"Hayatım bir serenattı"

Taha Toros Arşivi, Dosya No: 15-Fahrünnisa Zeidİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

Fausto Zonaro:Court painter of Sultan Abdul Hamid II

Taha Toros Arşivi, Dosya No: 98-Fausto Zonaroİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

"My life played me a serenade"

Taha Toros Arşivi, Dosya No: 15-Fahrünnisa Zeidİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033

Sentinel Node Identification Rate and Nodal Involvement in the EORTC 10981-22023 AMAROS Trial

Background The randomized EORTC 10981-22023 AMAROS trial investigates whether breast cancer patients with a tumor-positive sentinel node biopsy (SNB) are best treated with an axillary lymph node dissection (ALND) or axillary radiotherapy (ART). The aim of the current substudy was to evaluate the identification rate and the nodal involvement. Methods The first 2,000 patients participating in the AMAROS trial were evaluated. Associations between the identification rate and technical, patient-, and tumor-related factors were evaluated. The outcome of the SNB procedure and potential further nodal involvement was assessed. Results In 65 patients, the sentinel node could not be identified. As a result, the sentinel node identification rate was 97% (1,888 of 1,953). Variables affecting the success rate were age, pathological tumor size, histology, year of accrual, and method of detection. The SNB results of 65% of the patients (n = 1,220) were negative and the patients underwent no further axillary treatment. The SNB results were positive in 34% of the patients (n = 647), including macrometastases (n = 409, 63%), micrometastases (n = 161, 25%), and isolated tumor cells (n = 77, 12%). Further nodal involvement in patients with macrometastases, micrometastases, and isolated tumor cells undergoing an ALND was 41, 18, and 18%, respectively. Conclusions With a 97% detection rate in this prospective international multicenter study, the SNB procedure is highly effective, especially when the combined method is used. Further nodal involvement in patients with micrometastases and isolated tumor cells in the sentinel node was similar—both were 18%

A history of the French in London: liberty, equality, opportunity

This book examines, for the first time, the history of the social, cultural, political and economic presence of the French in London, and explores the multiple ways in which this presence has contributed to the life of the city. The capital has often provided a place of refuge, from the Huguenots in the 17th century, through the period of the French Revolution, to various exile communities during the 19th century, and on to the Free French in the Second World War. It also considers the generation of French citizens who settled in post-war London, and goes on to provide insights into the contemporary French presence by assessing the motives and lives of French people seeking new opportunities in the late 20th and early 21st centuries. It analyses the impact that the French have had historically, and continue to have, on London life in the arts, gastronomy, business, industry and education, manifest in diverse places and institutions from the religious to the political via the educational, to the commercial and creative industries