Dual Frequency Electronically Controlled Radiation Beam Reconfigurable slotted Antenna for Detection of a Stationary or Nonstationary Target

A dual-frequency and radiation pattern reconfigurable microstrip patch antenna for detecting a stationary as well as a non-stationary target is described. Six angular patches, that collectively form a circular shape, are used. All the six patches radiate one by one after a fixed interval of time and their feed controlling is done by six PIN diodes. The switching of PIN diodes is controlled by an embedded biasing network. This antenna provides radiation beam scanning characteristics. It gives the main lobe scanning at every 60o clockwise (or anticlockwise) continuously by applying a signal to patches one by one. The purpose of introducing the slot is to get the radiation pattern in the desired direction since by changing the length, width, and position of the slot, the direction of the radiation pattern can be controlled. The slotted antenna operates in a C band with two frequencies 4.21 GHz and 4.82 GHz and provides a radiation pattern, 90o apart from each other. The scanning rate of 0.6 deg/ms is obtained; however, the scanning rate can be changed with the help of ATMEGA 2560 microcontroller. This compact Microstrip patch antenna can be widely used for short-range applications i.e. ground surveillance radar, missile control, mobile battlefield surveillance for military and many other applications in a modern wireless communication system. The designed antenna along with the switching application will be able to track the stationary as well as a non-stationary target

Study on Magnetic Materials for Removal of Water Pollutants

Water is a primary element for all living things, and we need water for each and every day-to-day activity related to agricultural, industrial, and domestic cares and, thus, its quality influences all aspects of human life including energy, food, health, and economy. Safe drinking water is our primary need to protect our life and thus developing efficient and affordable techniques for water treatment to access potable water to the humanity. Water pollution is one of the severe environmental and health problems worldwide. Pollutants in water can be of organic, inorganic, heavy metals, microbial, and radioactive species, which may be in different forms viz. suspended, dissolved, or dispersed materials. The water quality is mainly affected by industrial discharges, agricultural activities, mismanagement of hazardous materials, etc. Nowadays, nanotechnology offers the possibility of an efficient removal of water pollutants including metals, organic dyes, bacteria, parasites, etc. Magnetic nanomaterials like iron oxide (Fe3O4) are very promising materials used in water decontamination particularly for heavy metals and dyestuffs because of their ease of separation through external magnet, high surface area, unique morphology as well as their high stability. These materials can be used as adsorbent, photocatalyst, and coagulating agents for water remediation based on their composite materials or surface functionalities

Application Scanning and Ipv6 Assessment For MS-SQL Server

This paper attempts to present a solution that allows the users to scan the remote host machine on a network and to assess IPv6 enablement for MS-SQL. It aims to detect the hardware and the software installed on that machine. This goal is achieved by the use of Windows Application Programming Interface (API) through Windows Management Instrumentation (WMI) Scripts which handles the registry. WMI Scripts are used to connect to the registry of a remote host machine that reads the installed path of the software and hardware details of that machine. First, it will detect the underlying Operating System whether it can support IPv6 or not. If the underlying operating system can support IPv6, then only applications running on it can run on IPv6 enabled network. So for this the system also assesses the IPv6 enablement of MS-SQL Server

Macrophage Polarization Is Decisive for Chronic Bacterial Infection-Induced Carcinogenesis

Macrophages are the special cells of the immune system and play both immunological and physiological role. One of the peculiar characteristics of macrophages is that they are double-edged and highly plastic component of immune system. Due to this characteristic, they are responsible for both progressions as well control of a variety of inflammatory, infectious and metabolic diseases and cancer. These are found in the body in three major phenotypes, which are known as M0 (also known as naïve); M1 (classically activated macrophages); and/or M2 (alternatively activated macrophages) at normal physiological conditions. We have been exploring macrophages in context of bacterial infection and previously demonstrated that M2 polarization of M1 effector alveolar macrophages during chronic/persistent Chlamydia pneumonia, Mycobacterium tuberculosis and Helicobacter pylori pathogens are decisive for the infection induced cancer development in host. Since chronic infection with these pathogens has been associated with adenocarcinoma, therefore, we feel that disruption of macrophage plasticity plays crucial role in the host for the development of cancer. On the basis of this, we propose that in such pathological conditions, management of M1/M2 imbalance is paramount for minimizing the risk of developing cancer by chronic and persistent infection

3D In Vitro Neuron on a Chip for Probing Calcium Mechanostimulation

The evolution of tissue on a chip systems holds promise for mimicking the response of biological functionality of physiological systems. One important direction for tissue on a chip approaches are neuron‐based systems that could mimic neurological responses and lessen the need for in vivo experimentation. For neural research, more attention has been devoted recently to understanding mechanics due to issues in areas such as traumatic brain injury (TBI) and pain, among others. To begin to address these areas, a 3D Nerve Integrated Tissue on a Chip (NITC) approach combined with a Mechanical Excitation Testbed (MET) System is developed to impose external mechanical stimulation toward more realistic physiological environments. PC12 cells differentiated with nerve growth factor, which were cultured in a controlled 3D scaffolds, are used. The cells are labeled in a 3D NITC system with Fluo‐4‐AM to examine their calcium response under mechanical stimulation synchronized with image capture. Understanding the neural responses to mechanical stimulation beyond 2D systems is very important for neurological studies and future personalized strategies. This work will have implications in a diversity of areas including tissue‐on‐a‐chip systems, biomaterials, and neuromechanics.Developing more physiologically relevant 3D neuron integrated systems with external mechanics with synchronized image capture enables understanding of cellular responses that are important for advancing future neural studies and personalized strategies. This work examines calcium response with respect to voice coil actuator controlled force profiles.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163437/3/adbi202000080-sup-0001-SuppMat.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163437/2/adbi202000080_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163437/1/adbi202000080.pd

Awareness and Attitude towards Plagiarism among Post Graduate Students and Research Scholars of Select Social Sciences Departments of Kurukshetra University and Panjab University, Chandigarh

This study explores the awareness and attitude towards plagiarism among postgraduate students and research scholars of Kurukshetra University, Kurukshetra (KU) and Panjab University, Chandigarh (PU). The findings of the questionnaire based study reveal that 53.64% of KU and 79.9% respondents of PU were acquainted with the term plagiarism. More than 41% respondents became aware of this term in their present university and more than half of the total respondents came to know about this concept during last one year. Only 23.97% had attended plagiarism awareness programmes. The understanding and attitude towards plagiarism needs greater attention. Maximum 88.35% respondents considered ‘Using someone’s ideas/words without acknowledging his/her’ as plagiarism while 48.63% did not consider ‘Helping your friend/classmate write a paper that must be submitted by him/her as an assignment’ as plagiarism. The main reason of plagiarism was lack of proper understanding of the concept and therefore it is suggested that awareness programmes on plagiarism and training programmes on methods of citation should be conducted

TRADITIONAL DIETARY PATTERN OF INDIAN FOOD AND ITS SCIENTIFIC BASIS: AN OVERVIEW

India is a country where different type of languages, culture & food habits are in use. There is tremendous regional diversity in their daily diets. Indian cuisine reflects a more than 5,000 year history of various groups and cultures interacting with the subcontinent, leading to diversity of flavors and regional cuisines found in modern-day India. Dietary pattern analysis is an emerging area of research. This study demonstrates the importance of elucidating the social and cultural contexts in which dietary behaviors exist, especially when considering contradictory mainstream approaches to health promotion. Most of the food items were developed by keeping the health aspect in mind and some of the foods were directly used as homemade medicine for some specific diseases as they had therapeutic value. The previous generations knew very well the medicinal value of some of the spices or other ingredients and as such made it a point to use that ingredient in some food recipe to add medicinal value in it. This made Indian cuisine rich in a wide variety and taste and also helpful for health. It also provides valuable information to develop qualitative measures for empirical assessment, develop and evaluate targeted interventions

Design and Performance Evaluation of An Arduino Based Activity Tracker

Fitness band is an activity tracker that monitors the overall health of the wearer and helps us to predict the fitness plan to be followed on the basis of the number of footstep of the wearer over span of time. The band is connected to an android app where it can show user the various stats monitored by the band and the possible health plan which can be used to achieve the necessary health goals. The fitness band will also help in informing family members in case of some medical emergency

Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets.

BackgroundLiposarcoma, the most common soft tissue tumor, is understudied cancer, and limited progress has been made in the treatment of metastatic disease. The Achilles heel of cancer often is their kinases that are excellent therapeutic targets. However, very limited knowledge exists of therapeutic critical kinase targets in liposarcoma that could be potentially used in disease management.MethodsLarge RNAi and small-molecule tyrosine kinase inhibitor screens were performed against the proliferative capacity of liposarcoma cell lines of different subtypes. Each small molecule inhibitor was either FDA approved or in a clinical trial.ResultsScreening assays identified several previously unrecognized targets including PTK2 and KIT in liposarcoma. We also observed that ponatinib, multi-targeted tyrosine kinase inhibitor, was the most effective drug with anti-growth effects against all cell lines. In vitro assays showed that ponatinib inhibited the clonogenic proliferation of liposarcoma, and this anti-growth effect was associated with apoptosis and cell cycle arrest at the G0/G1 phase as well as a decrease in the KIT signaling pathway. In addition, ponatinib inhibited in vivo growth of liposarcoma in a xenograft model.ConclusionsTwo large-scale kinase screenings identified novel liposarcoma targets and a FDA-approved inhibitor, ponatinib with clear anti-liposarcoma activity highlighting its potential therapy for treatment of this deadly tumor