The Research on the Relationship between the Social Support and Mental Health Status of the Rural Elderly Five Years after 5.12 Earthquake

Objective: To understand the mental health status and social support status of the elderly population in rural areas after 5.12 earthquake disaster and its influence on mental health status. Methods: 195 rural elderly in Pengzhou mountainous areas (Longmen mountain town, Ci feng town, Xiao yudong town, Tongji town, Bailu town, Xinxing town) 6 towns were investigated by random questionnaire, self-made demographic scale, Symptom self-rating Scale (SCL-90) and Social Support scale. Results: (1) The social support status of the rural elderly was good, but the mental health levels were significantly lower than the national norm (p<0.001), and the prevalence of psychological symptoms was 6.16% (12/195). (2) The total score of social support and scores of subjective support were negatively correlated with the depression factors of mental health (r subjective support = -0.167 p<0.05, r social support total mark = -0.168 p<0.05), and the subjective support had a predictive effect on depression (β=-0.086, p<0.05). Conclusion: Although the detection rate of mental health of rural elderly in the five years after the earthquake is not high, the score of all dimensions of scl-90 is significantly lower than the norm, and the good social support will alleviate mental health problems

Candidate Regulators of Dyslipidemia in Chromosome 1 Substitution Lines Using Liver Co-Expression Profiling Analysis

Dyslipidemia is a major risk factor for cardiovascular disease. Although many genetic factors have been unveiled, a large fraction of the phenotypic variance still needs further investigation. Chromosome 1 (Chr 1) harbors multiple gene loci that regulate blood lipid levels, and identifying functional genes in these loci has proved challenging. We constructed a mouse population, Chr 1 substitution lines (C1SLs), where only Chr 1 differs from the recipient strain C57BL/6J (B6), while the remaining chromosomes are unchanged. Therefore, any phenotypic variance between C1SLs and B6 can be attributed to the differences in Chr 1. In this study, we assayed plasma lipid and glucose levels in 13 C1SLs and their recipient strain B6. Through weighted gene co-expression network analysis of liver transcriptome and "guilty-by-association" study, eight associated modules of plasma lipid and glucose were identified. Further joint analysis of human genome wide association studies revealed 48 candidate genes. In addition, 38 genes located on Chr 1 were also uncovered, and 13 of which have been functionally validated in mouse models. These results suggest that C1SLs are ideal mouse models to identify functional genes on Chr 1 associated with complex traits, like dyslipidemia, by using gene co-expression network analysis

FusionFormer: A Multi-sensory Fusion in Bird's-Eye-View and Temporal Consistent Transformer for 3D Objection

Multi-sensor modal fusion has demonstrated strong advantages in 3D object detection tasks. However, existing methods that fuse multi-modal features through a simple channel concatenation require transformation features into bird's eye view space and may lose the information on Z-axis thus leads to inferior performance. To this end, we propose FusionFormer, an end-to-end multi-modal fusion framework that leverages transformers to fuse multi-modal features and obtain fused BEV features. And based on the flexible adaptability of FusionFormer to the input modality representation, we propose a depth prediction branch that can be added to the framework to improve detection performance in camera-based detection tasks. In addition, we propose a plug-and-play temporal fusion module based on transformers that can fuse historical frame BEV features for more stable and reliable detection results. We evaluate our method on the nuScenes dataset and achieve 72.6% mAP and 75.1% NDS for 3D object detection tasks, outperforming state-of-the-art methods

Numerical Simulation of Hot Accretion Flows (II): Nature, Origin, and Properties of Outflow and Their Possible Observational Applications

Previous hydrodynamical (HD) and magnetohydrodynamical (MHD) numerical simulations of hot accretion flows have shown that the mass accretion rate decreases with decreasing radius. Two models have been proposed to explain this result. In the ADIOS model, the inward decrease of accretion rate is because of the loss of gas in the outflow. In the CDAF model, the gas is assumed to be locked in convective eddies, which results in the inward decrease of the accretion rate. We investigate the nature of inward decrease of accretion rate using HD and MHD simulations. We calculate various properties of inflow and outflow, including the mass flux, radial and rotational velocities, temperature, and the Bernoulli parameter ($Be$). Systematic and significant differences between inflow and outflow are found. These results suggest that the inflow and outflow are not dominated by convective turbulence, but are systematic inward and outward motion. We have also analyzed the convective stability of MHD accretion flow and found that they are convectively stable. These results indicate that the ADIOS scenario is favored. The different properties of inflow and outflow also suggest that the mechanisms of producing outflow in HD and MHD flows are buoyancy and centrifugal force associated with the magnetic field, respectively. The latter mechanism is similar to the Blandford & Payne mechanism. We also study the effect of initial conditions in the simulations. We find that the value of $Be$ is mainly determined by the value of $Be$ of the initial condition. We discuss some possible observational applications of our outflow model. These observations include the Fermi bubble observed in the Galaxy center, and winds widely observed in AGNs and black hole X-ray binaries.Comment: 24 emulateapj pages, 15 figures; one figure and some references added, conclusion unchanged; ApJ in pres

Improved fractional Trudinger-Moser inequalities on bounded intervals and the existence of their extremals

Let II be a bounded interval of R{\mathbb{R}} and λ1(I){\lambda }_{1}\left(I) denote the first eigenvalue of the nonlocal operator (−Δ)14{(-\Delta )}^{\tfrac{1}{4}} with the Dirichlet boundary. We prove that for any 0⩽α<λ1(I)0\leqslant \alpha \lt {\lambda }_{1}(I), there holds supu∈W012,2(I),‖(−Δ)14u‖22−α∥u∥22≤1∫Ieπu2dx<+∞,\mathop{\sup }\limits_{u\in {W}_{0}^{\frac{1}{2},2}(I),\Vert {\left(-\Delta )}^{\tfrac{1}{4}}u{\Vert }_{2}^{2}-\alpha {\parallel u\parallel }_{2}^{2}\le 1}\mathop{\int }\limits_{I}{e}^{\pi {u}^{2}}{\rm{d}}x\lt +\infty , and the supremum can be attained. The method is based on concentration-compactness principle for fractional Trudinger-Moser inequality, blow-up analysis for fractional elliptic equation with the critical exponential growth and harmonic extensions

Multiple Nontrivial Solutions for a Class of Biharmonic Elliptic Equations with Sobolev Critical Exponent

In this paper, we study the existence and multiplicity of nontrivial solutions for a class of biharmonic elliptic equation with Sobolev critical exponent in a bounded domain. By using the idea of the previous paper, we generalize the results and prove the existence and multiplicity of nontrivial solutions of the biharmonic elliptic equations