132 research outputs found
Comparison of Three Dimensional Partially and Fully Depleted SOI MOSFET Characteristics Using Mathcad
In this Paper, comparison of three Dimensional characteristics between partially and fully depleted Silicon-On-Insulator (SOI MOSFET) is presented, this is done through 3D device modeling using mathcad, based on the numerical solution of three dimensional Poisson’s equation. Behavior of Various Parameters like Surface Potential, Threshold Voltage, Electric field and Drain current are presented in this paper
Effects of lengthscales and attractions on the collapse of hydrophobic polymers in water
We present results from extensive molecular dynamics simulations of collapse
transitions of hydrophobic polymers in explicit water focused on understanding
effects of lengthscale of the hydrophobic surface and of attractive
interactions on folding. Hydrophobic polymers display parabolic, protein-like,
temperature-dependent free energy of unfolding. Folded states of small
attractive polymers are marginally stable at 300 K, and can be unfolded by
heating or cooling. Increasing the lengthscale or decreasing the polymer-water
attractions stabilizes folded states significantly, the former dominated by the
hydration contribution. That hydration contribution can be described by the
surface tension model, , where the surface
tension, , is lengthscale dependent and decreases monotonically with
temperature. The resulting variation of the hydration entropy with polymer
lengthscale is consistent with theoretical predictions of Huang and Chandler
(Proc. Natl. Acad. Sci.,97, 8324-8327, 2000) that explain the blurring of
entropy convergence observed in protein folding thermodynamics. Analysis of
water structure shows that the polymer-water hydrophobic interface is soft and
weakly dewetted, and is characterized by enhanced interfacial density
fluctuations. Formation of this interface, which induces polymer folding, is
strongly opposed by enthalpy and favored by entropy, similar to the
vapor-liquid interface.Comment: 24 pages, 5 figure
Approaches to Impose e-penalty Using Vahan Smart Card for Improving Road and Transport Safety with the Help of ICT: An E-Governanace Endeavour
AbstractWith the help of information communication technology (ICT) and computer science, an effective e-Governance should provide an efficient solution for the offenders, who violate the traffic rules and cause unnatural deaths due to breaking of signals or rash driving in INDIA. Many Government Plans have been executed and running successfully like VAHAN and SARATHI related to transportation. This paper proposed some approaches to penalize the offenders electronically and automatically, who violate the traffic rules on road. Penalty can be imposed on offenders using EPS and Vahan Smart Card with the help of RFID and a software flow with wired and wireless e-centre architecture and hybrid approaches
Cavern Wall Support Requirements in a Hydro-Electric Project
Construction of a 23m wide, 57m high, and 210m long underground power house cavern is in progress as a part of the multi-purpose Sardar Sarovar Project in India. The rock mass around the cavern is basalt which is intruded by a number of dolerite dykes. In view of the high side walls of the cavern, and the presence of a 1 to 2m thick shear zone running across the cavern width, a comprehensive approach was worked out for estimation of the wall support requirements. The approach included estimation of the roof support requirements using the four available approaches, and comparison of these requirements with the roof support system actually provided, and established as safe and adequate by the instrumentation data of six years. A favourable comparison established the reliability of the approaches used, and the most reliable of these approaches, i.e., the Barton\u27s approach was then used with confidence for estimation of the wall support requirements
Enhanced Production of Protective Antigen, a Potent Diagnostic Protein of Bacillus anthracis, the Causative Agent of Anthrax
Protective antigen (PA) produced by Bacillus anthracis is a highly immunogenic protein. Therefore, it has significant importance in serodiagnosis as well as a vaccine candidate for anthrax. In the present study, codons for PA gene were optimised and synthesised for its expression in Escherichia coli. Various expression conditions were optimised for scaled up production of rPA. The final yield of affinity chromatography purified protein was 40.8 mg/l during batch fermentation. For further purification, affinity purified protein was diafiltered and subjected to anion exchange chromatography. SDS-PAGE and Western blot was used to characterise the purified rPA protein. The diagnostic potential of purified rPA was evaluated in Western blot using standards reference serum AVR 801 and cutaneous anthrax clinical sera. The results of the present study established the optimum production of rPA in E. coli after codon optimisation for its subsequent use in diagnosis of anthrax infection
Numerical Simulation and Mathematical Modeling of 3D DG SOI MOSFET with the Influence of Biasing with Back Gate
Design consideration of a fully depleted SOI (Silicon-On-Insulator) MOSFET device by three dimensional
mathematical modeling is presented in this paper. To the best of our knowledge, when our device is
fabricated in nanometer regime, the threshold voltage changes due to various effects. Back gate voltage
plays a significant role on the controlling of threshold voltage. Separation of variable is used to solve the
Poisson’s three dimensional equation, analytically with suitable boundary conditions for the threshold
voltage of double gate SOI MOSFET with the influence of biasing with back gate. In this work, changes in
threshold voltage has been calculated and demonstrated that how short channel effects and DIBL can be
suppressed with application of Back Gate bias voltage
Design Device for Subthreshold Slope in DG Fully Depleted SOI MOSFE
In this paper, we discuss how a short channel effects can be suppressed and how a threshold voltage
fluctuation can be minimized and better control of subthreshold slope by the impact of the back gate bias and
control of gate work function of a fully depleted SOI (Silicon-On-Insulator) MOSFET. The fluctuation in the
threshold voltage and subthreshold slope are due to short channel effects. The Back gate voltage plays a
significant role on the threshold voltage and thin buried oxide is used to suppress the short-channel effects and
is used to keep a low value of the subthreshold slope are described in this paper. It is shown that how short
channel effects can be suppressed in order to improve subthreshold slope
Comparison of Three Dimensional Partially and Fully Depleted SOI MOSFET Characteristics Using Mathcad
In this Paper, comparison of three Dimensional characteristics between partially and fully depleted Silicon-On-Insulator (SOI MOSFET) is presented, this is done through 3D device modeling using mathcad, based on the numerical solution of three dimensional Poisson’s equation. Behavior of Various Parameters like Surface Potential, Threshold Voltage, Electric field and Drain current are presented in this paper
A Rapid Flow through Membrane Enzyme Linked Immunosorbent Assay for Bacillus anthracis using Surface Array Protein as a Biomarker
Anthrax, caused by Bacillus anthracis is an important disease of biowarfare and public health importance. It is imperative to develop a simple system which can detect and differentiate B. anthracis from other closely related species. The surface array protein (Sap), which is secreted during the early growth phase of bacteria can be an important biomarker for detection of B. anthracis. In the present study, we have developed a rapid flow through membrane ELISA for detection of B. anthracis. Polyclonal antibodies were used to develop a sandwich plate ELISA, which could detect 3.9 ng/ml of recombinant Sap. B. anthracis bacteria grown in culture broth could be detected after 5 h of growth. Finally, a rapid flow through membrane ELISA was developed which can be accomplished just within 2 minutes, instead of 3-4 h as required in sandwich plate ELISA. The results established that the developed flow through membrane ELISA may be used for detection of B. anthracis. The proposed method is rapid, safe and user friendly for detection of B. anthracis culture
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