Complicaciones vasculares tras cateterismo cardíaco

Objetivos: Establecer la incidencia de complicaciones vasculares tras un cateterismo cardíaco y determinar los factores que influyen en la aparición de los mismos. Material y métodos: Revisión retrospectiva de los 3723 cateterismos cardíacos realizados en nuestro hospital durante un período de 50 meses. Se recogieron 32 traumatismos vasculares, distribuidos entre pseudoaneurismas, hematomas o hemorragias incoercibles, fístulas arteriovenosas e isquemias agudas por trombosis arterial. Se realizó un analisis estadístico mediante tablas de contingencia (método de Jicuadrado, con corrección de Yates). Resultados: La incidencia anual de traumatismos vasculares se encuentra alrededor del 1 %. La incidencia de traumatismos tras un cateterismo terapéutico es ligeramente superior a la incidencia tras un cateterismo diagnóstico, sin presentar diferencias significativas. La edad media del grupo de pacientes con traumatismo vascular (grupo estudio) es de 64'2 ± 1 '9 años, ligeramente superior a la edad media del grupo sin traumatismo vascular (grupo control) (61 '1 - 0'2 años). En ambos grupos predominaban los varones, pero en el grupo estudio dicho predominio es sensi blemente inferior (p 0'012) . En el grupo estudio la incidencia de pacientes obesos es superior con respecto al grupo control (p 0'024). El abordaje por vía humeral (p 0'03), el diametro de cateter mayor al 8F (p 0'001) Y la anticoagulación tras el cateterismo (p<0'001) son factores favorecedores par la aparición de un traumatismo vascular tras un cateterismo cardíaco

Circulating carotenoids are associated with favorable lipid and fatty acid profiles in an older population at high cardiovascular risk

Carotenoid intake has been reported to be associated with improved cardiovascular health, but there is little information on actual plasma concentrations of these compounds as biomarkers of cardiometabolic risk. The objective was to investigate the association between circulating plasma carotenoids and different cardiometabolic risk factors and the plasma fatty acid profile. This is a cross-sectional evaluation of baseline data conducted in a subcohort (106 women and 124 men) of an ongoing multi-factorial lifestyle trial for primary cardiovascular prevention. Plasma concentrations of carotenoids were quantified by liquid chromatography coupled to mass spectrometry. The associations between carotenoid concentrations and cardiometabolic risk factors were assessed using regression models adapted for interval-censored variables. Carotenoid concentrations were cross-sectionally inversely associated with serum triglyceride concentrations [-2.79 mg/dl (95% CI: -4.25, -1.34) and -5.15 mg/dl (95% CI: -7.38, -2.93), p-values = 0.0002 and <0.00001 in women and men, respectively], lower levels of plasma saturated fatty acids [-0.09% (95% CI: -0.14, -0.03) and -0.15 % (95% CI: -0.23, -0.08), p-values = 0.001 and 0.0001 in women and men, respectively], and higher levels of plasma polyunsaturated fatty acids [(0.12 % (95% CI: -0.01, 0.25) and 0.39 % (95% CI: 0.19, 0.59), p-values = 0.065 and 0.0001 in women and men, respectively] in the whole population. Plasma carotenoid concentrations were also associated with higher plasma HDL-cholesterol in women [0.47 mg/dl (95% CI: 0.23, 0.72), p-value: 0.0002], and lower fasting plasma glucose in men [-1.35 mg/dl (95% CI: -2.12, -0.59), p-value: 0.001]. Keywords: Mediterranean diet; PREDIMED-plus study; cardiovascular health; liquid chromatography; mass spectrometry; plasma carotenoids