are the most consistent finding in these patients.Fil: Katz, Marcelo E.. Universidad Nacional de Quilmes; ArgentinaFil: Margulis, Fernando. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital General de Agudos Doctor Cosme Argerich; ArgentinaFil: Schiavelli, Rubén. Gobierno de la Ciudad Autónoma de Buenos Aires. Hospital General de Agudos Doctor Cosme Argerich; ArgentinaFil: Arias, Pablo. Universidad de Buenos Aires; ArgentinaFil: Head, Geoffrey A.. No especifíca;Fil: Golombek, Diego Andres. Universidad Nacional de Quilmes; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Renal Sympathetic Denervation and Quality of Life

ABSTRACTBackgroundRenal sympathetic denervation (RSD) is a promising strategy in the treatment of resistant hypertension. No studies have assessed the effect of RSD on quality of life in our country, which was the aim of this study.MethodsThe EuroQol5 Dimensions questionnaire (EQ5D5L) was chosen to evaluate quality of life in 10 patients undergoing RSD, and it was applied before and 3 months after the procedure.ResultsMean age was 47.3 ± 12 years and 90% of the patients were female. Baseline blood pressure was 187 ± 37.5/104 ± 18.5mmHg and the number of antihypertensive drugs was 7.6 ± 1.3. Before the procedure, the value assigned to health status was 37.5 ± 22.7, increasing at 3 months to 70.5 ± 20.9 (P = 0.01). In the follow-up, in addition to a decrease in the number of antihypertensive drugs (7.6 ± 1.3 vs. 6 ± 2.2; P = 0.05), a trend towards reduced levels of systolic blood pressure (187 ± 36mmHg vs 170 ± 44mmHg; P = 0.10) and diastolic blood pressure (104 ± 18mmHg vs 98 ± 20mmHg; P = 0.20) was observed. Health status improvement resulted from a reduction of problems related to mobility, usual activities, pain/discomfort and anxiety/depression. The magnitude of blood pressure reduction was not associated with improved quality in all of the patients. On the other hand, those who had a decrease in the number of antihypertensive drugs reported a better health status.ConclusionsPatients with resistant hypertension have poor health status scores. RSD improved quality of life in most patients. Further studies are required to confirm consistent benefits

Boletín NUESTRA AMÉRICA XXI - Desafíos y alternativas, num.13, noviembre 2017

Una excelente iniciativa del Grupo de Trabajo Crisis y economía mundial, coordinado por María Josefina Morales y Gabriela Roffinelli

Distúrbios no perfil circadianos de paramêtros hemodinâmicos na sepse grave e no choque séptico

Objective: Circadian disruptions in septic patients, and their relation to clinical outcome, have been described by several researchers. Methods: In this work we performed an individual analysis of hemodynamic variables (cardiac frequency and mean blood pressure) in three groups of patients: severe sepsis, septic shock and individuals housed in the same intensive care unit by causes other than inflammation or infection, as controls, during the first and the last 24 hours of their permanency in the critical care unit. Results: Although the cosinor analysis showed no difference in the proportion of patients that expressed a statistically significant circadian rhythm, during the first 24 hours, the phase of the variations were disrupted in both septic groups, being almost in anti-phase as compared to control individuals. During the last 24 hours, this variation was present only for mean blood pressure. No association of these changes could be related to outcome (surveillance). Conclusion: We conclude that disruptions in circadian rhythms in patients during severe stages of sepsis are related to phase better than presence/absence of variation, which could be crucial to time scheduled therapies.Objetivo: Distúrbios circadianos em pacientes sépticos e suas relações com desfechos clínicos têm sido descrito por diversos pesquisadores. Métodos: No presente trabalho nós conduzimos uma análise individual das variáveis hemodinâmicas (frequência cardíaca e pressão arterial média) em três grupos de pacientes: sepse grave, choque séptico e indivíduos internados na mesma unidade de tratamento intensivo por outras causas além de inflamação ou infecção, como controles, durante as primeiras e últimas 24 horas de suas permanências na unidade. Resultados: Embora a análise por meio do cosinor não tenha apresentando diferença na proporção de pacientes que expressaram um ritmo circadiano estatisticamente significativo, durante as primeiras 24h, a fase das variações estavam alteradas em ambos os grupos sépticos, sendo quase observada anti-fase quando comparados com indivíduos controle. Nas últimas 24h essa variação esteve presente apenas na pressão arterial média. Associações destas alterações não foram relacionadas a outros desfechos. Conclusão: Concluímos que alterações nos ritmos circadianos em pacientes durante estágios graves da sepse estão mais bem relacionados a fase do que à presença ou ausência de variações, as quais podem ser cruciais para o agendamento de terapias.Fil: Katz, Marcelo Esteban. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Cronobiología; ArgentinaFil: Rios, Fernando. Hospital Nacional Profesor Alejandro Posadas; ArgentinaFil: Sagardia, Judith. Hospital Nacional Profesor Alejandro Posadas; ArgentinaFil: Pezzola, Enrique. Hospital Nacional Profesor Alejandro Posadas; ArgentinaFil: Sobrero, Patricio Martín. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Cronobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Arias, Pablo. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Neuroendocrinología del Crecimiento y la Reproducción; ArgentinaFil: Yunk, Oscar. Sanatorio Trinity; ArgentinaFil: Maskin, Fernando. Hospital Nacional Profesor Alejandro Posadas; ArgentinaFil: Golombek, Diego Andrés. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Cronobiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin