Guía de comunicación para situaciones de riesgo sanitario/ambiental para la municipalidad de Berisso

La siguiente guía está dirigida Autoridades Municipales de Berisso, Promotores de Salud, Directores de las Unidades Sanitarias y personal de las mismas. Esta compuesta por tres partes. En una primera instancia se brinda la información teórica necesaria para llevar a cabo herramientas de prevención y preparación de Riesgo Sanitarios/Ambiental para la Municipalidad de Berisso. La segunda parte será más práctica, dado que se podrán encontrar ejemplos de piezas comunicacionales junto a los tips para realizarlos y el tercer momento esta abocado al glosario técnico. Además brindará un boceto de cronograma de actividades y un cuadro de división de roles al momento de actuar. Al final de la guía se podrá encontrar una serie de planillas para los destinatarios. Estas tendrán diferentes usos: cuadros para armar su propia agenda de contactos, cuadros de autoevaluación con preguntas para realizarse y hasta hojas en blanco donde puedan escribir todo aquello que les es importante.Facultad de Periodismo y Comunicación Socia

Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease, characterized by progressive loss of spinal and cortical motor neurons, leading to muscular atrophy, respiratory failure, and ultimately death. There is no known cure, and the clinical benefit of the two drugs approved to treat ALS remains unclear. Novel disease-modifying therapeutics that are able to modulate the disease course are desperately needed. Our objective was to evaluate the efficacy and tolerability of Elysium Health's candidate drug EH301 in people with ALS (PALS).This was a single-center, prospective, double-blind, randomized, placebo-controlled pilot study. Thirty-two PALS were recruited thanks to the collaboration of the Spanish Foundation for ALS Research (FUNDELA). Study participants were randomized to receive either EH301 or placebo and underwent evaluation for 4 months. Differences between EH301 and placebo-treated participants were evaluated based on standard clinical endpoints, including the revised ALS functional rating scale (ALSFRS-R), forced vital capacity (FVC), and the Medical Research Council (MRC) grading scale.Compared to placebo, participants treated with EH301 demonstrated significant improvements in the ALSFRS-R score, pulmonary function, muscular strength, and in skeletal muscle/fat weight ratio. EH301 was shown to significantly slow the progression of ALS relative to placebo, and even showed improvements in several key outcome measures compared with baseline.This study provides evidence in support of the disease-modifying effects of EH301 for the treatment of ALS.Study Funded by the Catholic University San Vicente Mártir [grant 2017-216-001] and the University of Valencia [grant OTR2017-18255INVES] (Valencia, Spain). Elysium Health, Inc., NY (USA), provided the compounds tested in this study.Medicin

Ahora / Ara

La cinquena edició del microrelatari per l’eradicació de la violència contra les dones de l’Institut Universitari d’Estudis Feministes i de Gènere «Purificación Escribano» de la Universitat Jaume I vol ser una declaració d’esperança. Aquest és el moment en el qual les dones (i els homes) hem de fer un pas endavant i eliminar la violència sistèmica contra les dones. Ara és el moment de denunciar el masclisme i els micromasclismes començant a construir una societat més igualitària. Cadascun dels relats del llibre és una denúncia i una declaració que ens encamina cap a un món millor

Developmental stages during in vitro rooting of hardwood trees from material with juvenile and mature characteristics

Peer reviewe

Establishment of cryopreserved gene banks of European chestnut and cork oak

Cryopreservation of selected genotypes of Europeanchestnut and cork oak was carried out in two laboratories in a proect involving conservation of field collections. Plant material was selected on the basis of disease resistance (chestnut), growth habit, phytosanitary performance and cork quality (cork oak). The cryopreservation technique comprised vitrification of shoot apices isolated from in vitro stock shoot cultures (chestnut) and somatic embryos (cork oak). Forty three out 46 chestnut genotypes assayed survived the freezing process, but only 63% recovered their capacity to produce new shoots. After completion of multiplication and rooting steps, the surviving shoots produced plants that were morphologically identical to those derived from non-supercooled material. All 51 cork oak genotypes withstood freezing and were able to produce new somatic embryos through a process of secondary embrygenesis. Multiplication and germination of the recovered embryos enabled production of plants that were morphologically identical to thse derived from non‐supercooled material. In light of the results obtained, long-term cryopreservation of these species is feasible, thereby ensuring conservation of valuable genotypes during field Peer reviewe

Improved organogenic capacity of shoot cultures from mature pedunculate oak trees through somatic embryogenesis as rejuvenation technique

Theoretically, complete rejuvenation of mature trees should occur through somatic embryogenesis, however, this has not been extensively studied. The main objective of the present study was to increase the efficiency of in vitro clonal propagation for mature Quercus robur (100–300 years old), by induction of somatic embryogenesis as rejuvenation step prior to establishment of shoot culture through micropropagation of somatic embryo-derived plantlets. Shoot culture lines of “mature” origin were established from epicormic shoots of two centenarian oak genotypes (Sainza and CR-0) and maintained by axillary shoot proliferation. Embryogenic lines were also initiated from epicormic leaf explants of the same genotypes and maintained by secondary somatic embryogenesis. Although the frequency of somatic embryo conversion into plantlets was low in pedunculate oak, shoot culture lines could be established and maintained by axillary branching from several germinated somatic embryos. For each genotype and shoot culture line of the two origins (mature tree and somatic plantlets), shoot multiplication rate and elongation as well as rooting ability parameters were compared. Compared with “mature-origin” shoot cultures and after more than one year propagation in vitro, shoot lines established from somatic plantlets produced a significantly higher proportion of elongated, rootable shoots (from 26.0–31.6 to 36.8–40.5%) with increased rooting ability (from 3.3–45.6% to 23.2–89.8%). In the case of 300-year-old Sainza genotype such a high organogenic capacity was similar to shoot cultures initiated from basal sprouts. Basal sprouts are considered as “mature” material that retains juvenile characteristics compared with epicormic shoots forced from crown branches. Somatic embryogenesis only slightly improved plant regeneration of shoot cultures from basal sprouts, thus validating their use as “juvenile control”. The present results provide evidence that some rejuvenation occurred during the process of somatic embryogenesis and resulted in improved shoot growth and rooting of somatic embryo-derived culture compared with “mature” shoot culture. The results reported in this study might be useful in embryogenic systems with low plant conversion rates. The proposed experimental model might also be useful in finding molecular markers of plant ontogeny.This research was partially funded by Xunta de Galicia and Consejo Superior de Investigaciones Científicas (Spain) through the projects 09MRU002400PR and PIE200940I011, respectively.Peer reviewe

Biochemical characteristics of chestnut shoots related to in vitro multiplication and rooting capacities

In vitro shoot cultures from stump sprouts and basal shoots of 15 to 80-year-old chestnut proliferated and rooted with rates higher than those originating from crown material of the same tree. A higher amount of anthocyanins was recorded in basal shoot cultures than in crown cultures. The concentration of N-benzyl-aminopurine (BAP) introduced to the growth medium modified the content of anthocyanins in the shoots grown in vitro. A higher content of endogenous cytokinins was measured in crown shoots than in basal shoots before in vitro establishment. In vitro shoots from two of the three clones examined showed the same relationship at the end of the multiplication cycle. No direct relationship could be found between peroxidase activity (estimated in shoots before in vitro establishment and at the end of multiplication cycle), or the absolute amounts of indole-3-acetic acid (IAA) or the total auxin content (at the end of the multiplication cycle) and the rooting capacities of either type of shoots. There was however a direct relationship between the ratio of IAA/cytokinins and the rooting abilities.The present collaboration was established in the framework of the ECLAIR project AGRE 0067 on broad leaf hardwood. The EC are gratefully acknowledged. Thanks are also due to CICYT, Spain (Project AGF92-1055-CE) and DGICYT (Project P892-0017), for partial financial support.Peer reviewe

Polypeptide Markers Differentiating Juvenile and Adult Tissues in Chestnut

Differences were observed between the polypeptide contents of in vitro shoot cultures derived from upper branches (adult material) and basal shoots (juvenile material) of the same chestnut tree. Cultures derived from mature crown growth yielded two polypeptide bands that were not afforded by cultures derived from juvenile basal shoots. Since all cultures were derived from the same tree the polypeptide differences appear to reflect the ontogenetic age of the starting material.Peer reviewe

Developmental stages during the rooting of in-vitro-cultured Quercus robur shoots from material of juvenile and mature origin

In-vitro-cultured shoots of clones initiated from shoots of the basal parts (BS) and the crown (C) of two mature Quercus robur L. trees were subjected to rooting experiments to relate rooting with shoot topophysical origin. The BS shoots exhibited morphologically juvenile characteristics and rooted more easily after indole-3-butyric acid (IBA) treatment than C shoots. When naphthylphthalamic acid (NPA) was applied to BS shoots, rooting capacity decreased and root emergence was delayed at least 2 days compared with shoots treated with IBA only. During the first days of the rooting process, endogenous indole-3-acetic acid (IAA) concentration was higher in C shoots than in BS shoots, regardless of whether the shoots were treated with NPA. Mitotic figures were observed in cells from the basal part of both BS and C shoots 24 h after IBA treatment. After 4 days of IBA treatment, the occurrence of histological events differed between BS shoots and C shoots. Cells of BS shoots became meristematic, giving rise to meristemoids and root primordia, whereas no differentiation of root meristemoids occurred in cells of C shoots. Thus, although adult oak material (C shoots) is capable of responding to the initial stimulus of auxin during the adventitious rooting process, the endogenous IAA concentration is not the factor limiting rooting in adult material.This study was partially supported by CDI, MCYT, Spain (Project No. AGL200-0297-CO3-02). G.A. acknowledges the support of a CONACYT/AECI fellowship during this work.Peer reviewe