ROLE OF TERMINALIA ARJUNA IN ISCHEMIC HEART DISEASE (HRIDAROGA): A REVIEW

Now days, life is becoming very stressful and fast. As many diseases originate due to this hectic lifestyle. One of the important disease is Hridaroga (Ischemic heart disease), which is responsible for many deaths in early age. In Ayurveda, Hridaroga & their symptoms are described in many textbooks. Management of Hridaroga is also very critical and important. In modern medicine, only expensive interventional procedures are described but on the other hand, Ayurvedic herbs are better, cost effective & good therapeutic option for IHD (Hridaroga). The review emphasizes on various properties of Terminalia arjuna. Many clinical & animal studies on T.arjuna show its effect on ECG changes, LV functions & myocardial ischaemic reperfusion injury-etc. Besides this it also has antiatherosclerotic, anticoagulant, anti-infarction, hypolipidemic & hypotensive properties. So, Ayurvedic drug (T. arjuna) is a better option for the treatment of IHD (Hridaroga) because it can improve the quality of life in individuals & potentially save millions of lives

Role of Panchakarma in Visha Chiktisa

Disease and death due to poisoning is a burning issue in worldwide. The term Poisoning not only limited upto animal and vegetable poisons, it can include Dooshivisha, Garavisha and various radiations. Ayurveda has described different methods of treatment in poisoning. Panchakarma therapy has great importance because it can remove toxins from deeper tissue level. Panchakarma procedures are used depending upon the route of entry of poison and absorption. This article concludes how Panchakarma procedures are useful in Visha Chikitsa as a detoxification therapy

A STUDY ON VISHAGHNA PROPERTY OF SHANKHPUSHPI (CONVOLVULUS PLURICAULIS CHOIS) W.S.R. TO SUB ACUTE TOXICITY IN ALBINO WISTAR RATS

Shankhpushpi (Convolvulus pluricaulis chois) is an indigenous and very significant herb which is considered as a gift of nature in Ayurveda. In Ayurvedic literature, Shankhpushpi is considered as Medhya rasayana means it enhances the knowledge, memory and retaining power of a person. Shankhpushpi which is well described and abundantly available is taken for the Vishaghna property also. Although, the Medhya property of Shankhpushpi is well marketed and used by different pharmaceutical companies but, the Vishaghna property of this miraculous drug should be researched and established as it may fulfil the long awaited gap of Ayurvedic antitoxic substance(Agad). In this study 24 albino wistar rats were divided in four groups such as group G1, G2, G3 & G4 with 6 rats in each group. Group G2, G3 & G4 had received PCM in dose 1000mg/kg body weight for 7 days to induce hepato-nephro toxicity while group G1 was normal control group which was kept on normal feeding. After inducing hepato-nephro toxicity the sample drug Shankhpushpi in Group G2 in the form of Churna and in group G3 in the form of aqueous extract (Kwatha) was administered while in group G4 only normal saline was administered for 28 days. On the basis of study it can be concluded that toxicity induced by 1000mg/kg body weight PCM did not cause any neurological manifestations. After 28 days administration of drug Shankhpushpi Churna as well as Kwatha in group G2 & group G3, body weight and food consumption in this group slightly increased while in group G4 no any significant changes were found. Therapeutic administration of Shankhpushpi as Churna as well as Kwatha significantly decreased PCM induced toxicity

PATHYA APATHYA: IMPACT AND ROLE IN LIFESTYLE DISORDERS

Ayurveda is an ancient and most trusted Indian system of medicine commonly used by Indians since time immemorial. Lifestyle diseases/ Metabolic diseases are described as diseases related to the way an individual or group of individuals live, also are referred under Non-Communicable Diseases. Over-crowding and rapid unplanned urbanization; globalization of unhealthy lifestyles is responsible for some of the major reasons for a sedentary life leading to these diseases. It includes arteriosclerosis, heart disease, stroke, obesity and type-2 diabetes, diseases related to smoking, alcohol and drug abuse. The contribution of metabolic risk factors such as high blood pressure, blood sugar, cholesterol and that of improper diet and alcohol use resulting in health loss. Therefore, the occurrence of these disorders has doubled in India over the past quarter of a century therefore it is the need of the hour to manage them diligently. Diet plays a key role to nourish life and balanced diet is very important for maintaining good health. In Ayurveda, wholesome diet is described which plays a very important role specifically rather than in modern medicine which emphasizes only on the components in the diet like proteins, carbohydrates, fats etc. Ayurveda additionally deals with various other aspects like combination of food article, their quantity, method of preparation, their emotional effect, nature of consumer including environmental considerations. Pathya and Apathya Ahara (dietary consideration) is a significant component of almost each and every prescription in Ayurveda therapy. Sometimes, Pathya-Apathya (dietary management) is itself an entire treatment

Contemporary and Ancient Review of Mosquitoes - A Review

Indian system of medicine plays an important part in health care system all over India. There are numerous allusions to mosquitoes in Indian writings from the Vedic era. The Atharvaveda makes special reference of mosquito shape, habitat, many varieties, behaviour, and even their presence throughout the year. The 67 different forms of Keet and their genesis were documented by Acharya Susruta in Kalpasthana, while Keet Visha describes five different types of Mashak in which Parvatiya Mashak is the most hazardous to people. There is also Mashak description In Charaka Samhita of chapter Visha Chikitsa. Numerous mosquito species have been identified in contemporary science. Mosquitoes are the most important group of blood sucking insects causing nuisance diseases to humans and other animals.  It follows that our ancestors' seers or philosophers were already aware of this

RISK FACTOR ASSESSMENT FOR ACNE VULGARIS IN HUMAN AND IMPLICATIONS FOR PUBLIC HEALTH INTERVENTIONS IN NORTH CENTRAL INDIA: A SURVEY-BASED STUDY

Background: Acne vulgaris is a very common dermatological problem of adolescence since the time immemorial. However, it is neither life threatening nor is a physical disability, but acne affects social and psychological functioning. Acne vulgaris is multifactorial, apart from basic factor of hormonal change and bacterial outbreak; there are several other factors that may influence the prevalence of acne.Methods: In the present study, populations were assessed for influence of various factors on acne prevalence. This cross-sectional study was a population based field study intending to discern the factors that influence the prevalence of acne in adolescents. The study carried out from April 2016 to October 2016 in north central India. For this survey, questionnaires were design to cover all the required information regarding occurrence of acne that include factors like gender, age, skin type, complexion, season of occurrence, dietary habit etc.Results: Acne vulgaris appears to be influenced by gender, age, seasonal variations, breakout area, complexion, skin types and dietary habits. Further, the influence of dietary habit on acne, by the consumption of dairy products or high-carbon diet has also been evaluated. Apart from depicting the vulnerable range of age (p=0.003288), sensitivity on various skin types (p=0.00039) and complexion (p=0.001355) on the basis of gender; This Field study on Acne Vulgaris, also reveals that the season has inordinate role in acne pervasiveness (p=0.115731).Conclusion: This study is helpful in categorizing the risk factors and evidencing the afflictions of acne in population thus, contributing health care planning. Â

Functional Antigenic Molecules of Different Life-Stages of Rodent Filariid, Acanthocheilonema viteae and Their Cross Reactivity with Human Filarial (Wuchereria bancrofti) Sera.

Proteins obtained by SDS-solubilisation of various developmental stages (adults, uterus contents, microfilariae and infective larvae) of the filariid Acanthocheilonema viteae were separated by SDS-polyacrylamide gel electrophoresis (SDS-PAGE) and electrophoretically transferred onto nitrocellulose filter sheets. The results showed minor differences in the protein pattern of adult worms, microfilariae, uterine contents and infective larvae. Immunoperoxidase staining of these antigens with infected mastomys sera showed that maximum number of antigens in infective larval stage were identified by the sera collected at prepatent stage of infection whereas in adult antigen maximum bands were recognized by sera from patent infection. A large number of microfilarial antigens were found to be immunoreactive during patent stage but only a few remained functional during latency. Uterine antigens possess a number of immunoreactive components which reacted with antibodies in sera of all stages of infection with maximum recognition by patent (microfilaraemic) serum. Cross reaction between A. viteae antigen and W. bancrofti human sera led to identification of a few common molecules which demonstrated the usefulness of antigens of rodent filariid A. viteae in immunodiagnosis or in evolving strategies for vaccination against human filariasis

Rasayana as panacea in Covid-19 w.s.r. to Janapadodhwamsa

In Ayurveda the foremost aim is to prolong life and to promote perfect health and secondary aim is to eradicate the disease and dysfunction of the body. Ayurveda science wreathe us with the knowledge of how to maintain long and disease-free life and code of conducts. Acharya Charaka has been described Janapadodhwamsa, in Viman Sthana and considered as the chapter of epidemiological study, where he mentioned the whole concept on handling the situation of pandemic state in which Rasayana have important contribution. Now, a days the pandemic state of SARS-CoV-2 and their new variants like U.K., Brazil and South Africa which have mutation properties causing pressure on health care system and which feels the necessity of internationally unified clear and collective actions by the individuals, communities, commercial bodies etc. due to the novelty of the virus. Hence, SARS-CoV-2 can be correlated with Janapadodhwamsa and Rasayana is panacea for this disease, which provide strength against the virus and improve the immune response towards this pandemic disease. This article focuses on information about mechanism of action of immune modulating effect of Rasayana Dravyas which should incorporate in day to day life and act as immune modulators

Excretory-Secretory antigens of rodent filariid, Acanthocheilonema viteae and their cross-reaction with human filarial sera

In vitro released products of adult filariid Acanthocheilonema viteae were characterized according to their SDS-PAGE profiles and immune recognition patterns by infected mastomys and by human sera. Adult worms survived well in the serum free media (HBSS; Sigma) more than ten days. SDS-PAGE analysis of E/S antigens revealed the molecules between 70 and 54.5kDa highly dominant whereas immune recognition with infected mastomys sera demonstrated the immunoreactivity in molecules present between 48.5 and 58kDa. Many of these cross-reacted with W. bancrofti infected human sera showing the sharing of antigens by the two filariid species. 143, 96, 74, 62, 44 and two below 26.6kDa of adult A. viteae E/S cross-reacted with human filarial sera. A number of molecules between 60 and 44kDa were found reactive with both mastomys and human sera demonstrating their possible use in diagnosis. Presence of common antigens between the rodent and human filariid and their shared immunoreactivity demonstrate the usefulness of A. viteae antigens in diagnosis/prophylaxis of human filariasis

Retinitis pigmentosa genetics: A study in Indian population

A total of 151 retinitis pigmentosa (RP) patients from 83 families were screened and the frequencies of different genetic categories studied. One hundred and ten patients out of 151 had a positive inheritance pattern, and autosomal recessive (AR) emerged as the predominant (53 out of 151), genetic pattern followed by isolated or sporadic (41 out of 151) cases. Further study of autosomal recessive cases revealed consanguinity as the main characteristic (49 out of 53) in the Indian population studied. Early onset and severe progression of disease was seen in the consanguineous group