Spindle cell sarcoma of uterus-a rare tale

Uterine sarcoma are a heterologous group of are malignancies and account for one-tenth of uterine malignancies. Presentation of uterine sarcomas are usually very non-specific and varies with the histological sub type. Here we discuss a rare case of spindle cell neoplasm which presented to us with massive abdominal enlargement.she had no pressure symptoms. Decision to perform an exploratory laparotomy was taken given the high suspicion of ovarian tumour. Diagnosis was confirmed after histopathological report. Patient is doing well on follow up.

Regional characteristics relevant to advanced technology cogeneration development

To assist DOE in establishing research and development funding priorities in the area of advanced energy conversion technoloy, researchers at the Jet Propulsion Laboratory studied those specific factors within various regions of the country that may influence cogeneration with advanced energy conversion systems. Regional characteristics of advanced technology cogeneration possibilities are discussed, with primary emphasis given to coal derived fuels. Factors considered for the study were regional industry concentration, purchased fuel and electricity prices, environmental constraints, and other data of interest to industrial cogeneration

Anti-inflammatory drugs with therapeutic effects and drug regulators

For prostaglandin production, the enzyme cyclooxygenase (COX) is required. The two COX isoforms are constitutive COX-1 (which is responsible for physiological functions) and inducible COX-2 (involved in inflammation). COX inhibition explains both the medicinal (inhibition of COX-2) and negative effects (inhibition of COX-1) effects of non-steroidal anti-inflammatory medicines (NSAIDs). Nonsteroidal anti-inflammatory medicines (NSAIDs) act by blocking the enzyme cyclooxygenase (COX), which produces prostaglandins (PGs). To a greater or lesser extent, they share similar side effects, such as stomach and renal toxicity. According to a recent study, there are at least two COX isoenzymes. COX-1 is a naturally occurring enzyme that creates prostaglandins (PGs), which protect the stomach and kidneys. Aspirin's well-known anti-cancer impact could also be related to its influence on COX-2, which is expressed in this condition. As a result, selective COX-2 inhibitors may have new therapeutic potential as anticancer drugs, as well as in preventing premature labor and maybe reducing the progression of Alzheimer's disease

Development of a Direct Contact Heat Exchanger, Phase 1 Study Report

Electric power generation from geothermal brine requires, first, bringing the hot brine to the surface and then converting the heat to electric power. Binary conversion schemes were proposed, with the heat transfer between the brine and the working organic fluid taking place in a conventional tube and shell heat exchanger. If the brine is heavily laden with dissolved solids, however, solids buildup on the heat exchanger surfaces leads to a considerable degree of fouling and an accompanying drop in performance is experienced. A possible solution to this problem is the use of a direct contact exchanger with the secondary fluid power cycle. The proposed concept involves the formation of fluid sheets and bells as heat angles. Results of a study concerning the fluid mechanics of such surfaces are given

Location aware event driven multipath routing in Wireless Sensor Networks: Agent based approach

AbstractWireless Sensor Networks (WSNs) demand reliable and energy efficient paths for critical information delivery to sink node from an event occurrence node. Multipath routing facilitates reliable data delivery in case of critical information. This paper proposes an event triggered multipath routing in WSNs by employing a set of static and mobile agents. Every sensor node is assumed to know the location information of the sink node and itself. The proposed scheme works as follows: (1) Event node computes the arbitrary midpoint between an event node and the sink node by using location information. (2) Event node establishes a shortest path from itself to the sink node through the reference axis by using a mobile agent with the help of location information; the mobile agent collects the connectivity information and other parameters of all the nodes on the way and provides the information to the sink node. (3) Event node finds the arbitrary location of the special (middle) intermediate nodes (above/below reference axis) by using the midpoint location information given in step 1. (4) Mobile agent clones from the event node and the clones carry the event type and discover the path passing through special intermediate nodes; the path above/below reference axis looks like an arc. While migrating from one sensor node to another along the traversed path, each mobile agent gathers the node information (such as node id, location information, residual energy, available bandwidth, and neighbors connectivity) and delivers to the sink node. (5) The sink node constructs a partial topology, connecting event and sink node by using the connectivity information delivered by the mobile agents. Using the partial topology information, sink node finds the multipath and path weight factor by using link efficiency, energy ratio, and hop distance. (6) The sink node selects the number of paths among the available paths based upon the criticalness of an event, and (7) if the event is non-critical, then single path with highest path weight factor is selected, else multiple paths are selected for the reliable communication. The performance of the proposed scheme is tested in terms of performance parameters such as packet delivery ratio, energy consumption, latency, and overhead

Abraham Maslow’s Notion of Self- Actualization in Philip Roth’s American Pastoral

This article makes the argument more specifically on the humanistic psychology; a vibrant movement of the late 1950s; emphasizing the qualities, growth, need, creativity, and motivation of an individual. Philip Roth’s American Pastoral was an American classic, a novel of American culture. It is not only a biography, but an intensive interpretation of the fall of American dream. The author demonstrates the American Pastoral from the humanistic point of view. This paper attempts to analyse the humanistic attitudes and values in the novel American Pastoral. The process from the basic to the being needs in the novel is being critically expressed within the framework of the humanistic psychology

Atypical presentation and complications of term pregnancy with Mullerian duct anomaly: two case reports

Mullerian duct anomalies present as vague and overlapping features with other gynaecological conditions or may remain asymptomatic. These can lead to various obstetrical complications such as miscarriage, fetal growth restriction, preterm birth, abnormal placental implantation, malpresentation, increased risk of cesarean section, retained placenta and others. We hereby presented two cases with term pregnancy in women with Mullerian duct anomaly and the obstetrical complications they had. The first case landed up in a cesarean section at term due to breech presentation as a result of MDA. The second case had a vaginal delivery followed by entrapped retained placenta due to MDA, which had to be removed in piece meal. We hereby discussed the possible pathophysiology leading to these obstetrical complications in MDA pregnancies. MDA can lead to complications in pregnancy and previously undiagnosed women when detected with MDAs should be informed about complications and treatment options before and during pregnancy, for better maternal and neonatal outcomes