33 research outputs found
On the aspectuality of the individual-level / stage-level dichotomy
This paper addresses how the contrast known as Individual-‐Level/Stage-‐Level (IL/SL) is implemented in the grammar. More specifically, the paper is a critical assessment of the view that the IL/SL distinction is an aspectual distinction. The empirical data I will be using to probe into the IL/SL dichotomy is the contrast between the copular verbs in Spanish ser/estar. I will argue that the Spanish copular contrast reflexes the IL/SL dichotomy and that this dichotomy cannot be reduced to an aspectual difference in the ways it has been proposed in previous literature. Concurring with other authors I will argue that IL/SL-‐ness ensues from a different syntactic composition, very likely from different heads of prepositional nature, which can be argued to carry aspectual value. Crucially, however, this aspectual heads do not seem to translate into differences at the level of viewpoint or situation aspect in any relevant sense, as has been proposed in the literature
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Mini Course on the Syntax & Semantics of Aspect
This is an invited lecture about the theory of Aspect I have proposed in published work and the fundamentals underlying it. The lecture addressed the formal analysis of Aspect, its nature, the algorithms that give rise to the right interpretation of sentences and the difficulties of capturing these across languages. It was given to established scholars and postgraduate students working on the acquisition on Aspect the 19th January of 2018 at the University of Southampton
Pharmacological effects of mitraphylline from Uncaria tomentosa in primary human monocytes: Skew toward M2 macrophages
© 2015 Elsevier Ireland Ltd. All rights reserved. Ethnopharmacological relevance Uncaria tomentosa (Willdenow ex Roemer & Schultes) DC. (Rubiaceae) is a Peruvian thorny liana, commonly known as >cat's claw>, and traditionally used in folk medicine to deal with several inflammatory diseases. Mitraphylline (MTP) is the most abundant pentacyclic oxindolic alkaloid (POA) from U. Tomentosa and has been reported to modify the inflammatory response. Herein, we have sought to identify the mechanisms underlying this modulatory effect of MTP on primary human monocytes and its ability to regulate differentiation processes on human primary monocyte and monocyte-derived macrophages. Material and methods In vitro studies with human primary monocytes and monocyte-derived macrophages were performed. Monocytes and M0 macrophages were exposed to MTP (25 μM) and LPS (100 ng/mL). M0 macrophages were polarized to M1 and M2 phenotypes in the absence or presence of MTP. The activation state of monocytes/macrophages was assessed by flow cytometry, gene expression and protein analysis of different specific markers. Results In human primary monocytes, the incubation of MTP for 24 h reduced the number of classical (CD14++CD16-) and intermediate (CD14++CD16+) subsets when compared to untreated or LPS-treated cells. MTP also reduced the chemotactic capacity of human primary monocytes. In addition, MTP promoted the polarization of M0 macrophages toward an anti-inflammatory M2 phenotype, the abrogation of the release of pro-inflammatory cytokines such as TNFα, IL-6 or IL-1β, as well as the restoration of markers for M2 macrophages in LPS-treated M1 macrophages. Conclusions Our results suggest that MTP may be a key modulator for regulating the plasticity of monocytes/macrophages and the attenuation of the inflammatory response.This work was supported by the University of Seville, “V Own Research Plan” contract to BB and QA. MS has the benefit of a FPI fellowship (BES-2012–056104) of MICINN.Peer Reviewe
The construction of viewpoint aspect: the imperfective revisited
This paper argues for a constructionist approach to viewpoint Aspect by exploring the idea that it does not exert any altering force on the situation-aspect properties of predicates. The proposal is developed by analyzing the syntax and semantics of the imperfective, which has been attributed a coercer role in the literature as a de-telicizer and de-stativizer in the progressive, and as a de-eventivizer in the so-called ability (or attitudinal) and habitual readings. This paper proposes a unified semantics for the imperfective, preserving the properties of eventualities throughout the derivation. The paper argues that the semantics of viewpoint aspect is encoded in a series of functional heads containing interval-ordering predicates and quantifiers. This richer structure allows us to account for a greater amount of phenomena, such as the perfective nature of the individual instantiations of the event within a habitual construction or the nonculminating reading of perfective accomplishments in Spanish. This paper hypothesizes that nonculminating accomplishments have an underlying structure corresponding to the perfective progressive. As a consequence, the progressive becomes disentangled from imperfectivity and is given a novel analysis. The proposed syntax is argued to have a corresponding explicit morphology in languages such as Spanish and a nondifferentiating one in languages such as English; however, the syntax-semantics underlying both of these languages is argued to be the same
Subject inversion in non-native Spanish
This study presents new empirical evidence on the L2 acquisition of Spanish SV–VS contrasts, a syntax-pragmatics interface phenomenon. Results from a context-dependant preference task involving unergative and unaccusative verbs in different focus situations (broad and narrow focus) reveal that beginner and intermediate English speakers prefer SV in all contexts. In contrast, advanced learners, who clearly know that VS is possible in Spanish, show a pattern of optionality with unergative verbs (in both broad and narrow focus contexts), whereas VS is correctly preferred with unaccusative verbs in both broad and narrowly-focused contexts. We argue that these results can be explained by a representational deficit according to which the VS order is overgeneralised to unergative verbs regardless of the discursive situation. We argue that learners’ overuse of VS structures is exacerbated by the lack of clear evidence for the use of SV and VS forms in the native input
Optionality in L2 grammars: the acquisition of SV/VS contrast in Spanish
This study examines the L2 acquisition of word order variation in Spanish by three groups of L1 English learners in an instructed setting. The three groups represent learners at three different L2 proficiencies: beginners, intermediate and advanced. The aim of the study is to analyse the acquisition of word order variation in a situation where the target input is highly ambiguous, since two
apparent optional forms exist in the target grammar, in order to examine how the optionality is disambiguated by learners from the earlier stages of learning to the more advanced. Our results
support the hypothesis that an account based on a discourse-pragmatics deficit cannot satisfactorily explain learners’ non-targetlike representations in the contexts analysed in our study
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Individuals in time: tense, aspect and the individual/stage distinction
This monograph investigates the temporal properties of those predicates referring to individuals – the so-called individual-level (IL) predicates – in contrast to those known as stage-level (SL) predicates. Many of the traditional tenets attributed to the IL/SL dichotomy are not solidly founded, this book claims, as it examines current theoretical issues concerning the syntax/semantics interface such as the relation between semantic properties of predicates and their syntactic structure. By using the contrast found in Spanish copular clauses (ser vs. estar), Individuals in Time shows that the conception of IL predicates as permanent and stative cannot be maintained. The existence of nonstative IL predicates is demonstrated through analyzing the correlation between the syntactic presence of certain projections (specifically, prepositional complements) and process-like aspect properties. This detailed examination of IL predicates in the domains of inner aspect, outer aspect, and tense will be welcomed by scholars and students with an interest in event structure, tense, and aspect
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[Book Review] The role of formal features in second language acquisition - edited by J. Liceras, H. Zobl, and H. Goodluck
Book review of: J. Liceras, H. Zobl, and H. Goodluck (eds.), 2008, The Role of Formal Features in Second Language Acquisition. London/New York: Lawrence Erlbaum Associates, 577 pages, ISBN: 0-8058-5354-5