3,681 research outputs found
Group-Average Observables as Controls for Sorting on Unobservables When Estimating Group Treatment Effects: The Case of School and Neighborhood Effects
We consider the classic problem of estimating group treatment effects when individuals sort based on observed and unobserved characteristics. Using a standard choice model, we show that controlling for group averages of observed individual characteristics potentially absorbs all the across-group variation in unobservable individual characteristics. We use this insight to bound the treatment effect variance of school systems and associated neighborhoods for various outcomes. Across four datasets, our conservative estimates indicate that a 90th versus 10th percentile school system increases high school graduation and college enrollment probabilities by at least 0.047 and 0.11. Other applications include measurement of teacher value-added
A simplicial gauge theory
We provide an action for gauge theories discretized on simplicial meshes,
inspired by finite element methods. The action is discretely gauge invariant
and we give a proof of consistency. A discrete Noether's theorem that can be
applied to our setting, is also proved.Comment: 24 pages. v2: New version includes a longer introduction and a
discrete Noether's theorem. v3: Section 4 on Noether's theorem has been
expanded with Proposition 8, section 2 has been expanded with a paragraph on
standard LGT. v4: Thorough revision with new introduction and more background
materia
3d absorption-spectra of Sr I through Sr IV
The extreme ultraviolet photoabsorption spectra of neutral to three-times-ionized strontium have been recorded in a comprehensive series of experiments with the dual laser-produced plasma technique. Striking differences were found in the spectra, which can be attributed to the transfer of oscillator strength from 3d→np to 3d→nf transitions at Sr2+ due to nf wave-function contraction. In Sr and Sr+, 3d→5p transitions dominate; in Sr2+, 3d→nf transitions are most intense, while in Sr3+ the 4p subshell opens and 3d→4p transitions are the strongest features. Partial cross sections for 3d→ɛf and 3d→ɛp photoionization were calculated and compared with experiment
Risk of fractures in half a million survivors of 20 cancers: a population-based matched cohort study using linked English electronic health records.
BACKGROUND: A history of multiple myeloma, prostate cancer, and breast cancer has been associated with adverse bone health, but associations across a broader range of cancers are unclear. We aimed to compare the risk of any bone fracture and major osteoporotic fractures in survivors of a wide range of cancers versus cancer-free individuals. METHODS: In this population-based matched cohort study, we used electronic health records from the UK Clinical Practice Research Datalink linked to hospital data. We included adults (aged ≥18 years) eligible for linkage, and we restricted the study start to Jan 2, 1998, onwards and applied administrative censoring on Jan 31, 2020. The cancer survivor group included survivors of the 20 most common cancers. Each individual with cancer was matched (age, sex, and general practice) to up to five controls (1:5) who were cancer-free. The primary outcomes were any bone fracture and any major osteoporotic fracture (pelvic, hip, wrist, spine, or proximal humeral fractures) occurring more than 1 year after index date (ie, the diagnosis date of the matched individual with cancer). We used Cox regression models, adjusted for shared risk factors, to estimate associations between cancer survivorship and bone fractures. FINDINGS: 578 160 adults with cancer diagnosed in 1998-2020 were matched to 3 226 404 cancer-free individuals. Crude incidence rates of fractures in cancer survivors ranged between 8·39 cases (95% CI 7·45-9·46) per 1000 person-years for thyroid cancer and 21·62 cases (20·18-23·18) per 1000 person-years for multiple myeloma. Compared with cancer-free individuals, the risk of any bone fracture was increased in 15 of 20 cancers, and of major osteoporotic fractures in 17 of 20 cancers. Effect sizes varied: adjusted hazard ratios (HRs) were largest for multiple myeloma (1·94, 95% CI 1·77-2·13) and prostate cancer (1·43, 1·39-1·47); HRs in the range 1·20-1·50 were seen for stomach, liver, pancreas, lung, breast, kidney, and CNS cancers; smaller associations (HR <1·20) were observed for malignant melanoma, non-Hodgkin lymphoma, leukaemia, and oesophageal, colorectal, and cervical cancers. Increased risks of major osteoporotic fracture were noted most substantially in multiple myeloma (2·25, 1·96-2·58) and CNS (2·12, 1·56-2·87), liver (1·62, 1·01-2·61), prostate (1·60, 1·53-1·67), and lung cancers (1·60, 1·44-1·77). Effect sizes tended to reduce over time since diagnosis but remained elevated for more than 5 years in several cancers, such as multiple myeloma and stomach, lung, breast, prostate, and CNS cancers. INTERPRETATION: Survivors of most types of cancer were at increased risk of bone fracture for several years after cancer, with variation by cancer type. These findings can help to inform mitigation and prevention strategies. FUNDING: Wellcome Trust
Isolation of digital dermatitis treponemes from hoof lesions in wild North American elk (Cervus elaphus) in Washington State, USA
Since 2008, a large increase in the numbers of cases of lameness have been seen in wild North American elk (Cervus elaphus) from Washington State, USA. The most recent cases manifested as foot lesions similar both clinically and pathologically to those seen in digital dermatitis (DD) in cattle and sheep, a disease with a bacterial etiopathogenesis. To determine whether the same bacteria considered responsible for DD are associated with elk lameness, lesion samples were subjected to bacterial isolation studies and PCR assays for three phylogroups of relevant DD treponemes. The DD treponemes were isolated from lesional tissues but not from control feet or other areas of the diseased foot (including the coronary band or interdigital space), suggesting that the bacteria are strongly associated with DD lesions and may therefore be causal. In addition, PCR analysis revealed that all three unique DD treponeme phylotypes were found in elk hoof disease, and in 23 of samples, all 3 DD-associated treponemes were present in lesions. Sequence analysis of the 16S rRNA gene showed that the elk lesion treponemes were phylogenetically almost identical to those isolated from cattle and sheep DD lesions. The isolates were particularly similar to two of the three culturable DD treponeme phylotypes: specifically, the Treponema medium/Treponema vincentii-like and Treponema phagedenis-like DD spirochetes. The third treponeme culturable phylogroup (Treponema pedis), although detected by PCR, was not isolated. This is the first report describing isolation of DD treponemes from a wildlife host, suggesting that the disease may be evolving to include a wider spectrum of cloven-hoofed animals. Copyright © 2015, American Society for Microbiology. All Rights Reserved
MHV Lagrangian for N=4 Super Yang-Mills
Here we formulate two field redefinitions for N=4 Super Yang-Mills in light
cone superspace that generates only MHV vertices in the new Lagrangian. After
careful consideration of the S-matrix equivalence theorem, we see that only the
canonical transformation gives the MHV Lagrangian that would correspond to the
CSW expansion. Being in superspace, it is easier to analyse the equivalence
theorem at loop level. We calculate the on shell amplitude for 4pt
MHV in the new lagrangian and
show that it reproduces the previously known form. We also briefly discuss the
relationship with the off-shell continuation prescription of CSW.Comment: 17 pages 4 figures, 2 sections and several references added typo
correcte
Hamiltonian evolutions of twisted gons in \RP^n
In this paper we describe a well-chosen discrete moving frame and their
associated invariants along projective polygons in \RP^n, and we use them to
write explicit general expressions for invariant evolutions of projective
-gons. We then use a reduction process inspired by a discrete
Drinfeld-Sokolov reduction to obtain a natural Hamiltonian structure on the
space of projective invariants, and we establish a close relationship between
the projective -gon evolutions and the Hamiltonian evolutions on the
invariants of the flow. We prove that {any} Hamiltonian evolution is induced on
invariants by an evolution of -gons - what we call a projective realization
- and we give the direct connection. Finally, in the planar case we provide
completely integrable evolutions (the Boussinesq lattice related to the lattice
-algebra), their projective realizations and their Hamiltonian pencil. We
generalize both structures to -dimensions and we prove that they are
Poisson. We define explicitly the -dimensional generalization of the planar
evolution (the discretization of the -algebra) and prove that it is
completely integrable, providing also its projective realization
Reconstruction Mechanism of FCC Transition-Metal (001) Surfaces
The reconstruction mechanism of (001) fcc transition metal surfaces is
investigated using a full-potential all-electron electronic structure method
within density-functional theory. Total-energy supercell calculations confirm
the experimental finding that a close-packed quasi-hexagonal overlayer
reconstruction is possible for the late 5-metals Ir, Pt, and Au, while it is
disfavoured in the isovalent 4 metals (Rh, Pd, Ag). The reconstructive
behaviour is driven by the tensile surface stress of the unreconstructed
surfaces; the stress is significantly larger in the 5 metals than in 4
ones, and only in the former case it overcomes the substrate resistance to the
required geometric rearrangement. It is shown that the surface stress for these
systems is due to charge depletion from the surface layer, and that the
cause of the 4th-to-5th row stress difference is the importance of relativistic
effects in the 5 series.Comment: RevTeX 3.0, 12 pages, 1 PostScript figure available upon request] 23
May 199
Surface energy and stability of stress-driven discommensurate surface structures
A method is presented to obtain {\it ab initio} upper and lower bounds to
surface energies of stress-driven discommensurate surface structures, possibly
non-periodic or exhibiting very large unit cells. The instability of the
stressed, commensurate parent of the discommensurate structure sets an upper
bound to its surface energy; a lower bound is defined by the surface energy of
an ideally commensurate but laterally strained hypothetical surface system. The
surface energies of the phases of the Si(111):Ga and Ge(111):Ga systems and the
energies of the discommensurations are determined within eV.Comment: 4 pages RevTeX. 2 Figures not included. Ask for a hard copy (through
regular mail) to [email protected]
Chern-Simons Solitons, Toda Theories and the Chiral Model
The two-dimensional self-dual Chern--Simons equations are equivalent to the
conditions for static, zero-energy solutions of the -dimensional gauged
nonlinear Schr\"odinger equation with Chern--Simons matter-gauge dynamics. In
this paper we classify all finite charge solutions by first
transforming the self-dual Chern--Simons equations into the two-dimensional
chiral model (or harmonic map) equations, and then using the Uhlenbeck--Wood
classification of harmonic maps into the unitary groups. This construction also
leads to a new relationship between the Toda and chiral model
solutions
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