25 research outputs found

    Influence of live cells or cells extract of Saccharomyces cerevisiae on in vitro gas production of a total mixed ration

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    In vitro gas production An interaction effect was observed (P=0.009) between treatment type and treatment dose for the asymptotic GP without interaction effects (P>0.05) for the rate of GP and the initial delay before gas production begins. In general, incubation of yeast CE improved (P=0.0007) the asymptotic GP compared to control and yeast LC. In both of CE and LC, the low and the intermediate doses were morelive cells (LC) or cells extract (CE) on in vitro gas production (GP) kinetics and ruminal fermentation parameters of a total mixed ration (TMR) consisting of commercial concentrate and alfalfa hay [1:1 dry matter (DM)] as a substrate was studied. The TMR was incubated with CE at 1, 2 and 4 mg/g or LC at 0.3, 0.6 and 0.9 mg/g DM for 96 h. Rumen GP was recorded after 6, 12, 19, 24, 48, 72 and 96 h of incubation. Interaction effects were observed (P<0.01) between treatment type and yeast dose for the asymptotic GP and methane (CH4) production. Incubation of yeast CE improved (P<0.01) the asymptotic GP compared to control and LC with greater effects (P<0.01) for the low and the intermediate doses. Yeast CE treatment was more effective (P<0.01) in GP than both of LC and control treatments with greater effect (P<0.01) for the low and the intermediate doses. Treatment type and yeast dose affected (P<0.01) CH4 production, metabolisable energy (ME), and short chain fatty acids (SCFA) without affecting in vitro DM degradability (IVDMD). Higher values (P<0.01) of CH4, ME, SCFA and IVDMD were observed for the yeast CE treatment. It could be concluded that adding yeast S. cerevisiae (CE and LC extract) improved GP and ruminal fermentation parameters, where CE at 0.3 and 0.6 mg/g DM was more effective than the yeast LC

    ELOVL6 Genetic Variation Is Related to Insulin Sensitivity: A New Candidate Gene in Energy Metabolism

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    BACKGROUND: The elongase of long chain fatty acids family 6 (ELOVL6) is an enzyme that specifically catalyzes the elongation of saturated and monounsaturated fatty acids with 12, 14 and 16 carbons. ELOVL6 is expressed in lipogenic tissues and it is regulated by sterol regulatory element binding protein 1 (SREBP-1). OBJECTIVE: We investigated whether ELOVL6 genetic variation is associated with insulin sensitivity in a population from southern Spain. DESIGN: We undertook a prospective, population-based study collecting phenotypic, metabolic, nutritional and genetic information. Measurements were made of weight and height and the body mass index (BMI) was calculated. Insulin resistance was measured by homeostasis model assessment. The type of dietary fat was assessed from samples of cooking oil taken from the participants' kitchens and analyzed by gas chromatography. Five SNPs of the ELOVL6 gene were analyzed by SNPlex. RESULTS: Carriers of the minor alleles of the SNPs rs9997926 and rs6824447 had a lower risk of having high HOMA_IR, whereas carriers of the minor allele rs17041272 had a higher risk of being insulin resistant. An interaction was detected between the rs6824447 polymorphism and the intake of oil in relation with insulin resistance, such that carriers of this minor allele who consumed sunflower oil had lower HOMA_IR than those who did not have this allele (P = 0.001). CONCLUSIONS: Genetic variations in the ELOVL6 gene were associated with insulin sensitivity in this population-based study

    El reto de la inclusión de los Objetivos de Desarrollo Sostenible en la formación inicial de profesores de secundaria: creación del MOOC curso cero sobre educación y ODS, inclusión en asignaturas y en trabajos fin de máster

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    Memoria ID-041. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2021-2022

    Diseño de una estrategia para la formación en Competencias Transversales en la Universidad de Salamanca

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    Memoria ID-0184. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2009-2010.En la convocatoria de Innovación Docente de la Universidad de Salamanca para realizar proyectos de esta índole en el curso 2009‐20010, se presentó el proyecto que lleva por título “Diseño de una estrategia para la formación en Competencias Transversales en la Universidad de Salamanca” cuyo objetivo fundamental era elaborar una estrategia para la formación y planificar la oferta formativa en Competencias Transversales desde el Servicio de Formación Continua de la Universidad de Salamanca

    Development and Validation of the Depression Inventory for Type 1 Diabetes (DID-1)

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    People with type 1 diabetes (T1D) are more likely to have depression than the general population and their prognosis is worse. Unfortunately, the characteristics of persons with T1D lead to inadequate screening for depression in this population. To aid in the detection of depression in this population, this study was undertaken to develop a depressive symptoms assessment instrument specific to patients with T1D and to examine its psychometric properties. A total of 207 people with T1D participated in this study. The reliability of the new scale was assessed using Cronbach&rsquo;s alpha and the Spearman-Brown split-half coefficient. The Depression Inventory for type 1 Diabetes (DID-1), composed of 45 items on a Likert scale (1&ndash;7), shows high internal and temporal consistency, as well as adequate concurrent, convergent and discriminant validity. Factor analysis identified 7 factors (Symptoms of depression, Diminished interest, Hopelessness and dissatisfaction, Guilt, Fear, frustration and irritability, Defenselessness, and Interference in daily life) that explained 61.612% of the total variability. The cut-off score for diagnosis was set at 155 points. It was concluded that the DID-1 scale is a reliable, valid and useful tool for the assessment of depressive symptoms, eliminating the bias of other nonspecific diabetes scales
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