10 research outputs found
An overview of medical image processing methods
Since human life is worthier than all things, efforts on virtual animation and visualization of human body’s viscera, without surgical interference to diagnose a disease is very important. Recently, modern medical instruments are able to produce views which can be used for better diagnoses and accurate treatment. Various standards were formed regarding these instruments and end products that are being used more frequently everyday. Personal computers (PCs) have reached a significant level in image processing, carried analysis and visualization processes which could be done with expensive hardware on doctors’ desktops. The next step is to try to find out proper solutions by software developers andengineers that help doctors to make decision by combining opportunities in these two scientific areas. The objective of the present study is to construct 3D models and present it to users on screen in personal computers by using data acquired from tomography and magnetic resonance instruments. In order to realize this objective, developing software is aimed. In the second and third sections, the datastructures and processing of 3D volumetric data in digital format, 3D visualization techniques and theoretical subjects about methods and algorithms used are explained. In the forth section, explanations on developing a software package for the realization of the objective of the study, its usage and information about software development tools used are given. In the last section, the determinations made at the end of trials in this study, difficulties met and recommendations obtained in the light of the trial results are presented
Postnatal LPS Challenge Impacts Escape Learning and Expression of Plasticity Factors Mmp9 and Timp1 in Rats: Effects of Repeated Training
Indiscriminate friendliness in foster children: Associations with attachment security, foster parents’ sensitivity, and child inhibitory control
Education and Child Studie
Indigenous media producers’ perspectives on objectivity, balancing community responsibilities and journalistic obligations
Pro-Apoptotic Effects of the Novel Tangeretin Derivate 5-Acetyl-6,7,8,4′-Tetramethylnortangeretin on MCF-7 Breast Cancer Cells
Toward Understanding How Early-Life Stress Reprograms Cognitive and Emotional Brain Networks
Vulnerability to emotional disorders including depression derives from interactions between genes and environment, especially during sensitive developmental periods. Adverse early-life experiences provoke the release and modify the expression of several stress mediators and neurotransmitters within specific brain regions. The interaction of these mediators with developing neurons and neuronal networks may lead to long-lasting structural and functional alterations associated with cognitive and emotional consequences. Although a vast body of work has linked quantitative and qualitative aspects of stress to adolescent and adult outcomes, a number of questions are unclear. What distinguishes ‘normal' from pathologic or toxic stress? How are the effects of stress transformed into structural and functional changes in individual neurons and neuronal networks? Which ones are affected? We review these questions in the context of established and emerging studies. We introduce a novel concept regarding the origin of toxic early-life stress, stating that it may derive from specific patterns of environmental signals, especially those derived from the mother or caretaker. Fragmented and unpredictable patterns of maternal care behaviors induce a profound chronic stress. The aberrant patterns and rhythms of early-life sensory input might also directly and adversely influence the maturation of cognitive and emotional brain circuits, in analogy to visual and auditory brain systems. Thus, unpredictable, stress-provoking early-life experiences may influence adolescent cognitive and emotional outcomes by disrupting the maturation of the underlying brain networks. Comprehensive approaches and multiple levels of analysis are required to probe the protean consequences of early-life adversity on the developing brain. These involve integrated human and animal-model studies, and approaches ranging from in vivo imaging to novel neuroanatomical, molecular, epigenomic, and computational methodologies. Because early-life adversity is a powerful determinant of subsequent vulnerabilities to emotional and cognitive pathologies, understanding the underlying processes will have profound implications for the world's current and future children